Published in Mar Drugs on January 07, 2014
Protective effects of astaxanthin on ConA-induced autoimmune hepatitis by the JNK/p-JNK pathway-mediated inhibition of autophagy and apoptosis. PLoS One (2015) 0.92
Biological roles of fungal carotenoids. Curr Genet (2014) 0.90
Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep (2015) 0.88
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice. Mar Drugs (2015) 0.87
Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application. J Nutr Metab (2015) 0.85
Astaxanthin-Producing Green Microalga Haematococcus pluvialis: From Single Cell to High Value Commercial Products. Front Plant Sci (2016) 0.85
Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants. Int J Mol Sci (2015) 0.84
Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis. Nutrients (2016) 0.84
Astaxanthin from Haematococcus pluvialis Prevents Oxidative Stress on Human Endothelial Cells without Toxicity. Mar Drugs (2015) 0.83
Astaxanthin as a Potential Neuroprotective Agent for Neurological Diseases. Mar Drugs (2015) 0.82
Chlorella zofingiensis as an alternative microalgal producer of astaxanthin: biology and industrial potential. Mar Drugs (2014) 0.82
DNA microarray-based experimental strategy for trustworthy expression profiling of the hippocampal genes by astaxanthin supplementation in adult mouse. Genom Data (2015) 0.80
Bioactive compounds from macroalgae in the new millennium: implications for neurodegenerative diseases. Mar Drugs (2014) 0.79
Astaxanthin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells via Inhibition of Nf-Κb P65 and Wnt/Β-Catenin in Vitro. Mar Drugs (2015) 0.79
Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission. J Cell Mol Med (2015) 0.78
In Vivo Effects of Free Form Astaxanthin Powder on Anti-Oxidation and Lipid Metabolism with High-Cholesterol Diet. PLoS One (2015) 0.78
Characterization of Shrimp Oil from Pandalus borealis by High Performance Liquid Chromatography and High Resolution Mass Spectrometry. Mar Drugs (2015) 0.78
Anti-inflammatory Effect of Astaxanthin on the Sickness Behavior Induced by Diabetes Mellitus. Cell Mol Neurobiol (2015) 0.78
Carotenoids from Haloarchaea and Their Potential in Biotechnology. Mar Drugs (2015) 0.77
Free Radical Scavenging and Cellular Antioxidant Properties of Astaxanthin. Int J Mol Sci (2016) 0.77
Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease. Int J Mol Sci (2016) 0.77
Intracellular redox state as target for anti-influenza therapy: are antioxidants always effective? Curr Top Med Chem (2014) 0.77
Evaluation of hepatoprotective and antioxidant activity of astaxanthin and astaxanthin esters from microalga-Haematococcus pluvialis. J Food Sci Technol (2015) 0.77
Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects. Front Microbiol (2017) 0.77
In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity. J Immunol Res (2016) 0.76
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Astaxanthin Inhibits Proliferation and Induces Apoptosis and Cell Cycle Arrest of Mice H22 Hepatoma Cells. Med Sci Monit (2016) 0.75
Potential Anti-Atherosclerotic Properties of Astaxanthin. Mar Drugs (2016) 0.75
A Combination of Flaxseed Oil and Astaxanthin Improves Hepatic Lipid Accumulation and Reduces Oxidative Stress in High Fat-Diet Fed Rats. Nutrients (2017) 0.75
Preventive effect of dietary astaxanthin on UVA-induced skin photoaging in hairless mice. PLoS One (2017) 0.75
Effects of astaxanthin on oxidative stress induced by Cu(2+) in prostate cells. J Zhejiang Univ Sci B (2017) 0.75
Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments. Nutrients (2017) 0.75
Astaxanthin protects against early burn-wound progression in rats by attenuating oxidative stress-induced inflammation and mitochondria-related apoptosis. Sci Rep (2017) 0.75
Progress in Microbial Carotenoids Production. Indian J Microbiol (2017) 0.75
Biocompatible astaxanthin as a novel marine-oriented agent for dual chemo-photothermal therapy. PLoS One (2017) 0.75
Plant cell culture strategies for the production of natural products. BMB Rep (2016) 0.75
Formulation of a fish feed for goldfish with natural astaxanthin extracted from shrimp waste. Chem Cent J (2016) 0.75
Improved Hepatoprotective Effect of Liposome-Encapsulated Astaxanthin in Lipopolysaccharide-Induced Acute Hepatotoxicity. Int J Mol Sci (2016) 0.75
Marine Microbial-Derived Molecules and Their Potential Use in Cosmeceutical and Cosmetic Products. Mar Drugs (2017) 0.75
Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration. Geroscience (2017) 0.75
Astaxanthin alleviates cerebral edema by modulating NKCC1 and AQP4 expression after traumatic brain injury in mice. BMC Neurosci (2016) 0.75
Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis. Stem Cell Res Ther (2017) 0.75
Effects of Dietary Inclusion of Astaxanthin on Growth, Muscle Pigmentation and Antioxidant Capacity of Juvenile Rainbow Trout (Oncorhynchus mykiss). Prev Nutr Food Sci (2016) 0.75
A Combination of Soybean and Haematococcus Extract Alleviates Ultraviolet B-Induced Photoaging. Int J Mol Sci (2017) 0.75
Mussel processing wastewater: a low-cost substrate for the production of astaxanthin by Xanthophyllomyces dendrorhous. Microb Cell Fact (2015) 0.75
Comparative genomics provides new insights into the diversity, physiology, and sexuality of the only industrially exploited tremellomycete: Phaffia rhodozyma. BMC Genomics (2016) 0.75
Maternal allocation of carotenoids increases tolerance to bacterial infection in brown trout. Oecologia (2017) 0.75
Astaxanthin stability and color change of krill during subcritical water treatment. J Food Sci Technol (2017) 0.75
Rapid Estimation of Astaxanthin and the Carotenoid-to-Chlorophyll Ratio in the Green Microalga Chromochloris zofingiensis Using Flow Cytometry. Mar Drugs (2017) 0.75
A sub-chronic toxicity evaluation of a natural astaxanthin-rich carotenoid extract of Paracoccus carotinifaciens in rats. Toxicol Rep (2014) 0.75
Haematococcus astaxanthin: applications for human health and nutrition. Trends Biotechnol (2003) 2.56
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Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae. Mol Nutr Food Res (2010) 1.52
Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease. Am J Cardiol (2008) 1.36
Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Invest Ophthalmol Vis Sci (2003) 1.32
Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutr Metab (Lond) (2010) 1.29
Inhibition of low-density lipoprotein oxidation by astaxanthin. J Atheroscler Thromb (2000) 1.21
Astaxanthin: a potential therapeutic agent in cardiovascular disease. Mar Drugs (2011) 1.19
Suppressive effects of astaxanthin against rat endotoxin-induced uveitis by inhibiting the NF-kappaB signaling pathway. Exp Eye Res (2005) 1.18
Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antiperoxidative activity of the carotenoid astaxanthin. Biochim Biophys Acta (2001) 1.18
Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice. Biofactors (2004) 1.16
Antihypertensive and neuroprotective effects of astaxanthin in experimental animals. Biol Pharm Bull (2005) 1.14
Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action. Carcinogenesis (1991) 1.13
Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis (2009) 1.12
Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year. Ophthalmology (2007) 1.10
Immunomodulating actions of carotenoids: enhancement of in vivo and in vitro antibody production to T-dependent antigens. Nutr Cancer (1994) 1.10
Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunol Lett (1999) 1.10
Safety of an astaxanthin-rich Haematococcus pluvialis algal extract: a randomized clinical trial. J Med Food (2003) 1.10
A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res (1999) 1.05
Antitumor activity of astaxanthin and its mode of action. Nutr Cancer (2000) 1.04
Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells. Cancer Lett (2009) 1.03
Neuroprotective effect of astaxanthin on H(2)O(2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo. Brain Res (2010) 1.01
Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev (2011) 1.01
Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling. J Cell Biochem (2008) 1.00
Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice. Redox Rep (2002) 0.99
Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin. Carcinogenesis (1994) 0.99
An efficient method for extraction of astaxanthin from green alga Haematococcus pluvialis. J Agric Food Chem (2006) 0.99
Astaxanthin-rich extract from the green alga Haematococcus pluvialis lowers plasma lipid concentrations and enhances antioxidant defense in apolipoprotein E knockout mice. J Nutr (2011) 0.98
Studies of immunomodulating actions of carotenoids. I. Effects of beta-carotene and astaxanthin on murine lymphocyte functions and cell surface marker expression in in vitro culture system. Nutr Cancer (1991) 0.97
Carotenoids up-regulate connexin43 gene expression independent of their provitamin A or antioxidant properties. Cancer Res (1992) 0.95
Effects of astaxanthin supplementation on lipid peroxidation. Int J Vitam Nutr Res (2007) 0.94
Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin and canthaxanthin. Cancer Res (1995) 0.93
Protective effect of astaxanthin on naproxen-induced gastric antral ulceration in rats. Eur J Pharmacol (2005) 0.93
Protective effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation on ultraviolet-induced skin damage. J Pharm Sci (2012) 0.93
Astaxanthin reduces hepatic endoplasmic reticulum stress and nuclear factor-κB-mediated inflammation in high fructose and high fat diet-fed mice. Cell Stress Chaperones (2013) 0.93
Identification of carotenoids from green alga Haematococcus pluvialis by HPLC and LC-MS (APCI) and their antioxidant properties. J Microbiol Biotechnol (2009) 0.92
On the relative efficiency of two- vs. one-stage production of astaxanthin by the green alga Haematococcus pluvialis. Biotechnol Bioeng (2007) 0.92
Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. Br J Nutr (2011) 0.90
Cosmetic benefits of astaxanthin on humans subjects. Acta Biochim Pol (2012) 0.90
Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomised, double-blind, placebo-controlled study. J Clin Biochem Nutr (2012) 0.90
Characterization of microalgal carotenoids by mass spectrometry and their bioavailability and antioxidant properties elucidated in rat model. J Agric Food Chem (2010) 0.90
Effective inhibition of skin cancer, tyrosinase, and antioxidative properties by astaxanthin and astaxanthin esters from the green alga Haematococcus pluvialis. J Agric Food Chem (2013) 0.89
Astaxanthin attenuates the apoptosis of retinal ganglion cells in db/db mice by inhibition of oxidative stress. Mar Drugs (2013) 0.89
Safety assessment of astaxanthin-rich microalgae biomass: Acute and subchronic toxicity studies in rats. Food Chem Toxicol (2008) 0.88
Characterization of astaxanthin pigments from heat-processed crawfish waste. J Agric Food Chem (1981) 0.88
Plasma appearance and distribution of astaxanthin E/Z and R/S isomers in plasma lipoproteins of men after single dose administration of astaxanthin. J Nutr Biochem (2000) 0.88
Oral bioavailability of the antioxidant astaxanthin in humans is enhanced by incorporation of lipid based formulations. Eur J Pharm Sci (2003) 0.87
Cis astaxanthin and especially 9-cis astaxanthin exhibits a higher antioxidant activity in vitro compared to the all-trans isomer. Biochem Biophys Res Commun (2007) 0.87
Seven day oral supplementation with Cardax (disodium disuccinate astaxanthin) provides significant cardioprotection and reduces oxidative stress in rats. Mol Cell Biochem (2006) 0.87
Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. J Pharmacol Exp Ther (2005) 0.87
Effect of astaxanthin in combination with alpha-tocopherol or ascorbic acid against oxidative damage in diabetic ODS rats. J Nutr Sci Vitaminol (Tokyo) (2008) 0.86
Protection against oxidative stress, inflammation, and apoptosis of high-glucose-exposed proximal tubular epithelial cells by astaxanthin. J Agric Food Chem (2009) 0.86
Astaxanthin ameliorates features of metabolic syndrome in SHR/NDmcr-cp. Life Sci (2006) 0.86
High-titer production of astaxanthin by the semi-industrial fermentation of Xanthophyllomyces dendrorhous. J Biotechnol (2010) 0.86
Astaxanthin prevents changes in the activities of thioredoxin reductase and paraoxonase in hypercholesterolemic rabbits. J Clin Biochem Nutr (2012) 0.86
Retinoids and carotenoids as inhibitors of carcinogenesis and inducers of cell-cell communication. Nutr Rev (1992) 0.85
Ulcer preventive and antioxidative properties of astaxanthin from Haematococcus pluvialis. Eur J Pharmacol (2008) 0.85
Protective effects of astaxanthin from Paracoccus carotinifaciens on murine gastric ulcer models. Phytother Res (2011) 0.84
Cytoprotective role of astaxanthin against glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells. Phytother Res (2010) 0.84
Impact of divergent effects of astaxanthin on insulin signaling in L6 cells. Endocrinology (2013) 0.84
Anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of nitroastaxanthin and nitrolutein, the reaction products of astaxanthin and lutein with peroxynitrite. Mar Drugs (2012) 0.84
Bioavailability of astaxanthin in Haematococcus algal extract: the effects of timing of diet and smoking habits. Biosci Biotechnol Biochem (2009) 0.84
Effect of dietary astaxanthin at different stages of mammary tumor initiation in BALB/c mice. Anticancer Res (2010) 0.84
Tissue distribution of astaxanthin in rats following exposure to graded levels in the feed. Comp Biochem Physiol C Toxicol Pharmacol (2006) 0.83
Direct extraction of astaxanthin from Haematococcus culture using vegetable oils. Biotechnol Lett (2007) 0.83
Pharmacokinetics and first-pass metabolism of astaxanthin in rats. Br J Nutr (2010) 0.83
Combined astaxanthin and fish oil supplementation improves glutathione-based redox balance in rat plasma and neutrophils. Chem Biol Interact (2012) 0.83
Storage stability and antioxidant activity of complex of astaxanthin with hydroxypropyl-β-cyclodextrin. Carbohydr Polym (2012) 0.83
Effects of astaxanthin on antioxidation in human aqueous humor. J Clin Biochem Nutr (2013) 0.83
Novel astaxanthin prodrug (CDX-085) attenuates thrombosis in a mouse model. Thromb Res (2010) 0.83
Astaxanthin ameliorates the redox imbalance in lymphocytes of experimental diabetic rats. Chem Biol Interact (2010) 0.82
Summative interaction between astaxanthin, Ginkgo biloba extract (EGb761) and vitamin C in suppression of respiratory inflammation: a comparison with ibuprofen. Phytother Res (2011) 0.82
Astaxanthine secured apoptotic death of PC12 cells induced by beta-amyloid peptide 25-35: its molecular action targets. J Med Food (2010) 0.82
Astaxanthin modulates age-associated mitochondrial dysfunction in healthy dogs. J Anim Sci (2012) 0.82
Astaxanthin-enriched-diet reduces blood pressure and improves cardiovascular parameters in spontaneously hypertensive rats. Pharmacol Res (2010) 0.82
Preventing the thermal degradation of astaxanthin through nanoencapsulation. Int J Pharm (2009) 0.82
Optimization of acidic extraction of astaxanthin from Phaffia rhodozyma. J Zhejiang Univ Sci B (2008) 0.82
Protective effects of Haematococcus astaxanthin on oxidative stress in healthy smokers. J Med Food (2011) 0.81
Upregulation of connexin 43 protein expression and increased gap junctional communication by water soluble disodium disuccinate astaxanthin derivatives. Cancer Lett (2004) 0.81
Effect of astaxanthin supplementation on inflammation and cardiac function in BALB/c mice. Anticancer Res (2010) 0.81
Astaxanthin enhances ATP-binding cassette transporter A1/G1 expressions and cholesterol efflux from macrophages. J Nutr Sci Vitaminol (Tokyo) (2012) 0.81
Effects of spray-drying and storage on astaxanthin content of Haematococcus pluvialis biomass. World J Microbiol Biotechnol (2011) 0.81
Astaxanthin stimulates cell-mediated and humoral immune responses in cats. Vet Immunol Immunopathol (2011) 0.80
Enhanced cognitive function and antidepressant-like effects after krill oil supplementation in rats. Lipids Health Dis (2013) 0.80
Antiaging effects of astaxanthin-rich alga Haematococcus pluvialis on fruit flies under oxidative stress. J Agric Food Chem (2013) 0.79
Acute and chronic administration of disodium disuccinate astaxanthin (Cardax) produces marked cardioprotection in dog hearts. Mol Cell Biochem (2005) 0.79
Antioxidative and antiproliferative effects of astaxanthin during the initiation stages of 1,2-dimethyl hydrazine-induced experimental colon carcinogenesis. Fundam Clin Pharmacol (2009) 0.79
Beneficial effect of astaxanthin on 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced liver injury in rats. Toxicol Ind Health (2012) 0.78
Effect of an oral astaxanthin prodrug (CDX-085) on lipoprotein levels and progression of atherosclerosis in LDLR(-/-) and ApoE(-/-) mice. Atherosclerosis (2012) 0.78
Shrimp waste extract and astaxanthin: rat alveolar macrophage, oxidative stress and inflammation. J Food Sci (2012) 0.78
Astaxanthin diminishes gap junctional intercellular communication in primary human fibroblasts. J Nutr (2005) 0.78
High-level production of astaxanthin by Xanthophyllomyces dendrorhous mutant JH1 using statistical experimental designs. Biosci Biotechnol Biochem (2005) 0.78
Combined fish oil and astaxanthin supplementation modulates rat lymphocyte function. Eur J Nutr (2011) 0.78
Effect of total secondary carotenoids extracts from Chlorococcum sp on Helicobacter pylori-infected BALB/c mice. Int Immunopharmacol (2003) 0.78
Anticoagulatory and antiinflammatory effects of astaxanthin in diabetic rats. J Food Sci (2012) 0.77
Chemical stability of astaxanthin nanodispersions in orange juice and skimmed milk as model food systems. Food Chem (2013) 0.77