Emerging links between homeostatic synaptic plasticity and neurological disease.

Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis. Ann Neurol (2014) 1.73

Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders. Neuron (2015) 1.24

Structural homeostasis in the nervous system: a balancing act for wiring plasticity and stability. Front Cell Neurosci (2015) 0.90

Where's the Noise? Key Features of Spontaneous Activity and Neural Variability Arise through Learning in a Deterministic Network. PLoS Comput Biol (2015) 0.81

Altered behavioral performance and live imaging of circuit-specific neural deficiencies in a zebrafish model for psychomotor retardation. PLoS Genet (2014) 0.80

Modulation of network activity and induction of homeostatic synaptic plasticity by enzymatic removal of heparan sulfates. Philos Trans R Soc Lond B Biol Sci (2014) 0.80

Vagal nerve stimulation blocks interleukin 6-dependent synaptic hyperexcitability induced by lipopolysaccharide-induced acute stress in the rodent prefrontal cortex. Brain Behav Immun (2014) 0.78

Vulnerability of synapses in the frontal cortex of mice developmentally exposed to an insecticide: Potential contribution to neuropsychiatric disease. Neurotransmitter (Houst) (2015) 0.77

Function Over Form: Modeling Groups of Inherited Neurological Conditions in Zebrafish. Front Mol Neurosci (2016) 0.76

Regulation of synaptic development and function by the Drosophila PDZ protein Dyschronic. Development (2014) 0.76

An Intrinsic Transcriptional Program Underlying Synaptic Scaling during Activity Suppression. Cell Rep (2017) 0.76

Differential targeting of dynamin-1 and dynamin-3 to nerve terminals during chronic suppression of neuronal activity. Mol Cell Neurosci (2015) 0.75

C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction. PLoS Genet (2016) 0.75

Inhibition of coactivator-associated arginine methyltransferase 1 modulates dendritic arborization and spine maturation of cultured hippocampal neurons. J Biol Chem (2017) 0.75

Subcellular structural plasticity caused by the absence of the fast Ca(2+) buffer calbindin D-28k in recurrent collaterals of cerebellar Purkinje neurons. Front Cell Neurosci (2014) 0.75

A New Fiji-Based Algorithm That Systematically Quantifies Nine Synaptic Parameters Provides Insights into Drosophila NMJ Morphometry. PLoS Comput Biol (2016) 0.75

Role of MicroRNA in Governing Synaptic Plasticity. Neural Plast (2016) 0.75

Neurophysiology and Regulation of the Balance Between Excitation and Inhibition in Neocortical Circuits. Biol Psychiatry (2016) 0.75

Reactive Neurogenesis and Down-Regulation of the Potassium-Chloride Cotransporter KCC2 in the Cochlear Nuclei after Cochlear Deafferentation. Front Pharmacol (2016) 0.75

Editorial: Homeostatic and retrograde signaling mechanisms modulating presynaptic function and plasticity. Front Cell Neurosci (2015) 0.75

A Presynaptic Glutamate Receptor Subunit Confers Robustness to Neurotransmission and Homeostatic Potentiation. Cell Rep (2017) 0.75

Homeostatic Presynaptic Plasticity Is Specifically Regulated by P/Q-type Ca(2+) Channels at Mammalian Hippocampal Synapses. Cell Rep (2017) 0.75

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science (2008) 20.68

Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet (2013) 13.17

Activity-dependent scaling of quantal amplitude in neocortical neurons. Nature (1998) 10.50

Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci (2004) 10.35

Migraine--current understanding and treatment. N Engl J Med (2002) 9.80

Neuroligins and neurexins link synaptic function to cognitive disease. Nature (2008) 9.23

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46

Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature (2011) 8.25

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02

The self-tuning neuron: synaptic scaling of excitatory synapses. Cell (2008) 7.06

Synaptic scaling mediated by glial TNF-alpha. Nature (2006) 6.76

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. Neuron (2008) 6.26

Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. Cell (1996) 5.99

Variability, compensation and homeostasis in neuron and network function. Nat Rev Neurosci (2006) 5.73

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann Neurol (2008) 5.55

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet (2007) 5.28

Induction, assembly, maturation and maintenance of a postsynaptic apparatus. Nat Rev Neurosci (2001) 5.10

Disruption of neurexin 1 associated with autism spectrum disorder. Am J Hum Genet (2008) 5.04

Translational control of long-lasting synaptic plasticity and memory. Neuron (2009) 4.77

Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis. Cell (2006) 4.35

Tuberous sclerosis. Lancet (2008) 4.24

Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature (2011) 4.13

Homeostatic control of neural activity: from phenomenology to molecular design. Annu Rev Neurosci (2006) 3.94

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo. Cell (1996) 3.81

Neurobiology of schizophrenia. Neuron (2006) 3.69

From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat Rev Neurosci (2005) 3.46

Mechanisms underlying the rapid induction and sustained expression of synaptic homeostasis. Neuron (2006) 3.37

Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat Med (2001) 3.26

Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature (2012) 3.13

Epidemiology of tuberous sclerosis. Ann N Y Acad Sci (1991) 2.96

Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. J Neurosci (1997) 2.93

Genetic analysis of glutamate receptors in Drosophila reveals a retrograde signal regulating presynaptic transmitter release. Neuron (1997) 2.91

Unraveling mechanisms of homeostatic synaptic plasticity. Neuron (2010) 2.85

Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients. Mol Psychiatry (2005) 2.78

Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function. Cold Spring Harb Perspect Biol (2012) 2.68

Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharmacology (1993) 2.57

Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity. Neuron (2008) 2.32

Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells. J Neurosci (2004) 2.20

The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci (2012) 2.16

The fragile X premutation: into the phenotypic fold. Curr Opin Genet Dev (2002) 2.15

Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis. Brain (2003) 2.11

Familial deletion within NLGN4 associated with autism and Tourette syndrome. Eur J Hum Genet (2008) 1.97

Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Hum Mol Genet (2004) 1.95

Fragile X protein FMRP is required for homeostatic plasticity and regulation of synaptic strength by retinoic acid. J Neurosci (2010) 1.92

The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis. Science (2009) 1.87

Homeostatic synaptic plasticity through changes in presynaptic calcium influx. J Neurosci (2011) 1.85

A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels. Neuron (2009) 1.79

Synaptic mechanisms underlying rapid antidepressant action of ketamine. Am J Psychiatry (2012) 1.69

A critical and cell-autonomous role for MeCP2 in synaptic scaling up. J Neurosci (2012) 1.69

The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits. J Neurosci (2009) 1.60

Altered Excitatory-Inhibitory Balance in the NMDA-Hypofunction Model of Schizophrenia. Front Mol Neurosci (2008) 1.58

Local presynaptic activity gates homeostatic changes in presynaptic function driven by dendritic BDNF synthesis. Neuron (2010) 1.57

Arc-dependent synapse-specific homeostatic plasticity. Proc Natl Acad Sci U S A (2010) 1.56

Presynaptic Ca2+ channels compete for channel type-preferring slots in altered neurotransmission arising from Ca2+ channelopathy. Neuron (2004) 1.56

Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons. Nat Neurosci (2010) 1.54

The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway. PLoS One (2012) 1.53

Synapse-specific control of synaptic efficacy at the terminals of a single neuron. Nature (1998) 1.51

Functional consequences of mutations in the human alpha1A calcium channel subunit linked to familial hemiplegic migraine. J Neurosci (1999) 1.48

Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. Nat Neurosci (2010) 1.48

Role of retinoid signalling in the adult brain. Prog Neurobiol (2005) 1.47

Familial hemiplegic migraine mutations change alpha1A Ca2+ channel kinetics. J Biol Chem (1998) 1.44

DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release. J Cell Biol (2008) 1.42

Three hypotheses for developmental defects that may underlie some forms of autism spectrum disorder. Curr Opin Neurol (2010) 1.41

A specific requirement of Arc/Arg3.1 for visual experience-induced homeostatic synaptic plasticity in mouse primary visual cortex. J Neurosci (2010) 1.41

Migraine: a complex genetic disorder. Lancet Neurol (2007) 1.39

Adaptation of quantal content to decreased postsynaptic sensitivity at single endplates in alpha-bungarotoxin-treated rats. J Physiol (1992) 1.38

Synaptic plasticity in sleep: learning, homeostasis and disease. Trends Neurosci (2011) 1.37

On the release of transmitter at normal, myasthenia gravis and myasthenic syndrome affected human end-plates. J Physiol (1980) 1.34

Autism spectrum disorder in fragile X syndrome: a longitudinal evaluation. Am J Med Genet A (2009) 1.33

Signals, synapses, and synthesis: how new proteins control plasticity. Front Neural Circuits (2009) 1.31

Mutation in Rab3 GTPase-activating protein (RAB3GAP) noncatalytic subunit in a kindred with Martsolf syndrome. Am J Hum Genet (2006) 1.30

Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility. Biol Psychiatry (2007) 1.23

Homeostatic synaptic plasticity: from single synapses to neural circuits. Curr Opin Neurobiol (2011) 1.22

Retinoic acid regulates RARalpha-mediated control of translation in dendritic RNA granules during homeostatic synaptic plasticity. Proc Natl Acad Sci U S A (2008) 1.20

Rab3-GAP controls the progression of synaptic homeostasis at a late stage of vesicle release. Neuron (2011) 1.18

The Rett syndrome protein MeCP2 regulates synaptic scaling. J Neurosci (2012) 1.16

Transsynaptic control of presynaptic Ca²⁺ influx achieves homeostatic potentiation of neurotransmitter release. Curr Biol (2012) 1.13

Impairment of TrkB-PSD-95 signaling in Angelman syndrome. PLoS Biol (2013) 1.13

Effects of familial hemiplegic migraine type 1 mutations on neuronal P/Q-type Ca2+ channel activity and inhibitory synaptic transmission. Proc Natl Acad Sci U S A (2005) 1.13

MeCP2 phosphorylation is required for modulating synaptic scaling through mGluR5. J Neurosci (2012) 1.12

Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference. EMBO Rep (2004) 1.11

Mammalian target of rapamycin (mTOR) inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy. Curr Neurol Neurosci Rep (2012) 1.09

mTOR Inhibitors in Tuberous Sclerosis Complex. Curr Neuropharmacol (2012) 1.09

Decrease in calcium concentration triggers neuronal retinoic acid synthesis during homeostatic synaptic plasticity. J Neurosci (2011) 1.08

Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions. J Comp Neurol (2012) 1.05

Genetic analysis of synaptic development and plasticity: homeostatic regulation of synaptic efficacy. Curr Opin Neurobiol (1998) 1.05

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse. Mol Biol Cell (2011) 1.04

Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene. Mol Neurobiol (2011) 1.04

Arc in the nucleus regulates PML-dependent GluA1 transcription and homeostatic plasticity. Nat Neurosci (2013) 1.04

A presynaptic ENaC channel drives homeostatic plasticity. Neuron (2013) 1.03

Schizophrenia: the "BLOC" may be in the endosomes. Sci Signal (2009) 1.00

Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade. ASN Neuro (2011) 0.97

Homeostatic plasticity at the Drosophila neuromuscular junction. Neuropharmacology (2013) 0.97

Clathrin-mediated endocytosis is required for compensatory regulation of GLR-1 glutamate receptors after activity blockade. Proc Natl Acad Sci U S A (2004) 0.96

The epidemiology of epilepsy and learning disability. Epilepsia (2001) 0.95

TOR is required for the retrograde regulation of synaptic homeostasis at the Drosophila neuromuscular junction. Neuron (2012) 0.94

Pre- and postsynaptic neuromuscular junction abnormalities in musk myasthenia. Muscle Nerve (2010) 0.94

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction. Neuroscience (2006) 0.94

Passive and active immunization models of MuSK-Ab positive myasthenia: electrophysiological evidence for pre and postsynaptic defects. Exp Neurol (2012) 0.93