Published in J Cell Sci on January 30, 2014
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Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. Nucleic Acids Res (2007) 2.02
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The RNA polymerase II carboxy-terminal domain (CTD) code. Chem Rev (2013) 1.82
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Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat. J Biol Chem (2005) 1.71
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The MAP1 family of microtubule-associated proteins. Genome Biol (2006) 1.60
Fifteen formins for an actin filament: a molecular view on the regulation of human formins. Biochim Biophys Acta (2010) 1.56
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Structural insights into the cyclin T1-Tat-TAR RNA transcription activation complex from EIAV. Nat Struct Mol Biol (2008) 1.36
Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux. J Infect Dis (2010) 1.34
Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1. J Biol Chem (2005) 1.30
HIV-1 Nef membrane association depends on charge, curvature, composition and sequence. Nat Chem Biol (2009) 1.29
RabGEFs are a major determinant for specific Rab membrane targeting. J Cell Biol (2013) 1.26
Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells. J Cell Biol (2007) 1.25
Biochemical indication for myristoylation-dependent conformational changes in HIV-1 Nef. Biochemistry (2006) 1.24
MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain. Curr Biol (2004) 1.22
Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef. Virology (2006) 1.21
Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein beta-catenin with the scaffolding protein MAGI-2. J Biol Chem (2004) 1.20
The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing. J Biol Chem (2008) 1.20
Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function. J Leukoc Biol (2007) 1.17
Conformational states of human rat sarcoma (Ras) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis. J Biol Chem (2010) 1.12
Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb. Proc Natl Acad Sci U S A (2007) 1.09
Human immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains. Retrovirology (2007) 1.08
Biophysical analysis of the interaction of Rab6a GTPase with its effector domains. J Biol Chem (2008) 1.05
Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development. Mol Cell Neurosci (2006) 1.02
Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly. Traffic (2011) 1.02
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Processing of naturally occurring sense/antisense transcripts of the vertebrate Slc34a gene into short RNAs. Physiol Genomics (2008) 0.98
Protective effects of the mTOR inhibitor everolimus on cytoskeletal injury in human podocytes are mediated by RhoA signaling. PLoS One (2013) 0.98
Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains. Angew Chem Int Ed Engl (2010) 0.96
FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers. J Cell Sci (2013) 0.96
DLC1 activation requires lipid interaction through a polybasic region preceding the RhoGAP domain. Mol Biol Cell (2009) 0.94
RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B. J Immunol (2009) 0.94
Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS One (2011) 0.94
Cyclin box structure of the P-TEFb subunit cyclin T1 derived from a fusion complex with EIAV tat. J Mol Biol (2007) 0.93
Reacquisition of Nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee host. Cell Host Microbe (2012) 0.92
Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates. J Biol Chem (2012) 0.92
Complex formation and light activation in membrane-embedded sensory rhodopsin II as seen by solid-state NMR spectroscopy. Structure (2010) 0.92
Tropomodulins are negative regulators of neurite outgrowth. Eur J Cell Biol (2010) 0.91
Farnesylation of the SNARE protein Ykt6 increases its stability and helical folding. J Mol Biol (2008) 0.91
NMR spectroscopic investigation of early events in IAPP amyloid fibril formation. Chembiochem (2009) 0.90
Oligomerization of the diaphanous-related formin FHOD1 requires a coiled-coil motif critical for its cytoskeletal and transcriptional activities. FEBS Lett (2005) 0.89
Optimized chimeras between kinase-inactive mutant Cdk9 and truncated cyclin T1 proteins efficiently inhibit Tat transactivation and human immunodeficiency virus gene expression. J Virol (2002) 0.88
Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA. J Mol Biol (2009) 0.88
Extracellular HIV-1 Nef increases migration of monocytes. Exp Cell Res (2006) 0.88
Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ T cell counts in viremic HIV-2 infection. J Virol (2012) 0.88
HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2. PLoS One (2011) 0.87
A minimal chimera of human cyclin T1 and tat binds TAR and activates human immunodeficiency virus transcription in murine cells. J Virol (2002) 0.87
Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition. Mol Cell Biol (2012) 0.87
Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function. Retrovirology (2012) 0.87
Migratory potential of rheumatoid arthritis synovial fibroblasts: additional perspectives. Cell Cycle (2010) 0.85
Comparison of design strategies for promotion of beta-peptide 14-helix stability in water. Chembiochem (2008) 0.85
Facile synthesis of thiol-reactive Cy3 and Cy5 derivatives with enhanced water solubility. Bioconjug Chem (2002) 0.84
Dominant negative mutant cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat. Retrovirology (2008) 0.84
Biochips for cell biology by combined dip-pen nanolithography and DNA-directed protein immobilization. Small (2013) 0.83
Observation of slow dynamic exchange processes in Ras protein crystals by 31P solid state NMR spectroscopy. J Mol Biol (2002) 0.83
High-affinity target binding engineered via fusion of a single-domain antibody fragment with a ligand-tailored SH3 domain. PLoS One (2012) 0.82
Nef surfaces: where to interfere with function. Curr HIV Res (2011) 0.82
A protein-interaction array inside a living cell. Angew Chem Int Ed Engl (2013) 0.82
Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C. J Biol Chem (2011) 0.81
A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1. Biochemistry (2010) 0.81
Mutation in a winged-helix DNA-binding motif causes atypical bare lymphocyte syndrome. Nat Immunol (2002) 0.81
Regulation of the NPT gene by a naturally occurring antisense transcript. Cell Biochem Biophys (2002) 0.81
Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53. Clin Cancer Res (2005) 0.81
A bioorthogonal small-molecule-switch system for controlling protein function in live cells. Angew Chem Int Ed Engl (2014) 0.80
HIV-1 Nef perturbs artificial membranes: investigation of the contribution of the myristoyl anchor. Biophys J (2009) 0.80
Preparation of biomolecule microstructures and microarrays by thiol-ene photoimmobilization. Chembiochem (2010) 0.80
Direct observation of microtubule pushing by cortical dynein in living cells. Mol Biol Cell (2013) 0.79
Synthesis, characterization and application of two nucleoside triphosphate analogues, GTPgammaNH(2) and GTPgammaF. Eur J Biochem (2002) 0.78
NMR assignment of the Cyclin T-binding domain of human Hexim1. J Biomol NMR (2006) 0.78
Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1. J Mol Biol (2011) 0.78
Configurable low-cost plotter device for fabrication of multi-color sub-cellular scale microarrays. Small (2014) 0.78
Formation of Tat-TAR containing ribonucleoprotein complexes for biochemical and structural analyses. Methods (2010) 0.78
Exogenous nef induces proinflammatory signaling events in murine macrophages. Viral Immunol (2012) 0.77
Mechanistic insights into the translocation of full length HIV-1 Tat across lipid membranes. Biochim Biophys Acta (2011) 0.77
A morphometric screen identifies specific roles for microtubule-regulating genes in neuronal development of P19 stem cells. PLoS One (2013) 0.77
Selective chemical imaging of static actin in live cells. J Am Chem Soc (2012) 0.76
1H, 15N, and 13C assignments of the N-terminal activation domain of Dictyostelium discoideum Formin C. Biomol NMR Assign (2010) 0.76
Positional screening and NMR structure determination of side-chain-to-side-chain cyclized β3-peptides. Org Biomol Chem (2011) 0.76
Purification, crystallization and preliminary structural characterization of the N-terminal region of the human formin-homology protein FHOD1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.75
Divergent solid-phase synthesis of natural product-inspired bipartite cyclodepsipeptides: total synthesis of seragamide A. Chemistry (2015) 0.75