Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases.

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Published in Lancet Infect Dis on September 01, 2013

Authors

L Silvia Munoz-Price1, Laurent Poirel, Robert A Bonomo, Mitchell J Schwaber, George L Daikos, Martin Cormican, Giuseppe Cornaglia, Javier Garau, Marek Gniadkowski, Mary K Hayden, Karthikeyan Kumarasamy, David M Livermore, Juan J Maya, Patrice Nordmann, Jean B Patel, David L Paterson, Johann Pitout, Maria Virginia Villegas, Hui Wang, Neil Woodford, John P Quinn

Author Affiliations

1: Department of Medicine, Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. smunozprice@med.miami.edu

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Characterization and sequence analysis of extended-spectrum-{beta}-lactamase-encoding genes from Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates collected during tigecycline phase 3 clinical trials. Antimicrob Agents Chemother (2008) 1.08

Intercontinental spread from Israel to Colombia of a KPC-3-producing Klebsiella pneumoniae strain. Clin Microbiol Infect (2011) 1.08

Transfer from high-acuity long-term care facilities is associated with carriage of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae: a multihospital study. Infect Control Hosp Epidemiol (2012) 1.07

Environmental KPC-producing Escherichia coli isolates in Portugal. Antimicrob Agents Chemother (2011) 1.07

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Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis (2010) 35.92

Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev (2008) 17.77

Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21

Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev (2005) 15.72

Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis (2006) 14.63

Global spread of Carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis (2011) 13.18

Targeted versus universal decolonization to prevent ICU infection. N Engl J Med (2013) 13.05

Metallo-beta-lactamases: the quiet before the storm? Clin Microbiol Rev (2005) 12.07

Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis (2002) 11.30

Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med (2009) 10.60

Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study. Lancet Infect Dis (2011) 9.43

The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23

Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center. Antimicrob Agents Chemother (2004) 7.99

Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob Agents Chemother (2004) 7.96

Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother (2007) 7.84

Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15. J Antimicrob Chemother (2007) 7.81

Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents (2006) 7.58

Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections. Lancet Infect Dis (2006) 7.36

Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene. Antimicrob Agents Chemother (2008) 7.06

CTX-M: changing the face of ESBLs in Europe. J Antimicrob Chemother (2006) 6.58

Nova regulates brain-specific splicing to shape the synapse. Nat Genet (2005) 6.58

Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. Clin Infect Dis (2011) 6.57

Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res (2006) 6.45

Multiplex PCR for detection of acquired carbapenemase genes. Diagn Microbiol Infect Dis (2011) 6.44

Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258. Antimicrob Agents Chemother (2009) 6.33

Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet (2006) 6.32

Dissemination of clonally related Escherichia coli strains expressing extended-spectrum beta-lactamase CTX-M-15. Emerg Infect Dis (2008) 6.21

Characterization of a strain of community-associated methicillin-resistant Staphylococcus aureus widely disseminated in the United States. J Clin Microbiol (2006) 5.97

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell (2009) 5.81

Rapid detection of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis (2012) 5.81

Three decades of beta-lactamase inhibitors. Clin Microbiol Rev (2010) 5.54

Discovery of tissue-specific exons using comprehensive human exon microarrays. Genome Biol (2007) 5.53

Peritoneal dialysis-related infections recommendations: 2005 update. Perit Dial Int (2005) 5.49

First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. Antimicrob Agents Chemother (2007) 5.36

Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain. J Antimicrob Chemother (2010) 5.35

A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use. Infect Control Hosp Epidemiol (2005) 5.26

Decreased susceptibility to cephalosporins among gonococci: data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England and Wales, 2007-2011. Lancet Infect Dis (2013) 4.91

Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance. FEMS Microbiol Rev (2011) 4.89

Emergence of Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs) in the community. J Antimicrob Chemother (2005) 4.87

Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center. Antimicrob Agents Chemother (2006) 4.80

Carbapenem resistance in Enterobacteriaceae: here is the storm! Trends Mol Med (2012) 4.77

International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections. Ann Intern Med (2004) 4.75

The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii. FEMS Microbiol Lett (2006) 4.73

Multiplex PCR for rapid detection of genes encoding acquired metallo-beta-lactamases. J Antimicrob Chemother (2006) 4.73

First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America. Antimicrob Agents Chemother (2006) 4.66

Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae. J Antimicrob Chemother (2005) 4.65

Unusual intron conservation near tissue-regulated exons found by splicing microarrays. PLoS Comput Biol (2006) 4.63

OXA-48-like carbapenemases: the phantom menace. J Antimicrob Chemother (2012) 4.63

Plasmid-mediated imipenem-hydrolyzing enzyme KPC-2 among multiple carbapenem-resistant Escherichia coli clones in Israel. Antimicrob Agents Chemother (2006) 4.50

Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada. Antimicrob Agents Chemother (2004) 4.46

Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii. J Bacteriol (2008) 4.42

Diversity, epidemiology, and genetics of class D beta-lactamases. Antimicrob Agents Chemother (2009) 4.33

Better tests, better care: improved diagnostics for infectious diseases. Clin Infect Dis (2013) 4.27

Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase blaKPC-2 gene. Emerg Infect Dis (2010) 4.25

Emergence of metallo-β-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia. Antimicrob Agents Chemother (2010) 4.23

Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature (2009) 4.21

Genetic features of blaNDM-1-positive Enterobacteriaceae. Antimicrob Agents Chemother (2011) 4.16

Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC in a Klebsiella pneumoniae isolate from France. Antimicrob Agents Chemother (2005) 4.15

Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use. JAMA (2003) 4.09

Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns. Emerg Infect Dis (2002) 4.08

The emerging NDM carbapenemases. Trends Microbiol (2011) 4.08

10 x '20 Progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America. Clin Infect Dis (2013) 4.07

Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases. J Antimicrob Chemother (2005) 4.04

Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital. Antimicrob Agents Chemother (2007) 4.03

bla(VIM-2) cassette-containing novel integrons in metallo-beta-lactamase-producing Pseudomonas aeruginosa and Pseudomonas putida isolates disseminated in a Korean hospital. Antimicrob Agents Chemother (2002) 4.01

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. Genome Res (2009) 3.99

Identification of Acinetobacter baumannii by detection of the blaOXA-51-like carbapenemase gene intrinsic to this species. J Clin Microbiol (2006) 3.98

The beta-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter. Trends Microbiol (2006) 3.96

Vancomycin-resistant Staphylococcus aureus in the United States, 2002-2006. Clin Infect Dis (2008) 3.95

Comparative analysis of Acinetobacters: three genomes for three lifestyles. PLoS One (2008) 3.94

Insertion sequence ISEcp1B is involved in expression and mobilization of a bla(CTX-M) beta-lactamase gene. Antimicrob Agents Chemother (2003) 3.94

Extended-spectrum beta-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV- and CTX-M-type beta-lactamases. Antimicrob Agents Chemother (2003) 3.92

Biochemical analysis of the ceftazidime-hydrolysing extended-spectrum beta-lactamase CTX-M-15 and of its structurally related beta-lactamase CTX-M-3. J Antimicrob Chemother (2002) 3.91

How to detect NDM-1 producers. J Clin Microbiol (2010) 3.84

Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA. J Antimicrob Chemother (2009) 3.82

Treatment outcome of bacteremia due to KPC-producing Klebsiella pneumoniae: superiority of combination antimicrobial regimens. Antimicrob Agents Chemother (2012) 3.80

Emergence of plasmid-mediated quinolone resistance in Escherichia coli in Europe. Antimicrob Agents Chemother (2005) 3.77

Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases. Clin Infect Dis (2004) 3.75

Outbreak of extended-spectrum beta-lactamase VEB-1-producing isolates of Acinetobacter baumannii in a French hospital. J Clin Microbiol (2003) 3.74