Published in Nat Biotechnol on November 01, 2013
Search for Bovine miRNA Transference to Humans | NCT03740087
The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells. J Nutr (2015) 1.17
Uptake and Function Studies of Maternal Milk-derived MicroRNAs. J Biol Chem (2015) 1.15
Reply to Lack of detectable oral bioavailability of plant microRNAs after feeding in mice. Nat Biotechnol (2013) 1.13
In silico identification of plant miRNAs in mammalian breast milk exosomes--a small step forward? PLoS One (2014) 1.09
Cross-kingdom inhibition of breast cancer growth by plant miR159. Cell Res (2016) 1.07
Detection of dietary plant-based small RNAs in animals. Cell Res (2015) 1.05
Mining of public sequencing databases supports a non-dietary origin for putative foreign miRNAs: underestimated effects of contamination in NGS. RNA (2014) 1.00
Non-coding RNA: a new frontier in regulatory biology. Natl Sci Rev (2014) 0.95
Milk: an exosomal microRNA transmitter promoting thymic regulatory T cell maturation preventing the development of atopy? J Transl Med (2014) 0.94
Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β. PLoS One (2015) 0.90
Environmental RNAi in herbivorous insects. RNA (2015) 0.90
Detection of an Abundant Plant-Based Small RNA in Healthy Consumers. PLoS One (2015) 0.89
Human vascular endothelial cells transport foreign exosomes from cow's milk by endocytosis. Am J Physiol Cell Physiol (2016) 0.89
MicroRNAs in Breastmilk and the Lactating Breast: Potential Immunoprotectors and Developmental Regulators for the Infant and the Mother. Int J Environ Res Public Health (2015) 0.88
Loss of miRNAs during processing and storage of cow's (Bos taurus) milk. J Agric Food Chem (2015) 0.87
New Concepts in Cancer Biomarkers: Circulating miRNAs in Liquid Biopsies. Int J Mol Sci (2016) 0.86
Biosafety research for non-target organism risk assessment of RNAi-based GE plants. Front Plant Sci (2015) 0.86
Computational Characterization of Exogenous MicroRNAs that Can Be Transferred into Human Circulation. PLoS One (2015) 0.86
Conversations between kingdoms: small RNAs. Curr Opin Biotechnol (2015) 0.85
The biology of circulating microRNAs in cardiovascular disease. Eur J Clin Invest (2015) 0.85
The circulating transcriptome as a source of non-invasive cancer biomarkers: concepts and controversies of non-coding and coding RNA in body fluids. J Cell Mol Med (2015) 0.85
miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy. PLoS One (2015) 0.84
No effect of an elevated miR-30b level in mouse milk on its level in pup tissues. RNA Biol (2015) 0.84
Human Milk MicroRNA and Total RNA Differ Depending on Milk Fractionation. J Cell Biochem (2015) 0.83
Dietary RNAs: New Stories Regarding Oral Delivery. Nutrients (2015) 0.82
Dietary MicroRNA Database (DMD): An Archive Database and Analytic Tool for Food-Borne microRNAs. PLoS One (2015) 0.81
Gene regulation by dietary microRNAs. Can J Physiol Pharmacol (2015) 0.81
The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus. Curr Diabetes Rev (2015) 0.80
Toward the promise of microRNAs - Enhancing reproducibility and rigor in microRNA research. RNA Biol (2016) 0.80
Horizontal Transfer of Small RNAs to and from Plants. Front Plant Sci (2015) 0.79
Human Milk Cells Contain Numerous miRNAs that May Change with Milk Removal and Regulate Multiple Physiological Processes. Int J Mol Sci (2016) 0.79
Biological Activities of Extracellular Vesicles and Their Cargos from Bovine and Human Milk in Humans and Implications for Infants. J Nutr (2016) 0.79
Plant microRNAs as novel immunomodulatory agents. Sci Rep (2016) 0.78
MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy. Cancers (Basel) (2015) 0.77
Anomalous uptake and circulatory characteristics of the plant-based small RNA MIR2911. Sci Rep (2016) 0.77
Sources and Functions of Extracellular Small RNAs in Human Circulation. Annu Rev Nutr (2016) 0.77
Negligible uptake and transfer of diet-derived pollen microRNAs in adult honey bees. RNA Biol (2016) 0.76
Nonfunctional ingestion of plant miRNAs in silkworm revealed by digital droplet PCR and transcriptome analysis. Sci Rep (2015) 0.76
Retracted Circulating plant miRNAs can regulate human gene expression in vitro. Sci Rep (2016) 0.76
miR156a Mimic Represses the Epithelial-Mesenchymal Transition of Human Nasopharyngeal Cancer Cells by Targeting Junctional Adhesion Molecule A. PLoS One (2016) 0.76
Milk exosomes: beyond dietary microRNAs. Genes Nutr (2017) 0.75
An improved method to quantitate mature plant microRNA in biological matrices using modified periodate treatment and inclusion of internal controls. PLoS One (2017) 0.75
The role of miRNAs in cardiovascular disease risk factors. Atherosclerosis (2016) 0.75
Digesting dietary miRNA therapeutics. Oncotarget (2015) 0.75
Exo-miRExplorer: A Comprehensive Resource for Exploring and Comparatively Analyzing Exogenous MicroRNAs. Front Microbiol (2017) 0.75
New Insight into Inter-kingdom Communication: Horizontal Transfer of Mobile Small RNAs. Front Microbiol (2017) 0.75
Plant MicroRNAs-Novel Players in Natural Medicine? Int J Mol Sci (2016) 0.75
Survey of 800+ datasets from human tissue and body fluid reveals XenomiRs are likely artifacts. RNA (2017) 0.75
Plant miRNAs found in human circulating system provide evidences of cross kingdom RNAi. BMC Genomics (2017) 0.75
Survival and Diversity of Human Homologous Dietary MicroRNAs in Conventionally Cooked Top Sirloin and Dried Bovine Tissue Extracts. PLoS One (2015) 0.75
Navigating dietary small RNAs. Genes Nutr (2017) 0.75
Diet-derived microRNAs: unicorn or silver bullet? Genes Nutr (2017) 0.75
Uptake and impact of natural diet-derived small RNA in invertebrates: Implications for ecology and agriculture. RNA Biol (2016) 0.75
Specific interference by ingested dsRNA. Nature (1998) 11.82
Methylation as a crucial step in plant microRNA biogenesis. Science (2005) 7.16
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA. Cell Res (2011) 4.55
Control of coleopteran insect pests through RNA interference. Nat Biotechnol (2007) 4.28
Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol. Nat Biotechnol (2007) 3.81
RNA-based therapeutics: current progress and future prospects. Chem Biol (2012) 3.01
RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. J Insect Physiol (2010) 2.47
Optimization of enzymatic reaction conditions for generating representative pools of cDNA from small RNA. RNA (2010) 1.74
Analysis of plant-derived miRNAs in animal small RNA datasets. BMC Genomics (2012) 1.52
Characterization of unique small RNA populations from rice grain. PLoS One (2008) 1.31
Evolution of susceptibility to ingested double-stranded RNAs in Caenorhabditis nematodes. PLoS One (2012) 1.23
Intestinal delivery of non-viral gene therapeutics: physiological barriers and preclinical models. Drug Discov Today (2011) 1.09
Endogenous small RNAs in grain: semi-quantification and sequence homology to human and animal genes. Food Chem Toxicol (2008) 0.99
Differential regulation of hepatic gene expression by starvation versus refeeding following a high-sucrose or high-fat diet. Nutrition (2005) 0.97
Oral delivery of small RNA and DNA. J Control Release (2012) 0.92
A 90-day toxicology study of high-amylose transgenic rice grain in Sprague-Dawley rats. Food Chem Toxicol (2011) 0.88
A three generation study with high-lysine transgenic rice in Sprague-Dawley rats. Food Chem Toxicol (2012) 0.84
Rational siRNA design for RNA interference. Nat Biotechnol (2004) 14.16
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
3' UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat Methods (2006) 6.96
Toward microRNA-based therapeutics for heart disease: the sense in antisense. Circ Res (2008) 3.18
Off-target effects by siRNA can induce toxic phenotype. RNA (2006) 2.89
The contributions of dsRNA structure to Dicer specificity and efficiency. RNA (2005) 2.48
Induction of the interferon response by siRNA is cell type- and duplex length-dependent. RNA (2006) 2.17
Double-stranded regions are essential design components of potent inhibitors of RISC function. RNA (2007) 1.83
Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics. Comp Biochem Physiol Part D Genomics Proteomics (2007) 1.52
Analysis of plant-derived miRNAs in animal small RNA datasets. BMC Genomics (2012) 1.52
Computational estimation and experimental verification of off-target silencing during posttranscriptional gene silencing in plants. Plant Physiol (2006) 1.43
Characterizing the mechanism of action of double-stranded RNA activity against western corn rootworm (Diabrotica virgifera virgifera LeConte). PLoS One (2012) 1.41
Tissue distribution and ontogeny of organic cation transporters in mice. Drug Metab Dispos (2005) 1.40
Characterization of unique small RNA populations from rice grain. PLoS One (2008) 1.31
Posttranscriptional gene silencing in nuclei. Proc Natl Acad Sci U S A (2010) 1.23
RNA oligonucleotide synthesis via 5'-silyl-2'-orthoester chemistry. Methods Mol Biol (2005) 1.11
Regulation of gene expression in plants through miRNA inactivation. PLoS One (2011) 1.11
Mechanistic insights aid computational short interfering RNA design. Methods Enzymol (2005) 1.09
Using small RNA sequences to diagnose, sequence, and investigate the infectivity characteristics of vegetable-infecting viruses. Arch Virol (2011) 1.02
Crystal structure of a luteoviral RNA pseudoknot and model for a minimal ribosomal frameshifting motif. Biochemistry (2005) 1.01
Endogenous small RNAs in grain: semi-quantification and sequence homology to human and animal genes. Food Chem Toxicol (2008) 0.99
Transcriptome profiling identified novel genes associated with aluminum toxicity, resistance and tolerance in Medicago truncatula. Planta (2008) 0.97
Recruitment of novel calcium-binding proteins for root nodule symbiosis in Medicago truncatula. Plant Physiol (2006) 0.95
Distinct Na+/K+/2Cl- cotransporter localization in kidneys and gills of two euryhaline species, rainbow trout and killifish. Cell Tissue Res (2008) 0.86
A novel real-time polymerase chain reaction method for high throughput quantification of small regulatory RNAs. Plant Biotechnol J (2009) 0.86
RNA decoys: an emerging component of plant regulatory networks? Plant Signal Behav (2012) 0.84
Preparation of 5'-silyl-2'-orthoester ribonucleosides for use in oligoribonucleotide synthesis. Curr Protoc Nucleic Acid Chem (2004) 0.82
A simple field test to assess endurance in inexperienced runners. J Strength Cond Res (2010) 0.81
Knockdown of CELL DIVISION CYCLE16 reveals an inverse relationship between lateral root and nodule numbers and a link to auxin in Medicago truncatula. Plant Physiol (2009) 0.81
Computational sequence analysis of predicted long dsRNA transcriptomes of major crops reveals sequence complementarity with human genes. GM Crops Food (2013) 0.78
Large-scale sequencing of plant small RNAs. Methods Mol Biol (2011) 0.78
The LCROSS cratering experiment. Science (2010) 0.77
Safety assessment considerations for food and feed derived from plants with genetic modifications that modulate endogenous gene expression and pathways. Food Chem Toxicol (2008) 0.76
Small RNA profiles from virus-infected fresh market vegetables. J Agric Food Chem (2014) 0.75