Published in Cancer Cell on October 14, 2013
BRCAness revisited. Nat Rev Cancer (2016) 1.38
Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage. Cancer Res (2015) 0.95
Wip1 phosphatase in breast cancer. Oncogene (2014) 0.83
The catalytic role of the M2 metal ion in PP2Cα. Sci Rep (2015) 0.79
Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, MethylRO. Stem Cell Reports (2014) 0.78
The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28. J Biol Chem (2015) 0.76
De Novo Truncating Mutations in the Last and Penultimate Exons of PPM1D Cause an Intellectual Disability Syndrome. Am J Hum Genet (2017) 0.75
The BARD1/HP1 interaction: Another clue to heterochromatin involvement in homologous recombination. Mol Cell Oncol (2015) 0.75
Epigenetics: WIP1 creates hush and havoc. Nat Rev Cancer (2013) 0.75
The Epithelial-to-Mesenchymal Transition (EMT), a Particular Case. Mol Cell Oncol (2014) 0.75
Wiping DNA methylation: Wip1 regulates genomic fluidity on cancer. Cancer Cell (2013) 0.75
Deficiency of the tumor promoter gene wip1 induces insulin resistance. Mol Endocrinol (2015) 0.75
Role of wild-type p53-induced phosphatase 1 in cancer. Oncol Lett (2017) 0.75
Tol2 transposon-mediated enhancer trap to identify developmentally regulated zebrafish genes in vivo. Dev Dyn (2004) 2.97
Wip1 phosphatase modulates ATM-dependent signaling pathways. Mol Cell (2006) 2.39
Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint. Cell Cycle (2003) 2.10
Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53. Cancer Res (2002) 1.71
Apoptosis differently affects lineage tracing of Lgr5 and Bmi1 intestinal stem cell populations. Cell Stem Cell (2013) 1.66
Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase. J Exp Med (2006) 1.53
WIP1 phosphatase at the crossroads of cancer and aging. Trends Biochem Sci (2009) 1.52
Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control. Mol Cell Biol (2002) 1.46
p38MAPK controls expression of multiple cell cycle inhibitors and islet proliferation with advancing age. Dev Cell (2009) 1.40
Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine. Cell Stem Cell (2007) 1.37
Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase. Proc Natl Acad Sci U S A (2001) 1.36
Zebrafish transgenic Enhancer TRAP line database (ZETRAP). BMC Dev Biol (2006) 1.35
Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response. Cancer Res (2010) 1.34
WIP1 phosphatase is a negative regulator of NF-kappaB signalling. Nat Cell Biol (2009) 1.30
Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery. Genes Dev (2013) 1.27
Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. J Clin Invest (2015) 1.21
Genome-wide analysis of Tol2 transposon reintegration in zebrafish. BMC Genomics (2009) 1.20
Wip1-dependent regulation of autophagy, obesity, and atherosclerosis. Cell Metab (2012) 1.19
An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening. Dis Model Mech (2011) 1.17
Cytokine-driven cell cycling is mediated through Cdc25A. J Cell Biol (2005) 1.15
A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish. Dis Model Mech (2011) 1.13
Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio. Gene (2005) 1.12
High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair. Am J Physiol Renal Physiol (2003) 1.12
Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis. Cancer Biol Ther (2005) 1.09
Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep (2013) 1.08
Wip1-dependent signaling pathways in health and diseases. Prog Mol Biol Transl Sci (2012) 1.08
Wnt signalling mediated by Tbx2b regulates cell migration during formation of the neural plate. Development (2005) 1.01
Wip1 regulates the generation of new neural cells in the adult olfactory bulb through p53-dependent cell cycle control. Stem Cells (2009) 0.97
Inhibition of the ATR/Chk1 pathway induces a p38-dependent S-phase delay in mouse embryonic stem cells. Cell Cycle (2005) 0.97
A subtle change in p38 MAPK activity is sufficient to suppress in vivo tumorigenesis. Cell Cycle (2005) 0.96
Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors. Proc Natl Acad Sci U S A (2012) 0.96
Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents. Proc Natl Acad Sci U S A (2011) 0.95
Hormone-sensing cells require Wip1 for paracrine stimulation in normal and premalignant mammary epithelium. Breast Cancer Res (2013) 0.90
Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J Clin Invest (2014) 0.89
Genetic variants and mutations of PPM1D control the response to DNA damage. Cell Cycle (2013) 0.86
EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation. Proc Natl Acad Sci U S A (2013) 0.86
Tumor susceptibility and apoptosis defect in a mouse strain expressing a human p53 transgene. Cancer Res (2006) 0.86
Heterochromatin establishment at pericentromeres depends on nuclear position. Genes Dev (2013) 0.83
Generation of oocyte-specifically expressed cre transgenic zebrafish for female germline excision of loxP-flanked transgene. Dev Dyn (2008) 0.83
Wip1 phosphatase positively modulates dendritic spine morphology and memory processes through the p38MAPK signaling pathway. Cell Adh Migr (2012) 0.83
Expression of a novel zebrafish zinc finger gene, gli2b, is affected in Hedgehog and Notch signaling related mutants during embryonic development. Dev Dyn (2005) 0.81
Cre/loxP-regulated transgenic zebrafish model for neural progenitor-specific oncogenic Kras expression. Cancer Sci (2009) 0.81
Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish. Biol Open (2013) 0.80
Zebrafish atonal homologue zath3 is expressed during neurogenesis in embryonic development. Dev Dyn (2003) 0.80
Cdc25A serine 123 phosphorylation couples centrosome duplication with DNA replication and regulates tumorigenesis. Mol Cell Biol (2008) 0.79
One step forward: the use of transgenic zebrafish tumor model in drug screens. Birth Defects Res C Embryo Today (2011) 0.78
WIP-ing out atherosclerosis with autophagy. Autophagy (2012) 0.78
Transposable elements in fish functional genomics: technical challenges and perspectives. Genome Biol (2007) 0.77
PPM1H--new kid on the block. Cancer Biol Ther (2008) 0.75
Wip1 Controls Global Heterochromatin Silencing via ATM/BRCA1-Dependent DNA Methylation. Cancer Cell (2016) 0.75