| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo.
|
Nat Protoc
|
2009
|
4.47
|
|
2
|
HAGR: the Human Ageing Genomic Resources.
|
Nucleic Acids Res
|
2005
|
1.96
|
|
3
|
The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific.
|
Aging Cell
|
2013
|
1.56
|
|
4
|
Replicative aging down-regulates the myogenic regulatory factors in human myoblasts.
|
Biol Cell
|
2008
|
1.30
|
|
5
|
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.
|
J Cell Sci
|
2005
|
1.26
|
|
6
|
Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).
|
Ann N Y Acad Sci
|
2007
|
1.21
|
|
7
|
Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis.
|
Toxicol Appl Pharmacol
|
2010
|
1.17
|
|
8
|
GenAge: a genomic and proteomic network map of human ageing.
|
FEBS Lett
|
2004
|
1.17
|
|
9
|
Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts.
|
Free Radic Biol Med
|
2002
|
1.13
|
|
10
|
Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model.
|
Toxicol Lett
|
2011
|
1.08
|
|
11
|
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts.
|
Free Radic Biol Med
|
2008
|
1.08
|
|
12
|
Serum N-glycan profile shift during human ageing.
|
Exp Gerontol
|
2010
|
1.08
|
|
13
|
p38(MAPK) in the senescence of human and murine fibroblasts.
|
Adv Exp Med Biol
|
2010
|
1.04
|
|
14
|
UVB-induced premature senescence of human diploid skin fibroblasts.
|
Int J Biochem Cell Biol
|
2002
|
1.01
|
|
15
|
Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium.
|
Chem Biol Interact
|
2010
|
0.99
|
|
16
|
How bioinformatics can help reverse engineer human aging.
|
Ageing Res Rev
|
2004
|
0.99
|
|
17
|
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts.
|
FEBS Lett
|
2002
|
0.96
|
|
18
|
Role of TGF-beta1-independent changes in protein neosynthesis, p38alphaMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis.
|
Free Radic Biol Med
|
2008
|
0.96
|
|
19
|
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide.
|
Cell Stress Chaperones
|
2002
|
0.96
|
|
20
|
Impact of ageing on proteasome structure and function in human lymphocytes.
|
Int J Biochem Cell Biol
|
2003
|
0.95
|
|
21
|
Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A).
|
Biogerontology
|
2009
|
0.94
|
|
22
|
Normal or stress-induced fibroblast senescence involves COX-2 activity.
|
Exp Cell Res
|
2007
|
0.92
|
|
23
|
Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts.
|
FEBS Lett
|
2006
|
0.92
|
|
24
|
Establishment of H2O2-induced premature senescence in human fibroblasts concomitant with increased cellular production of H2O2.
|
Ann N Y Acad Sci
|
2006
|
0.90
|
|
25
|
Identification of 30 protein species involved in replicative senescence and stress-induced premature senescence.
|
FEBS Lett
|
2002
|
0.89
|
|
26
|
Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor.
|
PLoS One
|
2010
|
0.88
|
|
27
|
Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H(2)O(2)-induced premature senescence and interplay with p38alpha(MAPK).
|
FEBS Lett
|
2008
|
0.88
|
|
28
|
Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase.
|
Exp Gerontol
|
2004
|
0.86
|
|
29
|
Copper(II) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response.
|
Nanoscale
|
2012
|
0.86
|
|
30
|
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays.
|
FEBS Lett
|
2005
|
0.85
|
|
31
|
The evolution of mammalian aging.
|
Exp Gerontol
|
2002
|
0.84
|
|
32
|
Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts.
|
PLoS One
|
2009
|
0.83
|
|
33
|
Prematurely senescent ARPE-19 cells display features of age-related macular degeneration.
|
Free Radic Biol Med
|
2008
|
0.83
|
|
34
|
Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB.
|
Biogerontology
|
2003
|
0.83
|
|
35
|
Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol.
|
Biogerontology
|
2007
|
0.82
|
|
36
|
Serum IL-6 and IGF-1 improve clinical prediction of functional decline after hospitalization in older patients.
|
Aging Clin Exp Res
|
2010
|
0.82
|
|
37
|
Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence.
|
Ann N Y Acad Sci
|
2007
|
0.82
|
|
38
|
Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells.
|
Toxicol In Vitro
|
2010
|
0.82
|
|
39
|
The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype.
|
Exp Gerontol
|
2007
|
0.82
|
|
40
|
Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence.
|
Biochem Pharmacol
|
2002
|
0.82
|
|
41
|
Development of a PIXE analysis method for the determination of the biopersistence of SiC and TiC nanoparticles in rat lungs.
|
Nanotoxicology
|
2011
|
0.82
|
|
42
|
Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology.
|
Mech Ageing Dev
|
2007
|
0.81
|
|
43
|
Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: effects of sonication, dispersive agents and corneous layer of reconstructed epidermis.
|
Nanotoxicology
|
2010
|
0.81
|
|
44
|
Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications.
|
Toxicology
|
2009
|
0.81
|
|
45
|
No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.
|
Ann N Y Acad Sci
|
2004
|
0.80
|
|
46
|
Validation of the calibrated thrombin generation test (cTGT) as the reference assay to evaluate the procoagulant activity of nanomaterials.
|
Nanotoxicology
|
2011
|
0.80
|
|
47
|
Transcriptomic biomarkers of human ageing in peripheral blood mononuclear cell total RNA.
|
Exp Gerontol
|
2009
|
0.80
|
|
48
|
Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape.
|
Nanotoxicology
|
2011
|
0.79
|
|
49
|
Biological models for phytochemical research: from cell to human organism.
|
Br J Nutr
|
2008
|
0.79
|
|
50
|
Role of the PLA2-independent peroxiredoxin VI activity in the survival of immortalized fibroblasts exposed to cytotoxic oxidative stress.
|
FEBS Lett
|
2004
|
0.79
|
|
51
|
Proteomics in experimental gerontology.
|
Exp Gerontol
|
2002
|
0.78
|
|
52
|
High-resolution quantitative metabolome analysis of urine by automated flow injection NMR.
|
Anal Chem
|
2013
|
0.78
|
|
53
|
Upregulation of annexin A2 in H(2)O(2)-induced premature senescence as evidenced by 2D-DIGE proteome analysis.
|
Exp Gerontol
|
2008
|
0.78
|
|
54
|
Role of p38MAPK and oxidative stress in copper-induced senescence.
|
Age (Dordr)
|
2013
|
0.77
|
|
55
|
Transient increased extracellular release of H2O2 during establishment of UVB-induced premature senescence.
|
Ann N Y Acad Sci
|
2007
|
0.77
|
|
56
|
Pro-inflammatory effects of different MWCNTs dispersions in p16(INK4A)-deficient telomerase-expressing human keratinocytes but not in human SV-40 immortalized sebocytes.
|
Nanotoxicology
|
2011
|
0.77
|
|
57
|
Quantification of nanoparticles in aqueous food matrices using Particle-Induced X-ray Emission.
|
Anal Bioanal Chem
|
2012
|
0.77
|
|
58
|
Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture.
|
Mech Ageing Dev
|
2011
|
0.77
|
|
59
|
Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence.
|
Int J Biochem Cell Biol
|
2003
|
0.77
|
|
60
|
Effects of SiC nanoparticles orally administered in a rat model: biodistribution, toxicity and elemental composition changes in feces and organs.
|
Toxicol Appl Pharmacol
|
2012
|
0.76
|
|
61
|
Exposure of human skin diploid fibroblasts to repeated subcytotoxic doses of ultraviolet-B induces the overexpression of transforming growth factor-beta1 mRNA.
|
Ann N Y Acad Sci
|
2002
|
0.76
|
|
62
|
Telomeres and telomerase: a modern fountain of youth?
|
Rejuvenation Res
|
2004
|
0.76
|
|
63
|
Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases.
|
Immun Ageing
|
2010
|
0.76
|
|
64
|
UV, stress and aging.
|
Dermatoendocrinol
|
2012
|
0.76
|
|
65
|
Expression profiling of senescent-associated genes in human dermis from young and old donors. Proof-of-concept study.
|
Biogerontology
|
2008
|
0.76
|
|
66
|
The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis.
|
Toxicology
|
2007
|
0.76
|
|
67
|
High throughput 'omics' approaches to assess the effects of phytochemicals in human health studies.
|
Br J Nutr
|
2008
|
0.75
|
|
68
|
p53 and ATF-2 partly mediate the overexpression of COX-2 in H(2)O (2)-induced premature senescence of human fibroblasts.
|
Biogerontology
|
2008
|
0.75
|
|
69
|
A comparison of six major platelet functional tests to assess the impact of carbon nanomaterials on platelet function: a practical guide.
|
Nanotoxicology
|
2013
|
0.75
|
|
70
|
Informed consent of very old patients and modern genomics.
|
Biogerontology
|
2005
|
0.75
|
|
71
|
View of a young biogerontologist on the in vitro biogerontological model systems.
|
Exp Gerontol
|
2003
|
0.75
|
|
72
|
LINK-AGE: coordination and consolidation of European biogerontology: en route towards formation of a European college of biogerontology.
|
Mech Ageing Dev
|
2006
|
0.75
|
|
73
|
Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls.
|
Exp Gerontol
|
2010
|
0.75
|