Published in Biophys J on August 20, 2013
Piezo1 links mechanical forces to red blood cell volume. Elife (2015) 1.33
Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension. Nat Commun (2016) 1.06
Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proc Natl Acad Sci U S A (2014) 1.03
Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia. Nat Commun (2015) 0.97
Red blood cell Gardos channel (KCNN4):the essential determinant of erythrocyte dehydration in Hereditary Xerocytosis. Haematologica (2017) 0.75
Piezo1 protein induces the apoptosis of human osteoarthritis-derived chondrocytes by activating caspase-12, the signaling marker of ER stress. Int J Mol Med (2017) 0.75
Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science (2010) 6.29
Piezo proteins are pore-forming subunits of mechanically activated channels. Nature (2012) 3.54
Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers. Nature (2004) 3.12
Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1. Blood (2013) 2.27
Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1. Proc Natl Acad Sci U S A (2013) 1.86
Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis. Blood (2012) 1.76
Ion transport pathology in the mechanism of sickle cell dehydration. Physiol Rev (2005) 1.64
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels. Nat Commun (2013) 1.60
Gating the mechanical channel Piezo1: a comparison between whole-cell and patch recording. Channels (Austin) (2012) 1.43
Sensing pressure with ion channels. Trends Neurosci (2012) 1.42
Human PIEZO1: removing inactivation. Biophys J (2013) 1.07
Polycystin-1 and -2 dosage regulates pressure sensing. Cell (2009) 3.36
Regulation of synaptic strength and AMPA receptor subunit composition by PICK1. J Neurosci (2004) 2.19
TREK-1, a K+ channel involved in polymodal pain perception. EMBO J (2006) 2.02
A phospholipid sensor controls mechanogating of the K+ channel TREK-1. EMBO J (2004) 1.98
Revisiting TRPC1 and TRPC6 mechanosensitivity. Pflugers Arch (2007) 1.81
The TREK K2P channels and their role in general anaesthesia and neuroprotection. Trends Pharmacol Sci (2004) 1.71
Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels. EMBO J (2003) 1.65
K+-dependent cerebellar granule neuron apoptosis. Role of task leak K+ channels. J Biol Chem (2003) 1.56
Sensing pressure with ion channels. Trends Neurosci (2012) 1.42
Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton. EMBO Rep (2005) 1.41
Canonical TRP channels and mechanotransduction: from physiology to disease states. Pflugers Arch (2010) 1.38
The versatile nature of the calcium-permeable cation channel TRPP2. EMBO Rep (2006) 1.34
Multiple modalities converge on a common gate to control K2P channel function. EMBO J (2011) 1.34
The mechano-gated K(2P) channel TREK-1. Eur Biophys J (2008) 1.29
TRP channels and mechanosensory transduction: insights into the arterial myogenic response. Pflugers Arch (2008) 1.24
AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels. EMBO J (2006) 1.24
Lysophosphatidic acid-operated K+ channels. J Biol Chem (2004) 1.19
A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J (2010) 1.18
The TASK background K2P channels: chemo- and nutrient sensors. Trends Neurosci (2007) 1.17
Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K(+) channel. Biochem Biophys Res Commun (2002) 1.15
Polycystins and renovascular mechanosensory transduction. Nat Rev Nephrol (2010) 1.13
Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells. EMBO Rep (2013) 1.02
Up- and down-regulation of the mechano-gated K(2P) channel TREK-1 by PIP (2) and other membrane phospholipids. Pflugers Arch (2007) 0.99
Cardiovascular polycystins: insights from autosomal dominant polycystic kidney disease and transgenic animal models. Trends Cardiovasc Med (2006) 0.98
Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels. J Mol Cell Cardiol (2009) 0.98
Molecular basis of the mammalian pressure-sensitive ion channels: focus on vascular mechanotransduction. Prog Biophys Mol Biol (2008) 0.96
Antipsychotics inhibit TREK but not TRAAK channels. Biochem Biophys Res Commun (2007) 0.92
Membrane potential-regulated transcription of the resting K+ conductance TASK-3 via the calcineurin pathway. J Biol Chem (2006) 0.90
Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension. Lab Invest (2010) 0.86
Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels. Cell Rep (2012) 0.86
Selective involvement of serum response factor in pressure-induced myogenic tone in resistance arteries. Arterioscler Thromb Vasc Biol (2012) 0.79
The background K(+) channel TASK-3 is regulated at both the transcriptional and post-transcriptional levels. Biochem Biophys Res Commun (2006) 0.78
Molecular strategies for studying oxygen-sensitive K+ channels. Methods Enzymol (2004) 0.76
A special issue on physiological aspects of mechanosensing. Pflugers Arch (2014) 0.75