1
|
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.
|
J Clin Invest
|
2009
|
2.28
|
2
|
SPDEF regulates goblet cell hyperplasia in the airway epithelium.
|
J Clin Invest
|
2007
|
1.96
|
3
|
Mouse lysozyme M is important in pulmonary host defense against Klebsiella pneumoniae infection.
|
Am J Respir Crit Care Med
|
2003
|
1.81
|
4
|
Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis.
|
Am J Physiol Lung Cell Mol Physiol
|
2003
|
1.53
|
5
|
EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis.
|
Am J Physiol Lung Cell Mol Physiol
|
2008
|
1.51
|
6
|
Retracted
Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice.
|
Am J Respir Cell Mol Biol
|
2010
|
1.44
|
7
|
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.
|
Am J Respir Cell Mol Biol
|
2007
|
1.29
|
8
|
Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies.
|
Expert Opin Ther Targets
|
2010
|
1.29
|
9
|
Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.
|
Am J Respir Cell Mol Biol
|
2007
|
1.19
|
10
|
Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma.
|
Am J Physiol Lung Cell Mol Physiol
|
2010
|
1.12
|
11
|
Signaling pathways in the epithelial origins of pulmonary fibrosis.
|
Cell Cycle
|
2010
|
1.10
|
12
|
Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis.
|
Am J Pathol
|
2009
|
1.07
|
13
|
Surfactant protein D influences surfactant ultrastructure and uptake by alveolar type II cells.
|
Am J Physiol Lung Cell Mol Physiol
|
2004
|
1.06
|
14
|
Reversibility of pulmonary abnormalities by conditional replacement of surfactant protein D (SP-D) in vivo.
|
J Biol Chem
|
2002
|
1.01
|
15
|
Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice.
|
Am J Respir Cell Mol Biol
|
2009
|
1.00
|
16
|
Acute lung injury: functional genomics and genetic susceptibility.
|
Chest
|
2002
|
1.00
|
17
|
Surfactant protein-D regulates soluble CD14 through matrix metalloproteinase-12.
|
J Immunol
|
2005
|
0.97
|
18
|
Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection.
|
Am J Physiol Lung Cell Mol Physiol
|
2009
|
0.96
|
19
|
Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha.
|
Am J Respir Cell Mol Biol
|
2002
|
0.96
|
20
|
Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice.
|
J Immunol
|
2008
|
0.96
|
21
|
Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis.
|
Am J Physiol Lung Cell Mol Physiol
|
2007
|
0.94
|
22
|
Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice.
|
Am J Respir Cell Mol Biol
|
2013
|
0.93
|
23
|
Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity.
|
Am J Respir Crit Care Med
|
2014
|
0.93
|
24
|
Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation.
|
J Clin Invest
|
2015
|
0.92
|
25
|
Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha.
|
Am J Physiol Lung Cell Mol Physiol
|
2003
|
0.91
|
26
|
Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis.
|
Respir Res
|
2012
|
0.91
|
27
|
The murine SP-C promoter directs type II cell-specific expression in transgenic mice.
|
Am J Physiol Lung Cell Mol Physiol
|
2004
|
0.90
|
28
|
In vivo measurements of changes in respiratory mechanics with age in mice deficient in surfactant protein D.
|
Pediatr Res
|
2003
|
0.90
|
29
|
Neither SP-A nor NH2-terminal domains of SP-A can substitute for SP-D in regulation of alveolar homeostasis.
|
Am J Physiol Lung Cell Mol Physiol
|
2006
|
0.90
|
30
|
Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.
|
Am J Respir Crit Care Med
|
2009
|
0.89
|
31
|
Surfactant protein D regulates the cell surface expression of alveolar macrophage beta(2)-integrins.
|
Am J Physiol Lung Cell Mol Physiol
|
2006
|
0.86
|
32
|
The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo.
|
J Biol Chem
|
2002
|
0.86
|
33
|
Altered postnatal lung development in C3H/HeJ mice.
|
Pediatr Res
|
2006
|
0.85
|
34
|
Surfactant-associated protein B is critical to survival in nickel-induced injury in mice.
|
Am J Respir Cell Mol Biol
|
2009
|
0.85
|
35
|
Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury.
|
Respir Res
|
2013
|
0.83
|
36
|
Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis.
|
Am J Physiol Lung Cell Mol Physiol
|
2014
|
0.83
|
37
|
TGF-alpha perturbs surfactant homeostasis in vivo.
|
Am J Physiol Lung Cell Mol Physiol
|
2005
|
0.82
|
38
|
Surfactant protein A regulates surfactant phospholipid clearance after LPS-induced injury in vivo.
|
Am J Physiol Lung Cell Mol Physiol
|
2002
|
0.81
|
39
|
Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease.
|
J Appl Physiol (1985)
|
2011
|
0.80
|
40
|
Pulmonary surfactant and inflammation in septic adult mice: role of surfactant protein A.
|
J Appl Physiol (1985)
|
2002
|
0.76
|