Roger A H Adan

Author PubWeight™ 58.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry. Anal Chem 2006 1.71
2 Melanocortin receptor 4 deficiency affects body weight regulation, grooming behavior, and substrate preference in the rat. Obesity (Silver Spring) 2011 1.50
3 Differential effects of recombinant adeno-associated virus-mediated neuropeptide Y overexpression in the hypothalamic paraventricular nucleus and lateral hypothalamus on feeding behavior. J Neurosci 2007 1.09
4 Difference in susceptibility to activity-based anorexia in two inbred strains of mice. Eur Neuropsychopharmacol 2006 1.07
5 Poor cell surface expression of human melanocortin-4 receptor mutations associated with obesity. J Biol Chem 2003 1.07
6 Neurobiology of overeating and obesity: the role of melanocortins and beyond. Eur J Pharmacol 2011 1.05
7 Optimization of adeno-associated viral vector-mediated gene delivery to the hypothalamus. Hum Gene Ther 2010 1.02
8 Neuropsychological weaknesses in anorexia nervosa: set-shifting, central coherence, and decision making in currently ill and recovered women. Int J Eat Disord 2012 1.01
9 Nutritional state affects the expression of the obesity-associated genes Etv5, Faim2, Fto, and Negr1. Obesity (Silver Spring) 2012 0.99
10 Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression. BMC Neurosci 2009 0.98
11 Acute and chronic suppression of the central ghrelin signaling system reveals a role in food anticipatory activity. Eur Neuropsychopharmacol 2011 0.96
12 Leptin treatment in activity-based anorexia. Biol Psychiatry 2005 0.94
13 Peptoid-peptide hybrids as potent novel melanocortin receptor ligands. J Med Chem 2005 0.94
14 Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event. J Mol Endocrinol 2005 0.94
15 Dopamine antagonism inhibits anorectic behavior in an animal model for anorexia nervosa. Eur Neuropsychopharmacol 2008 0.93
16 Olanzapine-induced weight gain: chronic infusion using osmotic minipumps does not result in stable plasma levels due to degradation of olanzapine in solution. Eur J Pharmacol 2008 0.91
17 Ghrelin mediates anticipation to a palatable meal in rats. Obesity (Silver Spring) 2012 0.91
18 Hyperactivity in anorexia nervosa: warming up not just burning-off calories. PLoS One 2012 0.90
19 Sustained NPY overexpression in the PVN results in obesity via temporarily increasing food intake. Obesity (Silver Spring) 2009 0.88
20 Melanocortin-4 receptor gene mutations in a Dutch cohort of obese children. Obesity (Silver Spring) 2010 0.88
21 Morphine withdrawal enhances constitutive μ-opioid receptor activity in the ventral tegmental area. J Neurosci 2012 0.88
22 Improved identification of endogenous peptides from murine nervous tissue by multiplexed peptide extraction methods and multiplexed mass spectrometric analysis. J Proteome Res 2009 0.87
23 Olanzapine reduces physical activity in rats exposed to activity-based anorexia: possible implications for treatment of anorexia nervosa? Biol Psychiatry 2005 0.87
24 Interaction between the spinal melanocortin and opioid systems in a rat model of neuropathic pain. Anesthesiology 2003 0.86
25 Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness. Biochem Pharmacol 2005 0.86
26 An overview on how components of the melanocortin system respond to different high energy diets. Eur J Pharmacol 2011 0.86
27 Inverse agonism at α2A adrenoceptors augments the hypophagic effect of sibutramine in rats. Obesity (Silver Spring) 2011 0.85
28 Dopamine and serotonin release in the nucleus accumbens during starvation-induced hyperactivity. Eur Neuropsychopharmacol 2009 0.85
29 Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat. PLoS One 2011 0.85
30 Induction of brain-region-specific forms of obesity by agouti. J Neurosci 2004 0.85
31 Profiling of diet-induced neuropeptide changes in rat brain by quantitative mass spectrometry. Anal Chem 2013 0.84
32 Hypothalamic neuropeptide expression of juvenile and middle-aged rats after early postnatal food restriction. Endocrinology 2008 0.84
33 Variations in the uncoupling protein-3 gene are associated with specific obesity phenotypes. Eur J Endocrinol 2008 0.84
34 A meta-analysis of circulating BDNF concentrations in anorexia nervosa. World J Biol Psychiatry 2011 0.83
35 AgRP(83-132) and SHU9119 differently affect activity-based anorexia. Eur Neuropsychopharmacol 2005 0.83
36 Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides. Peptides 2003 0.83
37 An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector. BMC Neurosci 2010 0.81
38 Leptin reduces hyperactivity in an animal model for anorexia nervosa via the ventral tegmental area. Eur Neuropsychopharmacol 2010 0.81
39 Towards an animal model of food addiction. Obes Facts 2012 0.81
40 Olanzapine affects locomotor activity and meal size in male rats. Pharmacol Biochem Behav 2010 0.81
41 Olanzapine and sibutramine have opposing effects on the motivation for palatable food. Behav Pharmacol 2012 0.80
42 Polymorphisms in the brain-derived neurotrophic factor gene are not associated with either anorexia nervosa or schizophrenia in Dutch patients. Psychiatr Genet 2005 0.80
43 Mandometer treatment not superior to treatment as usual for anorexia nervosa. Int J Eat Disord 2011 0.80
44 The Val66Met polymorphism of the BDNF gene in anorexia nervosa: new data and a meta-analysis. World J Biol Psychiatry 2011 0.80
45 Limbic substrates of the effects of neuropeptide Y on intake of and motivation for palatable food. Obesity (Silver Spring) 2014 0.80
46 alpha-MSH enhances activity-based anorexia. Peptides 2005 0.80
47 Anticipation of meals during restricted feeding increases activity in the hypothalamus in rats. Eur J Neurosci 2011 0.80
48 To eat or not to eat; regulation by the melanocortin system. Physiol Behav 2006 0.80
49 Synthesis of a novel potent cyclic peptide MC4-ligand by ring-closing metathesis. Bioorg Med Chem 2005 0.79
50 Recombinant adeno-associated viral vectors. Methods Mol Biol 2011 0.79
51 Voluntary access to a warm plate reduces hyperactivity in activity-based anorexia. Physiol Behav 2005 0.79
52 Refinement of behavioural traits in animals for the genetic dissection of eating disorders. Eur J Pharmacol 2003 0.78
53 Dietary factors affect food reward and motivation to eat. Obes Facts 2012 0.78
54 Role of ghrelin in the pathophysiology of eating disorders: implications for pharmacotherapy. CNS Drugs 2012 0.78
55 Longitudinal changes in the physical activity of adolescents with anorexia nervosa and their influence on body composition and leptin serum levels after recovery. PLoS One 2013 0.78
56 Blocking alpha2A adrenoceptors, but not dopamine receptors, augments bupropion-induced hypophagia in rats. Obesity (Silver Spring) 2013 0.78
57 Low control over palatable food intake in rats is associated with habitual behavior and relapse vulnerability: individual differences. PLoS One 2013 0.78
58 Melanocortin MC(4) receptor-mediated feeding and grooming in rodents. Eur J Pharmacol 2013 0.77
59 Multimeric alpha-MSH has increased efficacy to activate the melanocortin MC4 receptor. Eur J Pharmacol 2008 0.77
60 Repeated agouti related peptide (83-132) injections inhibit cocaine-induced locomotor sensitisation, but not via the nucleus accumbens. Eur J Pharmacol 2013 0.77
61 The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol 2003 0.77
62 Animal models of eating disorder traits. Curr Top Behav Neurosci 2011 0.76
63 Mutation analysis of the agouti related protein promoter region and the melanocortin-3 receptor in anorexia nervosa patients. Psychiatr Genet 2005 0.76
64 Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data. Psychiatr Genet 2012 0.76
65 Synthesis of cyclic peptidosulfonamides as scaffolds for MC4 pharmacophoric groups. Bioorg Med Chem Lett 2005 0.76
66 Reduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats. Endocrinology 2005 0.76
67 Both overexpression of agouti-related peptide or neuropeptide Y in the paraventricular nucleus or lateral hypothalamus induce obesity in a neuropeptide- and nucleus specific manner. Eur J Pharmacol 2011 0.76
68 Neuropeptide delivery to the brain: a von Willebrand factor signal peptide to direct neuropeptide secretion. BMC Neurosci 2010 0.75
69 Accelerating sensory recovery after sciatic nerve crush: non-selective versus melanocortin MC4 receptor-selective peptides. Eur J Pharmacol 2004 0.75