Published in ACS Synth Biol on October 04, 2013
Illuminating cell signalling with optogenetic tools. Nat Rev Mol Cell Biol (2014) 1.46
Synthetic biology in mammalian cells: next generation research tools and therapeutics. Nat Rev Mol Cell Biol (2014) 1.41
Optical control of cell signaling by single-chain photoswitchable kinases. Science (2017) 1.41
Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth. PLoS One (2014) 1.07
Optogenetic approaches to cell migration and beyond. Curr Opin Cell Biol (2014) 1.06
Optogenetic control of intracellular signaling pathways. Trends Biotechnol (2014) 1.01
Photochemistry of flavoprotein light sensors. Nat Chem Biol (2014) 1.00
Natural photoreceptors as a source of fluorescent proteins, biosensors, and optogenetic tools. Annu Rev Biochem (2015) 0.92
Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions. Development (2014) 0.92
Photoreceptor engineering. Front Mol Biosci (2015) 0.83
Molecular mechanisms underlying alcohol-drinking behaviours. Nat Rev Neurosci (2016) 0.83
Subcellular optogenetics - controlling signaling and single-cell behavior. J Cell Sci (2014) 0.82
An open-hardware platform for optogenetics and photobiology. Sci Rep (2016) 0.82
Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep (2016) 0.77
Lighting up FGFR signaling. Chem Biol (2014) 0.77
The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. ACS Synth Biol (2015) 0.76
Tools for controlling protein interactions using light. Curr Protoc Cell Biol (2014) 0.76
Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions. Sci Rep (2016) 0.75
Modular engineering of cellular signaling proteins and networks. Curr Opin Struct Biol (2016) 0.75
Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases. Proteomes (2015) 0.75
Optical control of biological processes by light-switchable proteins. Wiley Interdiscip Rev Dev Biol (2015) 0.75
Mimicking transient activation of protein kinases in living cells. Proc Natl Acad Sci U S A (2016) 0.75
Reversible optogenetic control of kinase activity during differentiation and embryonic development. Development (2016) 0.75
Targeting protein function: the expanding toolkit for conditional disruption. Biochem J (2016) 0.75
Modulation of cyclic nucleotide-mediated cellular signaling and gene expression using photoactivated adenylyl cyclase as an optogenetic tool. Sci Rep (2017) 0.75
Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun (2017) 0.75
An engineered epigenetic transgene switch in mammalian cells. Nat Biotechnol (2004) 3.02
Drug-sensing hydrogels for the inducible release of biopharmaceuticals. Nat Mater (2008) 2.23
Synthetic two-way communication between mammalian cells. Nat Biotechnol (2012) 1.78
An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies. Chem Biol (2004) 1.31
A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells. Nucleic Acids Res (2013) 1.22
Multi-chromatic control of mammalian gene expression and signaling. Nucleic Acids Res (2013) 1.17
Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1. J Proteomics (2011) 1.11
Artificial regulatory networks and cascades for discrete multilevel transgene control in mammalian cells. Biotechnol Bioeng (2003) 1.04
Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin. Proc Natl Acad Sci U S A (2009) 1.03
The food additive vanillic acid controls transgene expression in mammalian cells and mice. Nucleic Acids Res (2011) 0.99
Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization. J Biol Chem (2005) 0.98
Characterization of a putative phosphorylation switch: adaptation of SPOT synthesis to analyze PDZ domain regulation mechanisms. Chembiochem (2007) 0.97
CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation. J Biol Chem (2005) 0.97
Synthesis of phycocyanobilin in mammalian cells. Chem Commun (Camb) (2013) 0.97
A short hairpin DNA analogous to miR-125b inhibits C-Raf expression, proliferation, and survival of breast cancer cells. Mol Cancer Res (2009) 0.96
Optogenetic tools for mammalian systems. Mol Biosyst (2013) 0.94
Bacterial signaling systems as platforms for rational design of new generations of biosensors. Curr Opin Biotechnol (2012) 0.93
Therapeutic protein transduction of mammalian cells and mice by nucleic acid-free lentiviral nanoparticles. Nucleic Acids Res (2006) 0.92
A quantitative ratiometric sensor for time-resolved analysis of auxin dynamics. Sci Rep (2013) 0.92
Enhanced plant tolerance to iron starvation by functional substitution of chloroplast ferredoxin with a bacterial flavodoxin. Proc Natl Acad Sci U S A (2007) 0.91
An engineered L-arginine sensor of Chlamydia pneumoniae enables arginine-adjustable transcription control in mammalian cells and mice. Nucleic Acids Res (2007) 0.90
Broad-spectrum protein biosensors for class-specific detection of antibiotics. Biotechnol Bioeng (2005) 0.89
Positioning, displacement, and localization of cells using ultrasonic forces. Biotechnol Bioeng (2005) 0.88
Optogenetic control of signaling in mammalian cells. Biotechnol J (2014) 0.88
A versatile approach to engineering biomolecule-presenting cellular microenvironments. Adv Healthc Mater (2012) 0.86
A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1. Nucleic Acids Res (2005) 0.86
De novo design and construction of an inducible gene expression system in mammalian cells. Methods Enzymol (2011) 0.86
Synthesis and characterization of PEG-based drug-responsive biohybrid hydrogels. Macromol Rapid Commun (2012) 0.85
c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site. Mol Cell Biol (2007) 0.85
Optogenetics for gene expression in mammalian cells. Biol Chem (2015) 0.85
c-Src is a PDZ interaction partner and substrate of the E3 ubiquitin ligase Ligand-of-Numb protein X1. FEBS Lett (2007) 0.84
Synthetic mammalian gene networks as a blueprint for the design of interactive biohybrid materials. Chem Soc Rev (2011) 0.84
New-generation multicistronic expression platform: pTRIDENT vectors containing size-optimized IRES elements enable homing endonuclease-based cistron swapping into lentiviral expression vectors. Biotechnol Bioeng (2004) 0.84
CNK1 promotes invasion of cancer cells through NF-kappaB-dependent signaling. Mol Cancer Res (2010) 0.83
Focal adhesion kinase (FAK) perspectives in mechanobiology: implications for cell behaviour. Cell Tissue Res (2014) 0.83
Rewiring and dosing of systems modules as a design approach for synthetic mammalian signaling networks. Mol Biosyst (2012) 0.83
A biohybrid hydrogel for the urate-responsive release of urate oxidase. J Control Release (2013) 0.82
Role of AF6 protein in cell-to-cell spread of Herpes simplex virus 1. FEBS Lett (2007) 0.81
Plant and bacterial systems biology as platform for plant synthetic bio(techno)logy. J Biotechnol (2012) 0.81
CNK1 and other scaffolds for Akt/FoxO signaling. Biochim Biophys Acta (2011) 0.81
Molecular switches in animal cells. FEBS Lett (2012) 0.80
Modularized CRISPR/dCas9 effector toolkit for target-specific gene regulation. ACS Synth Biol (2014) 0.80
A red light-controlled synthetic gene expression switch for plant systems. Mol Biosyst (2014) 0.80
Therapeutic synthetic gene networks. Curr Opin Biotechnol (2012) 0.79
Increasing the dynamic control space of mammalian transcription devices by combinatorial assembly of homologous regulatory elements from different bacterial species. Metab Eng (2012) 0.78
Building synthetic cell systems from the ground up. Curr Opin Biotechnol (2012) 0.78
Synthetic biology for mammalian cell technology and materials sciences. Biotechnol Adv (2012) 0.78
Orthogonal optogenetic triple-gene control in Mammalian cells. ACS Synth Biol (2014) 0.78
Design and construction of synthetic gene networks in mammalian cells. Methods Mol Biol (2012) 0.78
A novel generic dipstick-based technology for rapid and precise detection of tetracycline, streptogramin and macrolide antibiotics in food samples. J Biotechnol (2006) 0.77
Design, synthesis, and application of stimulus-sensing biohybrid hydrogels. Macromol Rapid Commun (2013) 0.77
Modular poly(ethylene glycol) matrices for the controlled 3D-localized osteogenic differentiation of mesenchymal stem cells. Adv Healthc Mater (2014) 0.77
Novel macrolide-adjustable bidirectional expression modules for coordinated expression of two different transgenes in mice. J Gene Med (2003) 0.77
Synthesis and characterization of a stimulus-responsive L-ornithine-degrading hydrogel. J Control Release (2012) 0.77
Pharmacologically triggered hydrogel for scheduling hepatitis B vaccine administration. Sci Rep (2013) 0.77
RIP2 mediates LPS-induced p38 and IkappaBalpha signaling including IL-12 p40 expression in human monocyte-derived dendritic cells. Eur J Immunol (2007) 0.76
A gas-inducible expression system in HEK.EBNA cells applied to controlled proliferation studies by expression of p27(Kip1). Biotechnol Bioeng (2007) 0.76
The scaffold protein CNK1 interacts with the angiotensin II type 2 receptor. Biochem Biophys Res Commun (2005) 0.76
Evaluation of bicinchoninic acid as a ligand for copper(I)-catalyzed azide-alkyne bioconjugations. Org Biomol Chem (2012) 0.76
Synthetic biology: programming cells for biomedical applications. Perspect Biol Med (2012) 0.76
Pharmacologically controlled protein switch for ON-OFF regulation of growth factor activity. Sci Rep (2013) 0.75
Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions. ChemMedChem (2014) 0.75
Simultaneous positioning of cells into two-dimensional arrays using ultrasound. Biotechnol Bioeng (2007) 0.75
Transcription factor sensor system for parallel quantification of metabolites on-chip. Anal Chem (2014) 0.75
A generic strategy for pharmacological caging of growth factors for tissue engineering. Chem Commun (Camb) (2013) 0.75
Microfluidic synthesis of pharmacologically responsive supramolecular biohybrid microgels. Macromol Biosci (2014) 0.75
Correction to Transcription Factor Sensor System for Parallel Quantification of Metabolites On-Chip. Anal Chem (2015) 0.75
A general strategy for the production of difficult-to-express inducer-dependent bacterial repressor proteins in Escherichia coli. Protein Expr Purif (2009) 0.75
Label-Free SnO<sub>2</sub> Nanowire FET Biosensor for Protein Detection. Nanotechnology (2017) 0.75
Synthetic biology in the analysis and engineering of signaling processes. Integr Biol (Camb) (2009) 0.75
Synthetic gene networks as blueprint for smart hydrogels. Methods Mol Biol (2012) 0.75
A chemical switch for controlling viral infectivity. Chem Commun (Camb) (2014) 0.75
Detection of real-time dynamics of drug-target interactions by ultralong nanowalls. Lab Chip (2013) 0.75
Pharmacologically tunable polyethylene-glycol-based cell growth substrate. Acta Biomater (2013) 0.75