Published in Br J Cancer on September 12, 2013
Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a. Oncotarget (2014) 1.90
MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R. Oncotarget (2014) 0.99
Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells. Oncotarget (2014) 0.90
MicroRNA-139-5p inhibits cell proliferation and invasion by targeting insulin-like growth factor 1 receptor in human non-small cell lung cancer. Int J Clin Exp Pathol (2015) 0.85
Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma. Oncogene (2015) 0.85
Profiling the microRNA Expression in Human iPS and iPS-derived Retinal Pigment Epithelium. Cancer Inform (2014) 0.84
A novel small-molecule compound diaporine A inhibits non-small cell lung cancer growth by regulating miR-99a/mTOR signaling. Cancer Biol Ther (2014) 0.82
A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA). Int J Mol Sci (2015) 0.81
Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells. PLoS One (2014) 0.80
Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression. Mol Cancer Ther (2015) 0.79
MicroRNAs 99b-5p/100-5p Regulated by Endoplasmic Reticulum Stress are Involved in Abeta-Induced Pathologies. Front Aging Neurosci (2015) 0.78
Type I insulin-like growth factor receptor signaling in hematological malignancies. Oncotarget (2017) 0.76
miR-590 promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia by inhibiting RB1. Oncotarget (2016) 0.76
The functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapy. Onco Targets Ther (2015) 0.75
Changes in apoptotic microRNA and mRNA expression profiling in Caenorhabditis elegans during the Shenzhou-8 mission. J Radiat Res (2015) 0.75
Integrative Analysis of MicroRNA-Mediated Gene Signatures and Pathways Modulating White Blood Cell Count in Childhood Acute Lymphoblastic Leukemia. Biomark Insights (2017) 0.75
Prognostic significance of microRNA-100 in solid tumors: an updated meta-analysis. Onco Targets Ther (2017) 0.75
Altered expression and editing of miRNA-100 regulates iTreg differentiation. Nucleic Acids Res (2015) 0.75
Steroid Receptor-Associated Immunophilins: A Gateway to Steroid Signalling. Clin Biochem Rev (2015) 0.75
Pooling-analysis for diagnostic and prognostic value of MiRNA-100 in various cancers. Oncotarget (2017) 0.75
Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer (2006) 46.47
mTOR signaling in growth control and disease. Cell (2012) 29.21
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science (2004) 18.84
Acute lymphoblastic leukemia. N Engl J Med (2004) 7.83
MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer (2006) 5.37
FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell (2009) 4.48
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance. Cancer Cell (2006) 3.93
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology (2009) 3.01
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J Biol Chem (2004) 2.91
mTORC1 promotes survival through translational control of Mcl-1. Proc Natl Acad Sci U S A (2008) 2.50
A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. J Biol Chem (2001) 2.21
Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding. Endocrinology (2000) 2.08
miR-99 family of MicroRNAs suppresses the expression of prostate-specific antigen and prostate cancer cell proliferation. Cancer Res (2011) 2.02
Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer. J Urol (2005) 2.01
Molecular biology in breast cancer: intrinsic subtypes and signaling pathways. Cancer Treat Rev (2011) 1.98
Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia. Cancer Res (2009) 1.95
Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo. J Biol Chem (2002) 1.95
Management of metabolic effects associated with anticancer agents targeting the PI3K-Akt-mTOR pathway. J Clin Oncol (2012) 1.95
Glucocorticoid receptor phosphorylation differentially affects target gene expression. Mol Endocrinol (2008) 1.81
Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors. Cancer Res (2010) 1.80
mTOR signaling: implications for cancer and anticancer therapy. Br J Cancer (2006) 1.72
MicroRNA patterns associated with clinical prognostic parameters and CNS relapse prediction in pediatric acute leukemia. PLoS One (2009) 1.62
FKBP51, a novel T-cell-specific immunophilin capable of calcineurin inhibition. Mol Cell Biol (1995) 1.45
Immunophilin chaperones in steroid receptor signalling. Curr Top Med Chem (2003) 1.41
MiR-125 in normal and malignant hematopoiesis. Leukemia (2012) 1.41
Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms. Hum Mutat (2003) 1.37
Down-regulation of the microRNA-99 family members in head and neck squamous cell carcinoma. Oral Oncol (2012) 1.36
MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. Oncogene (2011) 1.35
High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling. J Exp Med (2011) 1.31
Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy. Expert Opin Ther Targets (2012) 1.27
The miR-99 family regulates the DNA damage response through its target SNF2H. Oncogene (2012) 1.24
Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta. Mol Cell Biol (2009) 1.24
FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway. Neoplasia (2008) 1.21
On the trail of the glucocorticoid receptor: into the nucleus and back. Traffic (2011) 1.16
MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R. PLoS One (2011) 1.15
Glucocorticoid modulation of cytokine signaling. Tissue Antigens (2006) 1.15
Structure-function analysis of squirrel monkey FK506-binding protein 51, a potent inhibitor of glucocorticoid receptor activity. Endocrinology (2005) 1.15
Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma. BMC Cancer (2012) 1.14
The role of FKBP5 in cancer aetiology and chemoresistance. Br J Cancer (2010) 1.14
Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis. Mol Endocrinol (2011) 1.13
MicroRNAs in B cell development and malignancy. J Hematol Oncol (2012) 1.08
T-cell acute lymphoblastic leukaemia: recent molecular biology findings. Br J Haematol (2011) 1.06
Targeted therapy in lymphoma. J Hematol Oncol (2010) 1.05
Evolution of the let-7 microRNA family. RNA Biol (2012) 0.97
The emerging role of large immunophilin FK506 binding protein 51 in cancer. Curr Med Chem (2011) 0.94
Erg and AP-1 as determinants of glucocorticoid response in acute lymphoblastic leukemia. Oncogene (2012) 0.91
The prospect of FKBP51 as a drug target. ChemMedChem (2012) 0.90
Upregulation of microRNA-100 predicts poor prognosis in patients with pediatric acute myeloid leukemia. Onco Targets Ther (2012) 0.87
EphB6 receptor modulates micro RNA profile of breast carcinoma cells. PLoS One (2011) 0.87
Proteomic evaluation of pathways associated with dexamethasone-mediated apoptosis and resistance in multiple myeloma. Br J Haematol (2007) 0.87
Interleukin-4 stimulates proliferation and growth of T-cell acute lymphoblastic leukemia cells by activating mTOR signaling. Leukemia (2008) 0.79
Calming down T cell acute leukemia. Cancer Cell (2012) 0.77
Systematic review and meta-analysis of randomized controlled trials comparing stapled haemorrhoidopexy with conventional haemorrhoidectomy. Br J Surg (2008) 1.74
MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. Oncogene (2011) 1.35
Macrophage-stimulating protein and RON receptor tyrosine kinase: potential regulators of macrophage inflammatory activities. Scand J Immunol (2002) 1.07
Sixteen cases of pulmonary sclerosing haemangioma: CT findings are not definitive for preoperative diagnosis. Clin Radiol (2011) 0.99
Significance of white blood cell count and its subtypes in patients with acute coronary syndrome. Eur J Clin Invest (2009) 0.96
Endobronchial eosinophils preferentially stimulate T helper cell type 2 responses. Allergy (2004) 0.94
Prognostic relevance and therapeutic implications of centromere protein F expression in patients with esophageal squamous cell carcinoma. Dis Esophagus (2012) 0.87
Factors influencing the degree of enhancement of prostate cancer on contrast-enhanced transrectal ultrasonography: correlation with biopsy and radical prostatectomy specimens. Br J Radiol (2012) 0.87
PCB congener specific oxidative stress response by microarray analysis using human liver cell line. Environ Int (2010) 0.85
MicroRNAs as regulators in normal hematopoietic and leukemia stem cells: current concepts and clinical implications. Curr Mol Med (2012) 0.83
Soluble CD86 protein in serum samples of patients with asthma. Thorax (2004) 0.80
Cutaneous adverse drug reactions in a hospital-based Chinese population. Clin Exp Dermatol (2010) 0.79
Screening and identification of the nucleic acid aptamers in nasopharyngeal carcinoma. Genet Mol Res (2013) 0.76
A clinical study on the effects of recombinant human colony stimulating factor on the expression of Bcl-2 in serum of patients with basal ganglia hemorrhage and its clinical significance. Eur Rev Med Pharmacol Sci (2017) 0.75