Published in Development on October 01, 2013
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A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80
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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell (2006) 18.81
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Nanog safeguards pluripotency and mediates germline development. Nature (2007) 13.01
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Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets. Mol Cell Biol (2006) 2.99
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Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor. Mol Cell Proteomics (2007) 2.63
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity. Development (2008) 2.53
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Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation. Mol Cell (2013) 1.86
Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes. Nat Cell Biol (2013) 1.61
Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a. Epigenetics Chromatin (2008) 1.30
The liberation of embryonic stem cells. PLoS Genet (2011) 1.20
STAT3 and Oct-3/4 control histone modification through induction of Eed in embryonic stem cells. J Biol Chem (2008) 1.16
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Functional analysis of the highly conserved exon IV of XIST RNA. Cytogenet Genome Res (2002) 0.90
A primer on using pooled shRNA libraries for functional genomic screens. Acta Biochim Biophys Sin (Shanghai) (2012) 0.87
Comparative high-throughput RNAi screening methodologies in C. elegans and mammalian cells. N Biotechnol (2012) 0.80
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RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. Cell (2012) 2.77
Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells. Curr Biol (2002) 2.64
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat Cell Biol (2010) 2.55
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity. Development (2008) 2.53
Global hypomethylation of the genome in XX embryonic stem cells. Nat Genet (2005) 2.35
The matrix protein hnRNP U is required for chromosomal localization of Xist RNA. Dev Cell (2010) 2.32
SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet (2008) 2.19
Transcription initiation activity sets replication origin efficiency in mammalian cells. PLoS Genet (2009) 2.17
High-resolution analysis of epigenetic changes associated with X inactivation. Genome Res (2009) 2.02
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands. Elife (2012) 1.99
A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin. Mol Cell (2007) 1.52
Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome. Dev Cell (2012) 1.47
Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation. Curr Biol (2002) 1.36
Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells. Cell Cycle (2006) 1.32
Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a. Epigenetics Chromatin (2008) 1.30
Chromatin sampling--an emerging perspective on targeting polycomb repressor proteins. PLoS Genet (2013) 1.23
A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements. PLoS One (2008) 1.23
Heterochromatin on the inactive X chromosome delays replication timing without affecting origin usage. Proc Natl Acad Sci U S A (2004) 1.16
Enox, a novel gene that maps 10 kb upstream of Xist and partially escapes X inactivation. Genomics (2002) 1.15
Attenuated spread of X-inactivation in an X;autosome translocation. Proc Natl Acad Sci U S A (2006) 1.10
Skewing X chromosome choice by modulating sense transcription across the Xist locus. Genes Dev (2003) 1.09
Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells. Development (2011) 1.08
Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells. PLoS One (2007) 1.08
Genes flanking Xist in mouse and human are separated on the X chromosome in American marsupials. Chromosome Res (2007) 1.07
Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol (2013) 1.07
Advances in understanding chromosome silencing by the long non-coding RNA Xist. Philos Trans R Soc Lond B Biol Sci (2013) 1.04
Xist gene regulation at the onset of X inactivation. Curr Opin Genet Dev (2009) 1.02
A scaffold for X chromosome inactivation. Hum Genet (2011) 1.01
Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy. Proc Natl Acad Sci U S A (2014) 1.01
Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes. Mol Cell Biol (2010) 1.00
Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome features. BMC Bioinformatics (2008) 0.96
Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation. Development (2011) 0.95
Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation. Epigenetics Chromatin (2010) 0.94
Xist expression and macroH2A1.2 localisation in mouse primordial and pluripotent embryonic germ cells. Differentiation (2002) 0.85
FGF4 independent derivation of trophoblast stem cells from the common vole. PLoS One (2009) 0.84
Difference between random and imprinted X inactivation in common voles. Chromosoma (2010) 0.83
Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation. PLoS One (2011) 0.82
Structure and expression pattern of Oct4 gene are conserved in vole Microtus rossiaemeridionalis. BMC Genomics (2008) 0.81
SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaks. J Cell Sci (2014) 0.78
Epigenetic memory and parliamentary privilege combine to evoke discussions on inheritance. Development (2012) 0.77
Corrigendum: Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7. Nat Struct Mol Biol (2015) 0.75