Published in Toxins (Basel) on September 24, 2013
Role of miRNA in the regulation of inflammatory genes in staphylococcal enterotoxin B-induced acute inflammatory lung injury and mortality. Toxicol Sci (2015) 0.92
Staphylococcal enterotoxins in the etiopathogenesis of mucosal autoimmunity within the gastrointestinal tract. Toxins (Basel) (2014) 0.86
Staphylococcal enterotoxin B-induced microRNA-155 targets SOCS1 to promote acute inflammatory lung injury. Infect Immun (2014) 0.84
Δ(9) Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells. Br J Pharmacol (2015) 0.82
Toxic shock syndrome toxin-1-mediated toxicity inhibited by neutralizing antibodies late in the course of continual in vivo and in vitro exposure. Toxins (Basel) (2014) 0.82
Sulfasalazine attenuates staphylococcal enterotoxin B-induced immune responses. Toxins (Basel) (2015) 0.80
The Immune System of HIV-Exposed Uninfected Infants. Front Immunol (2016) 0.79
Staphylococcal Superantigens Spark Host-Mediated Danger Signals. Front Immunol (2016) 0.78
Distribution of toxin genes among different spa types and phage types of animal Staphylococcus aureus. Arch Microbiol (2015) 0.76
Enterotoxins: Microbial Proteins and Host Cell Dysregulation. Toxins (Basel) (2016) 0.75
Effects of Traumeel (Tr14) on Exercise-Induced Muscle Damage Response in Healthy Subjects: A Double-Blind RCT. Mediators Inflamm (2016) 0.75
DEBS - a unification theory for dry eye and blepharitis. Clin Ophthalmol (2016) 0.75
Stress-caused anergy of leukocytes towards Staphylococcal enterotoxin B and exposure transcriptome signatures. Genes Immun (2015) 0.75
3,39-Diindolylmethane Ameliorates Staphylococcal Enterotoxin B–Induced Acute Lung Injury through Alterations in the Expression of MicroRNA that Target Apoptosis and Cell-Cycle Arrest in Activated T Cells. J Pharmacol Exp Ther (2016) 0.75
Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology. J Immunol (2017) 0.75
Mini-Osmotic Pump Infusion Model to Investigate the Systemic Effects of Chronic Continuous Exposure to Staphylococcal Superantigen in Mice. Methods Mol Biol (2016) 0.75
FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights. Immunotargets Ther (2017) 0.75
TOR signaling in growth and metabolism. Cell (2006) 35.29
AKT/PKB signaling: navigating downstream. Cell (2007) 31.26
Pattern recognition receptors and inflammation. Cell (2010) 21.05
The staphylococcal enterotoxins and their relatives. Science (1990) 11.99
Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol (2009) 11.76
mTOR signaling at a glance. J Cell Sci (2009) 8.66
Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A (1989) 7.48
T cell activation. Annu Rev Immunol (2009) 7.40
The role of the CD28 receptor during T cell responses to antigen. Annu Rev Immunol (1993) 5.65
The JAK-STAT signaling pathway: input and output integration. J Immunol (2007) 4.92
NF-κB and the link between inflammation and cancer. Immunol Rev (2012) 4.74
Immunoregulatory functions of mTOR inhibition. Nat Rev Immunol (2009) 4.66
The IL-1 family: regulators of immunity. Nat Rev Immunol (2010) 4.65
Toxic shock syndrome and bacterial superantigens: an update. Annu Rev Microbiol (2001) 4.48
p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol (2001) 4.38
T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor. J Exp Med (1992) 4.31
Superantigens and their potential role in human disease. Adv Immunol (1993) 3.88
Immunopharmacology of rapamycin. Annu Rev Immunol (1996) 3.86
Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling. Trends Immunol (2002) 3.64
Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. Physiol Rev (2012) 3.62
Janus kinases in immune cell signaling. Immunol Rev (2009) 3.60
Gram-positive toxic shock syndromes. Lancet Infect Dis (2009) 3.37
Interleukin-2 receptor signaling: at the interface between tolerance and immunity. Immunity (2010) 3.27
The chemokine superfamily revisited. Immunity (2012) 2.83
Trial watch: phase III and submission failures: 2007-2010. Nat Rev Drug Discov (2011) 2.73
Purification and some physicochemical properties of toxic-shock toxin. Biochemistry (1983) 2.65
Toxic shock syndrome toxin 1 as an inducer of human tumor necrosis factors and gamma interferon. J Exp Med (1988) 2.61
Phosphoinositide 3-kinase: diverse roles in immune cell activation. Annu Rev Immunol (2004) 2.59
Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation. Nat Med (2000) 2.55
The bacterial superantigen and superantigen-like proteins. Immunol Rev (2008) 2.44
Bacterial superantigens. Clin Exp Immunol (2003) 2.42
Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med (1992) 2.38
HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med (1990) 2.30
Structural biology of shared cytokine receptors. Annu Rev Immunol (2009) 2.27
Neutrophils cascading their way to inflammation. Trends Immunol (2011) 2.19
Akt-dependent and -independent mechanisms of mTOR regulation in cancer. Cell Signal (2009) 2.11
Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors ClfA and ClfB, the serine-aspartate repeat protein SdrE and protein A. Mol Microbiol (2002) 2.02
Bacterial pyrogenic exotoxins as superantigens. Clin Microbiol Rev (1995) 1.95
Binding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shock. PLoS Biol (2011) 1.93
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis. Nat Med (2005) 1.88
ENHANCEMENT OF BACTERIAL ENDOTOXIN LETHALITY BY STAPHYLOCOCCAL ENTEROTOXIN. J Infect Dis (1964) 1.87
Food poisoning and Staphylococcus aureus enterotoxins. Toxins (Basel) (2010) 1.84
Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro. Nature (1994) 1.79
Toxicity of staphylococcal enterotoxins potentiated by lipopolysaccharide: major histocompatibility complex class II molecule dependency and cytokine release. Infect Immun (1993) 1.69
T cell antigen-receptor signal transduction. Curr Opin Immunol (1999) 1.68
Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B. Immunity (1998) 1.68
Staphylococcal enterotoxin A has two cooperative binding sites on major histocompatibility complex class II. J Exp Med (1995) 1.58
The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells. Nat Immunol (2009) 1.55
Staphylococcal exotoxin activation of T cells. Role of exotoxin-MHC class II binding affinity and class II isotype. J Immunol (1991) 1.50
Transcriptional activation of IL-1 beta and tumor necrosis factor-alpha genes by MHC class II ligands. J Immunol (1991) 1.49
Immune synapses in T-cell activation. Curr Opin Immunol (2006) 1.48
Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases. Arterioscler Thromb Vasc Biol (2012) 1.45
Staphylococcal toxic shock syndrome 2000-2006: epidemiology, clinical features, and molecular characteristics. PLoS One (2011) 1.43
Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock. Infect Immun (1993) 1.42
Different staphylococcal enterotoxins bind preferentially to distinct major histocompatibility complex class II isotypes. Eur J Immunol (1989) 1.39
A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor beta chain and major histocompatibility complex class II. J Exp Med (1998) 1.39
Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice. J Immunol (1994) 1.37
CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. J Exp Med (1992) 1.36
Superantigen and endotoxin synergize in the induction of lethal shock. Eur J Immunol (1997) 1.31
Microbial superantigens: from structure to function. Trends Microbiol (2000) 1.31
Gram-positive bacterial superantigen outside-in signaling causes toxic shock syndrome. FEBS J (2011) 1.29
Superantigen mediated shock: a cytokine release syndrome. Immunobiology (1993) 1.29
Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway. Immunity (2006) 1.26
Subsets of HLA-DR1 molecules defined by SEB and TSST-1 binding. Science (1994) 1.24
Inhibition of bacterial superantigens by peptides and antibodies. Infect Immun (2001) 1.24
Staphylococcal toxins bind to different sites on HLA-DR. J Immunol (1991) 1.21
The mechanism of superantigen-mediated toxic shock: not a simple Th1 cytokine storm. J Immunol (2005) 1.20
Transcytosis of staphylococcal superantigen toxins. J Exp Med (1997) 1.20
Relationship between enterotoxic- and T lymphocyte-stimulating activity of staphylococcal enterotoxin B. J Immunol (1990) 1.20
Differences in potency of intravenous polyspecific immunoglobulin G against streptococcal and staphylococcal superantigens: implications for therapy of toxic shock syndrome. Clin Infect Dis (2004) 1.18
Generation, characterization, and epitope mapping of neutralizing and protective monoclonal antibodies against staphylococcal enterotoxin B-induced lethal shock. J Biol Chem (2011) 1.17
Humanlike immune response of human leukocyte antigen-DR3 transgenic mice to staphylococcal enterotoxins: a novel model for superantigen vaccines. J Infect Dis (2002) 1.17
Toxic shock syndrome toxin-1 induces inositol phospholipid turnover, protein kinase C translocation, and calcium mobilization in human T cells. J Immunol (1988) 1.17
Induction of unresponsiveness and impaired T cell expansion by staphylococcal enterotoxin B in CD28-deficient mice. J Exp Med (1996) 1.16
Protection against lethal toxic shock by targeted disruption of the CD28 gene. J Exp Med (1996) 1.12
Superantigen vaccines: a comparative study of genetically attenuated receptor-binding mutants of staphylococcal enterotoxin A. J Infect Dis (1996) 1.12
Human CD4 and human major histocompatibility complex class II (DQ6) transgenic mice: supersensitivity to superantigen-induced septic shock. Eur J Immunol (1996) 1.12
Immune-mediated side-effects of cytokines in humans. Toxicology (1995) 1.11
In vitro and in vivo evaluation of staphylococcal superantigen peptide antagonists. Infect Immun (2004) 1.11
Role of protein tyrosine phosphorylation in monokine induction by the staphylococcal superantigen toxic shock syndrome toxin-1. J Immunol (1992) 1.11
Lethal synergism between influenza infection and staphylococcal enterotoxin B in mice. J Immunol (1996) 1.09
Superantigen shock in mice with an inapparent viral infection. J Infect Dis (1994) 1.08
Induction of acute inflammatory lung injury by staphylococcal enterotoxin B. J Immunol (1997) 1.07
Induction of acute inflammation in vivo by staphylococcal superantigens. II. Critical role for chemokines, ICAM-1, and TNF-alpha. J Immunol (1998) 1.07
Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B. Infect Immun (2005) 1.06
Doxycycline is anti-inflammatory and inhibits staphylococcal exotoxin-induced cytokines and chemokines. Antimicrob Agents Chemother (2003) 1.05
Cross-reactive antibodies prevent the lethal effects of Staphylococcus aureus superantigens. J Infect Dis (1999) 1.05
Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice. Infect Immun (1995) 1.04
Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1. EMBO J (2007) 1.03
Inhibition of toxic shock by human monoclonal antibodies against staphylococcal enterotoxin B. PLoS One (2010) 1.03
Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor. Mol Ther (2009) 1.03
Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury. Br J Pharmacol (2012) 1.01
Analysis of superantigenic toxin Vbeta T-cell signatures produced during cases of staphylococcal toxic shock syndrome and septic shock. Clin Microbiol Infect (2008) 1.01
T cell activation signals up-regulate p38 mitogen-activated protein kinase activity and induce TNF-alpha production in a manner distinct from LPS activation of monocytes. J Immunol (1999) 1.00
Induction of CC chemokines in human peripheral blood mononuclear cells by staphylococcal exotoxins and its prevention by pentoxifylline. J Leukoc Biol (1999) 1.00
Staphylococcal toxic shock syndrome toxin 1-induced tumor necrosis factor alpha and interleukin-1 beta secretion by human peripheral blood monocytes and T lymphocytes is differentially suppressed by protein kinase inhibitors. Infect Immun (1992) 1.00
Toxic shock syndrome toxin-1-induced death is prevented by CTLA4Ig. J Immunol (1996) 0.99
Potent neutralization of staphylococcal enterotoxin B by synergistic action of chimeric antibodies. Infect Immun (2010) 0.99
Functional analysis of the TCR binding domain of toxic shock syndrome toxin-1 predicts further diversity in MHC class II/superantigen/TCR ternary complexes. J Immunol (2003) 0.98
Evidence for the involvement of bacterial superantigens in psoriasis, atopic dermatitis, and Kawasaki syndrome. FEMS Microbiol Lett (2000) 0.98