Published in Front Physiol on December 19, 2013
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The sodium bicarbonate cotransporter (NBCe1) is essential for normal development of mouse dentition. J Biol Chem (2010) 1.25
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IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway. J Clin Invest (2011) 1.18
Structural organization of the human NBC1 gene: kNBC1 is transcribed from an alternative promoter in intron 3. Gene (2000) 1.18
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Direct extracellular interaction between carbonic anhydrase IV and the human NBC1 sodium/bicarbonate co-transporter. Biochemistry (2003) 1.17
Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine. Proc Natl Acad Sci U S A (2010) 1.14
A cysteine-scanning mutagenesis study of transmembrane domain 8 of the electrogenic sodium/bicarbonate cotransporter NBCe1. J Biol Chem (2006) 1.13
Proximal renal tubular acidosis and ocular pathology: a novel missense mutation in the gene (SLC4A4) for sodium bicarbonate cotransporter protein (NBCe1). Mol Vis (2006) 1.13
Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. J Physiol (2004) 1.11
Reversible and irreversible interactions of DIDS with the human electrogenic Na/HCO3 cotransporter NBCe1-A: role of lysines in the KKMIK motif of TM5. Am J Physiol Cell Physiol (2007) 1.11
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Phosphorylation of Ser(982) in the sodium bicarbonate cotransporter kNBC1 shifts the HCO(3)(-) : Na(+) stoichiometry from 3 : 1 to 2 : 1 in murine proximal tubule cells. J Physiol (2001) 1.09
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Relief of autoinhibition of the electrogenic Na-HCO(3) [corrected] cotransporter NBCe1-B: role of IRBIT vs.amino-terminal truncation. Am J Physiol Cell Physiol (2011) 1.04
The renal Na-HCO3-cotransporter expressed in Xenopus laevis oocytes: change in stoichiometry in response to elevation of cytosolic Ca2+ concentration. Pflugers Arch (2001) 1.04
Identification of residues lining the translocation pore of human AE1, plasma membrane anion exchange protein. J Biol Chem (1999) 1.03
Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis. J Biol Chem (2010) 1.02
Functional analysis of a novel missense NBC1 mutation and of other mutations causing proximal renal tubular acidosis. Pflugers Arch (2007) 1.02
Regulation of the sodium bicarbonate cotransporter kNBC1 function: role of Asp(986), Asp(988) and kNBC1-carbonic anhydrase II binding. J Physiol (2002) 1.01
NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway. J Biol Chem (2009) 1.00
Evidence against a direct interaction between intracellular carbonic anhydrase II and pure C-terminal domains of SLC4 bicarbonate transporters. J Biol Chem (2006) 0.97
Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na+-HCO3- cotransporters family. Proc Natl Acad Sci U S A (2013) 0.97
Cloning and identification of two novel NBCe1 splice variants from mouse reproductive tract tissues: a comparative study of NCBT genes. Genomics (2011) 0.95
Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A. J Biol Chem (2010) 0.94
Mutation of Aspartate 555 of the Sodium/Bicarbonate Transporter SLC4A4/NBCe1 Induces Chloride Transport. J Biol Chem (2009) 0.94
The Na(+)-HCO3- cotransporter operates with a coupling ratio of 2 HCO3- to 1 Na+ in isolated rabbit renal proximal tubule. Pflugers Arch (1993) 0.94
Severe metabolic acidosis causes early lethality in NBC1 W516X knock-in mice as a model of human isolated proximal renal tubular acidosis. Kidney Int (2011) 0.93
Role of an extracellular loop in determining the stoichiometry of Na+-HCO₃⁻ cotransporters. J Physiol (2011) 0.92
Molecular mechanisms of electrogenic sodium bicarbonate cotransport: structural and equilibrium thermodynamic considerations. J Membr Biol (2004) 0.92
Identification of a carboxyl-terminal motif essential for the targeting of Na+-HCO-3 cotransporter NBC1 to the basolateral membrane. J Biol Chem (2004) 0.92
Chaperone stress 70 protein (STCH) binds and regulates two acid/base transporters NBCe1-B and NHE1. J Biol Chem (2013) 0.92
Acid-base transport by the renal proximal tubule. J Nephrol (2010) 0.91
The renal Na-HCO3-cotransporter expressed in Xenopus laevis oocytes: inhibition by tenidap and benzamil and effect of temperature on transport rate and stoichiometry. Pflugers Arch (2001) 0.90
Phosphatidylinositol 4,5-bisphosphate (PIP2) stimulates the electrogenic Na/HCO3 cotransporter NBCe1-A expressed in Xenopus oocytes. Proc Natl Acad Sci U S A (2009) 0.89
Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydrase. PLoS One (2011) 0.87
Transport activity of chimaeric AE2-AE3 chloride/bicarbonate anion exchange proteins. Biochem J (2003) 0.87
Acid and mineral balances and bone in familial proximal renal tubular acidosis. Kidney Int (2000) 0.87
Binding of carbonic anhydrase IX to extracellular loop 4 of the NBCe1 Na+/HCO3- cotransporter enhances NBCe1-mediated HCO3- influx in the rat heart. Am J Physiol Cell Physiol (2012) 0.86
Electrophysiological characterization of native Na+-HCO3- cotransporter current in bovine parotid acinar cells. J Physiol (2005) 0.86
The electrogenic Na+-HCO3- cotransporter NBCe1-B is regulated by intracellular Mg2+. Biochem Biophys Res Commun (2008) 0.85
HCO(3)(-)-independent conductance with a mutant Na(+)/HCO(3)(-) cotransporter (SLC4A4) in a case of proximal renal tubular acidosis with hypokalaemic paralysis. J Physiol (2012) 0.85
Topology of NBCe1 protein transmembrane segment 1 and structural effect of proximal renal tubular acidosis (pRTA) S427L mutation. J Biol Chem (2013) 0.85
Determination of membrane protein transporter oligomerization in native tissue using spatial fluorescence intensity fluctuation analysis. PLoS One (2012) 0.84
Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na+ -HCO₃- cotransporter NBCe1 expressed in Xenopus oocytes. Channels (Austin) (2011) 0.83
Change of apparent stoichiometry of proximal-tubule Na(+)-HCO3- cotransport upon experimental reversal of its orientation. Proc Natl Acad Sci U S A (1993) 0.83
IRBIT reduces the apparent affinity for intracellular Mg²⁺ in inhibition of the electrogenic Na⁺-HCO₃⁻ cotransporter NBCe1-B. Biochem Biophys Res Commun (2012) 0.82
PIP2 hydrolysis stimulates the electrogenic Na+-bicarbonate cotransporter NBCe1-B and -C variants expressed in Xenopus laevis oocytes. J Physiol (2012) 0.81
Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na+-HCO3- cotransporter NBCe1A. Pflugers Arch (2011) 0.81
pH-sensitive self-associations of the N-terminal domain of NBCe1-A suggest a compact conformation under acidic intracellular conditions. Protein Pept Lett (2012) 0.81
G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. Am J Physiol Renal Physiol (2008) 0.80
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Effect of simultaneously replacing putative TM6 and TM12 of human NBCe1-A with those from NBCn1 on surface abundance in Xenopus oocytes. J Membr Biol (2012) 0.79
Identification of dominant negative effect of L522P mutation in the electrogenic Na⁺-HCO₃⁻ cotransporter NBCe1. Pflugers Arch (2013) 0.78