Published in Acc Chem Res on July 27, 2007
Strategies in the design of nanoparticles for therapeutic applications. Nat Rev Drug Discov (2010) 7.48
Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy. Int J Nanomedicine (2008) 2.20
Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic. Crit Rev Ther Drug Carrier Syst (2009) 1.73
Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery. Nat Rev Drug Discov (2014) 1.61
X-ray-computed tomography contrast agents. Chem Rev (2012) 1.52
Direct in vivo evidence of activated macrophages in human osteoarthritis. Osteoarthritis Cartilage (2016) 1.41
Extracellularly activated nanocarriers: a new paradigm of tumor targeted drug delivery. Mol Pharm (2009) 1.38
Folate-mediated intracellular drug delivery increases the anticancer efficacy of nanoparticulate formulation of arsenic trioxide. Mol Cancer Ther (2009) 1.27
Folate-decorated nanogels for targeted therapy of ovarian cancer. Biomaterials (2011) 1.21
Targeted delivery systems for oligonucleotide therapeutics. AAPS J (2009) 1.19
"Clickable" polymer-caged nanobins as a modular drug delivery platform. J Am Chem Soc (2009) 1.18
Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival. Proc Natl Acad Sci U S A (2013) 1.16
An antibody-recruiting small molecule that targets HIV gp120. J Am Chem Soc (2009) 1.15
Receptor-targeted nanocarriers for therapeutic delivery to cancer. Mol Membr Biol (2010) 1.11
The effect of chemotherapy on expression of folate receptor-alpha in ovarian cancer. Cell Oncol (Dordr) (2011) 1.10
Cell-specific, activatable, and theranostic prodrug for dual-targeted cancer imaging and therapy. J Am Chem Soc (2011) 1.09
Insight into nanoparticle cellular uptake and intracellular targeting. J Control Release (2014) 1.08
Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting. J Drug Deliv (2013) 1.06
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate. Chem Commun (Camb) (2010) 1.04
Coencapsulation of arsenic- and platinum-based drugs for targeted cancer treatment. Angew Chem Int Ed Engl (2009) 1.04
Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis. Arthritis Rheum (2011) 1.03
Assessment of disease activity in rheumatoid arthritis using a novel folate targeted radiopharmaceutical Folatescan. Clin Exp Rheumatol (2009) 1.02
Strategy to prevent drug-related hypersensitivity in folate-targeted hapten immunotherapy of cancer. AAPS J (2009) 1.02
The effect of nanoparticle uptake on cellular behavior: disrupting or enabling functions? Nanotechnol Sci Appl (2012) 1.00
Real time monitoring of biomaterial-mediated inflammatory responses via macrophage-targeting NIR nanoprobes. Biomaterials (2011) 0.98
Bioconjugated pluronic triblock-copolymer micelle-encapsulated quantum dots for targeted imaging of cancer: in vitro and in vivo studies. Theranostics (2012) 0.97
Functional folate receptor alpha is elevated in the blood of ovarian cancer patients. PLoS One (2009) 0.96
Environment-responsive nanophores for therapy and treatment monitoring via molecular MRI quenching. Nat Commun (2014) 0.95
A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity. Arthritis Res Ther (2011) 0.95
Intraoperative imaging in ovarian cancer: fact or fiction? Mol Imaging (2011) 0.94
Self-assembly of natural and synthetic drug amphiphiles into discrete supramolecular nanostructures. Faraday Discuss (2013) 0.94
Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo. J Mater Chem B Mater Biol Med (2013) 0.92
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. Eur J Med Chem (2011) 0.91
A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules. ACS Chem Biol (2010) 0.91
Cucurbit[7]uril containers for targeted delivery of oxaliplatin to cancer cells. Angew Chem Int Ed Engl (2013) 0.91
Folate-targeted docetaxel-lipid-based-nanosuspensions for active-targeted cancer therapy. Int J Nanomedicine (2012) 0.90
The smart targeting of nanoparticles. Curr Pharm Des (2013) 0.89
Enhanced apoptosis of ovarian cancer cells via nanocarrier-mediated codelivery of siRNA and doxorubicin. Int J Nanomedicine (2012) 0.89
Glucan particles for macrophage targeted delivery of nanoparticles. J Drug Deliv (2011) 0.89
Oligonucleotide conjugates for therapeutic applications. Ther Deliv (2013) 0.89
Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells. Adv Funct Mater (2015) 0.88
Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing. Mol Ther Nucleic Acids (2012) 0.88
RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model. Oncotarget (2015) 0.87
Near-infrared fluorescent imaging of metastatic ovarian cancer using folate receptor-targeted high-density lipoprotein nanocarriers. Nanomedicine (Lond) (2012) 0.87
Avidity modulation of folate-targeted multivalent dendrimers for evaluating biophysical models of cancer targeting nanoparticles. ACS Chem Biol (2013) 0.87
Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis. Arthritis Res Ther (2013) 0.87
Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours. Br J Cancer (2009) 0.87
Matrix Metalloproteinase Responsive, Proximity-activated Polymeric Nanoparticles for siRNA Delivery. Adv Funct Mater (2013) 0.87
Nanoparticles for Improving Cancer Diagnosis. Mater Sci Eng R Rep (2013) 0.87
Avidity mechanism of dendrimer-folic acid conjugates. Mol Pharm (2014) 0.86
Application of strain-promoted azide-alkyne cycloaddition and tetrazine ligation to targeted Fc-drug conjugates. Bioconjug Chem (2012) 0.86
Targeted and armed oncolytic adenovirus via chemoselective modification. Bioorg Med Chem Lett (2011) 0.86
Current trends in the use of liposomes for tumor targeting. Nanomedicine (Lond) (2013) 0.86
Effect of an immunotoxin to folate receptor beta on bleomycin-induced experimental pulmonary fibrosis. Clin Exp Immunol (2010) 0.86
Folate receptor-mediated enhanced and specific delivery of far-red light-activatable prodrugs of combretastatin A-4 to FR-positive tumor. Bioconjug Chem (2014) 0.86
Multifunctional core/shell nanoparticles cross-linked polyetherimide-folic acid as efficient Notch-1 siRNA carrier for targeted killing of breast cancer. Sci Rep (2014) 0.85
A photochemical approach for controlled drug release in targeted drug delivery. Bioorg Med Chem (2011) 0.85
Folate receptor-targeted aggregation-enhanced near-IR emitting silica nanoprobe for one-photon in vivo and two-photon ex vivo fluorescence bioimaging. Bioconjug Chem (2011) 0.85
Mechanisms and implications of dual-acting methotrexate in folate-targeted nanotherapeutic delivery. Int J Mol Sci (2015) 0.84
Grand challenge commentary: Synthetic immunology to engineer human immunity. Nat Chem Biol (2010) 0.84
Folate receptor-β constitutes a marker for human proinflammatory monocytes. J Leukoc Biol (2014) 0.84
Dual-targeting pro-apoptotic peptide for programmed cancer cell death via specific mitochondria damage. Sci Rep (2013) 0.84
Inflammatory biomarkers in osteoarthritis. Osteoarthritis Cartilage (2015) 0.84
Prospects in folate receptor-targeted radionuclide therapy. Front Oncol (2013) 0.83
Potential use of folate-appended methyl-β-cyclodextrin as an anticancer agent. Sci Rep (2013) 0.83
Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging. Int J Mol Imaging (2015) 0.82
Targeted dendrimeric anticancer prodrug: a methotrexate-folic acid-poly(amidoamine) conjugate and a novel, rapid, "one pot" synthetic approach. Bioconjug Chem (2010) 0.82
The delivery of therapeutic oligonucleotides. Nucleic Acids Res (2016) 0.82
Development of new folate-based PET radiotracers: preclinical evaluation of ⁶⁸Ga-DOTA-folate conjugates. Eur J Nucl Med Mol Imaging (2010) 0.82
ATRP Synthesis of Sunflower Polymers using Cyclic Multimacroinitiators. ACS Macro Lett (2015) 0.81
Gold nanoparticles and their alternatives for radiation therapy enhancement. Front Chem (2014) 0.81
Optical imaging probes in oncology. Oncotarget (2016) 0.81
Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic. Curr Pharm Des (2013) 0.80
Self-assembled lipid nanomedicines for siRNA tumor targeting. J Biomed Nanotechnol (2009) 0.80
Trojan horses and guided missiles: targeted therapies in the war on arthritis. Nat Rev Rheumatol (2015) 0.80
Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage. Arthritis Res Ther (2014) 0.80
In vivo mouse fluorescence imaging for folate-targeted delivery and release kinetics. Biomed Opt Express (2014) 0.80
One-step instant synthesis of protein-conjugated quantum dots at room temperature. Sci Rep (2013) 0.79
The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment. Int J Nanomedicine (2015) 0.79
Functionalized magnetic iron oxide/alginate core-shell nanoparticles for targeting hyperthermia. Int J Nanomedicine (2015) 0.79
Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of (161)Tb-folate and (177)Lu-folate. EJNMMI Res (2016) 0.79
Ultrabright fluorescent mesoporous silica nanoparticles for prescreening of cervical cancer. Nanomedicine (2013) 0.78
Folate-immunoglobulin G as an anticancer therapeutic antibody. Bioconjug Chem (2010) 0.78
Assessment of folate receptor-β expression in human neoplastic tissues. Oncotarget (2015) 0.78
LHRH-targeted nanogels as a delivery system for cisplatin to ovarian cancer. Mol Pharm (2013) 0.78
Biophysical characterization of a riboflavin-conjugated dendrimer platform for targeted drug delivery. Biomacromolecules (2012) 0.78
Folate-chitosan-gemcitabine core-shell nanoparticles targeted to pancreatic cancer. Chin J Cancer Res (2013) 0.78
Folate-equipped nanolipoplexes mediated efficient gene transfer into human epithelial cells. Int J Mol Sci (2013) 0.78
Targeted delivery of platinum-taxane combination therapy in ovarian cancer. J Control Release (2015) 0.77
Designing polymers with sugar-based advantages for bioactive delivery applications. J Control Release (2015) 0.77
New aspects of gene-silencing for the treatment of cardiovascular diseases. Pharmaceuticals (Basel) (2013) 0.77
Folate receptor α expression and significance in endometrioid endometrium carcinoma and endometrial hyperplasia. Int J Clin Exp Pathol (2015) 0.77
Rational design for multifunctional non-liposomal lipid-based nanocarriers for cancer management: theory to practice. J Nanobiotechnology (2013) 0.77
Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids. Eur J Med Chem (2015) 0.77
Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17. Oncotarget (2016) 0.77
Folate receptor-targeted multimodality imaging of ovarian cancer in a novel syngeneic mouse model. Mol Pharm (2015) 0.77
18 F-click labeling and preclinical evaluation of a new 18 F-folate for PET imaging. EJNMMI Res (2013) 0.76
Design of Nanoparticle-Based Carriers for Targeted Drug Delivery. J Nanomater (2016) 0.76
Small Molecule Ligands For Active Targeting Of TrkC-expressing Tumor Cells. ACS Med Chem Lett (2012) 0.76
Validation of a Janus role of methotrexate-based PEGylated chitosan nanoparticles in vitro. Nanoscale Res Lett (2014) 0.76
Synthesis and activity of a folate peptide camptothecin prodrug. Bioorg Med Chem Lett (2006) 1.12
Detection of Bacillus subtilis spores using peptide-functionalized cantilever arrays. J Am Chem Soc (2006) 1.03
Synthesis and biological analysis of prostate-specific membrane antigen-targeted anticancer prodrugs. J Med Chem (2010) 0.98
Immunomagnetic diffractometry for detection of diagnostic serum markers. J Am Chem Soc (2007) 0.90
Detection of folate binding protein with enhanced sensitivity using a functionalized quartz crystal microbalance sensor. Anal Chem (2006) 0.87
Use of Thromboelastography (TEG) for Detection of New Oral Anticoagulants. Arch Pathol Lab Med (2015) 0.86
Label-free optical detection of anthrax-causing spores. J Am Chem Soc (2007) 0.81
Selective capture and identification of pathogenic bacteria using an immobilized siderophore. Langmuir (2010) 0.79
Two-photon Luminescence Imaging of Bacillus Spores Using Peptide-functionalized Gold Nanorods. Nano Res (2008) 0.78
Synthesis and activity of folate conjugated didemnin B for potential treatment of inflammatory diseases. Bioorg Med Chem Lett (2011) 0.78