Factors associated with major bleeding events: insights from the ROCKET AF trial (rivaroxaban once-daily oral direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation).

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Published in J Am Coll Cardiol on December 04, 2013

Authors

Shaun G Goodman1, Daniel M Wojdyla2, Jonathan P Piccini2, Harvey D White3, John F Paolini4, Christopher C Nessel5, Scott D Berkowitz4, Kenneth W Mahaffey2, Manesh R Patel2, Matthew W Sherwood2, Richard C Becker2, Jonathan L Halperin6, Werner Hacke7, Daniel E Singer8, Graeme J Hankey9, Gunter Breithardt10, Keith A A Fox11, Robert M Califf12, ROCKET AF Investigators

Author Affiliations

1: Canadian Heart Research Centre and Terrence Donnelly Heart Centre, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: goodmans@chrc.net.
2: Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
3: Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.
4: Bayer HealthCare Pharmaceuticals, Montville, New Jersey.
5: Janssen Research and Development, Raritan, New Jersey.
6: Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.
7: Ruprecht-Karls-University, Heidelberg, Germany.
8: Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
9: Royal Perth Hospital, Perth, Australia.
10: Hospital of the University of Münster, Münster, Germany.
11: University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom.
12: Duke Clinical Research Institute and Duke Translational Medicine Institute, Duke University Medical Center, Durham, North Carolina.

Associated clinical trials:

An Efficacy and Safety Study of Rivaroxaban With Warfarin for the Prevention of Stroke and Non-Central Nervous System Systemic Embolism in Patients With Non-Valvular Atrial Fibrillation | NCT00403767

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