Published in Biomark Med on January 01, 2014
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Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage. Genome Res (2010) 2.61
Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. Genome Res (2004) 2.29
Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics (2011) 2.24
Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells (2006) 2.18
A prospective evaluation of pain associated with stone passage, stents, and stent removal using a visual analog scale. Urology (2013) 2.05
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Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells. Stem Cells (2005) 1.68
New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes. Genome Res (2003) 1.65
Kidney fusion anomalies revisited: clinical and radiological analysis of 209 cases of crossed fused ectopia and horseshoe kidney. BJU Int (2008) 1.61
Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells. Toxicol Sci (2010) 1.57
Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA. Bioinformatics (2011) 1.46
Toxicogenomics directory of chemically exposed human hepatocytes. Arch Toxicol (2014) 1.43
Relationship between radical generation by urban ambient particulate matter and pulmonary function of school children. J Toxicol Environ Health A (2006) 1.41
MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments. Bioinformatics (2013) 1.38
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Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J (2010) 1.27
Reverse engineering of gene regulatory networks: a comparative study. EURASIP J Bioinform Syst Biol (2009) 1.22
Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification. Toxicol Sci (2010) 1.20
Evidence mining and novelty assessment of protein-protein interactions with the ConsensusPathDB plugin for Cytoscape. Bioinformatics (2010) 1.19
A global view of gene expression in lithium and zinc treated sea urchin embryos: new components of gene regulatory networks. Genome Biol (2007) 1.19
Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays. BMC Genomics (2004) 1.16
Resources, standards and tools for systems biology. Brief Funct Genomic Proteomic (2007) 1.15
Renal tumour size measured radiologically before surgery is an unreliable variable for predicting histopathological features: benign tumours are not necessarily small. BJU Int (2007) 1.15
Decreased human semen quality and organochlorine compounds in blood. Hum Reprod (2002) 1.14
DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer. PLoS Genet (2013) 1.13
Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research. Environ Health Perspect (2013) 1.13
Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon. Mol Nutr Food Res (2009) 1.12
GeNGe: systematic generation of gene regulatory networks. Bioinformatics (2009) 1.11
Generation, annotation, evolutionary analysis, and database integration of 20,000 unique sea urchin EST clusters. Genome Res (2003) 1.11
In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach. BMC Genomics (2009) 1.09
Meta-analysis approach identifies candidate genes and associated molecular networks for type-2 diabetes mellitus. BMC Genomics (2008) 1.08
Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents. Toxicol Sci (2005) 1.05
Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin. J Invest Dermatol (2005) 1.05
In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers. Nutrition (2008) 1.05
Biotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changes. Drug Discov Today (2010) 1.04
Gene expression variation in Down's syndrome mice allows prioritization of candidate genes. Genome Biol (2007) 1.04
Nodal signaling activates differentiation genes during zebrafish gastrulation. Dev Biol (2007) 1.03
Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity. Toxicol Sci (2011) 1.02
Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs. Carcinogenesis (2006) 1.02
Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process. BMC Bioinformatics (2005) 1.01
Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro. Aging Cell (2006) 1.01
Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes. BMC Genomics (2011) 1.00
Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. PLoS Comput Biol (2011) 0.99
Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression. Physiol Genomics (2007) 0.99
Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time. Toxicol Sci (2009) 0.99
Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes. Drug Metab Dispos (2009) 0.99
A second generation radiation hybrid map to aid the assembly of the bovine genome sequence. BMC Genomics (2006) 0.99
RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene. Toxicol Sci (2012) 0.98
Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo. Genome Res (2004) 0.98
Meeting report: Validation of toxicogenomics-based test systems: ECVAM-ICCVAM/NICEATM considerations for regulatory use. Environ Health Perspect (2006) 0.98
Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. Toxicol Sci (2009) 0.97
alpha-Blockers improve chronic ischaemia of the lower urinary tract in patients with lower urinary tract symptoms. BJU Int (2007) 0.97
Genomic analysis suggests higher susceptibility of children to air pollution. Carcinogenesis (2008) 0.96
Cigarette smoke-induced transgenerational alterations in genome stability in cord blood of human F1 offspring. FASEB J (2012) 0.95
Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis. Toxicol Sci (2009) 0.95
ARH: predicting splice variants from genome-wide data with modified entropy. Bioinformatics (2009) 0.95
LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Nat Commun (2013) 0.94
DEFOG: a practical scheme for deciphering families of genes. Genomics (2002) 0.92
Protection by quercetin and quercetin-rich fruit juice against induction of oxidative DNA damage and formation of BPDE-DNA adducts in human lymphocytes. Mutat Res (2005) 0.91
Interindividual variations in DNA adduct levels assessed by analysis of multiple genetic polymorphisms in smokers. Cancer Epidemiol Biomarkers Prev (2006) 0.91
Toenails: an easily accessible and long-term stable source of DNA for genetic analyses in large-scale epidemiological studies. Clin Chem (2007) 0.89
Correlation of leukocytospermia with clinical infection and the positive effect of antiinflammatory treatment on semen quality. Fertil Steril (2006) 0.89
IntScore: a web tool for confidence scoring of biological interactions. Nucleic Acids Res (2012) 0.88
Simulation of DNA array hybridization experiments and evaluation of critical parameters during subsequent image and data analysis. BMC Bioinformatics (2002) 0.88
Dynamics of biological systems: role of systems biology in medical research. Expert Rev Mol Diagn (2006) 0.88
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells. Arch Toxicol (2012) 0.88
Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn). Toxicol Sci (2011) 0.88
Evidence of female-specific glial deficits in the hippocampus in a mouse model of prenatal stress. Eur Neuropsychopharmacol (2010) 0.87
Cluster-based assessment of protein-protein interaction confidence. BMC Bioinformatics (2012) 0.87
Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models. Carcinogenesis (2013) 0.87
The Post-Ureteroscopic Lesion Scale (PULS): a multicenter video-based evaluation of inter-rater reliability. World J Urol (2013) 0.86
Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers. Carcinogenesis (2007) 0.86
Pre-exposure to low doses: modulation of X-ray-induced dna damage and repair? Radiat Res (2005) 0.86
Gene polymorphisms and prostate cancer: the evidence. BJU Int (2009) 0.86
Prediction in the face of uncertainty: a Monte Carlo-based approach for systems biology of cancer treatment. Mutat Res (2012) 0.85
Neutrophil-mediated formation of carcinogenic N-nitroso compounds in an in vitro model for intestinal inflammation. Toxicol Lett (2004) 0.85
Generation of free radicals and induction of DNA adducts by activation of heterocyclic aromatic amines via different metabolic pathways in vitro. Mol Carcinog (2002) 0.85
Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets. Toxicol Sci (2010) 0.85
Synchronous bilateral malignant mesothelioma of tunica vaginalis testis: early diagnosis. Urology (2004) 0.84
Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon. Food Chem Toxicol (2011) 0.84
Gender-specific transcriptomic response to environmental exposure in Flemish adults. Environ Mol Mutagen (2013) 0.84
Reduction of colonic inflammation in HLA-B27 transgenic rats by feeding Marie Ménard apples, rich in polyphenols. Br J Nutr (2009) 0.84
DIPSBC--data integration platform for systems biology collaborations. BMC Bioinformatics (2012) 0.84
Global gene expression analysis in cord blood reveals gender-specific differences in response to carcinogenic exposure in utero. Cancer Epidemiol Biomarkers Prev (2012) 0.84
Simultaneous genotyping of nine polymorphisms in xenobiotic-metabolizing enzymes by multiplex PCR amplification and single base extension. Clin Chem (2004) 0.83
Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells. Toxicol Sci (2011) 0.83
Oxidative stress and epididymal sperm transport, motility and morphological defects. Eur J Obstet Gynecol Reprod Biol (2009) 0.83
Discriminative protection against hydroxyl and superoxide anion radicals by quercetin in human leucocytes in vitro. Toxicol In Vitro (2007) 0.82
Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity. Toxicol In Vitro (2012) 0.82
Molecular characterization of cultured adult human liver progenitor cells. Tissue Eng Part C Methods (2010) 0.82
N-nitroso compound exposure-associated transcriptomic profiles are indicative of an increased risk for colorectal cancer. Cancer Lett (2011) 0.82
Modulation of nucleotide excision repair in human lymphocytes by genetic and dietary factors. Br J Nutr (2009) 0.82
Urinary continence after radical prostatectomy: the patient perspective. Can J Urol (2011) 0.81