Confounding by linkage disequilibrium.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 3970903)

Published in J Hum Genet on December 19, 2013

Authors

Brahim Aissani1

Author Affiliations

1: Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.

Articles cited by this

Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet (1962) 13.72

Mitochondrial diseases in man and mouse. Science (1999) 11.67

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat Genet (2002) 8.19

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics (2010) 7.07

The evolutionary dynamics of eukaryotic gene order. Nat Rev Genet (2004) 5.79

Deletion of ultraconserved elements yields viable mice. PLoS Biol (2007) 4.81

Definition and properties of disequilibrium statistics for associations between nuclear and cytoplasmic genotypes. Genetics (1987) 3.96

The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nat Rev Genet (2011) 3.57

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37

Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet (2010) 3.02

The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study. Am J Epidemiol (2011) 2.98

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73

The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI. Obesity (Silver Spring) (2009) 2.34

Influence of body size and body fat distribution on risk of uterine leiomyomata in U.S. black women. Epidemiology (2005) 2.33

An improper use of statistical significance testing in studying covariables. Int J Epidemiol (1978) 2.24

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12

Childhood obesity and the timing of puberty. Trends Endocrinol Metab (2009) 2.00

Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants. Nat Genet (2006) 1.92

One hundred years of pleiotropy: a retrospective. Genetics (2010) 1.91

Toward a molecular understanding of pleiotropy. Genetics (2006) 1.88

The meaning of interaction. Hum Hered (2010) 1.83

Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies. Diabetes (2010) 1.70

Epidemiologic contributions to understanding the etiology of uterine leiomyomata. Environ Health Perspect (2000) 1.69

Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response. PLoS Biol (2010) 1.61

Multiple hits for the association of uterine fibroids on human chromosome 1q43. PLoS One (2013) 1.50

Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43. Am J Hum Genet (2001) 1.42

Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors. Am J Pathol (2004) 1.37

Association of physical activity with development of uterine leiomyoma. Am J Epidemiol (2006) 1.27

Involvement of fumarate hydratase in nonsyndromic uterine leiomyomas: genetic linkage analysis and FISH studies. Genes Chromosomes Cancer (2004) 1.19

Growth factors and cytokines in uterine leiomyomas. Semin Reprod Endocrinol (1996) 1.17

Genome-wide linkage scan reveals multiple susceptibility loci influencing lipid and lipoprotein levels in the Quebec Family Study. J Lipid Res (2003) 1.13

A quantitative trait locus for body fat on chromosome 1q43 in French Canadians: linkage and association studies. Obesity (Silver Spring) (2006) 0.95

Relation of energy, fat, and fiber intakes to plasma concentrations of estrogens and androgens in premenopausal women. Am J Clin Nutr (1996) 0.94

Energy metabolism and the evolution of reproductive suppression in the human female. Acta Biotheor (2003) 0.94

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. Am J Epidemiol (2013) 0.93

A genome-wide linkage scan for steroids and SHBG levels in black and white families: the HERITAGE Family Study. J Clin Endocrinol Metab (2002) 0.91

Genome-wide linkage and peak-wide association study of obesity-related quantitative traits in Caribbean Hispanics. Hum Genet (2010) 0.89

Piecing together the FTO jigsaw. Genome Biol (2011) 0.86

Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms. Genetics (2012) 0.79