Published in Hepatology on March 01, 2014
Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity. Hepatology (2014) 2.23
Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice. Hepatology (2014) 2.17
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Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model. Am J Physiol Gastrointest Liver Physiol (2004) 1.86
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Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis. Toxicol Appl Pharmacol (2005) 1.31
Higher neutrophil infiltration mediated by osteopontin is a likely contributing factor to the increased susceptibility of females to alcoholic liver disease. J Pathol (2006) 1.31
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Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis. Hepatology (2013) 1.23
Thalidomide prevents alcoholic liver injury in rats through suppression of Kupffer cell sensitization and TNF-alpha production. Gastroenterology (2002) 1.20
The osteopontin level in liver, adipose tissue and serum is correlated with fibrosis in patients with alcoholic liver disease. PLoS One (2012) 1.17
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Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages. Biochim Biophys Acta (2012) 1.12
Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death. J Cell Physiol (2006) 1.06
Considerable variation in the concentration of osteopontin in human milk, bovine milk, and infant formulas. J Dairy Sci (2009) 1.02
Redox regulation of cytokine expression in Kupffer cells. Antioxid Redox Signal (2002) 0.98
Milk osteopontin, a nutritional approach to prevent alcohol-induced liver injury. Am J Physiol Gastrointest Liver Physiol (2013) 0.96
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Potential relationship between hepatobiliary osteopontin and peroxisome proliferator-activated receptor alpha expression following ethanol-associated hepatic injury in vivo and in vitro. Toxicol Sci (2008) 0.88
The influence of estrogen on hepatobiliary osteopontin (SPP1) expression in a female rodent model of alcoholic steatohepatitis. Toxicol Pathol (2009) 0.87
Interaction of osteopontin with neutrophil alpha(4)beta(1) and alpha(9)beta(1) integrins in a rodent model of alcoholic liver disease. Toxicol Appl Pharmacol (2008) 0.87
Differential effects of osteopontin on the cytotoxic activity of macrophages from young and old mice. Immunology (1996) 0.86
Transgenic mice expressing osteopontin in hepatocytes as a model of autoimmune hepatitis. Biochem Biophys Res Commun (2004) 0.82
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet (2009) 14.16
Role of oxidative stress in alcohol-induced liver injury. Arch Toxicol (2009) 2.45
Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues. Gastroenterology (2012) 2.11
Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity. J Biol Chem (2007) 2.03
A novel disulphide switch mechanism in Ero1alpha balances ER oxidation in human cells. EMBO J (2008) 1.97
Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications. Biochem J (2005) 1.69
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A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J (2004) 1.53
Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. Blood (2009) 1.53
Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches. Chem Biol Interact (2011) 1.44
Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. PLoS One (2012) 1.44
Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling. Hepatology (2012) 1.40
Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties. J Biol Chem (2007) 1.36
Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C. Hum Mol Genet (2011) 1.31
Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection. Cardiovasc Hematol Disord Drug Targets (2007) 1.25
Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression. Hepatology (2012) 1.24
Osteopontin is cleaved at multiple sites close to its integrin-binding motifs in milk and is a novel substrate for plasmin and cathepsin D. J Biol Chem (2010) 1.20
AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II. EMBO J (2011) 1.18
The presence of JAK2V617F mutation in the liver endothelial cells of patients with Budd-Chiari syndrome. Blood (2009) 1.13
Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy. J Hepatol (2013) 1.12
Virulent strain of hepatitis E virus genotype 3, Japan. Emerg Infect Dis (2009) 1.11
Therapeutic strategy for patients with bleeding rectal varices complicating liver cirrhosis. Hepatol Res (2014) 1.09
Binge ethanol exposure increases liver injury in obese rats. Gastroenterology (2003) 1.08
Post-translational modification and proteolytic processing of urinary osteopontin. Biochem J (2008) 1.08
Distinguishing of Ile/Leu amino acid residues in the PP3 protein by (hot) electron capture dissociation in Fourier transform ion cyclotron resonance mass spectrometry. Anal Chem (2003) 1.07
Plasma osteopontin levels in patients with fulminant hepatitis. Hepatol Res (2004) 1.07
Japanese herbal medicine Inchin-ko-to as a therapeutic drug for liver fibrosis. J Hepatol (2004) 1.07
Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response. J Biol Chem (2012) 1.06
Functional organization of the sortilin Vps10p domain. J Biol Chem (2004) 1.05
Complete characterization of posttranslational modification sites in the bovine milk protein PP3 by tandem mass spectrometry with electron capture dissociation as the last stage. Anal Chem (2003) 1.05
Osteopontin enhances phagocytosis through a novel osteopontin receptor, the alphaXbeta2 integrin. J Immunol (2009) 1.04
T cell targeting and phagocytosis of apoptotic biliary epithelial cells in primary biliary cirrhosis. J Autoimmun (2007) 1.03
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Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease. Am J Physiol Gastrointest Liver Physiol (2013) 1.01
Risk for immune-mediated graft dysfunction in liver transplant recipients with recurrent HCV infection treated with pegylated interferon. Gastroenterology (2012) 1.01
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Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice. Hepatology (2005) 0.98
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Alcohol and liver fibrosis. Semin Liver Dis (2009) 0.98
Milk osteopontin, a nutritional approach to prevent alcohol-induced liver injury. Am J Physiol Gastrointest Liver Physiol (2013) 0.96
Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development. Int J Cancer (2014) 0.95
SNPs in the promoter region of the osteopontin gene as a marker predicting the efficacy of interferon-based therapies in patients with chronic hepatitis C. J Gastroenterol (2005) 0.95
Role of calcium phosphate nanoclusters in the control of calcification. FEBS J (2009) 0.94
No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations. BMC Med Genet (2012) 0.94
Osteopontin attenuation of dextran sulfate sodium-induced colitis in mice. Lab Invest (2009) 0.93
Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients. J Interferon Cytokine Res (2010) 0.92
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Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes. Alcohol Clin Exp Res (2011) 0.91
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Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. J Biol Chem (2003) 0.90
A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection. Antivir Ther (2014) 0.90
C-terminal modification of osteopontin inhibits interaction with the αVβ3-integrin. J Biol Chem (2011) 0.89
Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha. Gastroenterology (2009) 0.89
Osteopontin delays resolution of liver fibrosis. Lab Invest (2013) 0.88
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Fulminant hepatic failure attributed to ackee fruit ingestion in a patient with sickle cell trait. Case Rep Transplant (2012) 0.87
ERK/MAPK-dependent PI3K/Akt phosphorylation through VEGFR-1 after VEGF stimulation in activated hepatic stellate cells. Hepatol Res (2003) 0.87
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Impact of donor age on survival and fibrosis progression in patients with hepatitis C undergoing liver transplantation using HCV+ allografts. Liver Transpl (2006) 0.87
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Algorithm to determine the outcome of patients with acute liver failure: a data-mining analysis using decision trees. J Gastroenterol (2012) 0.86
Splicing regulator SLU7 is essential for maintaining liver homeostasis. J Clin Invest (2014) 0.86
A voluntary oral-feeding rat model for pathological alcoholic liver injury. Methods Mol Biol (2008) 0.86
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Massive liver necrosis after provocation of imbalance between Th1 and Th2 immune reactions in osteopontin transgenic mice. J Gastroenterol (2004) 0.86
Novel classification of acute liver failure through clustering using a self-organizing map: usefulness for prediction of the outcome. J Gastroenterol (2011) 0.85
Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system. PLoS One (2012) 0.85
Transcatheter arterial chemoembolization for hepatocellular carcinoma: Comparison of the therapeutic efficacies between miriplatin and epirubicin. Hepatol Res (2013) 0.85
Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin. Protein Sci (2014) 0.85
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Angiopoietin/tie receptors system may play a role during reconstruction and capillarization of the hepatic sinusoids after partial hepatectomy and liver necrosis in rats. Hepatol Res (2004) 0.85
Cu/Zn superoxide dismutase (SOD1) induction is implicated in the antioxidative and antiviral activity of acetylsalicylic acid in HCV-expressing cells. Am J Physiol Gastrointest Liver Physiol (2012) 0.84
Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice. PLoS One (2010) 0.84
Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage. ACS Nano (2013) 0.84
Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells. Biochim Biophys Acta (2007) 0.84
Crystallization of calcium oxalates is controlled by molecular hydrophilicity and specific polyanion-crystal interactions. Langmuir (2009) 0.84
Role of phosphate groups in inhibition of calcium oxalate crystal growth by osteopontin. Cells Tissues Organs (2008) 0.84
Drug-induced immunoallergic hepatitis during combination therapy with daclatasvir and asunaprevir. Hepatology (2014) 0.84
Cooperation of phosphates and carboxylates controls calcium oxalate crystallization in ultrafiltered urine. Urol Res (2011) 0.83
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Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair. Liver Int (2013) 0.83
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