O-linked N-acetylglucosamine cycling regulates mitotic spindle organization.

PubWeight™: 0.98‹?› | Rank: Top 15%

🔗 View Article (PMC 3779708)

Published in J Biol Chem on August 14, 2013

Authors

Ee Phie Tan1, Sarah Caro, Anish Potnis, Christopher Lanza, Chad Slawson

Author Affiliations

1: From the Department of Biochemistry and Molecular Biology.

Articles cited by this

A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A (2008) 10.07

Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Biol (2001) 9.18

Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell (2006) 6.46

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell (2003) 5.68

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell (2008) 5.38

Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J Cell Biol (2001) 5.34

Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. Cell (1999) 4.83

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. Nat Chem Biol (2008) 3.46

Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface. Mol Cell (2010) 3.44

Cell cycle regulation of a Xenopus Wee1-like kinase. Mol Biol Cell (1995) 3.13

Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. Science (2012) 3.05

Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal (2010) 2.79

Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis. J Biol Chem (2005) 2.74

CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis. J Cell Biol (2001) 2.72

A novel mechanism for activation of the protein kinase Aurora A. Curr Biol (2003) 2.68

Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev Cell (2006) 2.57

Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol Biol Cell (2002) 2.56

Beta-N-acetylglucosamine (O-GlcNAc) is part of the histone code. Proc Natl Acad Sci U S A (2010) 2.47

Diabetes and the accompanying hyperglycemia impairs cardiomyocyte calcium cycling through increased nuclear O-GlcNAcylation. J Biol Chem (2003) 2.24

Chromosome condensation by a human condensin complex in Xenopus egg extracts. J Biol Chem (2001) 2.17

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation. Oncogene (2000) 2.15

Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase. J Biol Chem (2002) 2.15

GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature (2011) 2.14

CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function. Dev Cell (2003) 1.91

Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts. Mol Biol Cell (1993) 1.87

O-GlcNAc signalling: implications for cancer cell biology. Nat Rev Cancer (2011) 1.87

Centromeres: unique chromatin structures that drive chromosome segregation. Nat Rev Mol Cell Biol (2011) 1.80

A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin. Mol Biol Cell (2008) 1.64

O-linked beta-N-acetylglucosaminyltransferase substrate specificity is regulated by myosin phosphatase targeting and other interacting proteins. J Biol Chem (2008) 1.64

The centromere geometry essential for keeping mitosis error free is controlled by spindle forces. Nature (2007) 1.64

Chromosomal instability and aneuploidy in cancer: from yeast to man. EMBO Rep (2012) 1.51

Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification. J Biol Chem (2009) 1.45

Microtubule assembly during mitosis - from distinct origins to distinct functions? J Cell Sci (2012) 1.42

Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly. Dev Cell (2010) 1.34

O-GlcNAc transferase regulates mitotic chromatin dynamics. J Biol Chem (2010) 1.33

The chromosomal passenger complex activates Polo kinase at centromeres. PLoS Biol (2012) 1.33

Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance. J Biol Chem (2008) 1.28

Phosphorylation network dynamics in the control of cell cycle transitions. J Cell Sci (2012) 1.26

β-N-Acetylglucosamine (O-GlcNAc) is a novel regulator of mitosis-specific phosphorylations on histone H3. J Biol Chem (2012) 1.25

Modification of histones by sugar β-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated. J Biol Chem (2011) 1.20

Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition. Mol Cell Proteomics (2009) 1.18

Mitotic CDKs control the metaphase-anaphase transition and trigger spindle elongation. Genes Dev (2008) 1.16

Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome. Mol Cell Proteomics (2011) 1.11

Phosphorylation at serine 331 is required for Aurora B activation. J Cell Biol (2011) 1.10

Nuclear Survivin expression is correlated with malignant behaviors of head and neck cancer together with Aurora-B. Oral Oncol (2010) 1.01

Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis. Cancer Res (2007) 0.98

Linked for life: temporal and spatial coordination of late mitotic events. Curr Opin Cell Biol (2004) 0.97

Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes. Chem Biol (2010) 0.94

Pituitary tumor transforming gene 1 regulates Aurora kinase A activity. Oncogene (2008) 0.92

TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation. J Cell Sci (2012) 0.87

The catalytic role of INCENP in Aurora B activation and the kinetic mechanism of Aurora B/INCENP. Biochem J (2009) 0.81