Published in EJNMMI Res on September 16, 2013
18F-labeling using click cycloadditions. Biomed Res Int (2014) 0.83
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol (1973) 47.81
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal Biochem (2005) 4.65
Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues. Cancer Res (1992) 3.66
Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases. Acc Chem Res (2007) 3.03
Pegylation: a novel process for modifying pharmacokinetics. Clin Pharmacokinet (2001) 2.23
Receptor-mediated folate accumulation is regulated by the cellular folate content. Proc Natl Acad Sci U S A (1986) 1.95
Folate receptors. Annu Rev Nutr (1996) 1.82
Folate-targeted therapies for cancer. J Med Chem (2010) 1.73
Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression. Bioconjug Chem (2007) 1.64
Studies of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate by cultured human KB cells. J Biol Chem (1985) 1.50
Folate-mediated targeting: from diagnostics to drug and gene delivery. Drug Discov Today (2001) 1.36
Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning. Eur J Nucl Med Mol Imaging (2003) 1.34
Demonstration of a high affinity folate binder in human cell membranes and its characterization in cultured human KB cells. J Biol Chem (1979) 1.32
Indium-111-DTPA-folate as a potential folate-receptor-targeted radiopharmaceutical. J Nucl Med (1998) 1.14
Synthesis, purification, and tumor cell uptake of 67Ga-deferoxamine--folate, a potential radiopharmaceutical for tumor imaging. Bioconjug Chem (1996) 1.05
Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals. Nucl Med Biol (2003) 1.03
"Click-to-chelate": in vitro and in vivo comparison of a 99mTc(CO)3-labeled N(tau)-histidine folate derivative with its isostructural, clicked 1,2,3-triazole analogue. Bioconjug Chem (2008) 0.98
Fluorine-18 click radiosynthesis and preclinical evaluation of a new 18F-labeled folic acid derivative. Bioconjug Chem (2008) 0.92
[18F]fluoro-deoxy-glucose folate: a novel PET radiotracer with improved in vivo properties for folate receptor targeting. Bioconjug Chem (2012) 0.90
Folate based radiopharmaceuticals for imaging and therapy of cancer and inflammation. Curr Pharm Des (2012) 0.88
Synthesis and preclinical evaluation of a folic acid derivative labeled with 18F for PET imaging of folate receptor-positive tumors. J Nucl Med (2006) 0.87
Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis. Arthritis Res Ther (2013) 0.87
Novel synthesis and preclinical evaluation of folic acid derivatives labeled with (18)F-[FDG] for PET imaging of folate receptor-positive tumors. Nucl Med Biol (2012) 0.83
Tumor targeting using 67Ga-DOTA-Bz-folate--investigations of methods to improve the tissue distribution of radiofolates. Nucl Med Biol (2011) 0.81
Radiosynthesis and preclinical evaluation of 3'-Aza-2'-[(18)F]fluorofolic acid: a novel PET radiotracer for folate receptor targeting. Bioconjug Chem (2013) 0.81
A new 18F-labeled folic acid derivative with improved properties for the PET imaging of folate receptor-positive tumors. J Nucl Med (2010) 0.81
Dose-dependent effects of (anti)folate preinjection on 99mTc-radiofolate uptake in tumors and kidneys. Nucl Med Biol (2007) 0.78
Preparation of a 125I-labelled conjugate of pteroylglutamic acid and its use in a radio ligand assay of folate in blood. Med Lab Sci (1981) 0.77
18F-labeled bombesin analog for specific and effective targeting of prostate tumors expressing gastrin-releasing peptide receptors. J Nucl Med (2011) 0.94
Radiosynthesis and preclinical evaluation of 3'-Aza-2'-[(18)F]fluorofolic acid: a novel PET radiotracer for folate receptor targeting. Bioconjug Chem (2013) 0.81
Synthesis, radiolabeling, in vitro and in vivo evaluation of [18F]-FPECMO as a positron emission tomography radioligand for imaging the metabotropic glutamate receptor subtype 5. Nucl Med Biol (2009) 0.81
5-(2-18F-fluoroethoxy)-L-tryptophan as a substrate of system L transport for tumor imaging by PET. J Nucl Med (2012) 0.81
Imaging atherosclerotic plaque inflammation via folate receptor targeting using a novel 18F-folate radiotracer. Mol Imaging (2014) 0.80
Increase of [(18)F]FLT tumor uptake in vivo mediated by FdUrd: toward improving cell proliferation positron emission tomography. Mol Imaging Biol (2011) 0.80
Characterization of different osteosarcoma phenotypes by PET imaging in preclinical animal models. J Nucl Med (2013) 0.80
Synthesis and preclinical evaluation of a new C-6 alkylated pyrimidine derivative as a PET imaging agent for HSV1-tk gene expression. Am J Nucl Med Mol Imaging (2013) 0.77
(18) F-labeled folic acid derivatives for imaging of the folate receptor via positron emission tomography. J Labelled Comp Radiopharm (2013) 0.77
Synthesis and evaluation of a C-6 alkylated pyrimidine derivative for the in vivo imaging of HSV1-TK gene expression. Nucl Med Biol (2011) 0.77
Radioiodinated folic acid conjugates: evaluation of a valuable concept to improve tumor-to-background contrast. Mol Pharm (2012) 0.76
A novel (68)Ga-labeled pteroic acid-based pet tracer for tumor imaging via the folate receptor. Recent Results Cancer Res (2013) 0.76
Synthesis and evaluation of biphenyl compounds as kinesin spindle protein inhibitors. Chem Biodivers (2013) 0.75
18F-Radiolabeling, preliminary evaluation of folate-pHPMA conjugates via PET. Macromol Biosci (2014) 0.75
Synthesis and biological evaluation of a new acyclic pyrimidine derivative as a probe for imaging herpes simplex virus type 1 thymidine kinase gene expression. Molecules (2013) 0.75
Methoxymethyl (MOM) group nitrogen protection of pyrimidines bearing C-6 acyclic side-chains. Molecules (2011) 0.75
Multiple Time-Point 68Ga-PSMA I&T PET/CT for Characterization of Primary Prostate Cancer: Value of Early Dynamic and Delayed Imaging. Clin Nucl Med (2017) 0.75