Alternative calculations of individual patient time in therapeutic range while taking warfarin: results from the ROCKET AF trial.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 4392426)

Published in J Am Heart Assoc on March 03, 2015

Authors

Daniel E Singer1, Anne S Hellkamp2, Zhong Yuan3, Yuliya Lokhnygina2, Manesh R Patel2, Jonathan P Piccini2, Graeme J Hankey4, Günter Breithardt5, Jonathan L Halperin6, Richard C Becker7, Werner Hacke8, Christopher C Nessel3, Kenneth W Mahaffey9, Keith A A Fox10, Robert M Califf11, ROCKET AF Investigators

Author Affiliations

1: Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA (D.E.S.).
2: Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (A.S.H., Y.L., M.R.P., J.P.P.).
3: Janssen Pharmaceuticals, Raritan, NJ (Z.Y., C.C.N.).
4: School of Medicine and Pharmacology, University of Western Australia, Crawley, Australia (G.J.H.).
5: Division of Electrophysiology, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany (B.).
6: Mount Sinai Medical Center, The Cardiovascular Institute, New York, NY (J.L.H.).
7: Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH (R.C.B.).
8: Ruprecht-Karls-University, Heidelberg, Germany (W.H.).
9: Department of Medicine, Stanford University, Stanford, CA (K.W.M.).
10: University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, UK (K.A.F.).
11: Duke Translational Medicine Institute, Duke University Medical Center, Durham, NC (R.M.C.).

Associated clinical trials:

An Efficacy and Safety Study of Rivaroxaban With Warfarin for the Prevention of Stroke and Non-Central Nervous System Systemic Embolism in Patients With Non-Valvular Atrial Fibrillation | NCT00403767

Articles citing this

Availability of Clinical Trial Data From Industry-Sponsored Cardiovascular Trials. J Am Heart Assoc (2016) 0.75

Articles cited by this

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med (2011) 28.99

2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J (2012) 12.36

2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol (2014) 9.96

A method to determine the optimal intensity of oral anticoagulant therapy. Thromb Haemost (1993) 7.92

Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial. Lancet (2010) 6.31

Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 5.27

Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 4.82

Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (2001) 3.64

Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial. Lancet (1996) 3.03

Benefit of oral anticoagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and countries as measured by time in therapeutic range. Circulation (2008) 2.98

Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation: rationale and design of the ROCKET AF study. Am Heart J (2010) 2.46

National trends in oral anticoagulant use in the United States, 2007 to 2011. Circ Cardiovasc Qual Outcomes (2012) 2.27

Comparison of outcomes among patients randomized to warfarin therapy according to anticoagulant control: results from SPORTIF III and V. Arch Intern Med (2007) 2.20

Anticoagulation control in Sweden: reports of time in therapeutic range, major bleeding, and thrombo-embolic complications from the national quality registry AuriculA. Eur Heart J (2011) 1.67

Risk-adjusted percent time in therapeutic range as a quality indicator for outpatient oral anticoagulation: results of the Veterans Affairs Study to Improve Anticoagulation (VARIA). Circ Cardiovasc Qual Outcomes (2010) 1.50

Should patient characteristics influence target anticoagulation intensity for stroke prevention in nonvalvular atrial fibrillation?: the ATRIA study. Circ Cardiovasc Qual Outcomes (2009) 1.29

Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: data from the ROCKET AF clinical trial. J Am Heart Assoc (2013) 1.26

National assessment of warfarin anticoagulation therapy for stroke prevention in atrial fibrillation. Circulation (2014) 1.19

Warfarin. From bedside to bench. N Engl J Med (1984) 1.05

Analytical performance of the new coagulation monitoring system INRatio for the determination of INR compared with the coagulation monitor Coaguchek S and an established laboratory method. J Thromb Thrombolysis (2004) 0.82

The relationship between maintenance dosages of three vitamin K antagonists: acenocoumarol, warfarin and phenprocoumon. Thromb Res (2008) 0.80

A new era in stroke prevention for atrial fibrillation: comment on "current trial-associated outcomes with warfarin in prevention of stroke in patients with nonvalvular atrial fibrillation. Arch Intern Med (2012) 0.78

Articles by these authors

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med (2011) 28.99

Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF). Circulation (2014) 1.54

Ischaemic cardiac outcomes in patients with atrial fibrillation treated with vitamin K antagonism or factor Xa inhibition: results from the ROCKET AF trial. Eur Heart J (2013) 1.53

Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: data from the ROCKET AF clinical trial. J Am Heart Assoc (2013) 1.26

Factors associated with major bleeding events: insights from the ROCKET AF trial (rivaroxaban once-daily oral direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation). J Am Coll Cardiol (2013) 1.20

Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial. Eur Heart J (2014) 1.12

Relationship between time in therapeutic range and comparative treatment effect of rivaroxaban and warfarin: results from the ROCKET AF trial. J Am Heart Assoc (2014) 0.85

Reduction in overall occurrences of ischemic events with vorapaxar: results from TRACER. J Am Heart Assoc (2014) 0.77