1
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Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects.
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Sci Transl Med
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2013
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2.06
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2
|
Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells.
|
Cell Cycle
|
2009
|
1.80
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3
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DR5 knockout mice are compromised in radiation-induced apoptosis.
|
Mol Cell Biol
|
2005
|
1.55
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4
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ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells.
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Cancer Res
|
2007
|
1.52
|
5
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Stochastic cancer progression driven by non-clonal chromosome aberrations.
|
J Cell Physiol
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2006
|
1.37
|
6
|
Role of the Akt/mTOR survival pathway in cisplatin resistance in ovarian cancer cells.
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Biochem Biophys Res Commun
|
2010
|
1.37
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7
|
Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance.
|
Cancer Res
|
2006
|
1.35
|
8
|
TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death.
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Cancer Biol Ther
|
2008
|
1.34
|
9
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The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death.
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Cancer Res
|
2006
|
1.23
|
10
|
The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation.
|
J Biol Chem
|
2003
|
1.20
|
11
|
Bim protein degradation contributes to cisplatin resistance.
|
J Biol Chem
|
2011
|
1.13
|
12
|
Cisplatin resistance associated with PARP hyperactivation.
|
Cancer Res
|
2013
|
1.11
|
13
|
The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment.
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Cancer Metastasis Rev
|
2010
|
1.09
|
14
|
Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell death.
|
Cancer Biol Ther
|
2008
|
1.08
|
15
|
Activation of the Akt survival pathway contributes to TRAIL resistance in cancer cells.
|
PLoS One
|
2010
|
1.08
|
16
|
Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin.
|
Cancer Res
|
2007
|
1.06
|
17
|
Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
|
Mol Cancer Ther
|
2002
|
1.04
|
18
|
Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study.
|
Cancer Res
|
2008
|
0.98
|
19
|
Sp1-mediated TRAIL induction in chemosensitization.
|
Cancer Res
|
2008
|
0.94
|
20
|
Mitogen activated protein kinase phosphatases and cancer.
|
Cancer Biol Ther
|
2010
|
0.93
|
21
|
Post-translational regulation of mitogen-activated protein kinase phosphatase-2 (MKP-2) by ERK.
|
Cell Cycle
|
2010
|
0.92
|
22
|
Induction of apoptosis by the new anticancer drug XK469 in human ovarian cancer cell lines.
|
Oncogene
|
2002
|
0.92
|
23
|
Mitotic cell death by chromosome fragmentation.
|
Cancer Res
|
2007
|
0.91
|
24
|
Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy.
|
Cancer Res
|
2006
|
0.86
|
25
|
Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis.
|
J Biol Chem
|
2013
|
0.83
|
26
|
p53 Transactivates the phosphatase MKP1 through both intronic and exonic p53 responsive elements.
|
Cancer Biol Ther
|
2004
|
0.83
|
27
|
Cullin-3 protein expression levels correlate with breast cancer progression.
|
Cancer Biol Ther
|
2012
|
0.81
|
28
|
Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity.
|
Oncotarget
|
2014
|
0.80
|
29
|
The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling.
|
Cell Cycle
|
2014
|
0.79
|
30
|
High level of mitogen-activated protein kinase phosphatase-1 expression is associated with cisplatin resistance in osteosarcoma.
|
Pediatr Blood Cancer
|
2008
|
0.79
|
31
|
Expression profile of SIX family members correlates with clinic-pathological features and prognosis of breast cancer: A systematic review and meta-analysis.
|
Medicine (Baltimore)
|
2016
|
0.78
|
32
|
Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA.
|
Int J Cancer
|
2012
|
0.75
|