Published in Psychopharmacology (Berl) on January 31, 2014
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment. Prog Neuropsychopharmacol Biol Psychiatry (2015) 0.87
Individual differences in the reinforcing and punishing effects of nicotine in rhesus monkeys. Psychopharmacology (Berl) (2015) 0.80
Clinical applications of hallucinogens: A review. Exp Clin Psychopharmacol (2016) 0.78
Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys. Addict Biol (2015) 0.78
Self-administration of cocaine and remifentanil by monkeys under concurrent-access conditions. Psychopharmacology (Berl) (2014) 0.75
Corrigendum: Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders. Front Pharmacol (2015) 0.75
Chemogenomics knowledgebase and systems pharmacology for hallucinogen target identification-Salvinorin A as a case study. J Mol Graph Model (2016) 0.75
Effects of nalfurafine on the reinforcing, thermal antinociceptive, and respiratory-depressant effects of oxycodone: modeling an abuse-deterrent opioid analgesic in rats. Psychopharmacology (Berl) (2017) 0.75
Evidence for addiction-like behavior in the rat. Science (2004) 5.19
Psychotomimesis mediated by kappa opiate receptors. Science (1986) 3.60
Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats. J Pharmacol Exp Ther (2005) 2.66
A choice procedure for drug reinforcers: cocaine and methylphenidate in the rhesus monkey. J Pharmacol Exp Ther (1975) 2.08
Concurrent performances: reinforcement by different doses of intravenous cocaine in rhesus monkeys. J Exp Anal Behav (1974) 1.78
U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking. Psychopharmacology (Berl) (1999) 1.54
Effects of kappa opioids on cocaine self-administration by rhesus monkeys. J Pharmacol Exp Ther (1997) 1.52
Interactions between kappa opioid agonists and cocaine. Preclinical studies. Ann N Y Acad Sci (2000) 1.50
Kappa opioid inhibition of morphine and cocaine self-administration in rats. Brain Res (1995) 1.49
Choice between heroin and food in nondependent and heroin-dependent rhesus monkeys: effects of naloxone, buprenorphine, and methadone. J Pharmacol Exp Ther (2006) 1.43
Effects of the plant-derived hallucinogen salvinorin A on basal dopamine levels in the caudate putamen and in a conditioned place aversion assay in mice: agonist actions at kappa opioid receptors. Psychopharmacology (Berl) (2005) 1.43
Effects of kappa opioid agonists on cocaine- and food-maintained responding by rhesus monkeys. J Pharmacol Exp Ther (1998) 1.42
Preclinical Determinants of Drug Choice under Concurrent Schedules of Drug Self-Administration. Adv Pharmacol Sci (2012) 1.34
Effects of punishment on choice between cocaine and food in rhesus monkeys. Psychopharmacology (Berl) (2005) 1.30
Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A. Pharmacol Rev (2011) 1.26
U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats. Neurosci Lett (1994) 1.24
Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens. Psychopharmacology (Berl) (2010) 1.24
Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans. J Pharmacol Exp Ther (2006) 1.12
Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats. Pharmacol Biochem Behav (2009) 1.11
Kappa opioids as potential treatments for stimulant dependence. AAPS J (2005) 1.08
Suppression of cocaine self-administration in monkeys: effects of delayed punishment. Psychopharmacology (Berl) (2011) 1.07
A novel choice method for studying drugs as punishers. Pharmacol Biochem Behav (2003) 1.06
Effect of the kappa opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Psychopharmacology (Berl) (2004) 1.04
Micro/kappa opioid interactions in rhesus monkeys: implications for analgesia and abuse liability. Exp Clin Psychopharmacol (2008) 1.00
Kappa opioid receptors on dopaminergic neurons are necessary for kappa-mediated place aversion. Neuropsychopharmacology (2013) 0.99
Histamine as a punisher in squirrel monkeys: effects of pentobarbital, chlordiazepoxide and H1- and H2-receptor antagonists on behavior and cardiovascular responses. J Pharmacol Exp Ther (1980) 0.98
The effects of electric shock on responding maintained by cocaine injections in a choice procedure in the rhesus monkey. Psychopharmacology (Berl) (1977) 0.96
Individual differences in the effects of environmental stimuli on cocaine choice in socially housed male cynomolgus monkeys. Psychopharmacology (Berl) (2011) 0.95
Suppression of cocaine self-administration by extinction and punishment. Pharmacol Biochem Behav (1974) 0.94
Differential effects of bremazocine on oral phencyclidine (PCP) self-administration in male and female rhesus monkeys. Exp Clin Psychopharmacol (2004) 0.93
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys: kappa opioid and serotonergic mechanisms. Psychopharmacology (Berl) (2009) 0.90
A choice procedure to assess the aversive effects of drugs in rodents. J Exp Anal Behav (2010) 0.88
Effects of H1-receptor antagonists on responding punished by histamine injection or electric shock presentation in squirrel monkeys. Psychopharmacology (Berl) (1986) 0.87
Cocaine self-administration punished by i.v. histamine in rat models of high and low drug abuse vulnerability: effects of saccharin preference, impulsivity, and sex. Physiol Behav (2013) 0.87
Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands. J Med Chem (2005) 2.13
Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil. J Pharmacol Exp Ther (2009) 1.88
Behavioral and neurochemical consequences of long-term intravenous self-administration of MDMA and its enantiomers by rhesus monkeys. Neuropsychopharmacology (2004) 1.71
A facile method for the preparation of deuterium labeled salvinorin A: synthesis of [2,2,2-2H3]-salvinorin A. Bioorg Med Chem Lett (2004) 1.60
Synthetic studies of neoclerodane diterpenoids from Salvia splendens and evaluation of Opioid Receptor affinity. Tetrahedron (2008) 1.53
Synthesis of salvinorin A analogues as opioid receptor probes. J Nat Prod (2006) 1.39
Effect of aripiprazole, a partial dopamine D2 receptor agonist, on increased rate of methamphetamine self-administration in rats with prolonged session duration. Neuropsychopharmacology (2007) 1.38
In vivo effects of amphetamine analogs reveal evidence for serotonergic inhibition of mesolimbic dopamine transmission in the rat. J Pharmacol Exp Ther (2011) 1.37
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: semisynthesis of salvinicins A and B and other chemical transformations of salvinorin A. J Nat Prod (2006) 1.36
Reactive oxygen and targeted antioxidant administration in endothelial cell mitochondria. J Biol Chem (2006) 1.35
Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. Biochem Pharmacol (2012) 1.32
Development of a rationally designed, low abuse potential, biogenic amine releaser that suppresses cocaine self-administration. J Pharmacol Exp Ther (2005) 1.29
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring. Bioorg Med Chem Lett (2006) 1.29
Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A. Pharmacol Rev (2011) 1.26
Delay discounting of saccharin in rhesus monkeys. Behav Processes (2009) 1.25
Effects of clomipramine on self-control choice in Lewis and Fischer 344 rats. Pharmacol Biochem Behav (2005) 1.24
A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence. Synapse (2007) 1.24
Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum. Org Lett (2005) 1.23
The reinforcing efficacy of psychostimulants in rhesus monkeys: the role of pharmacokinetics and pharmacodynamics. J Pharmacol Exp Ther (2003) 1.21
Salvinorin A: allosteric interactions at the mu-opioid receptor. J Pharmacol Exp Ther (2006) 1.21
Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction. Biochem Pharmacol (2007) 1.20
Human psychopharmacology and dose-effects of salvinorin A, a kappa opioid agonist hallucinogen present in the plant Salvia divinorum. Drug Alcohol Depend (2010) 1.20
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues. J Med Chem (2007) 1.18
Development of functionally selective, small molecule agonists at kappa opioid receptors. J Biol Chem (2013) 1.17
Estimating the relative reinforcing strength of (+/-)-3,4-methylenedioxymethamphetamine (MDMA) and its isomers in rhesus monkeys: comparison to (+)-methamphetamine. Psychopharmacology (Berl) (2006) 1.15
Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. Synapse (2005) 1.13
The generalized matching law as a predictor of choice between cocaine and food in rhesus monkeys. Psychopharmacology (Berl) (2002) 1.13
Unconditioned behavioral effects of the powerful kappa-opioid hallucinogen salvinorin A in nonhuman primates: fast onset and entry into cerebrospinal fluid. J Pharmacol Exp Ther (2008) 1.12
Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans. J Pharmacol Exp Ther (2006) 1.12
R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse. Biol Psychiatry (2012) 1.12
Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats. Pharmacol Biochem Behav (2009) 1.11
Effects of dose and infusion delay on cocaine self-administration choice in rhesus monkeys. Psychopharmacology (Berl) (2003) 1.08
Gedunin, a novel hsp90 inhibitor: semisynthesis of derivatives and preliminary structure-activity relationships. J Med Chem (2008) 1.07
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: exploration of the 1-position. Bioorg Med Chem Lett (2007) 1.07
The reinforcing efficacy of the dopamine reuptake inhibitor 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT) as measured by a progressive-ratio schedule and a choice procedure in rhesus monkeys. J Pharmacol Exp Ther (2002) 1.05
Herkinorin analogues with differential beta-arrestin-2 interactions. J Med Chem (2008) 1.03
Kappa opioids and the modulation of pain. Psychopharmacology (Berl) (2010) 1.03
Delay discounting in rhesus monkeys: equivalent discounting of more and less preferred sucrose concentrations. Learn Behav (2012) 1.02
Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.01
Self-administration of mixtures of fenfluramine and amphetamine by rhesus monkeys. Pharmacol Biochem Behav (2006) 1.00
Uptake, distribution and diffusivity of reactive fluorophores in cells: implications toward target identification. Mol Pharm (2010) 1.00
Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology. Drug Alcohol Depend (2011) 1.00
A reduced rate of in vivo dopamine transporter binding is associated with lower relative reinforcing efficacy of stimulants. Neuropsychopharmacology (2006) 0.99
Role of the increased noradrenergic neurotransmission in drug self-administration. Drug Alcohol Depend (2005) 0.99
Behavioral evaluation of modafinil and the abuse-related effects of cocaine in rhesus monkeys. Exp Clin Psychopharmacol (2010) 0.99
Dose-related effects of salvinorin A in humans: dissociative, hallucinogenic, and memory effects. Psychopharmacology (Berl) (2012) 0.97
Potential Drug Abuse Therapeutics Derived from the Hallucinogenic Natural Product Salvinorin A. Medchemcomm (2011) 0.97
Elevated level of metabotropic glutamate receptor 2/3 in the prefrontal cortex in major depression. Prog Neuropsychopharmacol Biol Psychiatry (2009) 0.97
Identification of a novel "almost neutral" micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor. Synapse (2010) 0.97
Evaluation of the reinforcing effects of atomoxetine in monkeys: comparison to methylphenidate and desipramine. Drug Alcohol Depend (2004) 0.96
Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen. Eur J Pharm Biopharm (2009) 0.96
Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression. J Biol Chem (2012) 0.96
Discovery of a novel selective kappa-opioid receptor agonist using crystal structure-based virtual screening. J Chem Inf Model (2013) 0.96
Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships. J Nat Prod (2007) 0.95
Self-administration of cocaine: scopolamine combinations by rhesus monkeys. Psychopharmacology (Berl) (2002) 0.93
Semisynthetic neoclerodanes as kappa opioid receptor probes. Bioorg Med Chem (2012) 0.93
Opioid receptor probes derived from cycloaddition of the hallucinogen natural product salvinorin A. J Nat Prod (2011) 0.92
Structure-Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide) Analogues. ACS Med Chem Lett (2010) 0.91
Self-administration of cocaine and nicotine mixtures by rhesus monkeys. Psychopharmacology (Berl) (2009) 0.90
Reinstatement of methamphetamine seeking in male and female rats treated with modafinil and allopregnanolone. Drug Alcohol Depend (2011) 0.90
Behavioral effects and central nervous system levels of the broadly available κ-agonist hallucinogen salvinorin A are affected by P-glycoprotein modulation in vivo. J Pharmacol Exp Ther (2012) 0.90
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. ACS Chem Neurosci (2012) 0.89
Self-administration of cocaine-antihistamine combinations: super-additive reinforcing effects. Eur J Pharmacol (2006) 0.89
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors. Brain Res Bull (2008) 0.88
Self-administration of (+)-methamphetamine and (+)-pseudoephedrine, alone and combined, by rhesus monkeys. Pharmacol Biochem Behav (2010) 0.87
Evaluation of the reinforcing and discriminative stimulus effects of 1,4-butanediol and gamma-butyrolactone in rhesus monkeys. Eur J Pharmacol (2003) 0.87
The discriminative effects of the kappa-opioid hallucinogen salvinorin A in nonhuman primates: dissociation from classic hallucinogen effects. Psychopharmacology (Berl) (2010) 0.87
The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates. J Pharmacol Exp Ther (2008) 0.86
(S)-N-(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a small molecule inhibitor probe for the study of respiratory syncytial virus infection. J Med Chem (2012) 0.86
Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression. Int J Neuropsychopharmacol (2010) 0.86
Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem J (2010) 0.86
Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues. J Med Chem (2014) 0.85
Chemical methods for the synthesis and modification of neoclerodane diterpenes. Bioorg Med Chem Lett (2009) 0.85
Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells. PLoS One (2009) 0.85
Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity. J Med Chem (2006) 0.84
Super-additive interaction of the reinforcing effects of cocaine and H1-antihistamines in rhesus monkeys. Pharmacol Biochem Behav (2008) 0.83
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors. Org Biomol Chem (2009) 0.82
Modafinil alone and in combination with low dose amphetamine does not establish conditioned place preference in male Sprague-Dawley rats. Exp Clin Psychopharmacol (2013) 0.81
Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter. Bioorg Med Chem (2006) 0.81
Assessment of the effects of contingent histamine injections on the reinforcing effectiveness of cocaine using behavioral economic and progressive-ratio designs. Psychopharmacology (Berl) (2014) 0.80
Assessment of ropinirole as a reinforcer in rhesus monkeys. Drug Alcohol Depend (2012) 0.80
A single injection of a novel κ opioid receptor agonist salvinorin A attenuates the expression of cocaine-induced behavioral sensitization in rats. Behav Pharmacol (2012) 0.80
Cannabinoid agonists increase the interaction between β-Arrestin 2 and ERK1/2 and upregulate β-Arrestin 2 and 5-HT(2A) receptors. Pharmacol Res (2012) 0.79
Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse. J Med Chem (2013) 0.79
Synthesis of neoclerodane diterpenes and their pharmacological effects. Top Curr Chem (2011) 0.79
New therapeutic potential for psychoactive natural products. Nat Prod Rep (2009) 0.79
The 2-methoxy methyl analogue of salvinorin A attenuates cocaine-induced drug seeking and sucrose reinforcements in rats. Eur J Pharmacol (2013) 0.78
Palladium-catalyzed transformations of salvinorin A, a neoclerodane diterpene from Salvia divinorum. Org Lett (2013) 0.78
Reinforcing effect of pseudoephedrine isomers and the mechanism of action. Eur J Pharmacol (2004) 0.78
DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods. Bioorg Med Chem (2006) 0.78
Self-administration of cocaine and remifentanil by monkeys: choice between single drugs and mixtures. Psychopharmacology (Berl) (2010) 0.78
Identification of unprecedented purine-containing compounds, the zingerines, from ginger rhizomes (Zingiber officinale Roscoe) using a phase-trafficking approach. Phytochemistry (2011) 0.78
Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model. Psychopharmacology (Berl) (2015) 0.78
Utilizing nature as a source of new probes for opioid pharmacology. Future Med Chem (2009) 0.77
Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: I. Expression and role of cytochromes P450. J Pharmacol Exp Ther (2006) 0.77
Dose and schedule determinants of cocaine choice under concurrent variable-interval schedules in rhesus monkeys. Psychopharmacology (Berl) (2004) 0.76
Synthetic studies on neoclerodane diterpenes from Salvia splendens: oxidative modifications of ring A. Tetrahedron (2009) 0.75
Enantioselective synthesis of (2R,3R)- and (2S,3S)-2- [(3-chlorophenyl)-(2-methoxyphenoxy)methyl]morpholine. Tetrahedron Asymmetry (2005) 0.75
Self-administration of cocaine and remifentanil by monkeys under concurrent-access conditions. Psychopharmacology (Berl) (2014) 0.75