Aurora kinases in head and neck cancer.

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Published in Lancet Oncol on September 01, 2013

Authors

Ranee Mehra1, Ilya G Serebriiskii, Barbara Burtness, Igor Astsaturov, Erica A Golemis

Author Affiliations

1: Program in Developmental Therapeutics, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. ranee.mehra@fccc.edu

Associated clinical trials:

Alisertib (MLN8237) or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma | NCT01482962

Study of TAK-733 in Combination With Alisertib in Adult Patients With Advanced Nonhematologic Malignancies | NCT01613261

Study to Assess Safety and Tolerability of MLN8237, In Combination With Erlotinib to Treat Non-Small Cell Lung Cancer | NCT01471964

Alisertib in Adults With Nonhematological Malignancies, Followed by Alisertib in Lung, Breast, Head and Neck or Gastroesophageal Malignancies | NCT01045421

Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma | NCT01567709

A Phase I/II Study of Paclitaxel, Carboplatin and YM155 (Survivin Suppressor) in Subjects With Solid Tumors (Phase I) and Advanced Non-Small Cell Lung Carcinoma (Phase II) | NCT01100931

A Phase 1 Study of MLN8237 in Patients With Advanced Solid Tumors Including Castration-Resistant Prostate Cancer Receiving a Standard Docetaxel Regimen | NCT01094288

MLN8237 in Head and Neck Cancer | NCT01540682

MLN8237 and Pazopanib in Combination for Solid Tumors | NCT01639911

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