Published in BMC Med on November 05, 2013
Optimization of Preventive Effects of Physical Training (SAusE) | NCT01263522
Low brown adipose tissue activity in endurance-trained compared with lean sedentary men. Int J Obes (Lond) (2015) 1.66
Irisin - a myth rather than an exercise-inducible myokine. Sci Rep (2015) 1.39
Association of irisin with fat mass, resting energy expenditure, and daily activity in conditions of extreme body mass index. Int J Endocrinol (2014) 1.01
Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice. Int J Obes (Lond) (2014) 0.93
Regulators of human white adipose browning: evidence for sympathetic control and sexual dimorphic responses to sprint interval training. PLoS One (2014) 0.93
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Irisin levels are lower in young amenorrheic athletes compared with eumenorrheic athletes and non-athletes and are associated with bone density and strength estimates. PLoS One (2014) 0.89
Circulating irisin levels are positively associated with metabolic risk factors in sedentary subjects. PLoS One (2015) 0.88
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Plasma irisin in runners and nonrunners: no favorable metabolic associations in humans. Physiol Rep (2015) 0.81
Irisin in blood increases transiently after single sessions of intense endurance exercise and heavy strength training. PLoS One (2015) 0.81
Endurance training-induced increase in circulating irisin levels is associated with reduction of abdominal visceral fat in middle-aged and older adults. PLoS One (2015) 0.81
Central and peripheral irisin differentially regulate blood pressure. Cardiovasc Drugs Ther (2015) 0.79
Effects of lifestyle modification and metformin on irisin and FGF21 among HIV-infected subjects with the metabolic syndrome. Clin Endocrinol (Oxf) (2014) 0.77
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Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans. Appetite (2015) 0.76
Voluntary stand-up physical activity enhances endurance exercise capacity in rats. Korean J Physiol Pharmacol (2016) 0.76
Effects of Body Weight Reduction on Serum Irisin and Metabolic Parameters in Obese Subjects. Diabetes Metab J (2016) 0.75
Plasma Irisin Modestly Increases during Moderate and High-Intensity Afternoon Exercise in Obese Females. PLoS One (2017) 0.75
Circulating Irisin Concentrations Are Associated with a Favourable Lipid Profile in the General Population. PLoS One (2016) 0.75
Regular physical activity and cardiovascular biomarkers in prevention of atherosclerosis in men: a 25-year prospective cohort study. BMC Cardiovasc Disord (2016) 0.75
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American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. Med Sci Sports Exerc (2009) 5.35
Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Natl Acad Sci U S A (2009) 5.19
Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol (2012) 4.87
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Serum irisin levels in new-onset type 2 diabetes. Diabetes Res Clin Pract (2013) 2.03
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Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity--correlation with body mass index. Peptides (2012) 1.95
Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training. Diabetologia (2010) 1.57
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Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure. Circ Heart Fail (2012) 1.46
An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle. Am J Physiol Regul Integr Comp Physiol (2011) 1.46
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Irisin: a new potential hormonal target for the treatment of obesity and type 2 diabetes. J Diabetes (2012) 1.31
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Irisin, turning up the heat. Cell Metab (2012) 1.15
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Muscle metabolism and performance improvement after two training programmes of sprint running differing in rest interval duration. J Sports Sci (2011) 0.93
Association between postexercise hypotension and long-term training-induced blood pressure reduction: a pilot study. Clin J Sport Med (2013) 0.93
Time-course of the antihypertensive and autonomic effects of regular endurance exercise in human subjects. J Hypertens (1990) 0.91
Effect of physical training on the insulin resistance of aging. Am J Physiol (1989) 0.91
Effect of sex differences on human MEF2 regulation during endurance exercise. Am J Physiol Endocrinol Metab (2007) 0.91
Basic research: Irisin--behind the benefits of exercise. Nat Rev Endocrinol (2012) 0.91
Rapid onset and offset of circulatory adaptations to exercise training in men. J Hum Hypertens (2006) 0.88
Time course of changes in endurance capacity: a 1-yr training study. Med Sci Sports Exerc (2009) 0.85
Metabolic disease: Exercise hormone fights metabolic disease. Nat Rev Drug Discov (2012) 0.79
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Hippocampal plasticity in response to exercise in schizophrenia. Arch Gen Psychiatry (2010) 3.42
EASL and mRECIST responses are independent prognostic factors for survival in hepatocellular cancer patients treated with transarterial embolization. J Hepatol (2011) 2.37
Lactate threshold concepts: how valid are they? Sports Med (2009) 2.32
Clinical outcomes of radiofrequency ablation, percutaneous alcohol and acetic acid injection for hepatocelullar carcinoma: a meta-analysis. J Hepatol (2010) 2.31
Circulating tumor cells as prognostic markers in neuroendocrine tumors. J Clin Oncol (2012) 2.28
Inflammation-based scores do not predict post-transplant recurrence of hepatocellular carcinoma in patients within Milan criteria. Liver Transpl (2014) 2.11
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Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med (2012) 1.93
A consensus view of protein dynamics. Proc Natl Acad Sci U S A (2007) 1.73
Treatment outcomes for hepatocellular carcinoma using chemoembolization in combination with other therapies. Cancer Treat Rev (2006) 1.63
Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall. Circulation (2009) 1.63
Somatic mutation of CDKN1B in small intestine neuroendocrine tumors. Nat Genet (2013) 1.56
Functional NMDA receptors in rat erythrocytes. Am J Physiol Cell Physiol (2010) 1.54
Vaccination in elite athletes. Sports Med (2014) 1.50
Sustained activity of calcium release-activated calcium channels requires translocation of mitochondria to the plasma membrane. J Biol Chem (2006) 1.48
Arrhythmia causes lipid accumulation and reduced glucose uptake. Basic Res Cardiol (2015) 1.45
Running 8000 m fast or slow: Are there differences in energy cost and fat metabolism? Med Sci Sports Exerc (2005) 1.40
Straight sprinting is the most frequent action in goal situations in professional football. J Sports Sci (2012) 1.39
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A systematic review of microvascular invasion in hepatocellular carcinoma: diagnostic and prognostic variability. Ann Surg Oncol (2012) 1.33
Reduced cardiac L-type Ca2+ current in Ca(V)beta2-/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation. Circ Res (2006) 1.24
Identification of PatL1, a human homolog to yeast P body component Pat1. Biochim Biophys Acta (2007) 1.21
Bimolecular interaction of insulin-like growth factor (IGF) binding protein-2 with alphavbeta3 negatively modulates IGF-I-mediated migration and tumor growth. Cancer Res (2004) 1.21
Transarterial therapies for hepatocellular carcinoma (HCC): a long way towards standardization. J Hepatol (2012) 1.15
Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands. J Immunol (2010) 1.13
Different properties of VEGF-antagonists: Bevacizumab but not Ranibizumab accumulates in RPE cells. Graefes Arch Clin Exp Ophthalmol (2009) 1.09
Physiological characteristics of badminton match play. Eur J Appl Physiol (2007) 1.05
Exercise at given percentages of VO2max: heterogeneous metabolic responses between individuals. J Sci Med Sport (2009) 1.04
A system for optical high resolution screening of electrical excitable cells. Cell Calcium (2009) 1.03
Calcium in red blood cells-a perilous balance. Int J Mol Sci (2013) 1.02
γ-H2AX foci formation as a pharmacodynamic marker of DNA damage produced by DNA cross-linking agents: results from 2 phase I clinical trials of SJG-136 (SG2000). Clin Cancer Res (2012) 1.02
DNA double-strand break rejoining in complex normal tissues. Int J Radiat Oncol Biol Phys (2008) 1.01
Circulating tumor cells and EpCAM expression in neuroendocrine tumors. Clin Cancer Res (2011) 1.01
Red cell investigations: art and artefacts. Blood Rev (2013) 1.00
Reproducibility and clinical significance of exercise-induced increases in cardiac troponins and N-terminal pro brain natriuretic peptide in endurance athletes. Eur J Cardiovasc Prev Rehabil (2006) 0.99
Cardiac Rac1 overexpression in mice creates a substrate for atrial arrhythmias characterized by structural remodelling. Cardiovasc Res (2010) 0.97
Isolation and genetic manipulation of adult cardiac myocytes for confocal imaging. J Vis Exp (2009) 0.94
Overexpression of junctin causes adaptive changes in cardiac myocyte Ca(2+) signaling. Cell Calcium (2005) 0.94
Cytotoxic treatment including embolization/chemoembolization for neuroendocrine tumours. Best Pract Res Clin Endocrinol Metab (2007) 0.94
Cooling and performance recovery of trained athletes: a meta-analytical review. Int J Sports Physiol Perform (2013) 0.93
Unmasking of alpha-fetoprotein-specific CD4(+) T cell responses in hepatocellular carcinoma patients undergoing embolization. J Immunol (2007) 0.93
Association between postexercise hypotension and long-term training-induced blood pressure reduction: a pilot study. Clin J Sport Med (2013) 0.93
Exploring protein dynamics space: the dynasome as the missing link between protein structure and function. PLoS One (2012) 0.93
Regulation of phosphatidylserine exposure in red blood cells. Cell Physiol Biochem (2011) 0.92
Sleep and athletic performance: the effects of sleep loss on exercise performance, and physiological and cognitive responses to exercise. Sports Med (2015) 0.91
Hepatocellular carcinoma. N Engl J Med (2012) 0.91
Developments in single photon emission computed tomography and PET-based HER2 molecular imaging for breast cancer. Expert Rev Anticancer Ther (2013) 0.89
Stimulation of human red blood cells leads to Ca2+-mediated intercellular adhesion. Cell Calcium (2011) 0.88
N-methyl-D-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the intracellular calcium regulation. Am J Physiol Cell Physiol (2013) 0.88
Multivalent binding of formin-binding protein 21 (FBP21)-tandem-WW domains fosters protein recognition in the pre-spliceosome. J Biol Chem (2011) 0.88
Sarcoidosis and testicular cancer: A case series and literature review. Urol Oncol (2008) 0.87
Genetically encoded Ca2+ indicators in cardiac myocytes. Circ Res (2014) 0.87
Functional and morphological preservation of adult ventricular myocytes in culture by sub-micromolar cytochalasin D supplement. J Mol Cell Cardiol (2011) 0.87
Pre-cooling and sports performance: a meta-analytical review. Sports Med (2012) 0.87
Transarterial embolization as neo-adjuvant therapy pretransplantation in patients with hepatocellular carcinoma. Liver Int (2013) 0.86
Assessment of neuromuscular function after different strength training protocols using tensiomyography. J Strength Cond Res (2015) 0.86
Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus. J Mol Biol (2008) 0.85
Time course of changes in endurance capacity: a 1-yr training study. Med Sci Sports Exerc (2009) 0.85
Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism. PLoS One (2012) 0.85
Morphologically homogeneous red blood cells present a heterogeneous response to hormonal stimulation. PLoS One (2013) 0.84
Imaging in targeted delivery of therapy to cancer. Target Oncol (2009) 0.84
Malignant somatostatinoma presenting with diabetic ketoacidosis and inhibitory syndrome: pathophysiologic considerations. Endocr Pract (2011) 0.84
Transarterial injection of (131)I-lipiodol, compared with chemoembolization, in the treatment of unresectable hepatocellular cancer. J Nucl Med (2009) 0.84
Optical action potential screening on adult ventricular myocytes as an alternative QT-screen. Cell Physiol Biochem (2011) 0.84
Remodelling of Ca2+ handling organelles in adult rat ventricular myocytes during long term culture. J Mol Cell Cardiol (2010) 0.84
The combined effects of oncolytic reovirus plus Newcastle disease virus and reovirus plus parvovirus on U87 and U373 cells in vitro and in vivo. J Neurooncol (2011) 0.83
Protein flexibility from discrete molecular dynamics simulations using quasi-physical potentials. Proteins (2010) 0.83
Sudden cardiac death in football. J Sports Sci (2013) 0.83
Data mining of molecular dynamics trajectories of nucleic acids. J Biomol Struct Dyn (2006) 0.83
Pacing Differs Between Time- and Distance-Based Time Trials in Trained Cyclists. Int J Sports Physiol Perform (2016) 0.83
Effects of graded carbohydrate supplementation on the immune response in cycling. Med Sci Sports Exerc (2006) 0.82
Partition of protein solvation into group contributions from molecular dynamics simulations. Proteins (2005) 0.82
Injury prevention in male veteran football players - a randomised controlled trial using "FIFA 11+". J Sports Sci (2014) 0.82
A primary culture system for sustained expression of a calcium sensor in preserved adult rat ventricular myocytes. Cell Calcium (2007) 0.82
Exploring the possible role of Glu286 in CcO by electrostatic energy computations combined with molecular dynamics. J Phys Chem B (2013) 0.82
Bicarbonate infusion and pH clamp moderately reduce hyperventilation during ramp exercise in humans. J Appl Physiol (1985) (2006) 0.81
Return to play after acute infectious disease in football players. J Sports Sci (2014) 0.81
Linear response theory: an alternative to PB and GB methods for the analysis of molecular dynamics trajectories? Proteins (2004) 0.81
Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene. J Biol Chem (2011) 0.81
Parathyroid hormone-related peptide-secreting pancreatic neuroendocrine tumours: case series and literature review. Neuroendocrinology (2008) 0.81
High intensity interval training vs. high-volume running training during pre-season conditioning in high-level youth football: a cross-over trial. J Sports Sci (2013) 0.80
Role of everolimus in pancreatic neuroendocrine tumors. Expert Rev Anticancer Ther (2011) 0.80
Irisin does not mediate resistance training-induced alterations in resting metabolic rate. Med Sci Sports Exerc (2014) 0.80
Transarterial chemoembolisation is not superior to embolisation alone: the recent European Association for the Study of the Liver (EASL) - European Organisation for Research and Treatment of Cancer (EORTC) guidelines. Eur J Cancer (2012) 0.80
A phase I/II study of doxorubicin, ifosfamide, etoposide and interval methotrexate in patients with poor prognosis osteosarcoma. Pediatr Blood Cancer (2006) 0.80
Protein kinase Cα and P-type Ca channel CaV2.1 in red blood cell calcium signalling. Cell Physiol Biochem (2013) 0.80
Ca2+ channel currents and contraction in CaVbeta3-deficient ileum smooth muscle from mouse. Cell Calcium (2007) 0.80
Differential presentation of tumor antigen-derived epitopes by MHC-class I and antigen-positive tumor cells. Int J Cancer (2008) 0.80
Collagen-based engineered heart muscle. Methods Mol Biol (2014) 0.80