Published in Nature on April 13, 2006
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science (2008) 6.47
Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature (2008) 6.38
Microscopy and its focal switch. Nat Methods (2009) 6.37
Breaking the diffraction barrier: super-resolution imaging of cells. Cell (2010) 5.83
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Superresolution imaging of chemical synapses in the brain. Neuron (2010) 3.51
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Live-cell imaging of dendritic spines by STED microscopy. Proc Natl Acad Sci U S A (2008) 2.53
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Two pathways of synaptic vesicle retrieval revealed by single-vesicle imaging. Neuron (2009) 2.38
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Putting super-resolution fluorescence microscopy to work. Nat Methods (2009) 2.25
A resting pool of vesicles is responsible for spontaneous vesicle fusion at the synapse. Nat Neurosci (2009) 2.09
Supraresolution imaging in brain slices using stimulated-emission depletion two-photon laser scanning microscopy. Neuron (2009) 1.99
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Squaraine rotaxanes: superior substitutes for Cy-5 in molecular probes for near-infrared fluorescence cell imaging. Angew Chem Int Ed Engl (2007) 1.47
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Protein quantification at the single vesicle level reveals that a subset of synaptic vesicle proteins are trafficked with high precision. J Neurosci (2011) 1.44
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Size and dynamics of caveolae studied using nanoparticles in living endothelial cells. ACS Nano (2009) 1.33
Deconvolving single-molecule intensity distributions for quantitative microscopy measurements. Biophys J (2007) 1.32
Analysis of diffusion and binding in cells using the RICS approach. Microsc Res Tech (2009) 1.31
Endosomal sorting of readily releasable synaptic vesicles. Proc Natl Acad Sci U S A (2010) 1.31
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Eight years of single-molecule localization microscopy. Histochem Cell Biol (2014) 1.24
Temperature-dependent phase behavior and protein partitioning in giant plasma membrane vesicles. Biochim Biophys Acta (2010) 1.20
STED nanoscopy with time-gated detection: theoretical and experimental aspects. PLoS One (2013) 1.20
Nano-scale dynamic recognition imaging on vascular endothelial cells. Biophys J (2007) 1.19
Seeing the forest tree by tree: super-resolution light microscopy meets the neurosciences. Nat Neurosci (2013) 1.18
Flip-flop-induced relaxation of bending energy: implications for membrane remodeling. Biophys J (2009) 1.18
The reserve pool of synaptic vesicles acts as a buffer for proteins involved in synaptic vesicle recycling. Proc Natl Acad Sci U S A (2011) 1.17
Nanometer-scale mapping and single-molecule detection with color-coded nanoparticle probes. Proc Natl Acad Sci U S A (2008) 1.17
Synaptic vesicle pools and dynamics. Cold Spring Harb Perspect Biol (2012) 1.17
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. Proc Natl Acad Sci U S A (2013) 1.16
STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA. Nat Methods (2013) 1.15
Multi-protein assemblies underlie the mesoscale organization of the plasma membrane. Nat Commun (2014) 1.10
Synaptic vesicle recycling: steps and principles. EMBO J (2014) 1.08
Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy. Mitochondrion (2011) 1.08
Making the message clear: visualizing mRNA localization. Trends Cell Biol (2010) 1.08
A novel immunofluorescent computed tomography (ICT) method to localise and quantify multiple antigens in large tissue volumes at high resolution. PLoS One (2012) 1.07
Synaptic vesicle protein trafficking at the glutamate synapse. Neuroscience (2008) 1.06
Differential dynamics of Rab3A and Rab27A on secretory granules. J Cell Sci (2007) 1.06
Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2. J Cell Biol (2007) 1.06
Photoactivated localization microscopy (PALM) of adhesion complexes. Curr Protoc Cell Biol (2008) 1.06
Super-resolution laser scanning microscopy through spatiotemporal modulation. Nano Lett (2009) 1.05
Two-photon excitation STED microscopy in two colors in acute brain slices. Biophys J (2013) 1.04
Three-dimensional structured illumination microscopy and its application to chromosome structure. Chromosome Res (2008) 1.04
Finding the middle ground: how kinetochores power chromosome congression. Cell Mol Life Sci (2010) 1.04
In vivo labeling method using a genetic construct for nanoscale resolution microscopy. Biophys J (2009) 1.03
Subdiffraction-limit two-photon fluorescence microscopy for GFP-tagged cell imaging. Biophys J (2009) 1.03
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Revisiting synaptic vesicle pool localization in the Drosophila neuromuscular junction. J Physiol (2009) 1.02
Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function. Mol Biol Cell (2014) 1.01
Aptamers as potential tools for super-resolution microscopy. Nat Methods (2012) 1.01
Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy. BMC Neurosci (2011) 1.01
Molecular mechanism of cholesterol- and polyphosphoinositide-mediated syntaxin clustering. Biochemistry (2011) 1.00
A new probe for super-resolution imaging of membranes elucidates trafficking pathways. J Cell Biol (2014) 0.99
SNARE function is not involved in early endosome docking. Mol Biol Cell (2008) 0.99
Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells. Mol Biol Cell (2011) 0.98
Novel application of fluorescence lifetime and fluorescence microscopy enables quantitative access to subcellular dynamics in plant cells. PLoS One (2009) 0.98
Seeing circuits assemble. Neuron (2008) 0.98
Rapid fusion of synaptic vesicles with reconstituted target SNARE membranes. Biophys J (2013) 0.96
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Filming biomolecular processes by high-speed atomic force microscopy. Chem Rev (2014) 0.95
Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity. J Neurosci (2012) 0.95
Two-colour live-cell nanoscale imaging of intracellular targets. Nat Commun (2016) 0.94
Enzyme-directed assembly of nanoparticles in tumors monitored by in vivo whole animal imaging and ex vivo super-resolution fluorescence imaging. J Am Chem Soc (2013) 0.93
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Clathrin-mediated endocytosis at the synaptic terminal: bridging the gap between physiology and molecules. Traffic (2010) 0.92
Molecular Biomechanics: The Molecular Basis of How Forces Regulate Cellular Function. Mol Cell Biomech (2010) 0.91
Active zone density is conserved during synaptic growth but impaired in aged mice. J Comp Neurol (2012) 0.91
Sorting in early endosomes reveals connections to docking- and fusion-associated factors. Proc Natl Acad Sci U S A (2009) 0.91
Fluorescence microscopy below the diffraction limit. Semin Cell Dev Biol (2009) 0.91
Imaging the post-fusion release and capture of a vesicle membrane protein. Nat Commun (2012) 0.91
Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy. Wiley Interdiscip Rev Syst Biol Med (2010) 0.91
Multicolour Multilevel STED nanoscopy of Actin/Spectrin Organization at Synapses. Sci Rep (2016) 0.90
Advances in light-based imaging of three-dimensional cellular ultrastructure. Curr Opin Cell Biol (2011) 0.90
Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2. Proc Natl Acad Sci U S A (2013) 0.90
Spatiotemporal Regulation of Signaling in and out of Dendritic Spines: CaMKII and Ras. Open Neurosci J (2009) 0.89
Massive Ca-induced membrane fusion and phospholipid changes triggered by reverse Na/Ca exchange in BHK fibroblasts. J Gen Physiol (2008) 0.89
Continuous fluorescence microphotolysis and correlation spectroscopy using 4Pi microscopy. Biophys J (2007) 0.88
Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry. J Biol Chem (2012) 0.88
Correlated optical and isotopic nanoscopy. Nat Commun (2014) 0.88
STED nanoscopy: a glimpse into the future. Cell Tissue Res (2015) 0.88
High- and low-mobility stages in the synaptic vesicle cycle. Biophys J (2010) 0.88
Molecular anatomy of a trafficking organelle. Cell (2006) 11.47
Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins. Proc Natl Acad Sci U S A (2005) 6.65
Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature (2008) 6.38
Video-rate far-field optical nanoscopy dissects synaptic vesicle movement. Science (2008) 5.87
Bruchpilot promotes active zone assembly, Ca2+ channel clustering, and vesicle release. Science (2006) 5.39
Fluorescence nanoscopy by ground-state depletion and single-molecule return. Nat Methods (2008) 4.69
Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters. Biophys J (2007) 3.93
Anatomy and dynamics of a supramolecular membrane protein cluster. Science (2007) 3.75
Nanoscale resolution in the focal plane of an optical microscope. Phys Rev Lett (2005) 3.60
Spherical nanosized focal spot unravels the interior of cells. Nat Methods (2008) 3.43
Nanoscale resolution in GFP-based microscopy. Nat Methods (2006) 3.19
CASK Functions as a Mg2+-independent neurexin kinase. Cell (2008) 3.10
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Helical extension of the neuronal SNARE complex into the membrane. Nature (2009) 2.92
A broken alpha -helix in folded alpha -Synuclein. J Biol Chem (2003) 2.80
Comparison of optical coherence tomography and ultrasound biomicroscopy for detection of narrow anterior chamber angles. Arch Ophthalmol (2005) 2.80
Anterior chamber width measurement by high-speed optical coherence tomography. Ophthalmology (2005) 2.77
Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nat Struct Mol Biol (2007) 2.63
STED microscopy with continuous wave beams. Nat Methods (2007) 2.62
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP. Nature (2011) 2.56
Live-cell imaging of dendritic spines by STED microscopy. Proc Natl Acad Sci U S A (2008) 2.53
Two-color far-field fluorescence nanoscopy. Biophys J (2007) 2.44
SNARE assembly and disassembly exhibit a pronounced hysteresis. Nat Struct Biol (2002) 2.40
Membrane protein sequestering by ionic protein-lipid interactions. Nature (2011) 2.40
Stimulated emission depletion (STED) nanoscopy of a fluorescent protein-labeled organelle inside a living cell. Proc Natl Acad Sci U S A (2008) 2.36
Protein localization in electron micrographs using fluorescence nanoscopy. Nat Methods (2010) 2.33
1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants. Biochem J (2007) 2.33
Tuning of synapse number, structure and function in the cochlea. Nat Neurosci (2009) 2.29
Determinants of liposome fusion mediated by synaptic SNARE proteins. Proc Natl Acad Sci U S A (2004) 2.28
Two-color nanoscopy of three-dimensional volumes by 4Pi detection of stochastically switched fluorophores. Nat Methods (2011) 2.28
2,2'-thiodiethanol: a new water soluble mounting medium for high resolution optical microscopy. Microsc Res Tech (2007) 2.23
A complete genetic analysis of neuronal Rab3 function. J Neurosci (2004) 2.21
Structure and mechanism of the reversible photoswitch of a fluorescent protein. Proc Natl Acad Sci U S A (2005) 2.21
Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nat Struct Biol (2002) 2.21
Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast. Proc Natl Acad Sci U S A (2002) 2.19
Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes. PLoS Biol (2006) 2.17
One SNARE complex is sufficient for membrane fusion. Nat Struct Mol Biol (2010) 2.14
Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids. Proc Natl Acad Sci U S A (2010) 2.14
A rapidly maturing far-red derivative of DsRed-Express2 for whole-cell labeling. Biochemistry (2009) 2.12
Structural basis for reversible photoswitching in Dronpa. Proc Natl Acad Sci U S A (2007) 2.08
Major signal increase in fluorescence microscopy through dark-state relaxation. Nat Methods (2006) 2.08
Focal spots of size lambda/23 open up far-field fluorescence microscopy at 33 nm axial resolution. Phys Rev Lett (2002) 2.06
The SNARE motif is essential for the formation of syntaxin clusters in the plasma membrane. Biophys J (2006) 2.04
Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells. Proc Natl Acad Sci U S A (2002) 2.03
Fluorescence microscopy with super-resolved optical sections. Trends Cell Biol (2005) 2.00
Resolution scaling in STED microscopy. Opt Express (2008) 1.89
Sharper low-power STED nanoscopy by time gating. Nat Methods (2011) 1.87
Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J Neurosci (2013) 1.82
Two-photon excitation STED microscopy. Opt Express (2009) 1.81
Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy. Nat Biotechnol (2008) 1.80
Nanoscopy in a living mouse brain. Science (2012) 1.80
Multicolor fluorescence nanoscopy in fixed and living cells by exciting conventional fluorophores with a single wavelength. Biophys J (2010) 1.74
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat Biotechnol (2011) 1.74
Correction of geometric and refractive image distortions in optical coherence tomography applying Fermat's principle. Opt Express (2002) 1.72
Membrane fusion intermediates via directional and full assembly of the SNARE complex. Science (2012) 1.71
Synaptic vesicle pools at the frog neuromuscular junction. Neuron (2003) 1.71
Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells. J Neurosci (2005) 1.71
STED nanoscopy of actin dynamics in synapses deep inside living brain slices. Biophys J (2011) 1.67
Generation of monomeric reversibly switchable red fluorescent proteins for far-field fluorescence nanoscopy. Biophys J (2008) 1.67
SNAREs prefer liquid-disordered over "raft" (liquid-ordered) domains when reconstituted into giant unilamellar vesicles. J Biol Chem (2004) 1.65
Molecular orientation affects localization accuracy in superresolution far-field fluorescence microscopy. Nano Lett (2010) 1.64
Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosis. J Biol Chem (2001) 1.63
rsEGFP2 enables fast RESOLFT nanoscopy of living cells. Elife (2012) 1.61
Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals. Proc Natl Acad Sci U S A (2007) 1.59
Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons. J Neurosci (2008) 1.59
Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity. Proc Natl Acad Sci U S A (2006) 1.59
RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release. Science (2011) 1.59
Wide-field subdiffraction RESOLFT microscopy using fluorescent protein photoswitching. Microsc Res Tech (2007) 1.58
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STED microscopy with a supercontinuum laser source. Opt Express (2008) 1.55
Breaking the diffraction barrier in fluorescence microscopy by optical shelving. Phys Rev Lett (2007) 1.53
Stimulated emission depletion nanoscopy of living cells using SNAP-tag fusion proteins. Biophys J (2010) 1.52
Criteria for the diagnosis of dysplasia by endoscopic optical coherence tomography. Gastrointest Endosc (2003) 1.52
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4Pi-microscopy of the Golgi apparatus in live mammalian cells. J Struct Biol (2004) 1.50
Maturation-dependent HIV-1 surface protein redistribution revealed by fluorescence nanoscopy. Science (2012) 1.50
Photostability of a fluorescent marker under pulsed excited-state depletion through stimulated emission. Appl Opt (2003) 1.49
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Nanoscopy with more than 100,000 'doughnuts'. Nat Methods (2013) 1.48
Stimulated emission depletion live-cell super-resolution imaging shows proliferative remodeling of T-tubule membrane structures after myocardial infarction. Circ Res (2012) 1.47
Coaligned dual-channel STED nanoscopy and molecular diffusion analysis at 20 nm resolution. Biophys J (2013) 1.46
Multicolor far-field fluorescence nanoscopy through isolated detection of distinct molecular species. Nano Lett (2008) 1.46
Block copolymer nanostructures mapped by far-field optics. Nano Lett (2009) 1.45
SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREs. J Cell Biol (2002) 1.45
Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane. Mol Syst Biol (2011) 1.44