PubRank

Kenn Gerdes

Author PubWeight™ 110.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res 2005 6.61
2 The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell 2003 6.01
3 Dysfunctional MreB inhibits chromosome segregation in Escherichia coli. EMBO J 2003 4.37
4 The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex. Mol Microbiol 2005 4.15
5 Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA. J Mol Biol 2003 3.76
6 Bacterial persistence by RNA endonucleases. Proc Natl Acad Sci U S A 2011 3.52
7 Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol Microbiol 2002 3.44
8 RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA. Mol Microbiol 2003 3.32
9 (p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity. Cell 2013 3.28
10 F-actin-like filaments formed by plasmid segregation protein ParM. EMBO J 2002 2.91
11 Prokaryotic DNA segregation by an actin-like filament. EMBO J 2002 2.78
12 Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon. Genes Dev 2002 2.75
13 Plasmid segregation mechanisms. Annu Rev Genet 2005 2.69
14 Bacterial mitosis: ParM of plasmid R1 moves plasmid DNA by an actin-like insertional polymerization mechanism. Mol Cell 2003 2.60
15 Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system. Mol Microbiol 2004 2.29
16 HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea. J Bacteriol 2008 2.26
17 Movement and equipositioning of plasmids by ParA filament disassembly. Proc Natl Acad Sci U S A 2009 2.21
18 The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell 2009 2.01
19 Two higBA loci in the Vibrio cholerae superintegron encode mRNA cleaving enzymes and can stabilize plasmids. Mol Microbiol 2006 2.00
20 Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli. Genes Dev 2006 1.93
21 Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA. Proc Natl Acad Sci U S A 2011 1.92
22 Bacterial mitosis: partitioning protein ParA oscillates in spiral-shaped structures and positions plasmids at mid-cell. Mol Microbiol 2004 1.88
23 Regular cellular distribution of plasmids by oscillating and filament-forming ParA ATPase of plasmid pB171. Mol Microbiol 2006 1.82
24 Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol Microbiol 2009 1.76
25 A problem of persistence: still more questions than answers? Nat Rev Microbiol 2013 1.68
26 Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation. J Biol Chem 2008 1.62
27 Messenger RNA interferase RelE controls relBE transcription by conditional cooperativity. Mol Microbiol 2008 1.59
28 Molecular mechanism of bacterial persistence by HipA. Mol Cell 2013 1.48
29 Novel coiled-coil cell division factor ZapB stimulates Z ring assembly and cell division. Mol Microbiol 2008 1.41
30 Structural analysis of the ParR/parC plasmid partition complex. EMBO J 2007 1.40
31 RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB. J Mol Biol 2009 1.35
32 Spatial resolution of two bacterial cell division proteins: ZapA recruits ZapB to the inner face of the Z-ring. Mol Microbiol 2010 1.32
33 Delayed-relaxed response explained by hyperactivation of RelE. Mol Microbiol 2004 1.25
34 Translation affects YoeB and MazF messenger RNA interferase activities by different mechanisms. Nucleic Acids Res 2008 1.23
35 Ectopic production of VapCs from Enterobacteria inhibits translation and trans-activates YoeB mRNA interferase. Mol Microbiol 2009 1.19
36 Direct interaction of FtsZ and MreB is required for septum synthesis and cell division in Escherichia coli. EMBO J 2013 1.13
37 Conditional cooperativity in toxin-antitoxin regulation prevents random toxin activation and promotes fast translational recovery. Nucleic Acids Res 2012 1.06
38 Regulation of enteric vapBC transcription: induction by VapC toxin dimer-breaking. Nucleic Acids Res 2012 1.06
39 ParA ATPases can move and position DNA and subcellular structures. Curr Opin Microbiol 2011 1.05
40 FtsZ-ZapA-ZapB interactome of Escherichia coli. J Bacteriol 2011 1.05
41 Competitive inhibition of natural antisense Sok-RNA interactions activates Hok-mediated cell killing in Escherichia coli. Nucleic Acids Res 2006 1.04
42 Bacterial DNA segregation by the actin-like MreB protein. Trends Cell Biol 2005 1.04
43 Structural and thermodynamic characterization of the Escherichia coli RelBE toxin-antitoxin system: indication for a functional role of differential stability. Biochemistry 2007 1.04
44 The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interaction. Mol Microbiol 2006 1.03
45 RNA decay by messenger RNA interferases. Methods Enzymol 2008 1.02
46 Regulatory cross-talk in the double par locus of plasmid pB171. J Biol Chem 2006 1.01
47 Crystal structure of the VapBC toxin-antitoxin complex from Shigella flexneri reveals a hetero-octameric DNA-binding assembly. J Mol Biol 2011 1.01
48 Centromere pairing by a plasmid-encoded type I ParB protein. J Biol Chem 2007 1.00
49 VapC20 of Mycobacterium tuberculosis cleaves the sarcin-ricin loop of 23S rRNA. Nat Commun 2013 1.00
50 What is the mechanism of ParA-mediated DNA movement? Mol Microbiol 2010 0.97
51 A mechanism for ParB-dependent waves of ParA, a protein related to DNA segregation during cell division in prokaryotes. J Mol Biol 2003 0.95
52 Clustering versus random segregation of plasmids lacking a partitioning function: a plasmid paradox? Plasmid 2003 0.89
53 Partition-associated incompatibility caused by random assortment of pure plasmid clusters. Mol Microbiol 2005 0.87
54 ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics. MBio 2014 0.86
55 Centromere parC of plasmid R1 is curved. Nucleic Acids Res 2004 0.85
56 Protein expression, crystallization and preliminary X-ray crystallographic analysis of the isolated Shigella flexneri VapC toxin. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.82
57 Conditional cooperativity of toxin - antitoxin regulation can mediate bistability between growth and dormancy. PLoS Comput Biol 2013 0.81
58 Plasmid segregation: spatial awareness at the molecular level. J Cell Biol 2007 0.78
59 Crystallization of the HigBA2 toxin-antitoxin complex from Vibrio cholerae. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.78
60 CRP-dependent positive autoregulation and proteolytic degradation regulate competence activator Sxy of Escherichia coli. Mol Microbiol 2015 0.77
61 Microbiology. Dynamic instability of a bacterial engine. Science 2004 0.75