Published in JAMA on July 24, 2013
Molecular findings among patients referred for clinical whole-exome sequencing. JAMA (2014) 6.46
Models of consent to return of incidental findings in genomic research. Hastings Cent Rep (2014) 2.25
Incidental findings of uncertain significance: To know or not to know - that is not the question. BMC Med Ethics (2016) 1.39
Comprehensive gene panels provide advantages over clinical exome sequencing for Mendelian diseases. Genome Biol (2015) 1.39
Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. Am J Hum Genet (2016) 1.35
Revealing the incidentalome when targeting the tumor genome. JAMA (2013) 1.27
Return of results in the genomic medicine projects of the eMERGE network. Front Genet (2014) 0.99
Translating personalized medicine using new genetic technologies in clinical practice: the ethical issues. Per Med (2014) 0.98
Disease variants in genomes of 44 centenarians. Mol Genet Genomic Med (2014) 0.96
The fiduciary relationship model for managing clinical genomic "incidental" findings. J Law Med Ethics (2014) 0.95
Societal preferences for the return of incidental findings from clinical genomic sequencing: a discrete-choice experiment. CMAJ (2015) 0.93
Clinical exome performance for reporting secondary genetic findings. Clin Chem (2014) 0.93
Managing incidental genomic findings in clinical trials: fulfillment of the principle of justice. PLoS Med (2014) 0.89
Getting personal: Head and neck cancer management in the era of genomic medicine. Head Neck (2015) 0.86
PATH-SCAN: a reporting tool for identifying clinically actionable variants. Pac Symp Biocomput (2014) 0.85
Cancer screening and genetics: a tale of two paradigms. Cancer Epidemiol Biomarkers Prev (2014) 0.84
Practical guidance on informed consent for pediatric participants in a biorepository. Mayo Clin Proc (2014) 0.83
A Clinical Service to Support the Return of Secondary Genomic Findings in Human Research. Am J Hum Genet (2016) 0.80
Incidental findings from clinical sequencing in Greece: reporting experts' attitudes. J Community Genet (2014) 0.79
Human subjects protection: an event monitoring committee for research studies of girls from breast cancer families. J Adolesc Health (2014) 0.78
Genetic testing of children for diseases that have onset in adulthood: the limits of family interests. Pediatrics (2014) 0.77
Genomic Testing: a Genetic Counselor's Personal Reflection on Three Years of Consenting and Testing. J Genet Couns (2015) 0.77
Clinical genomics: from a truly personal genome viewpoint. Hum Genet (2016) 0.76
Identification of Medically Actionable Secondary Findings in the 1000 Genomes. PLoS One (2015) 0.76
Newborn screening and the era of medical genomics. Semin Perinatol (2015) 0.76
Compare and contrast: a cross-national study across UK, USA and Greek experts regarding return of incidental findings from clinical sequencing. Eur J Hum Genet (2015) 0.75
A protocol for the identification and validation of novel genetic causes of kidney disease. BMC Nephrol (2015) 0.75
Which Results to Return: Subjective Judgments in Selecting Medically Actionable Genes. Genet Test Mol Biomarkers (2017) 0.75
Public's Views toward Return of Secondary Results in Genomic Sequencing: It's (Almost) All about the Choice. J Genet Couns (2017) 0.75
Clinical genome sequencing and population preferences for information about 'incidental' findings-From medically actionable genes (MAGs) to patient actionable genes (PAGs). PLoS One (2017) 0.75
Interest and Attitudes of Patients With Advanced Cancer With Regard to Secondary Germline Findings From Tumor Genomic Profiling. J Oncol Pract (2017) 0.75
The complete genome of an individual by massively parallel DNA sequencing. Nature (2008) 52.81
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genet Med (2013) 22.73
Point-counterpoint. Patient autonomy and incidental findings in clinical genomics. Science (2013) 3.86
Technical report: Ethical and policy issues in genetic testing and screening of children. Genet Med (2013) 3.86
Ethical and policy issues in genetic testing and screening of children. Pediatrics (2013) 3.03
Genetic discrimination and life insurance: a systematic review of the evidence. BMC Med (2013) 1.55
Strong association of de novo copy number mutations with autism. Science (2007) 27.84
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science (2008) 14.26
Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood (2006) 5.05
The MacArthur Treatment Competence Study. III: Abilities of patients to consent to psychiatric and medical treatments. Law Hum Behav (1995) 3.57
Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade. J Exp Med (2007) 3.51
The therapeutic misconception: problems and solutions. Med Care (2002) 3.05
Therapeutic misconception and the appreciation of risks in clinical trials. Soc Sci Med (2004) 2.97
Use of leverage to improve adherence to psychiatric treatment in the community. Psychiatr Serv (2005) 2.62
Capacity to provide informed consent for participation in schizophrenia and HIV research. Am J Psychiatry (2002) 2.41
The capacity to appoint a proxy and the possibility of concurrent proxy directives. Behav Sci Law (2006) 2.37
Models of consent to return of incidental findings in genomic research. Hastings Cent Rep (2014) 2.25
Mental health training for law enforcement professionals. J Am Acad Psychiatry Law (2005) 2.24
Proxy and surrogate consent in geriatric neuropsychiatric research: update and recommendations. Am J Psychiatry (2004) 2.20
Evaluating psychiatric disability: differences by forensic expertise. J Am Acad Psychiatry Law (2011) 2.04
A new brief instrument for assessing decisional capacity for clinical research. Arch Gen Psychiatry (2007) 1.96
The evolution of consent forms for research: a quarter century of changes. IRB (2010) 1.92
Consent form readability and educational levels of potential participants in mental health research. Psychiatr Serv (2007) 1.89
Outcomes of congenital diaphragmatic hernia in the modern era of management. J Pediatr (2013) 1.80
The MacArthur Treatment Competence Study. I: Mental illness and competence to consent to treatment. Law Hum Behav (1995) 1.77
Unrealistic optimism in early-phase oncology trials. IRB (2011) 1.75
Attitudes and practices among internists concerning genetic testing. J Genet Couns (2012) 1.75
Assessment of capacity to consent to research among older persons with schizophrenia, Alzheimer disease, or diabetes mellitus: comparison of a 3-item questionnaire with a comprehensive standardized capacity instrument. Arch Gen Psychiatry (2005) 1.75
Maintaining informed consent validity during lengthy research protocols. IRB (2008) 1.62
The MacArthur Treatment Competence Study. II: Measures of abilities related to competence to consent to treatment. Law Hum Behav (1995) 1.60
Determining when impairment constitutes incapacity for informed consent in schizophrenia research. Br J Psychiatry (2007) 1.56
Ebola virus disease cluster in the United States--Dallas County, Texas, 2014. MMWR Morb Mortal Wkly Rep (2014) 1.49
Researchers' views on return of incidental genomic research results: qualitative and quantitative findings. Genet Med (2013) 1.48
The capacity to vote of persons with serious mental illness. Psychiatr Serv (2009) 1.48
Correlates of treatment-related decision-making capacity among middle-aged and older patients with schizophrenia. Arch Gen Psychiatry (2004) 1.43
Preservation of the capacity to appoint a proxy decision maker: implications for dementia research. Arch Gen Psychiatry (2011) 1.41
Epidemiologic investigation of a 2007 outbreak of Serratia marcescens bloodstream infection in Texas caused by contamination of syringes prefilled with heparin and saline. Infect Control Hosp Epidemiol (2009) 1.41
BRCA1 and BRCA2 mutation carriers in the Breast Cancer Family Registry: an open resource for collaborative research. Breast Cancer Res Treat (2008) 1.40
Questions on conflict of interest. Am J Psychiatry (2010) 1.38
Multimedia consent for research in people with schizophrenia and normal subjects: a randomized controlled trial. Schizophr Bull (2008) 1.37
The Congenital Heart Disease Genetic Network Study: rationale, design, and early results. Circ Res (2013) 1.35
Do clinicians follow a risk-sensitive model of capacity-determination? An experimental video survey. Psychosomatics (2006) 1.33
Twenty-five years of therapeutic misconception. Hastings Cent Rep (2008) 1.32
Observational study of spinal muscular atrophy type 2 and 3: functional outcomes over 1 year. Arch Neurol (2011) 1.32
Can psychiatry cross the quality chasm? Improving the quality of health care for mental and substance use conditions. Am J Psychiatry (2007) 1.30
The Declaration of Helsinki and clinical trials: a focus on placebo-controlled trials in schizophrenia. Am J Psychiatry (2003) 1.29
Analysis of significance patterns identifies ubiquitous and disease-specific gene-expression signatures in patient peripheral blood leukocytes. Ann N Y Acad Sci (2005) 1.28
Disclosures of Huntington disease risk within families: patterns of decision-making and implications. Am J Med Genet A (2007) 1.28
A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response. PLoS One (2007) 1.26
Assessment of therapeutic misconception in older schizophrenia patients with a brief instrument. Am J Psychiatry (2006) 1.25
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Res (2011) 1.22
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome. Diabetes (2013) 1.19
Competence to consent to research among long-stay inpatients with chronic schizophrenia. Psychiatr Serv (2003) 1.16
Application of ROMA (representational oligonucleotide microarray analysis) to patients with cytogenetic rearrangements. Genet Med (2005) 1.15
The contribution of de novo and rare inherited copy number changes to congenital heart disease in an unselected sample of children with conotruncal defects or hypoplastic left heart disease. Hum Genet (2013) 1.15
Deliberative assessment of surrogate consent in dementia research. Alzheimers Dement (2010) 1.14
A direct comparison of research decision-making capacity: schizophrenia/schizoaffective, medically ill, and non-ill subjects. Schizophr Res (2008) 1.12
Decision-making about reproductive choices among individuals at-risk for Huntington's disease. J Genet Couns (2007) 1.11
Disclosure of information to potential subjects on research recruitment web sites. IRB (2008) 1.11
Issues for DSM-V: DSM-V should include a conceptual issues work group. Am J Psychiatry (2008) 1.10
Genetic testing in psychiatry: a review of attitudes and beliefs. Psychiatry (2011) 1.09
Ought we to require emotional capacity as part of decisional competence? Kennedy Inst Ethics J (1998) 1.08
Research ethics. To protect human subjects, review what was done, not proposed. Science (2012) 1.06
Willingness of subjects with thought disorder to participate in research. Schizophr Bull (2005) 1.04
The process of deciding about prophylactic surgery for breast and ovarian cancer: Patient questions, uncertainties, and communication. Am J Med Genet A (2010) 1.03
Information disclosure, subject understanding, and informed consent in psychiatric research. Law Hum Behav (1988) 1.03
Decisional capacity of severely depressed patients requiring electroconvulsive therapy. J ECT (2003) 1.03
Use of genetic tests among neurologists and psychiatrists: knowledge, attitudes, behaviors, and needs for training. J Genet Couns (2013) 1.03
Drug-free research in schizophrenia: an overview of the controversy. IRB (1996) 1.03
Competence to complete psychiatric advance directives: effects of facilitated decision making. Law Hum Behav (2007) 1.02
The silent majority: who speaks at IRB meetings? IRB (2012) 1.02
The challenge of informed consent and return of results in translational genomics: empirical analysis and recommendations. J Law Med Ethics (2014) 1.01
The reporting of monetary compensation in research articles. J Empir Res Hum Res Ethics (2007) 0.98
Effectiveness of a school district closure for pandemic influenza A (H1N1) on acute respiratory illnesses in the community: a natural experiment. Clin Infect Dis (2012) 0.97
Prevalence and correlates of adequate performance on a measure of abilities related to decisional capacity: differences among three standards for the MacCAT-CR in patients with schizophrenia. Schizophr Res (2006) 0.97
Assessing competence to complete psychiatric advance directives with the competence assessment tool for psychiatric advance directives. Compr Psychiatry (2004) 0.97
Consent for intravenous thrombolysis in acute stroke: review and future directions. Arch Neurol (2007) 0.95
Variability of judgments of capacity: experience of capacity evaluators in a study of research consent capacity. Psychosomatics (2011) 0.95
Solid phase capturable dideoxynucleotides for multiplex genotyping using mass spectrometry. Nucleic Acids Res (2002) 0.94
Incidental findings in the era of whole genome sequencing? Hastings Cent Rep (2013) 0.93
How closely do institutional review boards follow the common rule? Acad Med (2012) 0.93
Microcomputed tomography provides high accuracy congenital heart disease diagnosis in neonatal and fetal mice. Circ Cardiovasc Imaging (2013) 0.92
A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance. Cardiovasc Res (2007) 0.92
Molecular and functional analysis of SLC25A20 mutations causing carnitine-acylcarnitine translocase deficiency. Hum Mutat (2004) 0.92
Treatment-related decision-making capacity in middle-aged and older patients with psychosis: a preliminary study using the MacCAT-T and HCAT. Am J Geriatr Psychiatry (2002) 0.91
Longitudinal consent-related abilities among research participants with schizophrenia: results from the CATIE study. Schizophr Res (2011) 0.91
Tarasoff and the researcher: does the duty to protect apply in the research setting? Am Psychol (1989) 0.91
Non-invasive brain stimulation in the detection of deception: scientific challenges and ethical consequences. Behav Sci Law (2009) 0.91
Competence and consent to research: a critique of the recommendations of the National Bioethics Advisory Commission. Account Res (1999) 0.89
The participation of community members on medical institutional review boards. J Empir Res Hum Res Ethics (2012) 0.89
A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev (2012) 0.89
Anticipating issues related to increasing preimplantation genetic diagnosis use: a research agenda. Reprod Biomed Online (2008) 0.89
Violence and mental disorders: data and public policy. Am J Psychiatry (2006) 0.88
"Thinking about it for somebody else": Alzheimer's disease research and proxy decision makers' translation of ethical principles into practice. Am J Geriatr Psychiatry (2013) 0.87
Improving the quality of informed consent to research. IRB (2008) 0.87
How important is 'accuracy' of surrogate decision-making for research participation? PLoS One (2013) 0.87
Competing commitments in clinical trials. IRB (2009) 0.86
Civil commitment--the American experience. Isr J Psychiatry Relat Sci (2006) 0.86
Views of internists towards uses of PGD. Reprod Biomed Online (2012) 0.86
Mentally ill and non-mentally-ill patients' abilities to understand informed consent disclosures for medication: preliminary data. Law Hum Behav (1991) 0.86
Prompt control of an outbreak caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit. J Pediatr (2013) 0.86
Enrolling in deep brain stimulation research for depression: influences on potential subjects' decision making. Depress Anxiety (2011) 0.85
Alternative decision-makers' perspectives on assent and dissent for dementia research. Am J Geriatr Psychiatry (2013) 0.85