Published in Mech Dev on October 23, 2013
The cellular and molecular mechanisms of vertebrate lens development. Development (2014) 1.04
Comparative transcriptome analysis of epithelial and fiber cells in newborn mouse lenses with RNA sequencing. Mol Vis (2014) 0.99
Molecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genes. Exp Eye Res (2014) 0.84
Development of novel filtering criteria to analyze RNA-sequencing data obtained from the murine ocular lens during embryogenesis. Genom Data (2014) 0.83
Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression. Development (2015) 0.81
Beta-1 integrin is important for the structural maintenance and homeostasis of differentiating fiber cells. Int J Biochem Cell Biol (2014) 0.81
Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol (2015) 0.80
Lens extrusion from Laminin alpha 1 mutant zebrafish. ScientificWorldJournal (2014) 0.79
Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn (2015) 0.79
Systems biology of lens development: A paradigm for disease gene discovery in the eye. Exp Eye Res (2016) 0.77
Novel phenotypes and loci identified through clinical genomics approaches to pediatric cataract. Hum Genet (2016) 0.77
The Zeb proteins δEF1 and Sip1 may have distinct functions in lens cells following cataract surgery. Invest Ophthalmol Vis Sci (2014) 0.76
RNA-binding proteins in eye development and disease: implication of conserved RNA granule components. Wiley Interdiscip Rev RNA (2016) 0.75
β1-integrin controls cell fate specification in early lens development. Differentiation (2016) 0.75
The molecular mechanisms underlying lens fiber elongation. Exp Eye Res (2016) 0.75
Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals. Development (2016) 0.75
An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and disease. Genom Data (2015) 0.75
Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations. Sci Rep (2017) 0.75
β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci (2017) 0.75
Signaling and Gene Regulatory Networks in Mammalian Lens Development. Trends Genet (2017) 0.75
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89
The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell (1982) 19.91
Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq. Genome Res (2011) 6.90
NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2. Oncogene (2006) 3.91
Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev (2000) 3.85
Lens differentiation in vertebrates. A review of cellular and molecular features. Differentiation (1981) 3.65
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic Acids Res (2005) 3.41
SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes. J Biol Chem (1999) 3.35
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J (2004) 3.31
Differential expression in SAGE: accounting for normal between-library variation. Bioinformatics (2003) 3.06
The role of Pax-6 in eye and nasal development. Development (1995) 3.00
The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci (2009) 2.95
New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites. EMBO J (1999) 2.47
Growth factor regulation of lens development. Dev Biol (2005) 2.46
The delta-crystallin enhancer-binding protein delta EF1 is a repressor of E2-box-mediated gene activation. Mol Cell Biol (1994) 2.27
Purification and architecture of the ubiquitous Wave complex. Proc Natl Acad Sci U S A (2004) 2.25
Age-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: does deamidation contribute to crystallin insolubility? J Proteome Res (2006) 2.17
Regulation of vimentin by SIP1 in human epithelial breast tumor cells. Oncogene (2006) 2.09
Clinical features and management issues in Mowat-Wilson syndrome. Am J Med Genet A (2006) 1.97
Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome. Am J Hum Genet (2003) 1.88
Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. Neuron (2013) 1.87
Lens development and crystallin gene expression: many roles for Pax-6. Bioessays (1996) 1.87
DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation. Dev Cell (2006) 1.75
Mowat-Wilson syndrome. J Med Genet (2003) 1.75
Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells. Mol Cell Biol (2006) 1.63
Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol (2008) 1.58
Systematic analysis of E-, N- and P-cadherin expression in mouse eye development. Exp Eye Res (2002) 1.57
Genetic and epigenetic mechanisms of gene regulation during lens development. Prog Retin Eye Res (2007) 1.56
Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age. Invest Ophthalmol Vis Sci (2002) 1.55
Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci (2009) 1.54
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. Dev Biol (2008) 1.53
Clinical and mutational spectrum of Mowat-Wilson syndrome. Eur J Med Genet (2005) 1.46
Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice. Invest Ophthalmol Vis Sci (2004) 1.40
Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching. Development (2006) 1.38
Mowat-Wilson syndrome. Orphanet J Rare Dis (2007) 1.37
Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes Dev (2007) 1.36
Generation of the floxed allele of the SIP1 (Smad-interacting protein 1) gene for Cre-mediated conditional knockout in the mouse. Genesis (2002) 1.34
Dual roles for Pax-6: a transcriptional repressor of lens fiber cell-specific beta-crystallin genes. Mol Cell Biol (1998) 1.30
Eye development. Curr Top Dev Biol (2010) 1.27
Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays. J Biol Chem (2002) 1.26
Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Dev Biol (2008) 1.21
Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation. Development (2005) 1.20
Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens. Int J Dev Biol (2004) 1.20
Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract. J Biol Chem (2009) 1.19
Optimal lens epithelial cell proliferation is dependent on the connexin isoform providing gap junctional coupling. Invest Ophthalmol Vis Sci (2007) 1.19
Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Neuron (2012) 1.18
The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood (2011) 1.12
Pax6 is essential for lens fiber cell differentiation. Development (2009) 1.12
Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proc Natl Acad Sci U S A (2007) 1.12
iSyTE: integrated Systems Tool for Eye gene discovery. Invest Ophthalmol Vis Sci (2012) 1.11
Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene. Proc Natl Acad Sci U S A (1995) 1.11
Three-dimensional reconstruction of cells in the living lens: the relationship between cell length and volume. Exp Eye Res (2005) 1.07
Role of short-range protein interactions in lens opacifications. Mol Vis (2006) 1.06
An immunohistochemical method for the detection of proteins in the vertebrate lens. J Immunol Methods (2001) 1.06
Cellular and molecular features of lens differentiation: a review of recent advances. Differentiation (1996) 1.04
Truncated forms of Pax-6 disrupt lens morphology in transgenic mice. Invest Ophthalmol Vis Sci (2000) 1.03
Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells. Dev Biol (2011) 1.02
Organization of the mouse Zfhx1b gene encoding the two-handed zinc finger repressor Smad-interacting protein-1. Genomics (2003) 0.98
Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. PLoS One (2013) 0.96
SIP1 (Smad interacting protein 1) and deltaEF1 (delta-crystallin enhancer binding factor) are structurally similar transcriptional repressors. J Bone Joint Surg Am (2001) 0.94
Corneal goblet cells and their niche: implications for corneal stem cell deficiency. Stem Cells (2012) 0.94
Identification of the role of Smad interacting protein 1 (SIP1) in glioma. J Neurooncol (2009) 0.92
Pleiotropic and diverse expression of ZFHX1B gene transcripts during mouse and human development supports the various clinical manifestations of the "Mowat-Wilson" syndrome. Neurobiol Dis (2004) 0.92
Regulation of vimentin gene expression in the ocular lens. Dev Biol (1990) 0.92
A method for determining cell number in the undisturbed epithelium of the mouse lens. Mol Vis (2010) 0.92
Expression of the SMADIP1 gene during early human development. Mech Dev (2002) 0.90
Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis. Mol Biol Cell (2010) 0.89
Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol (2011) 0.88
An atypical form of alphaB-crystallin is present in high concentration in some human cataractous lenses. Identification and characterization of aberrant N- and C-terminal processing. J Biol Chem (1999) 0.88
Nerves and neovessels inhibit each other in the cornea. Invest Ophthalmol Vis Sci (2013) 0.88
Susceptibility of ovine lens crystallins to proteolytic cleavage during formation of hereditary cataract. Invest Ophthalmol Vis Sci (2008) 0.87
Hirschsprung disease, mental retardation, characteristic facial features, and mutation in the gene ZFHX1B (SIP1): confirmation of the Mowat-Wilson syndrome. Am J Med Genet A (2003) 0.87
Altered expression and insulin-induced trafficking of Na+-K+-ATPase in rat skeletal muscle: effects of high-fat diet and exercise. Am J Physiol Endocrinol Metab (2009) 0.82
The transcription factor Smad-interacting protein 1 controls pain sensitivity via modulation of DRG neuron excitability. Pain (2011) 0.82
Analysis of PCP defects in mammalian eye lens. Methods Mol Biol (2012) 0.81
Focus on molecules: Smad Interacting Protein 1 (Sip1, ZEB2, ZFHX1B). Exp Eye Res (2010) 0.79
Isolation of messenger RNA. Methods Mol Biol (1998) 0.79
Ophthalmologic abnormalities in Mowat-Wilson syndrome and a mutation in ZEB2. Ophthalmic Genet (2012) 0.78
The molecular mechanisms underlying lens fiber elongation. Exp Eye Res (2016) 0.75
β1-integrin controls cell fate specification in early lens development. Differentiation (2016) 0.75