Published in J Am Chem Soc on November 07, 2013
Channel-forming bacterial toxins in biosensing and macromolecule delivery. Toxins (Basel) (2014) 0.77
Validation of a Janus role of methotrexate-based PEGylated chitosan nanoparticles in vitro. Nanoscale Res Lett (2014) 0.76
Clostridial C3 Toxins Target Monocytes/Macrophages and Modulate Their Functions. Front Immunol (2015) 0.75
Lysine methylation as a routine rescue strategy for protein crystallization. Structure (2006) 3.14
Changes and regulation of the C5a receptor on neutrophils during septic shock in humans. J Immunol (2013) 1.57
Cellular uptake of Clostridium difficile toxin B. Translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells. J Biol Chem (2003) 1.45
Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. J Virol (2011) 1.42
Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept. Proc Natl Acad Sci U S A (2006) 1.41
Erythropoietin (EPO): EPO-receptor signaling improves early endochondral ossification and mechanical strength in fracture healing. Life Sci (2006) 1.40
Structure and action of the binary C2 toxin from Clostridium botulinum. J Mol Biol (2006) 1.20
The host cell chaperone Hsp90 is essential for translocation of the binary Clostridium botulinum C2 toxin into the cytosol. J Biol Chem (2003) 1.19
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic Acids Res (2010) 1.19
An aqueous route to multicolor photoluminescent carbon dots using silica spheres as carriers. Angew Chem Int Ed Engl (2009) 1.14
Progress in solid oxide fuel cells with nickel-based anodes operating on methane and related fuels. Chem Rev (2013) 1.13
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses. Nat Nanotechnol (2013) 1.12
Comparative analysis of viscosity of complex liquids and cytoplasm of mammalian cells at the nanoscale. Nano Lett (2011) 1.12
Clostridium perfringens epsilon toxin: a malevolent molecule for animals and man? Toxins (Basel) (2013) 1.08
Difference in the cytotoxic effects of toxin B from Clostridium difficile strain VPI 10463 and toxin B from variant Clostridium difficile strain 1470. Infect Immun (2006) 1.07
Endothelial Rho signaling is required for monocyte transendothelial migration. FEBS Lett (2002) 1.05
Membrane translocation of binary actin-ADP-ribosylating toxins from Clostridium difficile and Clostridium perfringens is facilitated by cyclophilin A and Hsp90. Infect Immun (2011) 1.05
Bacterial community structure of a pesticide-contaminated site and assessment of changes induced in community structure during bioremediation. FEMS Microbiol Ecol (2006) 1.03
Clostridium botulinum C2 toxin: low pH-induced pore formation is required for translocation of the enzyme component C2I into the cytosol of host cells. J Biol Chem (2003) 1.02
Homology model-based virtual screening for GPCR ligands using docking and target-biased scoring. J Chem Inf Model (2008) 1.01
Surface topographies of glaucoma drainage devices and their influence on human tenon fibroblast adhesion. Invest Ophthalmol Vis Sci (2010) 1.00
Actin filaments are involved in the maintenance of Golgi cisternae morphology and intra-Golgi pH. Cell Motil Cytoskeleton (2006) 0.99
Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen. Cell Microbiol (2010) 0.98
Positive and negative modulation of group I metabotropic glutamate receptors. J Med Chem (2008) 0.98
Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells. Cell Microbiol (2009) 0.97
Predicting compound selectivity by self-organizing maps: cross-activities of metabotropic glutamate receptor antagonists. ChemMedChem (2006) 0.97
Salmonella enterica SpvB ADP-ribosylates actin at position arginine-177-characterization of the catalytic domain within the SpvB protein and a comparison to binary clostridial actin-ADP-ribosylating toxins. Biochemistry (2006) 0.96
Towards highly fluorescent and water-soluble perylene dyes. Chemistry (2004) 0.96
Open abdomen treatment following endovascular repair of ruptured abdominal aortic aneurysms. J Vasc Surg (2009) 0.95
ADP-ribosylation of actin by the Clostridium botulinum C2 toxin in mammalian cells results in delayed caspase-dependent apoptotic cell death. Infect Immun (2008) 0.95
Antibunching in the emission of a single tetrachromophoric dendritic system. J Am Chem Soc (2002) 0.95
Channel formation by the binding component of Clostridium botulinum C2 toxin: glutamate 307 of C2II affects channel properties in vitro and pH-dependent C2I translocation in vivo. Biochemistry (2003) 0.95
Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms. Cell Microbiol (2010) 0.95
Application of the specular and diffuse reflection analysis for in vitro diagnostics of dental erosion: correlation with enamel softening, roughness, and calcium release. J Biomed Opt (2011) 0.93
Comparison of 2 surgical approaches for volar locking plate osteosynthesis of the distal radius. J Hand Surg Am (2008) 0.93
Cellular uptake of Clostridium botulinum C2 toxin: membrane translocation of a fusion toxin requires unfolding of its dihydrofolate reductase domain. Biochemistry (2003) 0.93
Development of a stable closed femoral fracture model in mice. J Surg Res (2008) 0.92
Selective and specific internalization of clostridial C3 ADP-ribosyltransferases into macrophages and monocytes. Cell Microbiol (2009) 0.92
Results of volar locking plate osteosynthesis for distal radial fractures. J Trauma (2011) 0.92
A polyphenylene dendrimer-detergent complex as a highly fluorescent probe for bioassays. J Am Chem Soc (2003) 0.91
A molecular dynamics investigation of mono and dimeric states of the outer membrane enzyme OMPLA. J Mol Biol (2003) 0.91
Adipose tissue has anti-inflammatory properties: focus on IL-1 receptor antagonist (IL-1Ra). Ann N Y Acad Sci (2006) 0.91
Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons. J Neurochem (2005) 0.91
Phloem parenchyma transfer cells in Arabidopsis - an experimental system to identify transcriptional regulators of wall ingrowth formation. Front Plant Sci (2013) 0.91
Fast neurotransmitter release regulated by the endocytic scaffold intersectin. Proc Natl Acad Sci U S A (2013) 0.90
The host cell chaperone Hsp90 is necessary for cytotoxic action of the binary iota-like toxins. Infect Immun (2004) 0.90
Comparative virtual screening and novelty detection for NMDA-GlycineB antagonists. J Comput Aided Mol Des (2009) 0.90
Role of Rac and Cdc42 in lysophosphatidic acid-mediated cyclo-oxygenase-2 gene expression. Biochem J (2002) 0.89
Tailored ß-cyclodextrin blocks the translocation pores of binary exotoxins from C. botulinum and C. perfringens and protects cells from intoxication. PLoS One (2011) 0.89
Mechanism of C2-toxin inhibition by fluphenazine and related compounds: investigation of their binding kinetics to the C2II-channel using the current noise analysis. J Mol Biol (2003) 0.89
Chest injuries - what is new? Curr Opin Crit Care (2007) 0.89
Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin. J Mol Biol (2012) 0.88
Incorporation of nanoparticles into polymersomes: size and concentration effects. ACS Nano (2012) 0.88
Effects of enamel abrasion, salivary pellicle, and measurement angle on the optical assessment of dental erosion. J Biomed Opt (2012) 0.87
Interaction of the Rho-ADP-ribosylating C3 exoenzyme with RalA. J Biol Chem (2002) 0.87
Cationic nanohydrogel particles as potential siRNA carriers for cellular delivery. ACS Nano (2012) 0.87
The long-lived nature of clostridium perfringens iota toxin in mammalian cells induces delayed apoptosis. Infect Immun (2009) 0.86
Intra-abdominal pressure development after different temporary abdominal closure techniques in a porcine model. J Trauma (2009) 0.86
Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites. J Biol Chem (2003) 0.86
Influence of nongelling hydrocolloids on the gelation of agarose. Biomacromolecules (2013) 0.86
Human recombinant erythropoietin protects the striated muscle microcirculation of the dorsal skinfold from postischemic injury in mice. Am J Physiol Heart Circ Physiol (2007) 0.86
Discovery of 4-azaindoles as novel inhibitors of c-Met kinase. Bioorg Med Chem Lett (2009) 0.86
A core-shell albumin copolymer nanotransporter for high capacity loading and two-step release of doxorubicin with enhanced anti-leukemia activity. Adv Healthc Mater (2012) 0.86
Clostridium botulinum C2 toxin--new insights into the cellular up-take of the actin-ADP-ribosylating toxin. Int J Med Microbiol (2004) 0.86
How shape influences uptake: interactions of anisotropic polymer nanoparticles and human mesenchymal stem cells. Small (2012) 0.86
Direct measurements of hydrophobic slippage using double-focus fluorescence cross-correlation. Phys Rev Lett (2009) 0.86
Clostridial binary toxins: iota and C2 family portraits. Front Cell Infect Microbiol (2011) 0.86
Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells. Biochem Pharmacol (2006) 0.85
CD44 Promotes intoxication by the clostridial iota-family toxins. PLoS One (2012) 0.85
Visualizing picometric quantum ripples of ultrafast wave-packet interference. Science (2006) 0.85
Designed azolopyridinium salts block protective antigen pores in vitro and protect cells from anthrax toxin. PLoS One (2013) 0.84
A cell-permeable fusion toxin as a tool to study the consequences of actin-ADP-ribosylation caused by the salmonella enterica virulence factor SpvB in intact cells. J Biol Chem (2007) 0.84
Virtual screening for selective allosteric mGluR1 antagonists and structure-activity relationship investigations for coumarine derivatives. ChemMedChem (2007) 0.84
Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution. Nucleic Acids Res (2013) 0.84
Modifying the body distribution of HPMA-based copolymers by molecular weight and aggregate formation. Biomacromolecules (2011) 0.83
G13-dependent activation of MAPK by thyrotropin. J Biol Chem (2008) 0.83
FK506-binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells. Cell Microbiol (2012) 0.83
Optical pen-size reflectometer for monitoring of early dental erosion in native and polished enamels. J Biomed Opt (2013) 0.83
Structure-guided fragment-based in silico drug design of dengue protease inhibitors. J Comput Aided Mol Des (2011) 0.83
Genetically engineered clostridial C2 toxin as a novel delivery system for living mammalian cells. Bioconjug Chem (2010) 0.83
Structure formation in bis(terpyridine) derivative adlayers: molecule-substrate versus molecule-molecule interactions. Langmuir (2007) 0.82
Interactions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins. Biophys J (2012) 0.82
Intramolecular Förster energy transfer in a dendritic system at the single molecule level. J Am Chem Soc (2002) 0.82
Supramolecular thiophene nanosheets. Angew Chem Int Ed Engl (2013) 0.82
Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA. J Am Soc Nephrol (2003) 0.82
C-clamp and pelvic packing for control of hemorrhage in patients with pelvic ring disruption. J Emerg Trauma Shock (2011) 0.82
Clinical comparison of two optional vena cava filters. J Vasc Interv Radiol (2007) 0.82
Peptide nanofibrils as enhancers of retroviral gene transfer. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2014) 0.82
Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes. J Cell Physiol (2015) 0.82
RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells. Am J Physiol Cell Physiol (2002) 0.82
Expanding the spectrum of PTH1R mutations in patients with primary failure of tooth eruption. Clin Oral Investig (2013) 0.82
Early detection of subclinical organ dysfunction by microdialysis of the rectus abdominis muscle in a porcine model of critical intra-abdominal hypertension. Shock (2012) 0.82
Fine-tuning DNA/albumin polyelectrolyte interactions to produce the efficient transfection agent cBSA-147. Biomaterials (2010) 0.82
Formation of a biologically active toxin complex of the binary Clostridium botulinum C2 toxin without cell membrane interaction. Biochemistry (2006) 0.82
Surface attachment of protein fibrils via covalent modification strategies. J Phys Chem B (2010) 0.81
C2-streptavidin mediates the delivery of biotin-conjugated tumor suppressor protein p53 into tumor cells. Bioconjug Chem (2013) 0.81