Published in J Biol Response Mod on December 01, 1985
Neoadjuvant Hiltonol® (PolyICLC) for Prostate Cancer | NCT03262103
TLR-based immune adjuvants. Vaccine (2010) 2.10
Trial Watch: Experimental Toll-like receptor agonists for cancer therapy. Oncoimmunology (2012) 1.88
Toll-like receptor agonists in cancer therapy. Immunotherapy (2009) 1.58
A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05). J Neurooncol (2008) 1.37
A North American brain tumor consortium phase II study of poly-ICLC for adult patients with recurrent anaplastic gliomas. J Neurooncol (2008) 1.18
TLR agonists: our best frenemy in cancer immunotherapy. J Leukoc Biol (2013) 1.18
Toll-like receptor agonists: are they good adjuvants? Cancer J (2010) 1.16
Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients. J Natl Cancer Inst (2012) 0.98
Targeting the innate immune system as immunotherapy for acute myeloid leukemia. Front Oncol (2015) 0.89
Broad-spectrum drugs against viral agents. Int J Mol Sci (2008) 0.81
TLR3 agonists and proinflammatory antitumor activities. Expert Opin Ther Targets (2013) 0.77
Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol (1996) 9.68
A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. N Engl J Med (1996) 7.66
Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease. Meningococcal Research Group. Lancet (1999) 6.02
Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guérin infection. N Engl J Med (1996) 5.36
Dysfunction of endothelial protein C activation in severe meningococcal sepsis. N Engl J Med (2001) 4.10
Morbidity and severity of illness during interhospital transfer: impact of a specialised paediatric retrieval team. BMJ (1995) 4.05
The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils. J Clin Invest (1972) 3.96
Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery. Arch Dis Child (2001) 3.94
Emergency management of meningococcal disease. Arch Dis Child (1999) 3.93
Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis (2003) 3.73
Immunologic studies of the major nonimmunoglobulin protein of amyloid. I. Identification and partial characterization of a related serum component. J Exp Med (1973) 3.22
Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series. BMJ (1997) 2.93
Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guérin infection and a sibling with clinical tuberculosis. J Clin Invest (1997) 2.76
Unsuspected HIV infection presenting in first year of life. BMJ (1995) 2.62
Immunoregulatory properties of ISG15, an interferon-induced cytokine. Proc Natl Acad Sci U S A (1996) 2.45
Isolation and characterization of cDNA clones for human skeletal muscle alpha actin. Nucleic Acids Res (1983) 2.45
Multiple tracer dilution estimates of D- and 2-deoxy-D-glucose uptake by the heart. Am J Physiol (1986) 2.39
Diseases that mimic herpes simplex encephalitis. Diagnosis, presentation, and outcome. NIAD Collaborative Antiviral Study Group. JAMA (1989) 2.38
A myocardial cytotoxic process is involved in the cardiac dysfunction of meningococcal septic shock. Crit Care Med (2000) 2.35
Management of Kawasaki disease. Arch Dis Child (2013) 2.30
Severe P. falciparum malaria in Kenyan children: evidence for hypovolaemia. QJM (2003) 2.18
Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ (2004) 2.17
Acute inflammation of the temporomandibular joint presenting as classical trigeminal neuralgia--case report and hypothesis. Headache (1988) 2.16
Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research. Arch Dis Child (2002) 2.11
Guidelines for the use of fresh frozen plasma. British Committee for Standards in Haematology, Working Party of the Blood Transfusion Task Force. Transfus Med (1992) 2.07
Human polyomavirus infections with JC virus and BK virus in renal transplant patients. Ann Intern Med (1980) 2.07
Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons. Cancer Res (1998) 2.04
Association of intraoperative blood pressure instability with adverse outcomes after liver transplantation. Minerva Anestesiol (2013) 2.03
In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine. J Immunol (1996) 1.98
Sensitivity analysis in optimization of time-distributed parameters for a coronary circulation model. Med Prog Technol (1980) 1.98
The course of severe chronic fatigue syndrome in childhood. J R Soc Med (2000) 1.93
Abraxane, a novel Cremophor-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer. Ann Oncol (2006) 1.92
Psychiatric adjustment in adolescents with a history of chronic fatigue syndrome. J Am Acad Child Adolesc Psychiatry (1999) 1.91
Potentially lethal bacterial infection associated with varicella zoster virus. BMJ (1996) 1.88
Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses. Cancer Res (1987) 1.87
Erythema migrans-like rash illness at a camp in North Carolina: a new tick-borne disease? Arch Intern Med (1998) 1.80
Does computed tomography have a role in the evaluation of complicated acute bacterial meningitis in childhood? Dev Med Child Neurol (1992) 1.79
Physicochemical and morphological relationships of some arthropod-borne viruses to bluetongue virus--a new taxonomic group. Physiocochemical and serological studies. J Gen Virol (1971) 1.78
Interferon-induced indoleamine 2,3-dioxygenase activity inhibits Chlamydia psittaci replication in human macrophages. J Interferon Res (1989) 1.74
Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines. Clin Cancer Res (2001) 1.73
Induction of tryptophan degradation in vitro and in vivo: a gamma-interferon-stimulated activity. J Interferon Res (1986) 1.70
Avoidable deficiencies in the delivery of health care to children with meningococcal disease. J Accid Emerg Med (1998) 1.65
Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures. J Immunol (1987) 1.65
Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease. J Infect Dis (1996) 1.64
Disruption of sulphated glycosaminoglycans in intestinal inflammation. Lancet (1993) 1.64
Evidence of hypoxic areas within the arterial wall in vivo. Arterioscler Thromb Vasc Biol (1999) 1.58
Toxic shock syndrome. Arch Dis Child (1985) 1.58
Physicochemical and morphological relationships of some arthropod-borne viruses to bluetongue virus--a new taxonomic group. Electron microscopic studies. J Gen Virol (1971) 1.56
Concepts of fever: recent advances and lingering dogma. Clin Infect Dis (1997) 1.50
Sudden death from bronchial asthma. Am Rev Respir Dis (1966) 1.50
Metastatic malignant melanoma treated with combined bolus and continuous infusion interleukin-2 and lymphokine-activated killer cells. J Clin Oncol (1990) 1.49
CSF and MRI findings in patients with acute herpes zoster. Neurology (1998) 1.49
A human 15-kDa IFN-induced protein induces the secretion of IFN-gamma. J Immunol (1991) 1.47
Metastatic renal cancer treated with interleukin-2 and lymphokine-activated killer cells. A phase II clinical trial. Ann Intern Med (1988) 1.46
Pedunculated malignant melanoma. Dermatol Surg (2000) 1.46
Haemorrhagic shock and encephalopathy: a new syndrome with a high mortality in young children. Lancet (1983) 1.46
Paclitaxel for platinum-refractory ovarian cancer: results from the first 1,000 patients registered to National Cancer Institute Treatment Referral Center 9103. J Clin Oncol (1993) 1.44
Varicella-zoster virus-specific immunity after herpes zoster. J Infect Dis (1991) 1.44
Meningitis and meningococcal septicaemia. J R Coll Physicians Lond (1998) 1.44
Matrix metalloproteinase inhibitors. Invest New Drugs (1997) 1.43
A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer. Clin Cancer Res (1999) 1.42
Randomized comparison of three adriamycin regimens for metastatic soft tissue sarcomas. J Clin Oncol (1987) 1.42
Rapid detection and identification of JC virus and BK virus in human urine by using immunofluorescence microscopy. J Clin Microbiol (1980) 1.42
Composition of coronary plaques obtained by directional atherectomy in stable angina: its relation to serum lipids and statin treatment. J Intern Med (2006) 1.41
Interferon-induced indoleamine 2,3-dioxygenase activity in human mononuclear phagocytes. J Leukoc Biol (1989) 1.41
Haemolytic uraemic syndrome. Arch Dis Child (1984) 1.41
Streptococcus associated toxic shock. Arch Dis Child (1992) 1.41
Complete recovery from hemorrhagic shock and encephalopathy. J Pediatr (1992) 1.40
Endotoxin antibody for sepsis in infants. Lancet (1992) 1.40
Randomised controlled trial of the efficacy of a metered dose inhaler with bottle spacer for bronchodilator treatment in acute lower airway obstruction. Arch Dis Child (2006) 1.39
Evaluation of human antimycobacterial immunity using recombinant reporter mycobacteria. J Infect Dis (2000) 1.39
Pathologic analysis of advanced adult soft tissue sarcomas, bone sarcomas, and mesotheliomas. The Eastern Cooperative Oncology Group (ECOG) experience. Cancer (1989) 1.38
The Pathogenesis of Cataplexy on Anger. J Neurol Psychopathol (1935) 1.38
The diagnostic accuracy of ex vivo MRI for human atherosclerotic plaque characterization. Arterioscler Thromb Vasc Biol (1999) 1.37
The partial amino acid sequence of the major low molecular weight component of two human amyloid fibrils. FEBS Lett (1972) 1.35
Inhibitor of prostacyclin production in sporadic haemolytic uraemic syndrome. Arch Dis Child (1983) 1.35
The interferon refractory state: in vivo and in vitro studies of its mechanism. J Immunol (1971) 1.34
Evidence for a superantigen mediated process in Kawasaki disease. Arch Dis Child (1995) 1.34
Genetic influence on cytokine production in meningococcal disease. Lancet (1997) 1.33
Interferons and indoleamine 2,3-dioxygenase: role in antimicrobial and antitumor effects. Experientia (1989) 1.33
Risk factors for clinical salmonellosis in Virginia, USA cattle herds. Prev Vet Med (2001) 1.32
Left-right asymmetry determination in vertebrates. Annu Rev Cell Dev Biol (2001) 1.31
Association between Gc genotype and susceptibility to TB is dependent on vitamin D status. Eur Respir J (2009) 1.30
4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease. Meningococcal Research Group. Lancet (1999) 1.28
Comparative antiproliferative activity in vitro of natural interferons alpha and beta for diploid and transformed human cells. Cancer Res (1982) 1.25
Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer. J Clin Oncol (1998) 1.25
Central pontine myelinolysis. Considerations on etiology, diagnosis, and treatment. Neurology (1979) 1.23
Ectopic lipid storage and insulin resistance: a harmful relationship. J Intern Med (2013) 1.22
Cerberus regulates left-right asymmetry of the embryonic head and heart. Curr Biol (1999) 1.22
Evaluation and management of headache in the emergency department. Med Clin North Am (2001) 1.21
Beta interferon inhibits Toxoplasma gondii growth in human monocyte-derived macrophages. Infect Immun (1989) 1.20
Pathophysiology and management of meningococcal septicaemia. J R Coll Physicians Lond (2001) 1.20
The orthopaedic management of peripheral ischaemia in meningococcal septicaemia in children. J Bone Joint Surg Br (2000) 1.20
Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori. Int J Antimicrob Agents (2001) 1.20
A direct comparison of biological response modulation and clinical side effects by interferon-beta ser, interferon-gamma, or the combination of interferons beta ser and gamma in humans. J Clin Invest (1990) 1.20
Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines. J Clin Oncol (1989) 1.19
Fetal pulmonary hypoplasia, anuria, and oligohydramnios: clinicopathologic observations and review of the literature. Am J Obstet Gynecol (1974) 1.17
Early markers of the renal complications of insulin dependent diabetes mellitus. Arch Dis Child (1989) 1.17
Effect of tissue temperatures and blood flow on motor nerve conduction velocity. JAMA (1966) 1.16
Human albumin administration in critically ill patients. Review did not provide recommendations for alternative treatment. BMJ (1998) 1.16