Published in Crit Care Med on May 01, 2002
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Positive end-expiratory pressure at minimal respiratory elastance represents the best compromise between mechanical stress and lung aeration in oleic acid induced lung injury. Crit Care (2007) 1.19
The Japanese guidelines for the management of sepsis. J Intensive Care (2014) 0.99
Effects of descending positive end-expiratory pressure on lung mechanics and aeration in healthy anaesthetized piglets. Crit Care (2006) 0.86
Role of airway recruitment and derecruitment in lung injury. Crit Rev Biomed Eng (2011) 0.81
Monitoring of intratidal lung mechanics: a Graphical User Interface for a model-based decision support system for PEEP-titration in mechanical ventilation. J Clin Monit Comput (2014) 0.80
Two methods of setting positive end-expiratory pressure in acute lung injury: an experimental computed tomography volumetric study. J Korean Med Sci (2007) 0.77
Optimized positive end-expiratory pressure--an elusive target. Crit Care Med (2002) 0.77
The quest for optimal positive end-expiratory pressure continues. Crit Care (2008) 0.75
End-Expiratory Volume and Oxygenation: Targeting PEEP in ARDS Patients. Lung (2015) 0.75
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56
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Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med (2004) 24.47
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
Noninvasive positive-pressure ventilation for respiratory failure after extubation. N Engl J Med (2004) 7.03
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. JAMA (2008) 6.29
Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program. Crit Care Med (2014) 5.70
The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States. Crit Care Med (2004) 5.23
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci (2004) 4.69
Efficacy of recombinant human erythropoietin in critically ill patients: a randomized controlled trial. JAMA (2002) 4.09
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology (2002) 3.79
Lactate measurements in sepsis-induced tissue hypoperfusion: results from the Surviving Sepsis Campaign database. Crit Care Med (2015) 3.55
RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. Neuron (2007) 3.30
Challenges in end-of-life care in the ICU: statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003: executive summary. Crit Care Med (2004) 2.95
Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind, placebo-controlled pilot study. Crit Care Med (2010) 2.92
Rationing critical care beds: a systematic review. Crit Care Med (2004) 2.86
Heated Humidified High-Flow Nasal Oxygen in Adults: Mechanisms of Action and Clinical Implications. Chest (2015) 2.66
End-of-life care for the critically ill: A national intensive care unit survey. Crit Care Med (2006) 2.61
Risk factors for extubation failure in patients following a successful spontaneous breathing trial. Chest (2006) 2.60
Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice. Neurobiol Dis (2008) 2.52
Echocardiographic predictors of adverse outcomes in primary pulmonary hypertension. J Am Coll Cardiol (2002) 2.50
Seeking worldwide professional consensus on the principles of end-of-life care for the critically ill. The Consensus for Worldwide End-of-Life Practice for Patients in Intensive Care Units (WELPICUS) study. Am J Respir Crit Care Med (2014) 2.46
An international survey: Public awareness and perception of sepsis. Crit Care Med (2009) 2.40
Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proc Natl Acad Sci U S A (2013) 2.30
Developing a new, national approach to surveillance for ventilator-associated events*. Crit Care Med (2013) 2.24
Outcomes of patients with do-not-intubate orders treated with noninvasive ventilation. Crit Care Med (2004) 2.17
Use of GRADE grid to reach decisions on clinical practice guidelines when consensus is elusive. BMJ (2008) 2.15
Acute applications of noninvasive positive pressure ventilation. Chest (2003) 1.98
Does noninvasive positive pressure ventilation improve outcome in acute hypoxemic respiratory failure? A systematic review. Crit Care Med (2004) 1.95
Which patients with acute exacerbation of chronic obstructive pulmonary disease benefit from noninvasive positive-pressure ventilation? A systematic review of the literature. Ann Intern Med (2003) 1.95
Pulmonary complications of chronic neuromuscular diseases and their management. Muscle Nerve (2004) 1.92
Randomized clinical trial of aspirin and simvastatin for pulmonary arterial hypertension: ASA-STAT. Circulation (2011) 1.91
Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency. Nat Genet (2007) 1.87
Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J (2009) 1.87
Noninvasive ventilation for critical care. Chest (2007) 1.85
Comparing clinician ratings of the quality of palliative care in the intensive care unit. Crit Care Med (2011) 1.81
Effectiveness of treatments for severe sepsis: a prospective, multicenter, observational study. Am J Respir Crit Care Med (2009) 1.80
Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation. Blood (2004) 1.78
Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain. Neuron (2002) 1.76
Acute and chronic effects of sildenafil in patients with pulmonary arterial hypertension. Respir Med (2005) 1.75
Selective endothelin A receptor antagonism with sitaxsentan for pulmonary arterial hypertension associated with connective tissue disease. Ann Rheum Dis (2007) 1.72
Noninvasive ventilation for acute respiratory failure near the end of life. Crit Care Med (2008) 1.65
Sex and haemodynamics in pulmonary arterial hypertension. Eur Respir J (2013) 1.61
Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice. Cardiovasc Res (2013) 1.60
Biomarkers: diagnosis and risk assessment in sepsis. Clin Chest Med (2008) 1.57
Nocturnal noninvasive ventilation. Chest (2008) 1.56
Noninvasive positive pressure ventilation in critical and palliative care settings: understanding the goals of therapy. Crit Care Med (2007) 1.55
Ectopic expression of CGG containing mRNA is neurotoxic in mammals. Hum Mol Genet (2009) 1.54
Evaluating the use of recombinant human activated protein C in adult severe sepsis: results of the Surviving Sepsis Campaign. Crit Care Med (2012) 1.51
PEEP in ARDS--how much is enough? N Engl J Med (2004) 1.50
A multifaceted intervention to improve compliance with process measures for ICU clinician communication with ICU patients and families. Crit Care Med (2013) 1.48
Proposed quality measures for palliative care in the critically ill: a consensus from the Robert Wood Johnson Foundation Critical Care Workgroup. Crit Care Med (2006) 1.48
Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning. Nat Med (2011) 1.47
Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome. Blood (2004) 1.46
Sepsis severity score: an internationally derived scoring system from the surviving sepsis campaign database*. Crit Care Med (2014) 1.46
Sildenafil for pulmonary arterial hypertension associated with connective tissue disease. J Rheumatol (2007) 1.46
Rationing in the intensive care unit. Crit Care Med (2006) 1.45
The world's major religions' points of view on end-of-life decisions in the intensive care unit. Intensive Care Med (2007) 1.43
Triage decision making for the elderly: doing the right thing. Crit Care Med (2012) 1.40
Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet (2004) 1.39
Dying in America. Crit Care Med (2004) 1.38
Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins. Hum Mol Genet (2006) 1.38
Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation. Am J Med Genet A (2007) 1.37
The ethical conduct of clinical research involving critically ill patients in the United States and Canada: principles and recommendations. Am J Respir Crit Care Med (2004) 1.36
Role for Msh5 in the regulation of Ig class switch recombination. Proc Natl Acad Sci U S A (2007) 1.35
Intensivists at night: putting resources in the right place. Crit Care (2013) 1.33
AGG interruptions within the maternal FMR1 gene reduce the risk of offspring with fragile X syndrome. Genet Med (2012) 1.33
Interruptions in the expanded ATTCT repeat of spinocerebellar ataxia type 10: repeat purity as a disease modifier? Am J Hum Genet (2005) 1.32
Utilization of noninvasive ventilation in acute care hospitals: a regional survey. Chest (2006) 1.32
Fragile X-related proteins regulate mammalian circadian behavioral rhythms. Am J Hum Genet (2008) 1.32
Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1. J Pharmacol Exp Ther (2006) 1.26
Haplotype and linkage disequilibrium architecture for human cancer-associated genes. Genome Res (2002) 1.26
Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models. J Neurophysiol (2009) 1.24
Perceptions of cost constraints, resource limitations, and rationing in United States intensive care units: results of a national survey. Crit Care Med (2008) 1.23
International differences in end-of-life attitudes in the intensive care unit: results of a survey. Arch Intern Med (2005) 1.22
Bmal1 and β-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced β-cell failure in mice. Mol Cell Biol (2013) 1.22
Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene. Behav Neurosci (2008) 1.21
Developing a new, national approach to surveillance for ventilator-associated events: executive summary. Chest (2013) 1.20
Mechanical ventilation in sepsis-induced acute lung injury/acute respiratory distress syndrome: an evidence-based review. Crit Care Med (2004) 1.20
Positive selection of a pre-expansion CAG repeat of the human SCA2 gene. PLoS Genet (2005) 1.19
Evidence for RNA-mediated toxicity in the fragile X-associated tremor/ataxia syndrome. Future Neurol (2009) 1.17
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med (2017) 1.15
Noninvasive versus conventional ventilation to treat hypercapnic encephalopathy in chronic obstructive pulmonary disease. Intensive Care Med (2007) 1.12
Noninvasive positive-pressure ventilation to treat hypercapnic coma secondary to respiratory failure. Chest (2005) 1.10
Role of 12-lipoxygenase in hypoxia-induced rat pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol (2005) 1.09
Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry. Crit Care (2010) 1.09
AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome. Neurobiol Dis (2011) 1.09
The 5-HT transporter transactivates the PDGFbeta receptor in pulmonary artery smooth muscle cells. FASEB J (2007) 1.09
Low-dose steroids in adult septic shock: results of the Surviving Sepsis Campaign. Intensive Care Med (2012) 1.08
Somatic and germline instability of the ATTCT repeat in spinocerebellar ataxia type 10. Am J Hum Genet (2004) 1.08
Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings. J Clin Invest (2003) 1.08
Agreement between Occupational Therapy Practice Framework classifications and occupational therapists' classifications. Am J Occup Ther (2007) 1.07
Brain natriuretic peptide in pulmonary arterial hypertension: biomarker and potential therapeutic agent. Drug Des Devel Ther (2009) 1.05
Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality. Crit Care (2012) 1.05
Controlled trial of oronasal versus nasal mask ventilation in the treatment of acute respiratory failure. Crit Care Med (2003) 1.05