Rongtuan Lin

Author PubWeight™ 90.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Triggering the interferon antiviral response through an IKK-related pathway. Science 2003 11.62
2 Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes. J Virol 2002 4.31
3 The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat Immunol 2007 2.91
4 Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA. J Biol Chem 2003 2.57
5 MasterCARD: a priceless link to innate immunity. Trends Mol Med 2006 2.29
6 Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus. J Biol Chem 2007 2.07
7 Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity. J Virol 2004 2.06
8 Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation. J Virol 2002 2.04
9 Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression. J Virol 2005 2.02
10 Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex. Cell Host Microbe 2012 1.93
11 Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression. J Virol 2006 1.75
12 Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon. J Virol 2005 1.72
13 The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation. PLoS Pathog 2009 1.57
14 Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon. J Immunol 2006 1.56
15 Convergence of the NF-kappaB and interferon signaling pathways in the regulation of antiviral defense and apoptosis. Ann N Y Acad Sci 2003 1.55
16 Targeting dendritic cell signaling to regulate the response to immunization. Blood 2008 1.50
17 Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter. Mol Cell Biol 2009 1.49
18 Overlapping and distinct mechanisms regulating IRF-3 and IRF-7 function. J Interferon Cytokine Res 2002 1.26
19 Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages. Cancer Res 2006 1.25
20 Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3. J Virol 2011 1.24
21 Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines. Microbes Infect 2006 1.22
22 Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Blood 2005 1.20
23 A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response. Cell Res 2011 1.18
24 Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5. J Virol 2012 1.14
25 Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7. Eur J Immunol 2009 1.12
26 Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS. J Biol Chem 2009 1.11
27 Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription. J Mol Biol 2002 1.09
28 Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression. Virol J 2006 1.08
29 Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells. J Immunol 2007 1.07
30 Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity. PLoS Pathog 2013 1.07
31 Host restriction factor SAMHD1 limits human T cell leukemia virus type 1 infection of monocytes via STING-mediated apoptosis. Cell Host Microbe 2013 1.03
32 Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response. J Virol 2014 1.03
33 Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7. Mol Cell Biol 2009 1.03
34 Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins. J Virol 2005 1.03
35 Kaposi sarcoma-associated herpesvirus degrades cellular Toll-interleukin-1 receptor domain-containing adaptor-inducing beta-interferon (TRIF). J Biol Chem 2011 1.01
36 A requirement for NF-kappaB induction in the production of replication-competent HHV-8 virions. Oncogene 2004 1.01
37 Bax-dependent mitochondrial membrane permeabilization enhances IRF3-mediated innate immune response during VSV infection. Virology 2007 0.97
38 In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors. Cancer Res 2002 0.96
39 UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS. Cell Rep 2013 0.95
40 Histone deacetylase inhibitors potentiate vesicular stomatitis virus oncolysis in prostate cancer cells by modulating NF-κB-dependent autophagy. J Virol 2013 0.95
41 ELF4 is critical for induction of type I interferon and the host antiviral response. Nat Immunol 2013 0.95
42 Herpes simplex virus 1-encoded tegument protein VP16 abrogates the production of beta interferon (IFN) by inhibiting NF-κB activation and blocking IFN regulatory factor 3 to recruit its coactivator CBP. J Virol 2013 0.95
43 Herpes simplex virus 1 serine/threonine kinase US3 hyperphosphorylates IRF3 and inhibits beta interferon production. J Virol 2013 0.95
44 Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease. Biochem Pharmacol 2006 0.94
45 Suppression of IRF4 by IRF1, 3, and 7 in Noxa expression is a necessary event for IFN-γ-mediated tumor elimination. Mol Cancer Res 2011 0.94
46 STING-ing the antiviral pathway. J Mol Cell Biol 2009 0.93
47 Bioactivity determination of native and variant forms of therapeutic interferons. J Biomed Biotechnol 2011 0.92
48 Repression of IRF-4 target genes in human T cell leukemia virus-1 infection. Oncogene 2002 0.89
49 SAMHD1 host restriction factor: a link with innate immune sensing of retrovirus infection. J Mol Biol 2013 0.88
50 Functional analysis of a dominant negative mutation of interferon regulatory factor 5. PLoS One 2009 0.88
51 The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway. PLoS One 2013 0.87
52 Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon. J Biol Chem 2005 0.87
53 Super-activated interferon-regulatory factors can enhance plasmid immunization. Vaccine 2003 0.86
54 Disruption of the B-cell specific transcriptional program in HHV-8 associated primary effusion lymphoma cell lines. Oncogene 2003 0.86
55 The IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}. Mol Endocrinol 2009 0.83
56 IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis. J Virol 2011 0.81
57 Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7. J Virol 2010 0.80
58 Triptolide-mediated inhibition of interferon signaling enhances vesicular stomatitis virus-based oncolysis. Mol Ther 2013 0.80
59 Leukotriene A4 hydrolase expression in PEL cells is regulated at the transcriptional level and leads to increased leukotriene B4 production. J Immunol 2006 0.80
60 Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response. FEBS J 2005 0.80
61 NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection. Eur J Immunol 2014 0.80
62 Intact type I Interferon production and IRF7 function in sooty mangabeys. PLoS Pathog 2013 0.80
63 Inhibition of the interferon antiviral response by hepatitis C virus. Expert Rev Clin Immunol 2006 0.78
64 Recruitment of histone deacetylase 3 to the interferon-A gene promoters attenuates interferon expression. PLoS One 2012 0.77
65 IRF-3 releases its inhibitions. Structure 2005 0.76
66 Learning from estrogen receptor antagonism: structure-based identification of novel antiandrogens effective against multiple clinically relevant androgen receptor mutants. Chem Biol Drug Des 2012 0.75
67 Synthesis and in vitro characterization of ionone-based compounds as dual inhibitors of the androgen receptor and NF-κB. Invest New Drugs 2013 0.75