| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group.
|
J Clin Oncol
|
2007
|
4.14
|
|
2
|
Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network.
|
Nat Cell Biol
|
2004
|
2.59
|
|
3
|
Protein kinase D: a family affair.
|
FEBS Lett
|
2003
|
2.09
|
|
4
|
Significantly improved precision of cell migration analysis in time-lapse video microscopy through use of a fully automated tracking system.
|
BMC Cell Biol
|
2010
|
2.04
|
|
5
|
Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells.
|
Nat Cell Biol
|
2003
|
1.84
|
|
6
|
Protein kinase D: an intracellular traffic regulator on the move.
|
Trends Cell Biol
|
2002
|
1.81
|
|
7
|
Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor-induced Nur77 expression and apoptosis.
|
J Exp Med
|
2005
|
1.72
|
|
8
|
IgG4-related autoimmune diseases: Polymorphous presentation complicates diagnosis and treatment.
|
Dtsch Arztebl Int
|
2015
|
1.70
|
|
9
|
Impact of tumor cell cytoskeleton organization on invasiveness and migration: a microchannel-based approach.
|
PLoS One
|
2010
|
1.43
|
|
10
|
Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours.
|
Gut
|
2010
|
1.32
|
|
11
|
Prognostic indicators of survival in patients with compensated and decompensated cirrhosis.
|
Liver Int
|
2012
|
1.29
|
|
12
|
Protein kinase D2 mediates activation of nuclear factor kappaB by Bcr-Abl in Bcr-Abl+ human myeloid leukemia cells.
|
Cancer Res
|
2004
|
1.28
|
|
13
|
Relative potency of proton-pump inhibitors-comparison of effects on intragastric pH.
|
Eur J Clin Pharmacol
|
2008
|
1.26
|
|
14
|
Molecular mechanisms of low intensity pulsed ultrasound in human skin fibroblasts.
|
J Biol Chem
|
2004
|
1.26
|
|
15
|
Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay.
|
J Cell Sci
|
2007
|
1.22
|
|
16
|
Modulation of calcium-activated potassium channels induces cardiogenesis of pluripotent stem cells and enrichment of pacemaker-like cells.
|
Circulation
|
2010
|
1.22
|
|
17
|
New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases.
|
Mol Cell Biol
|
2006
|
1.11
|
|
18
|
Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling.
|
Mol Biol Cell
|
2005
|
1.10
|
|
19
|
Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases.
|
Mol Biol Cell
|
2013
|
1.07
|
|
20
|
Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells.
|
J Cell Sci
|
2012
|
1.04
|
|
21
|
Current oncological treatment of patients with pancreatic cancer in germany: results from a national survey on behalf of the Arbeitsgemeinschaft Internistische Onkologie and the Chirurgische Arbeitsgemeinschaft Onkologie of the Germany Cancer Society.
|
Oncology
|
2009
|
1.03
|
|
22
|
The future role of the gastroenterologist in digestive oncology: an international perspective.
|
Gastroenterology
|
2011
|
1.01
|
|
23
|
Glial-derived neurotrophic factor regulates apoptosis in colonic epithelial cells.
|
Gastroenterology
|
2003
|
1.01
|
|
24
|
Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.
|
EMBO J
|
2007
|
1.00
|
|
25
|
Role of the second cysteine-rich domain and Pro275 in protein kinase D2 interaction with ADP-ribosylation factor 1, trans-Golgi network recruitment, and protein transport.
|
Mol Biol Cell
|
2010
|
0.99
|
|
26
|
TBX3 Directs Cell-Fate Decision toward Mesendoderm.
|
Stem Cell Reports
|
2013
|
0.98
|
|
27
|
Mechanism of activation of protein kinase D2(PKD2) by the CCK(B)/gastrin receptor.
|
J Biol Chem
|
2002
|
0.97
|
|
28
|
Protein kinase D1 mediates anchorage-dependent and -independent growth of tumor cells via the zinc finger transcription factor Snail1.
|
J Biol Chem
|
2012
|
0.96
|
|
29
|
Incorporating indocyanin green clearance into the Model for End Stage Liver Disease (MELD-ICG) improves prognostic accuracy in intermediate to advanced cirrhosis.
|
Gut
|
2010
|
0.95
|
|
30
|
Oxaliplatin in combination with 5-fluorouracil/leucovorin or capecitabine in elderly patients with metastatic colorectal cancer.
|
Clin Colorectal Cancer
|
2008
|
0.94
|
|
31
|
Targeted treatments in colorectal cancer: state of the art and future perspectives.
|
Gut
|
2010
|
0.94
|
|
32
|
Characterization of cortactin as an in vivo protein kinase D substrate: interdependence of sites and potentiation by Src.
|
Cell Signal
|
2008
|
0.92
|
|
33
|
Protein kinase D2 regulates chromogranin A secretion in human BON neuroendocrine tumour cells.
|
Cell Signal
|
2008
|
0.92
|
|
34
|
Gastrin transactivates the chromogranin A gene through MEK-1/ERK- and PKC-dependent phosphorylation of Sp1 and CREB.
|
Cell Signal
|
2007
|
0.92
|
|
35
|
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.
|
Neuro Oncol
|
2011
|
0.91
|
|
36
|
The phosphatase of regenerating liver 3 (PRL-3) promotes cell migration through Arf-activity-dependent stimulation of integrin α5 recycling.
|
J Cell Sci
|
2012
|
0.91
|
|
37
|
Regulation of cyclin D1 expression by autocrine IGF-I in human BON neuroendocrine tumour cells.
|
Oncogene
|
2005
|
0.90
|
|
38
|
Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis.
|
Am J Physiol Gastrointest Liver Physiol
|
2002
|
0.90
|
|
39
|
Focal adhesion kinase mediates defects in the force-dependent reinforcement of initial integrin-cytoskeleton linkages in metastatic colon cancer cell lines.
|
Eur J Cell Biol
|
2007
|
0.89
|
|
40
|
Propranolol impairs liver regeneration after partial hepatectomy in C57Bl/6-mice by transient attenuation of hepatic lipid accumulation and increased apoptosis.
|
Scand J Gastroenterol
|
2010
|
0.88
|
|
41
|
Protein kinase D regulates RhoA activity via rhotekin phosphorylation.
|
J Biol Chem
|
2012
|
0.88
|
|
42
|
Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export.
|
EMBO J
|
2013
|
0.87
|
|
43
|
The bioactive lipid sphingosylphosphorylcholine induces differentiation of mouse embryonic stem cells and human promyelocytic leukaemia cells.
|
Cell Signal
|
2006
|
0.87
|
|
44
|
Palliative treatment of pancreatic cancer.
|
J Dig Dis
|
2008
|
0.87
|
|
45
|
Elastic moduli of living epithelial pancreatic cancer cells and their skeletonized keratin intermediate filament network.
|
Biointerphases
|
2011
|
0.86
|
|
46
|
Telotristat etiprate for carcinoid syndrome: a single-arm, multicenter trial.
|
J Clin Endocrinol Metab
|
2015
|
0.85
|
|
47
|
The impact of bioactive lipids on cardiovascular development.
|
Stem Cells Int
|
2011
|
0.85
|
|
48
|
Novel approaches to target pancreatic cancer.
|
Curr Cancer Drug Targets
|
2011
|
0.85
|
|
49
|
A hierarchy in reprogramming capacity in different tissue microenvironments: what we know and what we need to know.
|
Stem Cells Dev
|
2013
|
0.85
|
|
50
|
Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: identification of two cleavage sites by microsequencing.
|
Cell Signal
|
2004
|
0.84
|
|
51
|
Definitive Endoderm Formation from Plucked Human Hair-Derived Induced Pluripotent Stem Cells and SK Channel Regulation.
|
Stem Cells Int
|
2013
|
0.84
|
|
52
|
Fecal transplant in refractory Clostridium difficile colitis.
|
Dtsch Arztebl Int
|
2013
|
0.83
|
|
53
|
Docetaxel, oxaliplatin and capecitabine (TEX regimen) in patients with metastatic gastric or gastro-esophageal cancer: results of a multicenter phase I/II study.
|
Acta Oncol
|
2013
|
0.82
|
|
54
|
Modelling human channelopathies using induced pluripotent stem cells: a comprehensive review.
|
Stem Cells Int
|
2013
|
0.82
|
|
55
|
Protein kinase D2 is an essential regulator of murine myoblast differentiation.
|
PLoS One
|
2011
|
0.81
|
|
56
|
Combination of antiangiogenic therapy using the mTOR-inhibitor everolimus and low-dose chemotherapy for locally advanced and/or metastatic pancreatic cancer: a dose-finding study.
|
Anticancer Drugs
|
2014
|
0.80
|
|
57
|
Clinical course of haemodialysis patients with malignancies and dose-adjusted chemotherapy.
|
Nephrol Dial Transplant
|
2005
|
0.80
|
|
58
|
Current Standard and Future Perspectives in First- and Second-Line Treatment of Metastatic Pancreatic Adenocarcinoma.
|
Digestion
|
2016
|
0.80
|
|
59
|
PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.
|
J Gastroenterol Hepatol
|
2014
|
0.80
|
|
60
|
Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population.
|
BMC Cancer
|
2011
|
0.79
|
|
61
|
Pre-study protocol MagPEP: a multicentre randomized controlled trial of magnesium sulphate in the prevention of post-ERCP pancreatitis.
|
BMC Gastroenterol
|
2013
|
0.79
|
|
62
|
Regorafenib.
|
Recent Results Cancer Res
|
2014
|
0.79
|
|
63
|
Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity.
|
Cell Signal
|
2007
|
0.78
|
|
64
|
Effects of keratin phosphorylation on the mechanical properties of keratin filaments in living cells.
|
FASEB J
|
2012
|
0.78
|
|
65
|
A prospective, non-randomized phase II trial of Trastuzumab and Capecitabine in patients with HER2 expressing metastasized pancreatic cancer.
|
BMC Surg
|
2009
|
0.78
|
|
66
|
A randomized multicentre phase II trial comparing adjuvant therapy in patients with interferon alpha-2b and 5-FU alone or in combination with either external radiation treatment and cisplatin (CapRI) or radiation alone regarding event-free survival - CapRI-2.
|
BMC Cancer
|
2009
|
0.78
|
|
67
|
A 25-year-old woman with a gastric GIST and a PET-positive epicardial tumor.
|
Nat Clin Pract Oncol
|
2007
|
0.78
|
|
68
|
HLA polymorphisms influence the development of skin rash arising from treatment with EGF receptor inhibitors.
|
Pharmacogenomics
|
2012
|
0.77
|
|
69
|
Surgical treatment concepts for patients with pancreatic cancer in Germany--results from a national survey conducted among members of the "Chirurgische Arbeitsgemeinschaft Onkologie" (CAO) and the "Arbeitsgemeinschaft Internistische Onkologie" (AIO) of the Germany Cancer Society (DKG).
|
Langenbecks Arch Surg
|
2010
|
0.77
|
|
70
|
Direct assessment of living cell mechanical responses during deformation inside microchannel restrictions.
|
Biointerphases
|
2011
|
0.77
|
|
71
|
Inflammation, regeneration, and transformation in the pancreas: results of the Collaborative Research Center 518 (SFB 518) at the University of Ulm.
|
Pancreas
|
2011
|
0.77
|
|
72
|
Different regulation of physiological and tumor angiogenesis in zebrafish by protein kinase D1 (PKD1).
|
PLoS One
|
2013
|
0.77
|
|
73
|
Rapid development of a hepatocellular carcinoma in isolated thrombosis of hepatic veins (classic Budd-Chiari syndrome): case report and review of literature.
|
BMJ Case Rep
|
2009
|
0.77
|
|
74
|
Nab-paclitaxel for metastatic pancreatic cancer: clinical outcomes and potential mechanisms of action.
|
Oncol Res Treat
|
2014
|
0.77
|
|
75
|
SR 57746A/xaliproden, a non-peptide neurotrophic compound: prospects and constraints for the treatment of nervous system diseases.
|
Expert Opin Investig Drugs
|
2009
|
0.76
|
|
76
|
Health care for osteoporosis in inflammatory bowel disease: unmet needs in care of male patients?
|
J Crohns Colitis
|
2013
|
0.75
|
|
77
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
|
78
|
In reply.
|
Dtsch Arztebl Int
|
2015
|
0.75
|
|
79
|
In Reply.
|
Dtsch Arztebl Int
|
2015
|
0.75
|
|
80
|
Ongoing colorectal cancer risk despite surveillance colonoscopy: the Polyp Prevention Trial Continued Follow-up Study.
|
Gastrointest Endosc
|
2010
|
0.75
|
|
81
|
IGF-1 drives chromogranin A secretion via activation of Arf1 in human neuroendocrine tumour cells.
|
J Cell Mol Med
|
2015
|
0.75
|
|
82
|
Gene regulatory biomarker identification for skin toxicities induced by EGFR inhibitor treatment.
|
Int J Clin Pharmacol Ther
|
2015
|
0.75
|
|
83
|
Surveillance after resection of pancreatic ductal adenocarcinoma with curative intent - a multicenter survey in Germany and review of the literature.
|
Z Gastroenterol
|
2017
|
0.75
|
|
84
|
Response to reintroduction of cetuximab in 5 patients with advanced, chemotherapy-resistant, colorectal cancer without progressive disease following first-line therapy with a cetuximab-containing regimen.
|
Oncology
|
2008
|
0.75
|
|
85
|
A phase I/II study of oxaliplatin and paclitaxel in patients with non-resectable cancer of the oesophagus and adenocarcinoma of the gastro-oesophageal junction: a study of the Arbeitsgemeinschaft Internistische Onkologie.
|
Cancer Chemother Pharmacol
|
2010
|
0.75
|
|
86
|
TBX3 Directs Cell-Fate Decision toward Mesendoderm.
|
Stem Cell Reports
|
2014
|
0.75
|
|
87
|
[Guidelines and expert consensus in the ZfG].
|
Z Gastroenterol
|
2014
|
0.75
|
|
88
|
Impaired bolus clearance in combined high-resolution esophageal manometry and impedance measurement helps to differentiate between esophagogastric junction outflow obstruction and achalasia.
|
Z Gastroenterol
|
2017
|
0.75
|
|
89
|
[Specific treatment situations in metastatic colorectal cancer].
|
Onkologie
|
2010
|
0.75
|
|
90
|
Electronic clinical challenges and images in GI. Pneumatosis cystoides intestinalis.
|
Gastroenterology
|
2008
|
0.75
|
|
91
|
[First-degree relatives of colorectal cancer patients: how many can we protect?].
|
Z Gastroenterol
|
2014
|
0.75
|
|
92
|
High Prognostic Value of Mini-Laparoscopy for Advanced Liver Disease-Related Complications in Patients with HCV Infection.
|
Digestion
|
2016
|
0.75
|
|
93
|
[Tonsillar actinomycosis as a rare cause of oral malodor. Diagnosis beyond a gastroenterologist's nose].
|
Med Klin (Munich)
|
2009
|
0.75
|
|
94
|
[Hope and disappointment in cancer medicine].
|
Z Arztl Fortbild Qualitatssich
|
2007
|
0.75
|
|
95
|
Phosphorylation and turnover of paxillin in focal contacts is controlled by force and defines the dynamic state of the adhesion site.
|
Cytoskeleton (Hoboken)
|
2015
|
0.75
|
|
96
|
[ZfG 2007: A successful interim result].
|
Z Gastroenterol
|
2007
|
0.75
|