PubRank

Stefan W Hell

Author PubWeight™ 238.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins. Proc Natl Acad Sci U S A 2005 6.65
2 STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis. Nature 2006 6.54
3 Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature 2008 6.38
4 Video-rate far-field optical nanoscopy dissects synaptic vesicle movement. Science 2008 5.87
5 Bruchpilot promotes active zone assembly, Ca2+ channel clustering, and vesicle release. Science 2006 5.39
6 Fluorescence nanoscopy by ground-state depletion and single-molecule return. Nat Methods 2008 4.69
7 Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters. Biophys J 2007 3.93
8 Anatomy and dynamics of a supramolecular membrane protein cluster. Science 2007 3.75
9 Nanoscale resolution in the focal plane of an optical microscope. Phys Rev Lett 2005 3.60
10 Spherical nanosized focal spot unravels the interior of cells. Nat Methods 2008 3.43
11 Nanoscale resolution in GFP-based microscopy. Nat Methods 2006 3.19
12 Macromolecular-scale resolution in biological fluorescence microscopy. Proc Natl Acad Sci U S A 2006 3.04
13 STED microscopy with continuous wave beams. Nat Methods 2007 2.62
14 Diffraction-unlimited all-optical imaging and writing with a photochromic GFP. Nature 2011 2.56
15 Live-cell imaging of dendritic spines by STED microscopy. Proc Natl Acad Sci U S A 2008 2.53
16 Two-color far-field fluorescence nanoscopy. Biophys J 2007 2.44
17 Membrane protein sequestering by ionic protein-lipid interactions. Nature 2011 2.40
18 Stimulated emission depletion (STED) nanoscopy of a fluorescent protein-labeled organelle inside a living cell. Proc Natl Acad Sci U S A 2008 2.36
19 Protein localization in electron micrographs using fluorescence nanoscopy. Nat Methods 2010 2.33
20 1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants. Biochem J 2007 2.33
21 Tuning of synapse number, structure and function in the cochlea. Nat Neurosci 2009 2.29
22 Two-color nanoscopy of three-dimensional volumes by 4Pi detection of stochastically switched fluorophores. Nat Methods 2011 2.28
23 2,2'-thiodiethanol: a new water soluble mounting medium for high resolution optical microscopy. Microsc Res Tech 2007 2.23
24 Structure and mechanism of the reversible photoswitch of a fluorescent protein. Proc Natl Acad Sci U S A 2005 2.21
25 Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast. Proc Natl Acad Sci U S A 2002 2.19
26 Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids. Proc Natl Acad Sci U S A 2010 2.14
27 A rapidly maturing far-red derivative of DsRed-Express2 for whole-cell labeling. Biochemistry 2009 2.12
28 Structural basis for reversible photoswitching in Dronpa. Proc Natl Acad Sci U S A 2007 2.08
29 Major signal increase in fluorescence microscopy through dark-state relaxation. Nat Methods 2006 2.08
30 Focal spots of size lambda/23 open up far-field fluorescence microscopy at 33 nm axial resolution. Phys Rev Lett 2002 2.06
31 The SNARE motif is essential for the formation of syntaxin clusters in the plasma membrane. Biophys J 2006 2.04
32 Fluorescence microscopy with super-resolved optical sections. Trends Cell Biol 2005 2.00
33 Resolution scaling in STED microscopy. Opt Express 2008 1.89
34 Sharper low-power STED nanoscopy by time gating. Nat Methods 2011 1.87
35 Two-photon excitation STED microscopy. Opt Express 2009 1.81
36 Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy. Nat Biotechnol 2008 1.80
37 Nanoscopy in a living mouse brain. Science 2012 1.80
38 Multicolor fluorescence nanoscopy in fixed and living cells by exciting conventional fluorophores with a single wavelength. Biophys J 2010 1.74
39 A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat Biotechnol 2011 1.74
40 STED nanoscopy of actin dynamics in synapses deep inside living brain slices. Biophys J 2011 1.67
41 Generation of monomeric reversibly switchable red fluorescent proteins for far-field fluorescence nanoscopy. Biophys J 2008 1.67
42 Molecular orientation affects localization accuracy in superresolution far-field fluorescence microscopy. Nano Lett 2010 1.64
43 rsEGFP2 enables fast RESOLFT nanoscopy of living cells. Elife 2012 1.61
44 Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals. Proc Natl Acad Sci U S A 2007 1.59
45 Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons. J Neurosci 2008 1.59
46 RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release. Science 2011 1.59
47 Wide-field subdiffraction RESOLFT microscopy using fluorescent protein photoswitching. Microsc Res Tech 2007 1.58
48 STED microscopy with a supercontinuum laser source. Opt Express 2008 1.55
49 Breaking the diffraction barrier in fluorescence microscopy by optical shelving. Phys Rev Lett 2007 1.53
50 Stimulated emission depletion nanoscopy of living cells using SNAP-tag fusion proteins. Biophys J 2010 1.52
51 Maturation-dependent HIV-1 surface protein redistribution revealed by fluorescence nanoscopy. Science 2012 1.50
52 4Pi-microscopy of the Golgi apparatus in live mammalian cells. J Struct Biol 2004 1.50
53 Photostability of a fluorescent marker under pulsed excited-state depletion through stimulated emission. Appl Opt 2003 1.49
54 Fluorescence fluctuation spectroscopy in subdiffraction focal volumes. Phys Rev Lett 2005 1.48
55 Nanoscopy with more than 100,000 'doughnuts'. Nat Methods 2013 1.48
56 Stimulated emission depletion live-cell super-resolution imaging shows proliferative remodeling of T-tubule membrane structures after myocardial infarction. Circ Res 2012 1.47
57 Coaligned dual-channel STED nanoscopy and molecular diffusion analysis at 20 nm resolution. Biophys J 2013 1.46
58 Multicolor far-field fluorescence nanoscopy through isolated detection of distinct molecular species. Nano Lett 2008 1.46
59 Block copolymer nanostructures mapped by far-field optics. Nano Lett 2009 1.45
60 Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane. Mol Syst Biol 2011 1.44
61 Simultaneous multi-lifetime multi-color STED imaging for colocalization analyses. Opt Express 2011 1.44
62 Isotropic 3D Nanoscopy based on single emitter switching. Opt Express 2008 1.40
63 Fluorescence nanoscopy with optical sectioning by two-photon induced molecular switching using continuous-wave lasers. Chemphyschem 2008 1.39
64 Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment. Nat Struct Mol Biol 2013 1.38
65 Immunofluorescence stimulated emission depletion microscopy. Nat Biotechnol 2003 1.38
66 Red-emitting rhodamine dyes for fluorescence microscopy and nanoscopy. Chemistry 2010 1.37
67 Spatial and temporal dynamics of budding yeast mitochondria lacking the division component Fis1p. J Cell Sci 2003 1.35
68 Nanoscopy of living brain slices with low light levels. Neuron 2012 1.35
69 Mitochondrial cristae revealed with focused light. Nano Lett 2009 1.32
70 Endosomal sorting of readily releasable synaptic vesicles. Proc Natl Acad Sci U S A 2010 1.31
71 Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient. Proc Natl Acad Sci U S A 2011 1.27
72 3D reconstruction of high-resolution STED microscope images. Microsc Res Tech 2008 1.26
73 A readily retrievable pool of synaptic vesicles. Nat Neurosci 2011 1.24
74 Fast STED microscopy with continuous wave fiber lasers. Opt Express 2010 1.22
75 Dual-color STED microscopy at 30-nm focal-plane resolution. Small 2008 1.20
76 STED nanoscopy with time-gated detection: theoretical and experimental aspects. PLoS One 2013 1.20
77 Enhancing fluorescence brightness: effect of reverse intersystem crossing studied by fluorescence fluctuation spectroscopy. Chemphyschem 2008 1.20
78 Three-dimensional nanoscopy of colloidal crystals. Nano Lett 2008 1.17
79 Nanoscopy in a living multicellular organism expressing GFP. Biophys J 2011 1.16
80 STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA. Nat Methods 2013 1.15
81 STED microscopy detects and quantifies liquid phase separation in lipid membranes using a new far-red emitting fluorescent phosphoglycerolipid analogue. Faraday Discuss 2013 1.14
82 Cooperative 4Pi excitation and detection yields sevenfold sharper optical sections in live-cell microscopy. Biophys J 2004 1.12
83 Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis. J Neurosci 2011 1.11
84 Efficient fluorescence inhibition patterns for RESOLFT microscopy. Opt Express 2007 1.11
85 Drift estimation for single marker switching based imaging schemes. Opt Express 2012 1.11
86 Single-molecule STED microscopy with photostable organic fluorophores. Small 2010 1.10
87 Limited intermixing of synaptic vesicle components upon vesicle recycling. Traffic 2010 1.10
88 Spectroscopic rationale for efficient stimulated-emission depletion microscopy fluorophores. J Am Chem Soc 2010 1.10
89 Rhodamines NN: a novel class of caged fluorescent dyes. Angew Chem Int Ed Engl 2010 1.09
90 Three-dimensional organization of promyelocytic leukemia nuclear bodies. J Cell Sci 2010 1.09
91 Parallelized STED fluorescence nanoscopy. Opt Express 2011 1.09
92 A lipid bound actin meshwork organizes liquid phase separation in model membranes. Elife 2014 1.08
93 Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin. EMBO J 2006 1.07
94 Three-dimensional stimulated emission depletion microscopy of nitrogen-vacancy centers in diamond using continuous-wave light. Nano Lett 2009 1.06
95 An overexpression screen of Toxoplasma gondii Rab-GTPases reveals distinct transport routes to the micronemes. PLoS Pathog 2013 1.05
96 Analytical description of STED microscopy performance. Opt Express 2010 1.04
97 Fluorescence resonance energy transfer analysis of protein-protein interactions in single living cells by multifocal multiphoton microscopy. J Biotechnol 2002 1.03
98 Quantum dot blueing and blinking enables fluorescence nanoscopy. Nano Lett 2010 1.03
99 Triplet-relaxation microscopy with bunched pulsed excitation. Photochem Photobiol Sci 2009 1.02
100 Photoconversion of matrix targeted GFP enables analysis of continuity and intermixing of the mitochondrial lumen. FEBS Lett 2003 1.02
101 Nanoscale engineering and optical addressing of single spins in diamond. Small 2010 1.01
102 Two-color STED microscopy reveals different degrees of colocalization between hexokinase-I and the three human VDAC isoforms. PMC Biophys 2010 1.01
103 Solid immersion facilitates fluorescence microscopy with nanometer resolution and sub-ångström emitter localization. Adv Mater 2012 1.00
104 Dual-label STED nanoscopy of living cells using photochromism. Nano Lett 2011 1.00
105 Regulation of endothelial barrier function during flow-induced conversion to an arterial phenotype. Cardiovasc Res 2007 0.99
106 Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J Biol Chem 2010 0.99
107 Diffraction unlimited all-optical recording of electron spin resonances. Phys Rev Lett 2011 0.99
108 New fluorinated rhodamines for optical microscopy and nanoscopy. Chemistry 2010 0.98
109 Rhodamine spiroamides for multicolor single-molecule switching fluorescent nanoscopy. Chemistry 2009 0.98
110 Munc18-1 tuning of vesicle merger and fusion pore properties. J Neurosci 2011 0.97
111 Comparing video-rate STED nanoscopy and confocal microscopy of living neurons. J Biophotonics 2010 0.96
112 Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity. J Neurosci 2012 0.95
113 Reversible red fluorescent molecular switches. Angew Chem Int Ed Engl 2006 0.95
114 STED with wavelengths closer to the emission maximum. Opt Express 2012 0.95
115 Nanoscale separation of molecular species based on their rotational mobility. Opt Express 2008 0.95
116 Microscopy: Light from the dark. Nature 2009 0.94
117 Metastable dark States enable ground state depletion microscopy of nitrogen vacancy centers in diamond with diffraction-unlimited resolution. Nano Lett 2010 0.94
118 The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles. J Cell Biol 2013 0.93
119 Birefringent device converts a standard scanning microscope into a STED microscope that also maps molecular orientation. Opt Express 2010 0.93
120 Novel roles of Caenorhabditis elegans heterochromatin protein HP1 and linker histone in the regulation of innate immune gene expression. Mol Cell Biol 2011 0.91
121 Fluorescence nanoscopy goes multicolor. Nat Biotechnol 2007 0.90
122 STED nanoscopy with mass-produced laser diodes. Opt Express 2011 0.89
123 Direct light-driven modulation of luminescence from Mn-doped ZnSe quantum dots. Angew Chem Int Ed Engl 2008 0.89
124 Two-color RESOLFT nanoscopy with green and red fluorescent photochromic proteins. Chemphyschem 2014 0.88
125 Dynamic imaging of colloidal-crystal nanostructures at 200 frames per second. Langmuir 2010 0.88
126 High- and low-mobility stages in the synaptic vesicle cycle. Biophys J 2010 0.88
127 Photostable, amino reactive and water-soluble fluorescent labels based on sulfonated rhodamine with a rigidized xanthene fragment. Chemistry 2008 0.88
128 Stimulated emission depletion microscopy resolves individual nitrogen vacancy centers in diamond nanocrystals. ACS Nano 2013 0.87
129 A STED microscope aligned by design. Opt Express 2009 0.87
130 Synthesis and characterization of photoswitchable fluorescent silica nanoparticles. Small 2008 0.87
131 Masked rhodamine dyes of five principal colors revealed by photolysis of a 2-diazo-1-indanone caging group: synthesis, photophysics, and light microscopy applications. Chemistry 2014 0.87
132 Far-field autofluorescence nanoscopy. Nano Lett 2010 0.86
133 Dual channel RESOLFT nanoscopy by using fluorescent state kinetics. Nano Lett 2014 0.86
134 Polar red-emitting rhodamine dyes with reactive groups: synthesis, photophysical properties, and two-color STED nanoscopy applications. Chemistry 2013 0.86
135 2000-fold parallelized dual-color STED fluorescence nanoscopy. Opt Express 2015 0.84
136 Fluorescence correlation spectroscopy with a total internal reflection fluorescence STED microscope (TIRF-STED-FCS). Opt Express 2012 0.84
137 Phosphorylated 3-heteroarylcoumarins and their use in fluorescence microscopy and nanoscopy. Chemistry 2012 0.84
138 Calculation of vectorial three-dimensional transfer functions in large-angle focusing systems. J Opt Soc Am A Opt Image Sci Vis 2002 0.83
139 Coordinate-targeted and coordinate-stochastic super-resolution microscopy with the reversibly switchable fluorescent protein Dreiklang. Chemphyschem 2014 0.82
140 Fluorescence nanoscopy of single DNA molecules by using stimulated emission depletion (STED). Angew Chem Int Ed Engl 2011 0.82
141 Red-emitting rhodamines with hydroxylated, sulfonated, and phosphorylated dye residues and their use in fluorescence nanoscopy. Chemistry 2012 0.82
142 MRT letter: Nanoscopy of protein colocalization in living cells by STED and GSDIM. Microsc Res Tech 2011 0.82
143 Far-field optical nanoscopy with reduced number of state transition cycles. Opt Express 2011 0.82
144 High-resolution tracking of single-molecule diffusion in membranes by confocalized and spatially differentiated fluorescence photon stream recording. Chemphyschem 2014 0.82
145 Masked red-emitting carbopyronine dyes with photosensitive 2-diazo-1-indanone caging group. Photochem Photobiol Sci 2012 0.82
146 Stimulated-emission-depletion microscopy with a multicolor stimulated-Raman-scattering light source. Opt Lett 2008 0.81
147 Superresolution microscopy in heart - cardiac nanoscopy. J Mol Cell Cardiol 2012 0.81
148 4Pi microscopy of quantum dot-labeled cellular structures. J Struct Biol 2006 0.81
149 4Pi microscopy with linear fluorescence excitation. Opt Lett 2007 0.81
150 Tissue multicolor STED nanoscopy of presynaptic proteins in the calyx of Held. PLoS One 2013 0.81
151 STED microscopy with a MHz pulsed stimulated-Raman-scattering source. Opt Express 2009 0.81
152 isoSTED nanoscopy with intrinsic beam alignment. Opt Express 2015 0.79
153 Superresolving dendritic spines. Biophys J 2013 0.79
154 4-Trifluoromethyl-substituted coumarins with large Stokes shifts: synthesis, bioconjugates, and their use in super-resolution fluorescence microscopy. Chemistry 2013 0.78
155 Carborhodol: a new hybrid fluorophore obtained by combination of fluorescein and carbopyronine dye cores. Bioconjug Chem 2013 0.76
156 The tissue inhibitor of metalloproteinases-1 improves migration and adhesion of hematopoietic stem and progenitor cells. Exp Hematol 2013 0.76
157 1,3-bicyclo[1.1.1]pentanediyl: the shortest rigid linear connector of phenylated photochromic units and a 1,5-dimethoxy-9,10-di(phenylethynyl)anthracene fluorophore. Chemistry 2007 0.76
158 Phase determination in interference-based superresolving microscopes through critical frequency analysis. Opt Lett 2002 0.75
159 Cell-permeant large Stokes shift dyes for transfection-free multicolor nanoscopy. J Am Chem Soc 2017 0.75
160 Superresolution optical magnetic imaging and spectroscopy using individual electronic spins in diamond. Opt Express 2017 0.75
161 Influence of monolayer state on spectroscopy and photoisomerization of an amphiphilic styryl-pyridinium dye on a solid substrate. Langmuir 2007 0.75
162 Automatic deconvolution of 4Pi-microscopy data with arbitrary phase. Opt Lett 2009 0.75
163 Absolute optical cross section of individual fluorescent molecules. Angew Chem Int Ed Engl 2004 0.75
164 Molecular organization of an amphiphilic styryl pyridinium dye in monolayers at the air/water interface in the presence of various anions. Langmuir 2006 0.75
165 Monitoring triplet state dynamics with fluorescence correlation spectroscopy: bias and correction. Microsc Res Tech 2014 0.75
166 4Pi microscopy of type A with 1-photon excitation in biological fluorescence imaging. Opt Express 2007 0.75