Steven E Brenner

Author PubWeight™ 318.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 WebLogo: a sequence logo generator. Genome Res 2004 59.58
2 The Bioperl toolkit: Perl modules for the life sciences. Genome Res 2002 58.63
3 SCOP database in 2002: refinements accommodate structural genomics. Nucleic Acids Res 2002 18.11
4 SCOP database in 2004: refinements integrate structure and sequence family data. Nucleic Acids Res 2004 15.21
5 The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol 2007 13.99
6 Data growth and its impact on the SCOP database: new developments. Nucleic Acids Res 2007 13.44
7 Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science 2010 12.39
8 The developmental transcriptome of Drosophila melanogaster. Nature 2010 11.85
9 Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. Proc Natl Acad Sci U S A 2002 10.28
10 The ASTRAL Compendium in 2004. Nucleic Acids Res 2004 10.03
11 Biases in Illumina transcriptome sequencing caused by random hexamer priming. Nucleic Acids Res 2010 9.08
12 Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements. Nature 2007 7.12
13 The impact of structural genomics: expectations and outcomes. Science 2006 5.30
14 A large-scale evaluation of computational protein function prediction. Nat Methods 2013 4.61
15 ASTRAL compendium enhancements. Nucleic Acids Res 2002 4.43
16 The RNA Ontology Consortium: an open invitation to the RNA community. RNA 2006 3.60
17 Protein molecular function prediction by Bayesian phylogenomics. PLoS Comput Biol 2005 3.14
18 The evolving roles of alternative splicing. Curr Opin Struct Biol 2004 2.99
19 SCOR: a Structural Classification of RNA database. Nucleic Acids Res 2002 2.79
20 Conservation of an RNA regulatory map between Drosophila and mammals. Genome Res 2010 2.43
21 An unappreciated role for RNA surveillance. Genome Biol 2004 2.28
22 Planning the human variome project: the Spain report. Hum Mutat 2009 2.22
23 SCOPe: Structural Classification of Proteins--extended, integrating SCOP and ASTRAL data and classification of new structures. Nucleic Acids Res 2013 2.22
24 Outcome of a workshop on applications of protein models in biomedical research. Structure 2009 2.05
25 Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila. Genes Dev 2005 2.03
26 SCOR: Structural Classification of RNA, version 2.0. Nucleic Acids Res 2004 2.02
27 RNA structural motifs: building blocks of a modular biomolecule. Q Rev Biophys 2006 1.88
28 Selection of primers for optimal taxonomic classification of environmental 16S rRNA gene sequences. ISME J 2012 1.86
29 Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes. Bioinformatics 2003 1.84
30 Statistical evaluation of pairwise protein sequence comparison with the Bayesian bootstrap. Bioinformatics 2005 1.77
31 The coupling of alternative splicing and nonsense-mediated mRNA decay. Adv Exp Med Biol 2007 1.77
32 Sulfotransferases and sulfatases in mycobacteria. Chem Biol 2002 1.74
33 Implications of structural genomics target selection strategies: Pfam5000, whole genome, and random approaches. Proteins 2005 1.71
34 Genome-wide analysis of alternative pre-mRNA splicing and RNA-binding specificities of the Drosophila hnRNP A/B family members. Mol Cell 2009 1.52
35 Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. PLoS Genet 2009 1.46
36 Three-dimensional motifs from the SCOR, structural classification of RNA database: extruded strands, base triples, tetraloops and U-turns. Nucleic Acids Res 2004 1.43
37 MeRNA: a database of metal ion binding sites in RNA structures. Nucleic Acids Res 2006 1.24
38 The COMBREX project: design, methodology, and initial results. PLoS Biol 2013 1.24
39 Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs. Mol Cell 2004 1.21
40 Automated multi-model reconstruction from single-particle electron microscopy data. J Struct Biol 2010 1.18
41 Structural genomics of minimal organisms and protein fold space. J Struct Funct Genomics 2005 1.16
42 A method for the alignment of heterogeneous macromolecules from electron microscopy. J Struct Biol 2008 1.16
43 Genome-scale phylogenetic function annotation of large and diverse protein families. Genome Res 2011 1.10
44 An alternative model of amino acid replacement. Bioinformatics 2004 1.10
45 A generalized affine gap model significantly improves protein sequence alignment accuracy. Proteins 2005 1.09
46 Newborn screening for SCID identifies patients with ataxia telangiectasia. J Clin Immunol 2012 1.05
47 Protein secondary structure: entropy, correlations and prediction. Bioinformatics 2004 1.04
48 Target selection and deselection at the Berkeley Structural Genomics Center. Proteins 2006 0.98
49 Structural studies of the Nudix hydrolase DR1025 from Deinococcus radiodurans and its ligand complexes. J Mol Biol 2004 0.93
50 Measurements of protein sequence-structure correlations. Proteins 2004 0.90
51 Pairwise alignment incorporating dipeptide covariation. Bioinformatics 2005 0.89
52 Survey of large protein complexes in D. vulgaris reveals great structural diversity. Proc Natl Acad Sci U S A 2009 0.86
53 Association of gut microbiota with post-operative clinical course in Crohn's disease. BMC Gastroenterol 2013 0.83
54 Nijmegen breakage syndrome detected by newborn screening for T cell receptor excision circles (TRECs). J Clin Immunol 2015 0.82
55 Personalized medicine: from genotypes, molecular phenotypes and the quantified self, towards improved medicine. Pac Symp Biocomput 2015 0.82
56 Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation. J Clin Immunol 2015 0.82
57 Phylogenetic molecular function annotation. J Phys Conf Ser 2009 0.81
58 High-throughput isolation and characterization of untagged membrane protein complexes: outer membrane complexes of Desulfovibrio vulgaris. J Proteome Res 2012 0.80
59 An SF1 affinity model to identify branch point sequences in human introns. Nucleic Acids Res 2010 0.79
60 Structural genomics and structural biology: compare and contrast. Genome Biol 2004 0.79
61 Alignment-free local structural search by writhe decomposition. Bioinformatics 2010 0.79
62 Molecular function prediction for a family exhibiting evolutionary tendencies toward substrate specificity swapping: recurrence of tyrosine aminotransferase activity in the Iα subfamily. Proteins 2013 0.78
63 PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY. Pac Symp Biocomput 2016 0.78
64 Identification and experimental validation of splicing regulatory elements in Drosophila melanogaster reveals functionally conserved splicing enhancers in metazoans. RNA 2011 0.78
65 A continuous fluorescence assay for the characterization of Nudix hydrolases. Anal Biochem 2013 0.77
66 ANDY: a general, fault-tolerant tool for database searching on computer clusters. Bioinformatics 2006 0.76
67 A novel plant enzyme with dual activity: an atypical Nudix hydrolase and a dipeptidyl peptidase III. Biol Chem 2017 0.75
68 Personalized medicine: from genotypes and molecular phenotypes towards therapy- session introduction. Pac Symp Biocomput 2014 0.75
69 PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY. Pac Symp Biocomput 2016 0.75
70 Optimal and fast rotational alignment of volumes with missing data in Fourier space. J Struct Biol 2013 0.75
71 PLoS Computational Biology: a new community journal. PLoS Comput Biol 2005 0.75
72 The future of genome-based medicine. Pac Symp Biocomput 2013 0.75
73 PRECISION MEDICINE: FROM DIPLOTYPES TO DISPARITIES TOWARDS IMPROVED HEALTH AND THERAPIES. Pac Symp Biocomput 2018 0.75
74 REGULATORY RNA. Pac Symp Biocomput 2016 0.75
75 Developing computational biology. PLoS Comput Biol 2007 0.75