Published in Biochem Pharmacol on September 13, 2013
Drug Repurposing Screen Identifies Foxo1-Dependent Angiopoietin-2 Regulation in Sepsis. Crit Care Med (2015) 1.45
Pleiotropic effects of statins: new therapeutic targets in drug design. Naunyn Schmiedebergs Arch Pharmacol (2016) 0.80
Systemic angiopoietin-1/2 dysregulation following cardiopulmonary bypass in adults. Future Sci OA (2017) 0.75
Lovastatin exerts protective effects on endothelial cells via upregulation of PTK2B. Exp Ther Med (2016) 0.75
Mortality after surgery in Europe: a 7 day cohort study. Lancet (2012) 9.96
Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N Engl J Med (2005) 6.32
Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery. JAMA (2007) 6.04
A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery. N Engl J Med (2015) 4.22
European Society of Anaesthesiology Clinical Trials Network. Eur J Anaesthesiol (2011) 3.36
Prospective external validation of a predictive score for postoperative pulmonary complications. Anesthesiology (2014) 3.01
Lack of effectiveness of the pulmonary artery catheter in cardiac surgery. Anesth Analg (2011) 2.83
A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples. Med Microbiol Immunol (2007) 2.64
Hemodynamic monitoring and management in patients undergoing high risk surgery: a survey among North American and European anesthesiologists. Crit Care (2011) 2.59
Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of toll-like receptor 9. Cardiovasc Res (2008) 1.80
Impact of sodium/proton exchanger 3 gene variants on sudden infant death syndrome. J Pediatr (2010) 1.65
Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine: European Perioperative Clinical Outcome (EPCO) definitions: a statement from the ESA-ESICM joint taskforce on perioperative outcome measures. Eur J Anaesthesiol (2015) 1.64
In vivo Toll-like receptor 4 antagonism restores cardiac function during endotoxemia. Shock (2011) 1.60
Utility of a commercially available multiplex real-time PCR assay to detect bacterial and fungal pathogens in febrile neutropenia. J Clin Microbiol (2009) 1.59
2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA). Eur J Anaesthesiol (2014) 1.59
Improved detection of blood stream pathogens by real-time PCR in severe sepsis. Intensive Care Med (2009) 1.51
Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species. Proc Natl Acad Sci U S A (2003) 1.50
Escherichia coli LPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart. Am J Physiol Heart Circ Physiol (2002) 1.48
Development and validation of a score to predict postoperative respiratory failure in a multicentre European cohort: A prospective, observational study. Eur J Anaesthesiol (2015) 1.47
Ultrasound confirmation of central venous catheter position via a right supraclavicular fossa view using a microconvex probe: an observational pilot study. Eur J Anaesthesiol (2015) 1.45
Role of brainstem sodium/proton exchanger 3 for breathing control during chronic acid base imbalance. Am J Respir Crit Care Med (2007) 1.44
Peristaltic pneumatic compression of the legs reduces fluid demand and improves hemodynamic stability during surgery: a randomized, prospective study. Anesthesiology (2011) 1.41
Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia. Shock (2006) 1.39
Extracellular heat shock protein 60, cardiac myocytes, and apoptosis. Circ Res (2009) 1.34
Coronary microembolization: the role of TNF-alpha in contractile dysfunction. J Mol Cell Cardiol (2002) 1.32
Behavioral conditioning of immunosuppression is possible in humans. FASEB J (2002) 1.29
CpG oligonucleotides as adjuvants for vaccines targeting infectious diseases. Adv Drug Deliv Rev (2009) 1.27
Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cells. J Mol Cell Cardiol (2007) 1.26
Comparison of different decontamination methods for reagents to detect low concentrations of bacterial 16S DNA by real-time-PCR. Mol Biotechnol (2002) 1.26
Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis. Crit Care (2008) 1.21
Toll-like receptor 4 deficiency: smaller infarcts, but no gain in function. BMC Physiol (2007) 1.19
Impact of CYP2D6 genotype on postoperative tramadol analgesia. Pain (2003) 1.19
Nuclear factor-kappaB protects the adult cardiac myocyte against ischemia-induced apoptosis in a murine model of acute myocardial infarction. Circulation (2003) 1.18
Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors. J Neurol Neurosurg Psychiatry (2012) 1.15
Mechanical ventilation strategies and inflammatory responses to cardiac surgery: a prospective randomized clinical trial. Intensive Care Med (2005) 1.14
Real-time PCR for detection and differentiation of gram-positive and gram-negative bacteria. J Clin Microbiol (2002) 1.14
Correlation of approximate entropy, bispectral index, and spectral edge frequency 95 (SEF95) with clinical signs of "anesthetic depth" during coadministration of propofol and remifentanil. Anesthesiology (2003) 1.13
Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells. Blood (2002) 1.11
Therapeutic potential of oligonucleotides expressing immunosuppressive TTAGGG motifs. Ann N Y Acad Sci (2005) 1.10
Load-dependent and -independent regulation of proinflammatory cytokine and cytokine receptor gene expression in the adult mammalian heart. Circulation (2002) 1.09
Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome. Proc Natl Acad Sci U S A (2006) 1.08
Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy. J Am Coll Cardiol (2007) 1.07
Spectral entropy and bispectral index as measures of the electroencephalographic effects of sevoflurane. Anesthesiology (2004) 1.06
FDA guidance on prophylactic DNA vaccines: analysis and recommendations. Vaccine (2009) 1.05
Clinical validation of a new thermodilution system for the assessment of cardiac output and volumetric parameters. Crit Care (2012) 1.05
Therapeutic applications and mechanisms underlying the activity of immunosuppressive oligonucleotides. Ann N Y Acad Sci (2009) 1.02
Assessment of cardiac output, intravascular volume status, and extravascular lung water by transpulmonary indicator dilution in critically ill neonates and infants. J Cardiothorac Vasc Anesth (2002) 1.02
CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo. Respir Res (2007) 1.00
Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site. J Cell Biochem (2004) 1.00
Priming with synthetic oligonucleotides attenuates pressure overload-induced inflammation and cardiac hypertrophy in mice. Cardiovasc Res (2012) 0.99
The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis. Anesthesiology (2013) 0.99
Cardiac inflammation and innate immunity in septic shock: is there a role for toll-like receptors? Chest (2002) 0.98
Screening of copy number polymorphisms in human beta-defensin genes using modified real-time quantitative PCR. J Immunol Methods (2005) 0.98
Prone positioning, systemic hemodynamics, hepatic indocyanine green kinetics, and gastric intramucosal energy balance in patients with acute lung injury. Intensive Care Med (2001) 0.98
Toll-like receptor 4 modulates myocardial ischaemia-reperfusion injury: Role of matrix metalloproteinases. Eur J Heart Fail (2006) 0.96
The toll-like receptor 4-antagonist eritoran reduces murine cardiac hypertrophy. Eur J Heart Fail (2011) 0.95
Synthetic oligonucleotides as modulators of inflammation. J Leukoc Biol (2008) 0.94
Comparison between bispectral index and patient state index as measures of the electroencephalographic effects of sevoflurane. Anesthesiology (2008) 0.94
Protection against Pseudomonas aeruginosa pneumonia and sepsis-induced lung injury by overexpression of beta-defensin-2 in rats. Shock (2006) 0.94
Vascular dysfunction following polymicrobial sepsis: role of pattern recognition receptors. PLoS One (2012) 0.93
Real-time polymerase chain-reaction detection of pathogens is feasible to supplement the diagnostic sequence for urinary tract infections. BJU Int (2009) 0.93
Functional significance of inflammatory mediators in a murine model of resuscitated hemorrhagic shock. Am J Physiol Heart Circ Physiol (2005) 0.93
A tumor necrosis factor gene polymorphism influences the inflammatory response after cardiac operation. Ann Thorac Surg (2003) 0.93
Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8. J Allergy Clin Immunol (2009) 0.91
A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study. J Transl Med (2009) 0.91
Global changes in gene expression and synergistic interactions induced by TLR9 and TLR3. Mol Immunol (2009) 0.90
Artifact robustness, inter- and intraindividual baseline stability, and rational EEG parameter selection. Anesthesiology (2002) 0.90
Cerebral haemodynamics and carbon dioxide reactivity during sepsis syndrome. Crit Care (2007) 0.89
Genomic variations and transcriptional regulation of the human mu-opioid receptor gene. Eur J Pain (2006) 0.89
Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation. J Clin Endocrinol Metab (2007) 0.89
Out-of-hospital cardiopulmonary resuscitation with the AutoPulse system: a prospective observational study with a new load-distributing band chest compression device. Resuscitation (2007) 0.88
Rapid qualitative urinary tract infection pathogen identification by SeptiFast real-time PCR. PLoS One (2011) 0.87
Inducibility of the endogenous antibiotic peptide beta-defensin 2 is impaired in patients with severe sepsis. Crit Care (2007) 0.87
Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: prospective observational clinical and cellular studies. Anesthesiology (2013) 0.87
Immunostimulatory CpG oligonucleotides: Effect on gene expression and utility as vaccine adjuvants. Vaccine (2010) 0.86
The heat shock paradox and cardiac myocytes: role of heat shock factor. Shock (2011) 0.86
Rapid and reliable method for cytochrome P450 2D6 genotyping. Clin Chem (2002) 0.86