Published in Biophys J on June 01, 1987
Ion transport in a model gramicidin channel. Structure and thermodynamics. Biophys J (1991) 3.38
Structure and dynamics of a proton wire: a theoretical study of H+ translocation along the single-file water chain in the gramicidin A channel. Biophys J (1996) 2.61
Water and polypeptide conformations in the gramicidin channel. A molecular dynamics study. Biophys J (1989) 2.14
Ion-water and ion-polypeptide correlations in a gramicidin-like channel. A molecular dynamics study. Biophys J (1990) 1.77
The normal modes of the gramicidin-A dimer channel. Biophys J (1988) 1.59
A semi-microscopic Monte Carlo study of permeation energetics in a gramicidin-like channel: the origin of cation selectivity. Biophys J (1996) 1.38
Simulation of voltage-driven hydrated cation transport through narrow transmembrane channels. Biophys J (1987) 1.34
Application of Brownian motion theory to the analysis of membrane channel ionic trajectories calculated by molecular dynamics. Biophys J (1988) 1.08
Extended dipolar chain model for ion channels: electrostriction effects and the translocational energy barrier. Biophys J (1995) 1.04
Influence of a channel-forming peptide on energy barriers to ion permeation, viewed from a continuum dielectric perspective. Biophys J (1994) 0.97
Molecular dynamics studies of the interface between a model membrane and an aqueous solution. Biophys J (1991) 0.86
The gramicidin A channel: a review of its permeability characteristics with special reference to the single-file aspect of transport. J Membr Biol (1981) 4.79
Ion transfer across lipid membranes in the presence of gramicidin A. II. The ion selectivity. Biochim Biophys Acta (1972) 4.35
Structure and dynamics of ion transport through gramicidin A. Biophys J (1984) 4.33
Interaction of ions and water in gramicidin A channels: streaming potentials across lipid bilayer membranes. J Gen Physiol (1978) 2.73
Water permeability of gramicidin A-treated lipid bilayer membranes. J Gen Physiol (1978) 1.97
Molecular dynamics study of ion transport in transmembrane protein channels. Biophys Chem (1981) 1.43
A molecular theory of ion-conductng channels: a field-dependent transition between conducting and nonconducting conformations. Proc Natl Acad Sci U S A (1972) 1.32
Ion-bond forms of the gramicidin a transmembrane channel. Biophys J (1984) 1.24
Ion-specific diffusion rates through transmembrane protein channels. A molecular dynamics study. Biophys Chem (1983) 1.19
Molecular dynamics of ion transport through transmembrane model channels. Annu Rev Biophys Biophys Chem (1985) 1.19
Vibrational analysis of peptides, polypeptides, and proteins. XVIII. Conformational sensitivity of the alpha-helix spectrum: alpha I- and alpha II-poly(L-alanine). Biopolymers (1984) 1.14
Entropy effects on the ion-diffusion rate in transmembrane protein channels. Biophys Chem (1983) 1.13
Solvent effects in ionic transport through transmembrane protein channels. J Theor Biol (1985) 1.10
Vibrational analysis of the structure of crystalline gramicidin a. Biophys J (1984) 0.96
The effects of lipid environment, ion-binding and chemical modifications on the structure of the gramicidin transmembrane channel. Biophys J (1982) 0.91
Molecular interaction between the Strep-tag affinity peptide and its cognate target, streptavidin. J Mol Biol (1996) 2.10
Virtual reality modeling language in chemistry. J Mol Graph (1995) 1.92
Mutagenesis of a flexible loop in streptavidin leads to higher affinity for the Strep-tag II peptide and improved performance in recombinant protein purification. Protein Eng (1997) 1.85
One-step affinity purification of bacterially produced proteins by means of the "Strep tag" and immobilized recombinant core streptavidin. J Chromatogr A (1994) 1.57
The random peptide library-assisted engineering of a C-terminal affinity peptide, useful for the detection and purification of a functional Ig Fv fragment. Protein Eng (1993) 1.54
Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment. J Neurosci (2000) 1.45
Molecular dynamics study of ion transport in transmembrane protein channels. Biophys Chem (1981) 1.43
A new approach to analysis and display of local lipophilicity/hydrophilicity mapped on molecular surfaces. J Comput Aided Mol Des (1993) 1.36
Simulation of voltage-driven hydrated cation transport through narrow transmembrane channels. Biophys J (1987) 1.34
Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold. Proc Natl Acad Sci U S A (1999) 1.34
Texture mapping: a new tool for molecular graphics. J Mol Graph (1994) 1.31
Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured purkinje cell axons. J Neurosci (2000) 1.20
Ion-specific diffusion rates through transmembrane protein channels. A molecular dynamics study. Biophys Chem (1983) 1.19
Molecular dynamics of ion transport through transmembrane model channels. Annu Rev Biophys Biophys Chem (1985) 1.19
Entropy effects on the ion-diffusion rate in transmembrane protein channels. Biophys Chem (1983) 1.13
Ultrafast electron transfer in the complex between fluorescein and a cognate engineered lipocalin protein, a so-called anticalin. Biochemistry (2002) 1.12
Solvent effects in ionic transport through transmembrane protein channels. J Theor Biol (1985) 1.10
Glutathione S-transferase can be used as a C-terminal, enzymatically active dimerization module for a recombinant protease inhibitor, and functionally secreted into the periplasm of Escherichia coli. Protein Sci (1997) 1.10
Engineered Fv fragments as a tool for the one-step purification of integral multisubunit membrane protein complexes. Biotechnology (N Y) (1995) 1.05
Immobilization of histidine-tagged proteins on gold surfaces using chelator thioalkanes. Biosens Bioelectron (1999) 1.02
An engineered lipocalin specific for CTLA-4 reveals a combining site with structural and conformational features similar to antibodies. Proc Natl Acad Sci U S A (2009) 1.01
Expression of functional antibody Fv and Fab fragments in Escherichia coli. Methods Enzymol (1989) 0.97
Bacterially produced apolipoprotein D binds progesterone and arachidonic acid, but not bilirubin or E-3M2H. J Mol Recognit (2001) 0.92
A novel type of receptor protein, based on the lipocalin scaffold, with specificity for digoxigenin. J Mol Biol (2000) 0.92
Grafting of a high-affinity Zn(II)-binding site on the beta-barrel of retinol-binding protein results in enhanced folding stability and enables simplified purification. Biochemistry (1994) 0.92
An engineered IN-1 F(ab) fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing activity. Protein Eng (2002) 0.90
Rapid expression cloning of human immunoglobulin Fab fragments for the analysis of antigen specificity of B cell lymphomas and anti-idiotype lymphoma vaccination. J Immunol Methods (1999) 0.89
Bifunctional and multimeric complexes of streptavidin fused to single chain antibodies (scFv). J Immunol Methods (1995) 0.89
Colony assays for antibody fragments expressed in bacteria. J Immunol Methods (1991) 0.87
The bilin-binding protein of Pieris brassicae. cDNA sequence and regulation of expression reveal distinct features of this insect pigment protein. Eur J Biochem (1994) 0.86
Molecular dynamics studies of the interface between a model membrane and an aqueous solution. Biophys J (1991) 0.86
The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment. J Mol Biol (1997) 0.86
Retrograde regulation of growth-associated gene expression in adult rat Purkinje cells by myelin-associated neurite growth inhibitory proteins. J Neurosci (1998) 0.86
Sequence analysis and bacterial production of the anti-c-myc antibody 9E10: the V(H) domain has an extended CDR-H3 and exhibits unusual solubility. FEBS Lett (1997) 0.85
Self similarity of protein surfaces. Biophys J (1992) 0.84
Intracellular expression of a cloned antibody fragment interferes with hepatitis B virus surface antigen secretion. Biochem Biophys Res Commun (1999) 0.84
Use of an albumin-binding domain for the selective immobilisation of recombinant capture antibody fragments on ELISA plates. J Immunol Methods (1998) 0.83
Fermenter production of an artificial fab fragment, rationally designed for the antigen cystatin, and its optimized crystallization through constant domain shuffling. Proteins (1995) 0.83
Improved folding of apo-retinol-binding protein in the periplasm of Escherichia coli: positive influences of dsbC coexpression and of an amino acid exchange in the vitamin A binding site. Protein Eng (1998) 0.82
Functional expression of the uncomplexed serum retinol-binding protein in Escherichia coli. Ligand binding and reversible unfolding characteristics. J Mol Biol (1993) 0.82
The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model. J Mol Biol (1994) 0.82
On the origins of tumor mutations in cancer genes: insights from the p53 gene. Mutat Res (1998) 0.81
The Escherichia coli-derived Fab fragment of the IgM/kappa antibody IN-1 recognizes and neutralizes myelin-associated inhibitors of neurite growth. Eur J Biochem (1996) 0.80
Single-step purification of a bacterially expressed antibody Fv fragment by immobilized metal affinity chromatography in the presence of betaine. J Chromatogr A (1993) 0.80
A Zn(II)-binding site engineered into retinol-binding protein exhibits metal-ion specificity and allows highly efficient affinity purification with a newly designed metal ligand. Chem Biol (1996) 0.79
Duocalins: engineered ligand-binding proteins with dual specificity derived from the lipocalin fold. Biol Chem (2001) 0.78
Use of thiophilic adsorption chromatography for the one-step purification of a bacterially produced antibody F(ab) fragment without the need for an affinity tag. Protein Expr Purif (1999) 0.78
Engineering of antibodies with a known three-dimensional structure. Cold Spring Harb Symp Quant Biol (1987) 0.78
Investigation of a tetracycline-regulated phage display system. Protein Eng (1999) 0.77
Properties of FV and Fab fragments of the antibody McPC603 expressed in E. coli. Behring Inst Mitt (1990) 0.76
Quantification and visualization of molecular surface flexibility. J Mol Graph (1995) 0.75
Triangulation algorithms for the representation of molecular surface properties. J Comput Aided Mol Des (1990) 0.75
Hausdorff dimension as a quantification of local roughness of protein surfaces. J Chem Inf Comput Sci (1992) 0.75
Molecular modeling information transfer with VRML: from small molecules to large systems in bioscience. Pac Symp Biocomput (1998) 0.75
Regeneration of auditory nerve following complete sectioning and intrathecal application of the IN-1 antibody. Acta Neurochir (Wien) (2002) 0.75
3D molecular graphics on the World Wide Web. Pac Symp Biocomput (1996) 0.75
Segmentation of protein surfaces using fuzzy logic. J Mol Graph (1994) 0.75
New fuzzy logic strategies for bio-molecular recognition. SAR QSAR Environ Res (2004) 0.75
Localization and quantification of hydrophobicity: the molecular free energy density (MolFESD) concept and its application to sweetness recognition. J Comput Aided Mol Des (2000) 0.75