Substrate specificity of phospholipid/Ca2+-dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein.

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Published in J Biol Chem on September 25, 1985

Authors

R S Turner, B E Kemp, H D Su, J F Kuo

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Parathyroid hormone-related protein purified from a human lung cancer cell line. Proc Natl Acad Sci U S A (1987) 3.06

Cyclic nucleotide-dependent protein kinases. VI. Isolation and partial purification of a protein kinase activated by guanosine 3',5'-monophosphate. J Biol Chem (1970) 2.89

An adenosine 3',5'-monophosphate-dependent protein kinase from Escherichia coli. J Biol Chem (1969) 2.86

Structural basis of autoregulation of phenylalanine hydroxylase. Nat Struct Biol (1999) 2.67

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Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization. Biochem J (2001) 1.69

Substrate specificity of the cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1975) 1.68

Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle. Proc Natl Acad Sci U S A (1972) 1.66

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Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation. Eur J Biochem (1990) 1.47

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Giant protein kinases: domain interactions and structural basis of autoregulation. EMBO J (1996) 1.24

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