Clinical and molecular studies reveal a PSEN1 mutation (L153V) in a Peruvian family with early-onset Alzheimer's disease.

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Published in Neurosci Lett on February 02, 2014

Authors

Mario R Cornejo-Olivas1, Chang-En Yu2, Pilar Mazzetti3, Ignacio F Mata4, Maria Meza5, Saul Lindo-Samanamud6, James B Leverenz7, Thomas D Bird8

Author Affiliations

1: Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; Northern Pacific Global Health Research Fellows Training Consortium, Bethesda, MD, United States. Electronic address: mario.cornejo.o@incngen.org.pe.
2: Geriatric Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, United States.
3: Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru.
4: Parkinson's Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, United States; Department of Neurology, University of Washington, Seattle, WA, United States.
5: School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru.
6: Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru.
7: Geriatric Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, United States; Mental Illness Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, United States; Parkinson's Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, United States; Department of Neurology, University of Washington, Seattle, WA, United States; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
8: Geriatric Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, United States; Parkinson's Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, United States; Department of Neurology, University of Washington, Seattle, WA, United States; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.

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