Published in Bioanalysis on December 01, 2013
Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets. J Lipid Res (2014) 0.84
Stable isotopes and LC-MS for monitoring metabolic disturbances in Friedreich's ataxia platelets. Bioanalysis (2015) 0.82
Frataxin levels in peripheral tissue in Friedreich ataxia. Ann Clin Transl Neurol (2015) 0.80
LC-MS Analysis of Human Platelets as a Platform for Studying Mitochondrial Metabolism. J Vis Exp (2016) 0.78
Translational metabolomics in cancer research. Biomark Med (2015) 0.78
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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature (2011) 7.94
Mitochondria and cancer. Nat Rev Cancer (2012) 4.81
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metab (2012) 4.80
Rotenone, paraquat, and Parkinson's disease. Environ Health Perspect (2011) 3.87
The role of mitochondria in the pathogenesis of type 2 diabetes. Endocr Rev (2010) 2.59
Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells. J Biotechnol (2009) 2.08
Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomics. Nat Protoc (2011) 1.99
Coenzyme A biosynthesis: an antimicrobial drug target. FEMS Microbiol Rev (2008) 1.68
Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. Front Biosci (2007) 1.65
Quantitation of fatty acyl-coenzyme As in mammalian cells by liquid chromatography-electrospray ionization tandem mass spectrometry. J Lipid Res (2008) 1.57
Stable-isotope dilution LC–MS for quantitative biomarker analysis. Bioanalysis (2010) 1.56
Acyl-coenzyme A synthetases in metabolic control. Curr Opin Lipidol (2010) 1.54
Brain aging, Alzheimer's disease, and mitochondria. Biochim Biophys Acta (2011) 1.36
Understanding the molecular mechanisms of Friedreich's ataxia to develop therapeutic approaches. Hum Mol Genet (2010) 1.33
A rapid, noninvasive immunoassay for frataxin: utility in assessment of Friedreich ataxia. Mol Genet Metab (2010) 1.32
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. PLoS One (2012) 1.27
Friedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities. Antioxid Redox Signal (2010) 1.27
Mitochondrial dysfunction in autism spectrum disorders: cause or effect? Biochim Biophys Acta (2010) 1.18
Proteomics and metabolomics analysis of a trait anxiety mouse model reveals divergent mitochondrial pathways. Biol Psychiatry (2011) 1.14
Hereditary and acquired diseases of acyl-coenzyme A metabolism. Mol Genet Metab (2008) 1.09
Stable isotope labeling by essential nutrients in cell culture for preparation of labeled coenzyme A and its thioesters. Anal Chem (2011) 1.08
SILEC: a protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards. Nat Protoc (2011) 1.08
Validated comprehensive analytical method for quantification of coenzyme A activated compounds in biological tissues by online solid-phase extraction LC/MS/MS. Anal Chem (2008) 1.08
Surrogate tissue analysis: monitoring toxicant exposure and health status of inaccessible tissues through the analysis of accessible tissues and cells. Toxicol Appl Pharmacol (2004) 1.02
Mitochondria and heart disease. Adv Exp Med Biol (2012) 1.02
Rotenone-mediated changes in intracellular coenzyme A thioester levels: implications for mitochondrial dysfunction. Chem Res Toxicol (2011) 1.00
Biomarkers for mitochondrial respiratory chain disorders. J Inherit Metab Dis (2010) 0.97
Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer. J Proteome Res (2009) 0.96
Blood cells from Friedreich ataxia patients harbor frataxin deficiency without a loss of mitochondrial function. Mitochondrion (2010) 0.96
Metabolomics in the study of aging and caloric restriction. Methods Mol Biol (2007) 0.95
Measurement of tissue acyl-CoAs using flow-injection tandem mass spectrometry: acyl-CoA profiles in short-chain fatty acid oxidation defects. Mol Genet Metab (2012) 0.93
Genetics and mitochondrial abnormalities in autism spectrum disorders: a review. Curr Genomics (2011) 0.89
Targeting mitochondria for neuroprotection in Parkinson's disease. Antioxid Redox Signal (2012) 0.88
In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs. Chem Res Toxicol (2012) 0.83
Urine organic acid analysis for inherited metabolic disease using gas chromatography-mass spectrometry. Methods Mol Biol (2010) 0.81
Unanswered questions in Friedreich ataxia. J Child Neurol (2012) 0.80
Platelet glutamate uptake and release in migraine with and without aura. Cephalalgia (2007) 0.80
Assessing glutamatergic function and dysfunction in peripheral tissues. Curr Med Chem (2012) 0.76
Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol (2008) 21.53
Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol (2007) 16.81
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature (2011) 9.70
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol (2009) 9.25
Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. J Neurosci (2010) 6.44
A patient with encephalitis associated with NMDA receptor antibodies. Nat Clin Pract Neurol (2007) 4.63
AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Ann Neurol (2009) 4.49
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood (2010) 3.35
N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease. Neuroscientist (2005) 3.11
DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med (2005) 3.06
Mutations in the gene PRRT2 cause paroxysmal kinesigenic dyskinesia with infantile convulsions. Cell Rep (2011) 2.17
ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet (2008) 2.04
The E46K mutation in alpha-synuclein increases amyloid fibril formation. J Biol Chem (2005) 1.98
Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems. J Biol Chem (2007) 1.84
FXN methylation predicts expression and clinical outcome in Friedreich ataxia. Ann Neurol (2012) 1.83
Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain. J Neurosci (2012) 1.82
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells. Immunity (2016) 1.74
Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells. J Biol Chem (2002) 1.70
Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells. Proc Natl Acad Sci U S A (2008) 1.60
Negative regulation of activated alpha-2 integrins during thrombopoiesis. Blood (2009) 1.59
Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. J Biol Chem (2004) 1.58
Stable-isotope dilution LC–MS for quantitative biomarker analysis. Bioanalysis (2010) 1.56
Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry. Rapid Commun Mass Spectrom (2003) 1.50
Relative quantification of serum proteins from pancreatic ductal adenocarcinoma patients by stable isotope dilution liquid chromatography-mass spectrometry. J Proteome Res (2012) 1.47
Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome. Am J Psychiatry (2004) 1.43
Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates. J Neurosci (2006) 1.43
Clinical measures of dysarthria in Friedreich Ataxia. Mov Disord (2010) 1.43
Human immunodeficiency virus (HIV)-induced neurotoxicity: roles for the NMDA receptor subtypes. J Neurosci (2006) 1.39
High-throughput immunoassay for the biochemical diagnosis of Friedreich ataxia in dried blood spots and whole blood. Clin Chem (2013) 1.39
Polymicrogyria and deletion 22q11.2 syndrome: window to the etiology of a common cortical malformation. Am J Med Genet A (2006) 1.38
Calpain and synaptic function. Mol Neurobiol (2006) 1.37
EBP, a program for protein identification using multiple tandem mass spectrometry datasets. Mol Cell Proteomics (2006) 1.36
Hemizygous mutations in SNAP29 unmask autosomal recessive conditions and contribute to atypical findings in patients with 22q11.2DS. J Med Genet (2012) 1.33
Determination of cellular redox status by stable isotope dilution liquid chromatography/mass spectrometry analysis of glutathione and glutathione disulfide. Rapid Commun Mass Spectrom (2008) 1.33
Mortality in Friedreich ataxia. J Neurol Sci (2011) 1.33
A rapid, noninvasive immunoassay for frataxin: utility in assessment of Friedreich ataxia. Mol Genet Metab (2010) 1.32
Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress. Chem Res Toxicol (2009) 1.31
Effect of immunoaffinity depletion of human serum during proteomic investigations. J Proteome Res (2005) 1.30
Measuring the rate of progression in Friedreich ataxia: implications for clinical trial design. Mov Disord (2010) 1.29
TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase. Development (2009) 1.28
Selective activation induced cleavage of the NR2B subunit by calpain. J Neurosci (2003) 1.26
Characterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometry. J Proteome Res (2005) 1.24
Quantitative analysis of amyloid beta peptides in cerebrospinal fluid of Alzheimer's disease patients by immunoaffinity purification and stable isotope dilution liquid chromatography/negative electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom (2006) 1.22
Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro. J Neurochem (2003) 1.22
Senataxin, the yeast Sen1p orthologue: characterization of a unique protein in which recessive mutations cause ataxia and dominant mutations cause motor neuron disease. Neurobiol Dis (2006) 1.21
Structure-function analysis reveals discrete beta3 integrin inside-out and outside-in signaling pathways in platelets. Blood (2006) 1.19
Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery. J Proteome Res (2009) 1.18
Cyclooxygenase-2-mediated DNA damage. J Biol Chem (2005) 1.18
N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase. J Biol Chem (2005) 1.16
Analysis of the human pancreatic stellate cell secreted proteome. Pancreas (2011) 1.16
Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein. Biochemistry (2005) 1.16
Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism. Blood (2010) 1.14
MicroRNA expression in maturing murine megakaryocytes. Blood (2010) 1.12
Endogenous lipid hydroperoxide-mediated DNA-adduct formation in min mice. J Biol Chem (2006) 1.10
Metabolism of benzo[a]pyrene in human bronchoalveolar H358 cells using liquid chromatography-mass spectrometry. Chem Res Toxicol (2007) 1.10
15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation. Mol Pharmacol (2009) 1.10
A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4. J Biol Chem (2003) 1.09
Analysis of the zebrafish proteome during embryonic development. Mol Cell Proteomics (2008) 1.09
Analysis of phosphorylation sites on focal adhesion kinase using nanospray liquid chromatography/multiple reaction monitoring mass spectrometry. Rapid Commun Mass Spectrom (2006) 1.08
Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction. Chem Res Toxicol (2006) 1.08
Stable isotope labeling by essential nutrients in cell culture for preparation of labeled coenzyme A and its thioesters. Anal Chem (2011) 1.08
SILEC: a protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards. Nat Protoc (2011) 1.08
Characterization of 2'-deoxycytidine adducts derived from 4-oxo-2-nonenal, a novel lipid peroxidation product. Chem Res Toxicol (2003) 1.07
Absolute quantification of phosphorylation on the kinase activation loop of cellular focal adhesion kinase by stable isotope dilution liquid chromatography/mass spectrometry. Anal Chem (2009) 1.07
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. J Steroid Biochem Mol Biol (2009) 1.07
Interactions of postsynaptic density-95 and the NMDA receptor 2 subunit control calpain-mediated cleavage of the NMDA receptor. J Neurosci (2004) 1.06
Proteolysis of the N-methyl-d-aspartate receptor by calpain in situ. J Pharmacol Exp Ther (2002) 1.06
Liquid chromatography-mass spectrometry (LC-MS) of steroid hormone metabolites and its applications. J Steroid Biochem Mol Biol (2010) 1.05
4,5-Epoxy-2(E)-decenal-induced formation of 1,N(6)-etheno-2'-deoxyadenosine and 1,N(2)-etheno-2'-deoxyguanosine adducts. Chem Res Toxicol (2002) 1.05
Detoxication of benzo[a]pyrene-7,8-dione by sulfotransferases (SULTs) in human lung cells. J Biol Chem (2012) 1.05
Deciphering the human platelet sheddome. Blood (2010) 1.04
Secondhand smoke inhibits both Cl- and K+ conductances in normal human bronchial epithelial cells. Respir Res (2009) 1.04
Advancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments. Mol Genet Metab (2007) 1.04
Untargeted metabolomics from biological sources using ultraperformance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS). J Vis Exp (2013) 1.03
The post-synaptic density of human postmortem brain tissues: an experimental study paradigm for neuropsychiatric illnesses. PLoS One (2009) 1.03
Targeted chiral lipidomics analysis by liquid chromatography electron capture atmospheric pressure chemical ionization mass spectrometry (LC-ECAPCI/MS). Methods Enzymol (2007) 1.03
The effect of menthol on cigarette smoking behaviors, biomarkers and subjective responses. Cancer Epidemiol Biomarkers Prev (2013) 1.03
4-Hydroperoxy-2-nonenal-induced formation of 1,N2-etheno-2'-deoxyguanosine adducts. Chem Res Toxicol (2005) 1.03
Targeted quantitative analysis of fatty acids in atherosclerotic plaques by high sensitivity liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 1.02
Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month phase III study (IONIA). Am Heart J (2011) 1.01
Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles. Free Radic Biol Med (2005) 1.01
Rotenone-mediated changes in intracellular coenzyme A thioester levels: implications for mitochondrial dysfunction. Chem Res Toxicol (2011) 1.00
Targeted quantitative analysis of eicosanoid lipids in biological samples using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 1.00
CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). J Biol Chem (2011) 1.00
Increased prevalence of unprovoked seizures in patients with a 22q11.2 deletion. Am J Med Genet A (2004) 1.00
Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism. J Biol Chem (2009) 0.99
Aldo-keto reductase- and cytochrome P450-dependent formation of benzo[a]pyrene-derived DNA adducts in human bronchoalveolar cells. Chem Res Toxicol (2007) 0.99
Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells. Chem Res Toxicol (2007) 0.99
Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard. J Proteome Res (2005) 0.99
Proteomics-based strategy to identify biomarkers and pharmacological targets in leukemias with t(4;11) translocations. J Proteome Res (2006) 0.98
Genetic and clinical heterogeneity in eIF2B-related disorder. J Child Neurol (2008) 0.98
Mild folate deficiency induces a proatherosclerotic phenotype in endothelial cells. Atherosclerosis (2006) 0.98
Identification and quantification of preterm birth biomarkers in human cervicovaginal fluid by liquid chromatography/tandem mass spectrometry. J Proteome Res (2009) 0.98
Detoxication of structurally diverse polycyclic aromatic hydrocarbon (PAH) o-quinones by human recombinant catechol-O-methyltransferase (COMT) via O-methylation of PAH catechols. J Biol Chem (2011) 0.98
Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury. J Neurochem (2007) 0.97
Synthesis of phenol and quinone metabolites of benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer. J Org Chem (2009) 0.97
Nicotine exposure and metabolizer phenotypes from analysis of urinary nicotine and its 15 metabolites by LC-MS. Bioanalysis (2011) 0.97
Effects of 21 days of varenicline versus placebo on smoking behaviors and urges among non-treatment seeking smokers. J Psychopharmacol (2012) 0.97