Published in PLoS One on July 30, 2013
Triggering the succinate receptor GPR91 enhances pressure overload-induced right ventricular hypertrophy. Int J Clin Exp Pathol (2014) 0.81
Reducing endoglin activity limits calcineurin and TRPC-6 expression and improves survival in a mouse model of right ventricular pressure overload. J Am Heart Assoc (2014) 0.80
Conditional knockout of activin like kinase-1 (ALK-1) leads to heart failure without maladaptive remodeling. Heart Vessels (2017) 0.78
Pressure overload leads to an increased accumulation and activity of mast cells in the right ventricle. Physiol Rep (2017) 0.75
TGF-beta signal transduction. Annu Rev Biochem (1998) 17.83
Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol (2009) 12.05
Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol (2006) 10.71
Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure. J Am Coll Cardiol (2001) 4.07
Right ventricular function in cardiovascular disease, part I: Anatomy, physiology, aging, and functional assessment of the right ventricle. Circulation (2008) 3.63
Transforming growth factor-beta function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats. Circulation (2002) 3.20
The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest (2009) 2.92
Left ventricular interaction with arterial load studied in isolated canine ventricle. Am J Physiol (1983) 2.91
Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats. Circulation (1998) 2.77
Comparative influence of load versus inotropic states on indexes of ventricular contractility: experimental and theoretical analysis based on pressure-volume relationships. Circulation (1987) 1.90
TGFbeta, cardiac fibroblasts, and the fibrotic response. Cardiovasc Res (2006) 1.77
Right ventricular failure following chronic pressure overload is associated with reduction in left ventricular mass: evidence for atrophic remodeling. J Am Coll Cardiol (2011) 1.74
Ventriculoarterial coupling in normal and failing heart in humans. Circ Res (1989) 1.62
Molecular and physiological alterations in murine ventricular dysfunction. Proc Natl Acad Sci U S A (1994) 1.59
Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction. Basic Res Cardiol (2008) 1.52
Determination of left ventricular end-systolic pressure-volume relationships by the conductance (volume) catheter technique. Circulation (1986) 1.47
The role of TGF-β in the pathogenesis of primary open-angle glaucoma. Cell Tissue Res (2011) 1.47
Molecular signature of a right heart failure program in chronic severe pulmonary hypertension. Am J Respir Cell Mol Biol (2011) 1.36
A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev Cell (2012) 1.29
The pressure-overloaded right ventricle in pulmonary hypertension. Chest (1998) 1.24
Role of transforming growth factor-β in inflammatory bowel disease and colitis-associated colon cancer. Inflamm Bowel Dis (2010) 1.23
Transforming growth factor-β1 induced epithelial-mesenchymal transition in hepatic fibrosis. Hepatogastroenterology (2012) 1.20
Inhibitors/antagonists of TGF-β system in kidney fibrosis. Nephrol Dial Transplant (2012) 1.15
Molecular and physiological characterization of RV remodeling in a murine model of pulmonary stenosis. Am J Physiol Heart Circ Physiol (2008) 1.14
Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure. Circulation (2012) 1.12
ACE2 improves right ventricular function in a pressure overload model. PLoS One (2011) 1.03
17 Beta-estradiol differentially affects left ventricular and cardiomyocyte hypertrophy following myocardial infarction and pressure overload. J Card Fail (2008) 1.02
Right ventricular infarction: identification by hemodynamic measurements before and after volume loading and correlation with noninvasive techniques. J Am Coll Cardiol (1984) 0.99
Ventricular systolic interdependence: volume elastance model in isolated canine hearts. Am J Physiol (1987) 0.98
Characteristics and outcome after hospitalization for acute right heart failure in patients with pulmonary arterial hypertension. Circ Heart Fail (2011) 0.95
The use of left ventricular end-ejection pressure and peak pressure in the estimation of the end-systolic pressure-volume relationship. Circulation (1984) 0.91
Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load. Eur J Heart Fail (2011) 0.91
Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8. Am J Physiol Cell Physiol (2011) 0.89
Targeting calcineurin and associated pathways in cardiac hypertrophy and failure. Expert Opin Ther Targets (2005) 0.85
Transforming growth factor signalling: a common pathway in pulmonary arterial hypertension and systemic sclerosis. Int J Clin Pract Suppl (2011) 0.81
Statin-associated myopathy. JAMA (2003) 7.22
Noninvasive positive-pressure ventilation for respiratory failure after extubation. N Engl J Med (2004) 7.03
Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. J Am Coll Cardiol (2007) 4.93
Molecular and cellular basis of cardiovascular gender differences. Science (2005) 4.37
Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude. Am Heart J (2003) 3.73
Challenges in end-of-life care in the ICU: statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003: executive summary. Crit Care Med (2004) 2.95
Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind, placebo-controlled pilot study. Crit Care Med (2010) 2.92
Statins, low-density lipoprotein cholesterol, and risk of cancer. J Am Coll Cardiol (2008) 2.77
Heated Humidified High-Flow Nasal Oxygen in Adults: Mechanisms of Action and Clinical Implications. Chest (2015) 2.66
Risk factors for extubation failure in patients following a successful spontaneous breathing trial. Chest (2006) 2.60
Echocardiographic predictors of adverse outcomes in primary pulmonary hypertension. J Am Coll Cardiol (2002) 2.50
Seeking worldwide professional consensus on the principles of end-of-life care for the critically ill. The Consensus for Worldwide End-of-Life Practice for Patients in Intensive Care Units (WELPICUS) study. Am J Respir Crit Care Med (2014) 2.46
Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science (2002) 2.45
Association between statin-associated myopathy and skeletal muscle damage. CMAJ (2009) 2.41
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure. Nat Med (2003) 2.33
Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab (2010) 2.27
Developing a new, national approach to surveillance for ventilator-associated events*. Crit Care Med (2013) 2.24
The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis. Circulation (2005) 2.19
Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology (2014) 2.17
Outcomes of patients with do-not-intubate orders treated with noninvasive ventilation. Crit Care Med (2004) 2.17
Effect of soy protein from differently processed products on cardiovascular disease risk factors and vascular endothelial function in hypercholesterolemic subjects. Am J Clin Nutr (2007) 2.15
Association between estrogen receptor alpha gene variation and cardiovascular disease. JAMA (2003) 2.10
HRT and the young at heart. N Engl J Med (2007) 2.07
Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury. Circ Res (2002) 2.05
Acute applications of noninvasive positive pressure ventilation. Chest (2003) 1.98
Baseline and on-treatment high-density lipoprotein cholesterol and the risk of cancer in randomized controlled trials of lipid-altering therapy. J Am Coll Cardiol (2010) 1.95
Does noninvasive positive pressure ventilation improve outcome in acute hypoxemic respiratory failure? A systematic review. Crit Care Med (2004) 1.95
Which patients with acute exacerbation of chronic obstructive pulmonary disease benefit from noninvasive positive-pressure ventilation? A systematic review of the literature. Ann Intern Med (2003) 1.95
Pulmonary complications of chronic neuromuscular diseases and their management. Muscle Nerve (2004) 1.92
Randomized clinical trial of aspirin and simvastatin for pulmonary arterial hypertension: ASA-STAT. Circulation (2011) 1.91
Assessment of peripheral vascular endothelial function in the ambulatory setting. Vasc Med (2007) 1.88
Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J (2009) 1.87
Noninvasive ventilation for critical care. Chest (2007) 1.85
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. J Clin Invest (2009) 1.79
Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury. Circulation (2012) 1.78
Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha. Proc Natl Acad Sci U S A (2004) 1.77
Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study. J Hypertens (2005) 1.77
Acute and chronic effects of sildenafil in patients with pulmonary arterial hypertension. Respir Med (2005) 1.75
17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling. Circ Res (2004) 1.74
Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society. Menopause (2008) 1.74
Secondary intervention after endovascular abdominal aortic aneurysm repair. Ann Surg (2009) 1.73
Selective endothelin A receptor antagonism with sitaxsentan for pulmonary arterial hypertension associated with connective tissue disease. Ann Rheum Dis (2007) 1.72
Noninvasive ventilation for acute respiratory failure near the end of life. Crit Care Med (2008) 1.65
Clinical utility of endothelial function testing: ready for prime time? Circulation (2003) 1.62
Ventricular assist device therapy normalizes inducible nitric oxide synthase expression and reduces cardiomyocyte apoptosis in the failing human heart. J Am Coll Cardiol (2005) 1.61
Successful determination of lower inflection point and maximal compliance in a population of patients with acute respiratory distress syndrome. Crit Care Med (2002) 1.60
Intermediate-term outcomes of endovascular treatment for symptomatic chronic mesenteric ischemia. J Vasc Surg (2009) 1.60
Mechanically unloading the left ventricle before coronary reperfusion reduces left ventricular wall stress and myocardial infarct size. Circulation (2013) 1.58
Effects of statins on vascular structure and function: a systematic review. Am J Med (2004) 1.57
Nocturnal noninvasive ventilation. Chest (2008) 1.56
Statin use is associated with enhanced collateralization of severely diseased coronary arteries. Am Heart J (2003) 1.51
Statins and interstitial lung disease: a systematic review of the literature and of food and drug administration adverse event reports. Chest (2008) 1.51
High-density lipoproteins: a consensus statement from the National Lipid Association. J Clin Lipidol (2013) 1.50
High blood pressure arising from a defect in vascular function. Proc Natl Acad Sci U S A (2008) 1.50
Balloon expandable stents facilitate right renal artery reconstruction during complex open aortic aneurysm repair. J Vasc Surg (2009) 1.48
Renal actions of RGS2 control blood pressure. J Am Soc Nephrol (2010) 1.48
Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species. Mol Endocrinol (2007) 1.47
Peripheral augmentation index and vascular inflammation in autosomal dominant polycystic kidney disease. Nephrol Dial Transplant (2011) 1.47
Sildenafil for pulmonary arterial hypertension associated with connective tissue disease. J Rheumatol (2007) 1.46
Risk of adverse events with concomitant use of atorvastatin or simvastatin and glucose-lowering drugs (thiazolidinediones, metformin, sulfonylurea, insulin, and acarbose). Am J Cardiol (2002) 1.43
Comparison of the safety and efficacy of a combination tablet of niacin extended release and simvastatin vs simvastatin monotherapy in patients with increased non-HDL cholesterol (from the SEACOAST I study). Am J Cardiol (2008) 1.43
Comparison of the frequency of adverse events in patients treated with atorvastatin or simvastatin. Am J Cardiol (2003) 1.42
Vascular endothelial dysfunction is associated with reversible myocardial perfusion defects in the absence of obstructive coronary artery disease. J Nucl Cardiol (2006) 1.41
Relation of pulse pressure to blood pressure response to exercise in patients with hypertrophic cardiomyopathy. Am J Cardiol (2010) 1.41
The pulmonary artery pulsatility index identifies severe right ventricular dysfunction in acute inferior myocardial infarction. Catheter Cardiovasc Interv (2012) 1.40
Hemodynamic effects of standard versus larger-capacity intraaortic balloon counterpulsation pumps. J Invasive Cardiol (2015) 1.38
Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells. J Biol Chem (2008) 1.38
Meta-analysis: statin therapy does not alter the association between low levels of high-density lipoprotein cholesterol and increased cardiovascular risk. Ann Intern Med (2010) 1.34
A novel mechanism for the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced vasorelaxation and increased endothelial nitric oxide synthase expression. Am Heart J (2002) 1.33
Utilization of noninvasive ventilation in acute care hospitals: a regional survey. Chest (2006) 1.32
Effects of statins on nonlipid serum markers associated with cardiovascular disease: a systematic review. Ann Intern Med (2003) 1.28
Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation. Circ Res (2008) 1.26
Developing a new, national approach to surveillance for ventilator-associated events: executive summary. Chest (2013) 1.20
Estrogen-induced smooth muscle cell growth is regulated by tuberin and associated with altered activation of platelet-derived growth factor receptor-beta and ERK-1/2. J Biol Chem (2004) 1.19
Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery disease. Am J Cardiol (2006) 1.19
A call to action: women and peripheral artery disease: a scientific statement from the American Heart Association. Circulation (2012) 1.19
Management of diseases of the descending thoracic aorta in the endovascular era: a Medicare population study. Ann Surg (2010) 1.16
Use of pulse wave and color flow Doppler echocardiography in mouse models of human disease. J Am Soc Echocardiogr (2002) 1.14
Estrogen receptor-alpha variants are associated with lipoprotein size distribution and particle levels in women: the Framingham Heart Study. Atherosclerosis (2005) 1.13
Hormone replacement therapy and the cardiovascular system lessons learned and unanswered questions. J Am Coll Cardiol (2006) 1.12
Noninvasive versus conventional ventilation to treat hypercapnic encephalopathy in chronic obstructive pulmonary disease. Intensive Care Med (2007) 1.12
Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure. Circulation (2012) 1.12
Noninvasive positive-pressure ventilation to treat hypercapnic coma secondary to respiratory failure. Chest (2005) 1.10
Effects of angiotensin II receptor blockade versus angiotensin-converting-enzyme inhibition on ventricular remodelling following myocardial infarction in the mouse. Clin Sci (Lond) (2003) 1.09
Role of 12-lipoxygenase in hypoxia-induced rat pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol (2005) 1.09
The 5-HT transporter transactivates the PDGFbeta receptor in pulmonary artery smooth muscle cells. FASEB J (2007) 1.09
The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression. J Am Coll Cardiol (2012) 1.08
Endovascular management of patients with critical limb ischemia. J Vasc Surg (2011) 1.07
Large brachial artery diameter is associated with angiographic coronary artery disease in women. Am Heart J (2002) 1.06