Published in Am J Physiol Endocrinol Metab on November 19, 2013
Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization. Mol Ther (2015) 0.97
Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation. Am J Physiol Endocrinol Metab (2014) 0.83
Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms. Bone (2015) 0.81
Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength. Am J Physiol Endocrinol Metab (2014) 0.78
Optimizing IGF-I for skeletal muscle therapeutics. Growth Horm IGF Res (2014) 0.77
IGF expression in HPV-related and HPV-unrelated human cancer cells. Oncol Rep (2014) 0.77
Potency of Full- Length MGF to Induce Maximal Activation of the IGF-I R Is Similar to Recombinant Human IGF-I at High Equimolar Concentrations. PLoS One (2016) 0.76
Oncogenic Role of the Ec Peptide of the IGF-1Ec Isoform in Prostate Cancer. Mol Med (2015) 0.76
Editorial: the fall of mechanogrowth factor? Mol Endocrinol (2014) 0.75
Mechano growth factor-E regulates apoptosis and inflammatory responses in fibroblast-like synoviocytes of knee osteoarthritis. Int Orthop (2015) 0.75
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell (2004) 7.60
IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. Cell (2004) 6.25
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc (2011) 5.96
NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature (2003) 5.09
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev (2003) 3.74
Cancer cachexia: mediators, signaling, and metabolic pathways. Cell Metab (2012) 3.29
Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size. Am J Physiol Cell Physiol (2009) 3.18
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity. Nat Med (2005) 3.18
During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. J Cell Biol (2009) 3.03
The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle. Cell Metab (2007) 2.84
Effect of 10 days of bed rest on skeletal muscle in healthy older adults. JAMA (2007) 2.60
Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy. Mol Cell Biol (2004) 2.58
Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr (2002) 2.47
Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor. Bioorg Med Chem Lett (2003) 2.39
Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc (2011) 2.34
Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway. J Biol Chem (2004) 2.32
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. J Biol Chem (2003) 2.28
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. J Clin Invest (2007) 2.25
Effects of an ad libitum low-fat, high-carbohydrate diet on body weight, body composition, and fat distribution in older men and women: a randomized controlled trial. Arch Intern Med (2004) 2.08
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circ Res (2007) 2.05
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules. Comb Chem High Throughput Screen (2005) 1.99
Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proc Natl Acad Sci U S A (2008) 1.97
Anthropometric assessment of 10-y changes in body composition in the elderly. Am J Clin Nutr (2004) 1.92
ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23. Nat Immunol (2006) 1.83
Inhibition of Rho-kinase protects the heart against ischemia/reperfusion injury. Cardiovasc Res (2004) 1.80
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases. Nat Med (2012) 1.79
Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB. Circ Res (2011) 1.79
Predictors of weight loss in Parkinson's disease. Mov Disord (2006) 1.76
Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. J Biol Chem (2008) 1.75
Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3. J Clin Invest (2007) 1.70
The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice. J Cell Biol (2010) 1.61
Electrical impedance as a novel biomarker of myotube atrophy and hypertrophy. J Biomol Screen (2011) 1.59
Muscle wasting in cancer cachexia: clinical implications, diagnosis, and emerging treatment strategies. Annu Rev Med (2011) 1.57
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proc Natl Acad Sci U S A (2011) 1.56
Nutritional recommendations for the management of sarcopenia. J Am Med Dir Assoc (2010) 1.51
Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist. Arterioscler Thromb Vasc Biol (2006) 1.50
Permanent, non-leaching antibacterial surface--2: how high density cationic surfaces kill bacterial cells. Biomaterials (2007) 1.48
Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I. J Biol Chem (2008) 1.46
Signaling pathways controlling skeletal muscle mass. Crit Rev Biochem Mol Biol (2013) 1.43
Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis. Cancer Res (2006) 1.40
Functional impact of 10 days of bed rest in healthy older adults. J Gerontol A Biol Sci Med Sci (2008) 1.39
Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia. J Cachexia Sarcopenia Muscle (2012) 1.37
PPARbeta/delta ligands as modulators of the inflammatory response. Curr Opin Investig Drugs (2008) 1.36
Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis. Diabetes (2007) 1.34
Cloning, expression, and initial characterization of a novel cytokine-like gene family. Genomics (2002) 1.34
Muscle ring finger 1 mediates cardiac atrophy in vivo. Am J Physiol Heart Circ Physiol (2009) 1.33
beta4 integrin and epidermal growth factor coordinately regulate electric field-mediated directional migration via Rac1. Mol Biol Cell (2006) 1.32
Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR). J Biol Chem (2003) 1.32
Synthesis of uniform protein-polymer conjugates. Biomacromolecules (2005) 1.30
Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia. Mol Cell Biol (2012) 1.28
Aging alters macrophage properties in human skeletal muscle both at rest and in response to acute resistance exercise. Exp Gerontol (2006) 1.26
Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes. Cell Signal (2007) 1.26
Higher dietary variety is associated with better nutritional status in frail elderly people. J Am Diet Assoc (2002) 1.24
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines. Carcinogenesis (2007) 1.23
An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy. Mol Cell Biol (2013) 1.23
Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist. Mol Endocrinol (2007) 1.22
Molecular mechanisms and treatment options for muscle wasting diseases. Annu Rev Pharmacol Toxicol (2011) 1.21
Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol (2003) 1.21
MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle. Sci Signal (2012) 1.20
Energetics of walking in elderly people: factors related to gait speed. J Gerontol A Biol Sci Med Sci (2010) 1.20
Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity. Diabetes (2002) 1.19
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms. Carcinogenesis (2007) 1.18
Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem (2007) 1.18
Strong exchange and magnetic blocking in N₂³⁻-radical-bridged lanthanide complexes. Nat Chem (2011) 1.18
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities. J Pharmacol Exp Ther (2006) 1.17
The tumor necrosis factor-alpha converting enzyme (TACE): a unique metalloproteinase with highly defined substrate selectivity. Biochemistry (2002) 1.17
Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism. Mol Cell Biol (2012) 1.14
Discovery of 3-aryl-4-isoxazolecarboxamides as TGR5 receptor agonists. J Med Chem (2009) 1.13
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS Lett (2002) 1.13
The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling. Dev Cell (2011) 1.13
Myopenia-a new universal term for muscle wasting. J Cachexia Sarcopenia Muscle (2011) 1.12
The next generation of PPAR drugs: do we have the tools to find them? Biochim Biophys Acta (2007) 1.12
Rhabdomyosarcoma: current challenges and their implications for developing therapies. Cold Spring Harb Perspect Med (2014) 1.10
Permanent, nonleaching antibacterial surfaces. 1. Synthesis by atom transfer radical polymerization. Biomacromolecules (2004) 1.10
An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis. Dev Cell (2012) 1.10
Strength training, walking, and social activity improve sleep in nursing home and assisted living residents: randomized controlled trial. J Am Geriatr Soc (2011) 1.09
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines. Toxicology (2007) 1.09
Catalytic properties of ADAM19. J Biol Chem (2003) 1.09
Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype. Am J Physiol Heart Circ Physiol (2013) 1.09
Efficacy and feasibility of a novel tri-modal robust exercise prescription in a retirement community: a randomized, controlled trial. J Am Geriatr Soc (2007) 1.09
Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature. Cell Res (2011) 1.08
Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments. J Biol Chem (2010) 1.08
The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity. J Clin Endocrinol Metab (2009) 1.08
Matrix metalloproteinase-1 treatment of muscle fibrosis. Acta Biomater (2008) 1.07
TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A. Skelet Muscle (2012) 1.07
Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19. J Cell Sci (2007) 1.06
Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells. Cancer Lett (2002) 1.05
Calcium alginate microencapsulation of ovarian follicles impacts FSH delivery and follicle morphology. Reprod Biol Endocrinol (2005) 1.05
Chronic inhibition of hypoxia-inducible factor prolyl 4-hydroxylase improves ventricular performance, remodeling, and vascularity after myocardial infarction in the rat. J Cardiovasc Pharmacol (2010) 1.04
Matrix metalloproteinase-1 therapy improves muscle healing. J Appl Physiol (1985) (2007) 1.04
Expression profiling of peroxisome proliferator-activated receptor-delta (PPAR-delta) in mouse tissues using tissue microarray. Histochem Cell Biol (2007) 1.04
Exercise-induced changes in insulin action and glycogen metabolism in elderly adults. Med Sci Sports Exerc (2006) 1.03
Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-D3) dilution in rats. J Appl Physiol (1985) (2012) 1.02
The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3. FEBS Lett (2002) 1.02
ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. Mol Endocrinol (2009) 1.02
Decontamination of chemical and biological warfare agents with a single multi-functional material. Biomaterials (2010) 1.02
Increased TNFalpha and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis. Am J Physiol Endocrinol Metab (2007) 1.01