Published in J Cell Biol on May 01, 1986
gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans. Genetics (1995) 2.94
Analysis of the multiple roles of gld-1 in germline development: interactions with the sex determination cascade and the glp-1 signaling pathway. Genetics (1995) 2.04
CPEB proteins control two key steps in spermatogenesis in C. elegans. Genes Dev (2000) 1.61
An isoform of eIF4E is a component of germ granules and is required for spermatogenesis in C. elegans. Development (2001) 1.53
EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans. Mol Biol Cell (2000) 1.52
Membrane and cytoplasmic proteins are transported in the same organelle complex during nematode spermatogenesis. J Cell Biol (1986) 1.47
LIP-1 phosphatase controls the extent of germline proliferation in Caenorhabditis elegans. EMBO J (2005) 1.40
Dose-dependent control of proliferation and sperm specification by FOG-1/CPEB. Development (2005) 1.38
The Caenorhabditis elegans THO complex is required for the mitotic cell cycle and development. PLoS One (2012) 1.38
The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans. Genetics (1993) 1.33
A Caenorhabditis elegans RNA-directed RNA polymerase in sperm development and endogenous RNA interference. Genetics (2009) 1.28
A unique cytoskeleton associated with crawling in the amoeboid sperm of the nematode, Ascaris suum. J Cell Biol (1989) 1.25
Redundant control of the Caenorhabditis elegans sperm/oocyte switch by PUF-8 and FBF-1, two distinct PUF RNA-binding proteins. Proc Natl Acad Sci U S A (2005) 1.22
The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans. Genes Dev (2004) 1.20
A monoclonal antibody toolkit for C. elegans. PLoS One (2010) 1.19
Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions. J Cell Biol (1992) 1.16
Antagonism between GLD-2 binding partners controls gamete sex. Dev Cell (2009) 1.10
C. elegans RNA-binding proteins PUF-8 and MEX-3 function redundantly to promote germline stem cell mitosis. Dev Biol (2008) 1.10
Developmental expression of FOG-1/CPEB protein and its control in the Caenorhabditis elegans hermaphrodite germ line. Dev Dyn (2007) 0.97
Sperm development and motility are regulated by PP1 phosphatases in Caenorhabditis elegans. Genetics (2011) 0.93
A new dataset of spermatogenic vs. oogenic transcriptomes in the nematode Caenorhabditis elegans. G3 (Bethesda) (2014) 0.91
Guidelines for monitoring autophagy in Caenorhabditis elegans. Autophagy (2015) 0.91
CSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline. Development (2015) 0.89
GLS-1, a novel P granule component, modulates a network of conserved RNA regulators to influence germ cell fate decisions. PLoS Genet (2009) 0.88
Mitosis-meiosis and sperm-oocyte fate decisions are separable regulatory events. Proc Natl Acad Sci U S A (2013) 0.86
Characterization of a monoclonal antibody that induces the acrosome reaction of sea urchin sperm. J Cell Biol (1987) 0.83
PAB-1, a Caenorhabditis elegans poly(A)-binding protein, regulates mRNA metabolism in germline by interacting with CGH-1 and CAR-1. PLoS One (2013) 0.79
Mutual antagonism between the anaphase promoting complex and the spindle assembly checkpoint contributes to mitotic timing in Caenorhabditis elegans. Genetics (2010) 0.78
The sperm-oocyte switch in the C. elegans hermaphrodite is controlled through steady-state levels of the fem-3 mRNA. RNA (2012) 0.78
Competence for chemical reprogramming of sexual fate correlates with an intersexual molecular signature in Caenorhabditis elegans. Genetics (2014) 0.75
PUF-8 Functions Redundantly with GLD-1 to Promote the Meiotic Progression of Spermatocytes in Caenorhabditis elegans. G3 (Bethesda) (2015) 0.75
Approaches for Studying Autophagy in Caenorhabditis elegans. Cells (2017) 0.75
MPK-1/ERK regulatory network controls the number of sperm by regulating timing of sperm-oocyte switch in C. elegans germline. Biochem Biophys Res Commun (2017) 0.75
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51
Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. Biochemistry (1971) 66.90
Maturation of the head of bacteriophage T4. I. DNA packaging events. J Mol Biol (1973) 33.51
A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. J Immunol (1979) 16.56
The structure of an antigenic determinant in a protein. Cell (1984) 10.85
Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS. Genetics (1979) 10.54
X-ray intensifying screens greatly enhance the detection by autoradiography of the radioactive isotopes 32P and 125I. Anal Biochem (1978) 10.28
Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3alpha,6alpha-diphenylglycoluril. Biochemistry (1978) 9.04
A one-step purification of membrane proteins using a high efficiency immunomatrix. J Biol Chem (1982) 6.70
Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes. J Biol Chem (1982) 5.87
The antigenic structure of proteins: a reappraisal. Annu Rev Immunol (1984) 5.31
The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein. Nature (1984) 4.05
Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. Nature (1985) 3.68
Correlation between segmental mobility and the location of antigenic determinants in proteins. Nature (1984) 3.66
Hybrid cell lines secreting monoclonal antibody specific for major histocompatibility antigens of the mouse. Nature (1978) 3.45
Demonstration of peptide:N-glycosidase F activity in endo-beta-N-acetylglucosaminidase F preparations. J Biol Chem (1984) 3.26
Characterization of temperature-sensitive, fertilization-defective mutants of the nematode caenorhabditis elegans. Genetics (1978) 2.68
Intersex, a temperature-sensitive mutant of the nematode Caenorhabditis elegans. Dev Biol (1978) 2.62
Prevention of NH2-terminal acetylation of proteins synthesized in cell-free systems. J Biol Chem (1977) 2.38
Molecular recognition and the future of monoclonal antibodies. Nature (1982) 2.22
Sperm morphogenesis in wild-type and fertilization-defective mutants of Caenorhabditis elegans. J Cell Biol (1981) 2.18
Molecular mimicry in virus infection: crossreaction of measles virus phosphoprotein or of herpes simplex virus protein with human intermediate filaments. Proc Natl Acad Sci U S A (1983) 2.12
The initiation of spermiogenesis in the nematode Caenorhabditis elegans. Dev Biol (1983) 1.89
Nascent chicken ovalbumin contains the functional equivalent of a signal sequence. J Cell Biol (1978) 1.88
Temperature-sensitive zygote defective mutants of Caenorhabditis elegans. Dev Biol (1976) 1.72
Caenorhabditis elegans spermatozoan locomotion: amoeboid movement with almost no actin. J Cell Biol (1982) 1.66
Multiple organ-reactive monoclonal autoantibodies. Nature (1983) 1.64
Isolation and characterization of a sperm-specific gene family in the nematode Caenorhabditis elegans. Mol Cell Biol (1984) 1.54
Membrane and cytoplasmic proteins are transported in the same organelle complex during nematode spermatogenesis. J Cell Biol (1986) 1.47
Caenorhabditis elegans fertilization-defective mutants with abnormal sperm. Genetics (1980) 1.47
Multiple forms of (Na+ + K+)-ATPase in the chicken. Selective detection of the major nerve, skeletal muscle, and kidney form by a monoclonal antibody. J Biol Chem (1983) 1.29
Membrane flow during nematode spermiogenesis. J Cell Biol (1982) 1.27
Antigenic determinants shared by lysosomal proteins of Dictyostelium discoideum. Characterization using monoclonal antibodies and isolation of mutations affecting the determinant. J Biol Chem (1984) 1.18
Identification of a large multigene family encoding the major sperm protein of Caenorhabditis elegans. J Mol Biol (1983) 1.08
The location of the major protein in Caenorhabditis elegans sperm and spermatocytes. Dev Biol (1982) 1.08
The use of monoclonal antibody techniques in the study of development cell surfaces. Curr Top Dev Biol (1980) 1.08
Isolation and characterization of monoclonal antibodies to structural and nonstructural herpesvirus saimiri proteins. J Virol (1984) 1.07
Centripetal flow of pseudopodial surface components could propel the amoeboid movement of Caenorhabditis elegans spermatozoa. J Cell Biol (1982) 1.02
Monoclonal antibody recognizing gp80, a membrane glycoprotein implicated in intercellular adhesion of Dictyostelium discoideum. Mol Cell Biol (1983) 0.97
Cell-specific transcriptional regulation of the major sperm protein in Caenorhabditis elegans. Dev Biol (1982) 0.90
Membrane-substrate contact under the spermatozoon of Caenorhabditis elegans, a crawling cell that lacks filamentous actin. J Cell Sci (1984) 0.89
Serologic relatedness between Thy-1.2 and actin revealed by monoclonal antibody. J Immunol (1983) 0.89
The identification of a VH subgroup allotypic specificity, y30, which differentiates the y33 allele into two variants. Implications for rabbit VH gene organization and evolution. Mol Immunol (1981) 0.81
The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest (2000) 9.51
Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest (1999) 7.40
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature (1985) 7.10
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro. Science (1992) 6.80
How the lambda repressor and cro work. Cell (1980) 6.65
Electron microscopical reconstruction of the anterior sensory anatomy of the nematode Caenorhabditis elegans.?2UU. J Comp Neurol (1975) 6.58
Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit beta-globin. Cell (1980) 6.20
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell (1990) 6.12
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science (1997) 6.10
A global profile of germline gene expression in C. elegans. Mol Cell (2000) 5.97
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell (1987) 5.87
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src. Cell (1987) 5.84
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell (1992) 5.77
An interaction between alpha-actinin and the beta 1 integrin subunit in vitro. J Cell Biol (1990) 5.66
Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell (1989) 4.86
Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants. Proc Natl Acad Sci U S A (1973) 4.76
Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. Cell (1987) 4.70
Chromosome condensation and sister chromatid pairing in budding yeast. J Cell Biol (1994) 4.47
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci U S A (1999) 4.19
Presence of an SH2 domain in the actin-binding protein tensin. Science (1991) 4.03
Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos. Cell (1983) 4.01
SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. Genes Dev (1995) 3.88
Fertilization and sperm competition in the nematode Caenorhabditis elegans. Dev Biol (1979) 3.78
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase. Science (1997) 3.73
Characterization of a germ-line proliferation mutation in C. elegans. Development (1992) 3.70
An investigation into the effectiveness of an early intervention method for delayed language development in young children. Int J Lang Commun Disord (2000) 3.68
A general method for maximizing the expression of a cloned gene. Proc Natl Acad Sci U S A (1979) 3.67
Earliest Homo. Nature (1992) 3.52
Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. Proc Natl Acad Sci U S A (1988) 3.52
lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Cell (1987) 3.33
Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cells. Cell (1988) 3.29
Oncogenes, growth factors, and signal transduction. N Engl J Med (1989) 3.18
PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans. Cell (1998) 3.07
Synapsis and chiasma formation in Caenorhabditis elegans require HIM-3, a meiotic chromosome core component that functions in chromosome segregation. Genes Dev (1999) 2.86
Sequence of Cro gene of bacteriophage lambda. Nature (1977) 2.78
Interaction of the protein kinase Raf-1 with 14-3-3 proteins. Science (1994) 2.74
Characterization of temperature-sensitive, fertilization-defective mutants of the nematode caenorhabditis elegans. Genetics (1978) 2.68
Determination of the nuclear DNA content of Saccharomyces cerevisiae and implications for the organization of DNA in yeast chromosomes. J Mol Biol (1977) 2.67
Intersex, a temperature-sensitive mutant of the nematode Caenorhabditis elegans. Dev Biol (1978) 2.62
Phosphatidylinositol metabolism and polyoma-mediated transformation. Proc Natl Acad Sci U S A (1986) 2.62
A nematode kinesin required for cleavage furrow advancement. Curr Biol (1998) 2.36
Experience with a clinical guideline for the treatment of ventilator-associated pneumonia. Crit Care Med (2001) 2.35
Isolation of ras GTP-binding mutants using an in situ colony-binding assay. Proc Natl Acad Sci U S A (1986) 2.35
Larger sperm outcompete smaller sperm in the nematode Caenorhabditis elegans. Proc Biol Sci (1998) 2.35
Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants. Infect Immun (1990) 2.32
Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production. J Virol (1986) 2.27
Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans. Proc Natl Acad Sci U S A (1982) 2.25
Heterogeneous mutations in the beta subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency. Cell (1987) 2.23
Sperm morphogenesis in wild-type and fertilization-defective mutants of Caenorhabditis elegans. J Cell Biol (1981) 2.18
Evaluation of an inspiratory muscle trainer in healthy humans. Respir Med (2001) 2.16
The influence of mini-BAL cultures on patient outcomes: implications for the antibiotic management of ventilator-associated pneumonia. Chest (1998) 2.15
Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration. Trans R Soc Trop Med Hyg (1993) 2.15
Vesicle fusion, pseudopod extension and amoeboid motility are induced in nematode spermatids by the ionophore monensin. Cell (1980) 2.09
A plasmid cloning vehicle allowing a positive selection for inserted fragments. Gene (1980) 2.08
DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication. Genes Dev (1997) 2.06
Fitness to practise: Unbelievably arrogant. Br Dent J (2014) 2.03
Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol Cell Biol (1997) 2.01
Developmental genetics of chromosome I spermatogenesis-defective mutants in the nematode Caenorhabditis elegans. Genetics (1988) 2.01
MES-2, a maternal protein essential for viability of the germline in Caenorhabditis elegans, is homologous to a Drosophila Polycomb group protein. Development (1998) 1.97
Asthma Control Questionnaire in children: validation, measurement properties, interpretation. Eur Respir J (2010) 1.97
The Polycomb group in Caenorhabditis elegans and maternal control of germline development. Development (1998) 1.97
Multiple potential germ-line helicases are components of the germ-line-specific P granules of Caenorhabditis elegans. Proc Natl Acad Sci U S A (1996) 1.95
Plants and soils as indicators of metals in the air. Nature (1971) 1.94
Centromere position in budding yeast: evidence for anaphase A. Mol Biol Cell (1997) 1.93
Cell biology. A signal chain of events. Nature (1992) 1.93
The CDC20 gene product of Saccharomyces cerevisiae, a beta-transducin homolog, is required for a subset of microtubule-dependent cellular processes. Mol Cell Biol (1991) 1.92
Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase. Proc Natl Acad Sci U S A (1992) 1.91
An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase. J Virol (1991) 1.90
The initiation of spermiogenesis in the nematode Caenorhabditis elegans. Dev Biol (1983) 1.89
Same/different concept learning in the pigeon: the effect of negative instances and prior adaptation to transfer stimuli. J Exp Anal Behav (1978) 1.86
Fluorescence visualization of the distribution of microfilaments in gonads and early embryos of the nematode Caenorhabditis elegans. J Cell Biol (1986) 1.85
Expression of the human fibroblast interferon gene in Escherichia coli. Proc Natl Acad Sci U S A (1980) 1.84
Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice. Proc Natl Acad Sci U S A (2000) 1.83
Identification of grandchildless loci whose products are required for normal germ-line development in the nematode Caenorhabditis elegans. Genetics (1991) 1.81
Stability of plasma concentrations of N and C terminal atrial natriuretic peptides at room temperature. Heart (1996) 1.79
Maximizing gene expression on a plasmid using recombination in vitro. Methods Enzymol (1979) 1.78
Cellular proteins that associate with the middle and small T antigens of polyomavirus. J Virol (1988) 1.78
An analysis of the role of microfilaments in the establishment and maintenance of asymmetry in Caenorhabditis elegans zygotes. Dev Biol (1988) 1.77
The influence of access to a private attending physician on the withdrawal of life-sustaining therapies in the intensive care unit. Crit Care Med (1999) 1.77
Recombinant retroviruses that transduce individual polyoma tumor antigens: effects on growth and differentiation. Proc Natl Acad Sci U S A (1986) 1.75
Methods for fractionation and scintillation counting of radioisotope-labeled polyacrylamide gels. Anal Biochem (1970) 1.74
Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin. J Biol Chem (1998) 1.74
Evolution of sperm size in nematodes: sperm competition favours larger sperm. Proc Biol Sci (1999) 1.73
Launching the germline in Caenorhabditis elegans: regulation of gene expression in early germ cells. Development (1999) 1.73
Synthesis of simian virus 40 t antigen in Escherichia coli. Proc Natl Acad Sci U S A (1979) 1.70
ENCORE: the effect of nutrient enrichment on coral reefs. Synthesis of results and conclusions. Mar Pollut Bull (2001) 1.69
A representational approach to patient education. J Nurs Scholarsh (2001) 1.68
Blockade of kit signaling induces transdifferentiation of interstitial cells of cajal to a smooth muscle phenotype. Gastroenterology (1999) 1.67
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Caenorhabditis elegans spermatozoan locomotion: amoeboid movement with almost no actin. J Cell Biol (1982) 1.66
The impact of the introduction of a rapid D-dimer assay on the diagnostic evaluation of suspected pulmonary embolism. Arch Intern Med (2001) 1.65
Molecular characterization of the surface layer proteins from Clostridium difficile. Mol Microbiol (2001) 1.65
The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction. Proc Natl Acad Sci U S A (1993) 1.63
A nematode gene required for sperm vesicle fusion. J Cell Sci (1997) 1.62
Purification of biologically active simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A (1983) 1.61
Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc Natl Acad Sci U S A (1999) 1.60
Ca(2+) regulates fluid shear-induced cytoskeletal reorganization and gene expression in osteoblasts. Am J Physiol Cell Physiol (2000) 1.59
Sperm precedence in a hermaphroditic nematode (Caenorhabditis elegans) is due to competitive superiority of male sperm. Experientia (1995) 1.58