Geoffrey W G Sharp

Author PubWeight™ 22.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Glucose-stimulated signaling pathways in biphasic insulin secretion. Diabetes Metab Res Rev 2002 1.96
2 Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion. Diabetes 2002 1.47
3 Stimulation of insulin release by glucose is associated with an increase in the number of docked granules in the beta-cells of rat pancreatic islets. Diabetes 2004 1.16
4 Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion. Am J Physiol Cell Physiol 2004 1.00
5 Noradrenaline inhibits exocytosis via the G protein βγ subunit and refilling of the readily releasable granule pool via the α(i1/2) subunit. J Physiol 2010 0.98
6 CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor. J Biol Chem 2013 0.94
7 Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release. Biochem J 2013 0.93
8 Switch to anaerobic glucose metabolism with NADH accumulation in the beta-cell model of mitochondrial diabetes. Characteristics of betaHC9 cells deficient in mitochondrial DNA transcription. J Biol Chem 2002 0.90
9 Evolving insights regarding mechanisms for the inhibition of insulin release by norepinephrine and heterotrimeric G proteins. Am J Physiol Cell Physiol 2012 0.90
10 Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH. Am J Physiol Endocrinol Metab 2003 0.89
11 A link between Cdc42 and syntaxin is involved in mastoparan-stimulated insulin release. Biochemistry 2002 0.89
12 Protein acylation in the inhibition of insulin secretion by norepinephrine, somatostatin, galanin, and PGE2. Am J Physiol Endocrinol Metab 2003 0.86
13 Anaplerotic input is sufficient to induce time-dependent potentiation of insulin release in rat pancreatic islets. Am J Physiol Endocrinol Metab 2004 0.84
14 Inhibition of insulin secretion by cerulenin might be due to impaired glucose metabolism. Diabetes Metab Res Rev 2007 0.84
15 Intracellular pH plays a critical role in glucose-induced time-dependent potentiation of insulin release in rat islets. Diabetes 2002 0.83
16 Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel. J Biol Chem 2007 0.83
17 The effects of cerulenin, an inhibitor of protein acylation, on the two phases of glucose-stimulated insulin secretion. Diabetes 2002 0.83
18 Inhibitory role of Src family tyrosine kinases on Ca2+-dependent insulin release. Am J Physiol Endocrinol Metab 2006 0.82
19 Stimulation of insulin secretion by denatonium, one of the most bitter-tasting substances known. Diabetes 2003 0.82
20 Hormonal inhibition of endocytosis: novel roles for noradrenaline and G protein G(z). J Physiol 2010 0.80
21 Massive augmentation of stimulated insulin secretion induced by fatty acid-free BSA in rat pancreatic islets. Diabetes 2004 0.80
22 The inhibitors of protein acylation, cerulenin and tunicamycin, increase voltage-dependent Ca(2+) currents in the insulin-secreting INS 832/13 cell. Biochem Pharmacol 2007 0.79
23 Hyposmotic shock stimulates insulin secretion by two distinct mechanisms. Studies with the betaHC9 cell. Am J Physiol Endocrinol Metab 2002 0.76
24 Glucose stimulation of protein acylation in the pancreatic β-cell. Life Sci 2010 0.75