Published in Anal Chem on January 15, 2014
Acetyl Fentanyl, a Novel Fentanyl Analog, Causes 14 Overdose Deaths in Rhode Island, March-May 2013. J Med Toxicol (2015) 0.95
Measurement of serum acetaminophen-protein adducts in patients with acute liver failure. Gastroenterology (2006) 3.85
Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids. Prog Neuropsychopharmacol Biol Psychiatry (2012) 2.87
Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure. Hepatology (2011) 2.61
Mechanisms of acetaminophen-induced liver necrosis. Handb Exp Pharmacol (2010) 2.54
Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection. Drug Metab Dispos (2002) 2.34
Smooth muscle cell plasticity: fact or fiction? Circ Res (2012) 2.18
Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity. PLoS One (2011) 1.69
Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition. Drug Metab Rev (2004) 1.65
Upregulation of L-type Ca2+ channels in mesenteric and skeletal arteries of SHR. Hypertension (2002) 1.49
Translational biomarkers of acetaminophen-induced acute liver injury. Arch Toxicol (2015) 1.49
High blood pressure upregulates arterial L-type Ca2+ channels: is membrane depolarization the signal? Circ Res (2004) 1.47
Decreased endothelin binding and [Ca2+]i signaling in microvessels of DOCA-salt hypertensive rats. J Hypertens (2002) 1.46
Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. Anal Chem (2011) 1.45
Voltage-gated K+ channels in rat small cerebral arteries: molecular identity of the functional channels. J Physiol (2003) 1.44
Regulation of arterial tone by KV1 potassium channels. Circ Res (2005) 1.43
Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands. Drug Metab Dispos (2012) 1.41
A rare ingestion of the Black Locust tree. J Toxicol Clin Toxicol (2004) 1.39
Compounded ointment results in severe toxicity in a pediatric patient. Pediatr Emerg Care (2013) 1.38
Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase. J Pharmacol Exp Ther (2010) 1.38
Marijuana-based drugs: innovative therapeutics or designer drugs of abuse? Mol Interv (2011) 1.38
Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury. Kidney Int (2011) 1.33
Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. Biochem Pharmacol (2012) 1.32
Vascular calcium channels and high blood pressure: pathophysiology and therapeutic implications. Vascul Pharmacol (2006) 1.31
Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine. Anal Chem (2011) 1.27
Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury. Am J Pathol (2011) 1.27
MDMA use and neurocognition: a meta-analytic review. Psychopharmacology (Berl) (2006) 1.26
Acetaminophen-cysteine adducts during therapeutic dosing and following overdose. BMC Gastroenterol (2011) 1.26
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset. J Neurochem (2007) 1.24
Population pharmacokinetics of metronidazole evaluated using scavenged samples from preterm infants. Antimicrob Agents Chemother (2012) 1.23
New expression profiles of voltage-gated ion channels in arteries exposed to high blood pressure. Microcirculation (2002) 1.22
The value of nonhuman primates in drug abuse research. Exp Clin Psychopharmacol (2007) 1.19
Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys. Neuropsychopharmacology (2009) 1.18
Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds. Forensic Sci Int (2013) 1.16
Vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity. Am J Physiol Gastrointest Liver Physiol (2006) 1.12
Not simply synthetic tetrahydrocannabinol. J Pediatr (2013) 1.12
Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases. Drug Metab Dispos (2011) 1.11
Upregulation of vascular calcium channels in neonatal piglets with hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2008) 1.11
Population pharmacokinetics of piperacillin using scavenged samples from preterm infants. Ther Drug Monit (2012) 1.04
Freshly isolated bovine coronary endothelial cells do not express the BK Ca channel gene. J Physiol (2002) 1.04
Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans. Am J Clin Nutr (2010) 1.04
A fatality involving an unusual route of fentanyl delivery: Chewing and aspirating the transdermal patch. Leg Med (Tokyo) (2010) 1.02
Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases. J Pharmacol Exp Ther (2007) 1.01
Evaluation of the Mercy TAPE: performance against the standard for pediatric weight estimation. Ann Emerg Med (2013) 0.97
Nitration and functional loss of voltage-gated K+ channels in rat coronary microvessels exposed to high glucose. Diabetes (2004) 0.97
Differential drug-drug interactions of the synthetic Cannabinoids JWH-018 and JWH-073: implications for drug abuse liability and pain therapy. J Pharmacol Exp Ther (2013) 0.95
Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids. Drug Metab Dispos (2009) 0.95
Intracellular Ca2+ silences L-type Ca2+ channels in mesenteric veins: mechanism of venous smooth muscle resistance to calcium channel blockers. Circ Res (2009) 0.94
Photoacoustic and photothermal detection of circulating tumor cells, bacteria and nanoparticles in cerebrospinal fluid in vivo and ex vivo. J Biophotonics (2013) 0.94
Quantitative measurement of urinary excretion of 3-hydroxyisovaleryl carnitine by LC-MS/MS as an indicator of biotin status in humans. Anal Chem (2010) 0.93
Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors. Toxicol Appl Pharmacol (2013) 0.93
Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children. Biomark Med (2014) 0.93
Starring TREK-1: the next generation of vascular K+ channels. Circ Res (2007) 0.92
A serotonin-induced N-glycan switch regulates platelet aggregation. Sci Rep (2013) 0.92
Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity. J Pharmacol Exp Ther (2010) 0.92
The β3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice. Hypertension (2012) 0.91
Escalation of food-maintained responding and sensitivity to the locomotor stimulant effects of cocaine in mice. Pharmacol Biochem Behav (2009) 0.91
Omeprazole disposition in children following single-dose administration. J Clin Pharmacol (2003) 0.90
A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors. Chem Res Toxicol (2012) 0.90
Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice. J Pharmacol Exp Ther (2011) 0.90
Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia. Toxicol Appl Pharmacol (2011) 0.90
Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans. J Nutr (2011) 0.90
Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin. Chem Res Toxicol (2010) 0.90
Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans. Chem Res Toxicol (2009) 0.90
UGT1A9, UGT2B7, and MRP2 genotypes can predict mycophenolic acid pharmacokinetic variability in pediatric kidney transplant recipients. Ther Drug Monit (2012) 0.90
Postsynaptic density-95 scaffolding of Shaker-type K⁺ channels in smooth muscle cells regulates the diameter of cerebral arteries. J Physiol (2011) 0.89
AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: implications for opioid/cannabinoid interaction studies. Neuropharmacology (2012) 0.89
Synthetic studies and pharmacological evaluations on the MDMA ('Ecstasy') antagonist nantenine. Bioorg Med Chem Lett (2009) 0.89
Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors. Xenobiotica (2011) 0.88
Notes from the Field: Cardiac Dysrhythmias After Loperamide Abuse - New York, 2008-2016. MMWR Morb Mortal Wkly Rep (2016) 0.88
U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevance. Am J Physiol Heart Circ Physiol (2005) 0.87
Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial. Pediatr Crit Care Med (2012) 0.87
K2 toxicity: fatal case of psychiatric complications following AM2201 exposure. J Forensic Sci (2013) 0.87
The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network. PLoS One (2009) 0.86
Profound metabolic acidosis and oxoprolinuria in an adult. J Med Toxicol (2007) 0.86
Linoleic acid epoxide promotes the maintenance of mitochondrial function and active Na+ transport following hypoxia. Toxicol Lett (2004) 0.86
Prescription-acquired acetaminophen use and the risk of asthma in adults: a case-control study. Ann Pharmacother (2012) 0.86