Published in Sci Rep on January 16, 2014
Hallmarks of cancer: the next generation. Cell (2011) 140.01
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell (1995) 21.15
Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer (2003) 15.17
Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging (1999) 13.26
The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes. Science (1998) 10.83
Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet (2004) 8.30
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature (2009) 7.24
Perturbations of the AKT signaling pathway in human cancer. Oncogene (2005) 6.64
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell (2005) 4.30
Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J (2007) 3.91
Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase. J Biol Chem (1997) 3.09
Encoding and decoding cellular information through signaling dynamics. Cell (2013) 2.96
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat Immunol (2012) 2.72
Modeling a snap-action, variable-delay switch controlling extrinsic cell death. PLoS Biol (2008) 2.63
Design of genetic networks with specified functions by evolution in silico. Proc Natl Acad Sci U S A (2004) 2.60
Cross-talk and decision making in MAP kinase pathways. Nat Genet (2007) 2.52
Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability. PLoS Comput Biol (2006) 2.30
Cancer: a Systems Biology disease. Biosystems (2006) 2.29
AKT signaling in normal and malignant cells. Oncogene (2005) 2.14
Measuring and modeling apoptosis in single cells. Cell (2011) 2.10
Tailoring T-cell receptor signals by proximal negative feedback mechanisms. Nat Rev Immunol (2008) 2.06
Bistability and oscillations in the Huang-Ferrell model of MAPK signaling. PLoS Comput Biol (2007) 1.93
Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance. Biochem Soc Trans (2012) 1.92
Control of MAPK signalling: from complexity to what really matters. Oncogene (2005) 1.82
Processive phosphorylation of ERK MAP kinase in mammalian cells. Proc Natl Acad Sci U S A (2011) 1.55
Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells. Nat Rev Cancer (2011) 1.51
Evolution of robustness to noise and mutation in gene expression dynamics. PLoS One (2007) 1.51
Crosstalk via the NF-kappaB signaling system. Cytokine Growth Factor Rev (2008) 1.48
Navigating the network: signaling cross-talk in hematopoietic cells. Nat Immunol (2009) 1.48
Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. Mol Syst Biol (2012) 1.44
Cooperation between integrins and growth factor receptors in signaling and endocytosis. Annu Rev Cell Dev Biol (2011) 1.40
PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk. Mol Syst Biol (2009) 1.40
Integration of cytokine and heterologous receptor signaling pathways. Nat Immunol (2009) 1.36
Robustness of the bistable behavior of a biological signaling feedback loop. Chaos (2001) 1.26
Temporal coding of insulin action through multiplexing of the AKT pathway. Mol Cell (2012) 1.20
Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediators. J Biol Chem (2005) 1.10
Feedforward regulation ensures stability and rapid reversibility of a cellular state. Mol Cell (2013) 1.09
Capturing cell-fate decisions from the molecular signatures of a receptor-dependent signaling response. Mol Syst Biol (2007) 1.02
How selection affects phenotypic fluctuation. Mol Syst Biol (2009) 0.98
Quantifying crosstalk among interferon-γ, interleukin-12, and tumor necrosis factor signaling pathways within a TH1 cell model. Sci Signal (2012) 0.97
Integration of a phosphatase cascade with the mitogen-activated protein kinase pathway provides for a novel signal processing function. J Biol Chem (2009) 0.96
Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes. J Immunol (1998) 0.95
Cross signaling, cell specificity, and physiology. Am J Physiol Cell Physiol (2002) 0.94
Targeting self-renewal pathways in myeloid malignancies. Cell Commun Signal (2013) 0.87
Dwelling on T cell fate decisions. Cell (2013) 0.80
Cellular conference call: external feedback affects cell-fate decisions. Cell (2006) 0.79
TCR activation kinetics and feedback regulation in primary human T cells. Cell Commun Signal (2013) 0.79
Simulated evolution of signal transduction networks. PLoS One (2012) 0.77