Gen Sheng Wu

Author PubWeight™ 34.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects. Sci Transl Med 2013 2.06
2 Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells. Cell Cycle 2009 1.80
3 DR5 knockout mice are compromised in radiation-induced apoptosis. Mol Cell Biol 2005 1.55
4 ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells. Cancer Res 2007 1.52
5 Stochastic cancer progression driven by non-clonal chromosome aberrations. J Cell Physiol 2006 1.37
6 Role of the Akt/mTOR survival pathway in cisplatin resistance in ovarian cancer cells. Biochem Biophys Res Commun 2010 1.37
7 Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res 2006 1.35
8 TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death. Cancer Biol Ther 2008 1.34
9 The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death. Cancer Res 2006 1.23
10 The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation. J Biol Chem 2003 1.20
11 Bim protein degradation contributes to cisplatin resistance. J Biol Chem 2011 1.13
12 Cisplatin resistance associated with PARP hyperactivation. Cancer Res 2013 1.11
13 The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment. Cancer Metastasis Rev 2010 1.09
14 Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell death. Cancer Biol Ther 2008 1.08
15 Activation of the Akt survival pathway contributes to TRAIL resistance in cancer cells. PLoS One 2010 1.08
16 Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. Cancer Res 2007 1.06
17 Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells. Mol Cancer Ther 2002 1.04
18 Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study. Cancer Res 2008 0.98
19 Sp1-mediated TRAIL induction in chemosensitization. Cancer Res 2008 0.94
20 Mitogen activated protein kinase phosphatases and cancer. Cancer Biol Ther 2010 0.93
21 Post-translational regulation of mitogen-activated protein kinase phosphatase-2 (MKP-2) by ERK. Cell Cycle 2010 0.92
22 Induction of apoptosis by the new anticancer drug XK469 in human ovarian cancer cell lines. Oncogene 2002 0.92
23 Mitotic cell death by chromosome fragmentation. Cancer Res 2007 0.91
24 Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy. Cancer Res 2006 0.86
25 Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. J Biol Chem 2013 0.83
26 p53 Transactivates the phosphatase MKP1 through both intronic and exonic p53 responsive elements. Cancer Biol Ther 2004 0.83
27 Cullin-3 protein expression levels correlate with breast cancer progression. Cancer Biol Ther 2012 0.81
28 Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity. Oncotarget 2014 0.80
29 The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling. Cell Cycle 2014 0.79
30 High level of mitogen-activated protein kinase phosphatase-1 expression is associated with cisplatin resistance in osteosarcoma. Pediatr Blood Cancer 2008 0.79
31 Expression profile of SIX family members correlates with clinic-pathological features and prognosis of breast cancer: A systematic review and meta-analysis. Medicine (Baltimore) 2016 0.78
32 Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA. Int J Cancer 2012 0.75