Measuring quality metrics to identify and monitor antimicrobial stewardship program quality improvement efforts.

Use of a structured panel process to define quality metrics for antimicrobial stewardship programs. Infect Control Hosp Epidemiol (2012) 1.80

MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med (2007) 5.48

Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation. Eur J Immunol (2007) 4.19

A four-tiered transcriptional regulatory circuit controls flagellar biogenesis in Pseudomonas aeruginosa. Mol Microbiol (2003) 3.05

Pseudomonas aeruginosa regulates flagellin expression as part of a global response to airway fluid from cystic fibrosis patients. Proc Natl Acad Sci U S A (2004) 1.58

Sepsis induces early alterations in innate immunity that impact mortality to secondary infection. J Immunol (2010) 1.54

Role of motility and flagellin glycosylation in the pathogenesis of Pseudomonas aeruginosa burn wound infections. Infect Immun (2005) 1.43

Poly-L-Lysine compacts DNA, kills bacteria, and improves protease inhibition in cystic fibrosis sputum. Am J Respir Crit Care Med (2013) 1.42

Roles of specific amino acids in the N terminus of Pseudomonas aeruginosa flagellin and of flagellin glycosylation in the innate immune response. Infect Immun (2005) 1.38

fleQ, the gene encoding the major flagellar regulator of Pseudomonas aeruginosa, is sigma70 dependent and is downregulated by Vfr, a homolog of Escherichia coli cyclic AMP receptor protein. J Bacteriol (2002) 1.36

FleQ, the major flagellar gene regulator in Pseudomonas aeruginosa, binds to enhancer sites located either upstream or atypically downstream of the RpoN binding site. J Bacteriol (2002) 1.36

Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells. PLoS One (2009) 1.35

The role of flagellin versus motility in acute lung disease caused by Pseudomonas aeruginosa. J Infect Dis (2007) 1.26

Sequence polymorphism in the glycosylation island and flagellins of Pseudomonas aeruginosa. J Bacteriol (2004) 1.23

Real-world experience with echinocandin MICs against Candida species in a multicenter study of hospitals that routinely perform susceptibility testing of bloodstream isolates. Antimicrob Agents Chemother (2014) 1.21

Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling. J Immunol (2011) 1.21

Large retrospective evaluation of the effectiveness and safety of ceftaroline fosamil therapy. Antimicrob Agents Chemother (2014) 1.17

Flagellin enhances NK cell proliferation and activation directly and through dendritic cell-NK cell interactions. J Leukoc Biol (2005) 1.12

Glycosylation of b-Type flagellin of Pseudomonas aeruginosa: structural and genetic basis. J Bacteriol (2006) 1.12

Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing. Proc Natl Acad Sci U S A (2012) 1.05

Neutrophil elastase, an innate immunity effector molecule, represses flagellin transcription in Pseudomonas aeruginosa. Infect Immun (2006) 0.97

Genetic mechanisms involved in the repression of flagellar assembly by Pseudomonas aeruginosa in human mucus. Mol Microbiol (2007) 0.95

Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia. J Immunol (2009) 0.94

Type II secretion system of Pseudomonas aeruginosa: in vivo evidence of a significant role in death due to lung infection. J Infect Dis (2011) 0.94

Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa. FEMS Immunol Med Microbiol (2008) 0.93

Thrombocytopenia secondary to linezolid administration: what is the risk? Clin Infect Dis (2002) 0.93

Fluconazole versus an echinocandin for Candida glabrata fungaemia: a retrospective cohort study. J Antimicrob Chemother (2012) 0.92

Pseudomonas aeruginosa LecB is involved in pilus biogenesis and protease IV activity but not in adhesion to respiratory mucins. Infect Immun (2006) 0.90

A crucial role of Flagellin in the induction of airway mucus production by Pseudomonas aeruginosa. PLoS One (2012) 0.85

Time to positivity of blood cultures supports antibiotic de-escalation at 48 hours. Ann Pharmacother (2013) 0.84

Flagellin concentrations in expectorations from cystic fibrosis patients. BMC Pulm Med (2014) 0.78

Impact of the CYP2C19 genotype on voriconazole exposure in adults with invasive fungal infections. Pharmacogenet Genomics (2017) 0.75

Prophylactic perioperative antibiotic administration: is it time to infuse our practices with new approaches? Anesth Analg (2015) 0.75

Basic research funding by philanthropic organizations: a case in point. Am J Respir Crit Care Med (2013) 0.75

Extended-spectrum beta-lactamases. Semin Respir Infect (2002) 0.75